dehydroepiandrosterone has been researched along with Atypical Ductal Hyperplasia in 4 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reports that MCF-7 human breast cancer cells can transform both estrone (E1)1 to estradiol (E2) and dehydroepiandrosterone (DHEA) to the estrogenic steroid 5-androstenediol (AED), have prompted us to investigate the 17-ketosteroid reductase activities (17-KSR's) which mediate these potentially important reactions." | 5.28 | Dehydroepiandrosterone and estrone 17-ketosteroid reductases in MCF-7 human breast cancer cells. ( Hinkhouse, M; MacIndoe, JH; Woods, G, 1990) |
| "In order to determine whether human mammary tumours could contribute to cholesterol and dehydroepiandrosterone biosynthesis in breast cancer patients, incubations of homogenates of infiltrating ductal carcinoma were carried out separately with 2-14C acetate (patient, n = 6; 21-80 years) and 7n-3H pregnenolone (patient, n = 5, 36-74 years) as substrates." | 3.67 | Steroidogenic expression of delta 5-3 beta-hydroxy pathway of androgen biosynthesis by human breast carcinoma. ( Gunasegaram, R; Kottegoda, SR; Loganath, A; Peh, KL; Ratnam, SS; Thiagaraj, D, 1986) |
| "Reports that MCF-7 human breast cancer cells can transform both estrone (E1)1 to estradiol (E2) and dehydroepiandrosterone (DHEA) to the estrogenic steroid 5-androstenediol (AED), have prompted us to investigate the 17-ketosteroid reductase activities (17-KSR's) which mediate these potentially important reactions." | 1.28 | Dehydroepiandrosterone and estrone 17-ketosteroid reductases in MCF-7 human breast cancer cells. ( Hinkhouse, M; MacIndoe, JH; Woods, G, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Falany, CN | 1 |
| He, D | 1 |
| Dumas, N | 1 |
| Frost, AR | 1 |
| Falany, JL | 1 |
| MacIndoe, JH | 1 |
| Hinkhouse, M | 1 |
| Woods, G | 1 |
| Gunasegaram, R | 1 |
| Loganath, A | 1 |
| Peh, KL | 1 |
| Thiagaraj, D | 1 |
| Kottegoda, SR | 1 |
| Ratnam, SS | 1 |
| Miller, WR | 1 |
| Forrest, AP | 1 |
| Hamilton, T | 1 |
4 other studies available for dehydroepiandrosterone and Atypical Ductal Hyperplasia
| Article | Year |
|---|---|
Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization.
Topics: Amino Acid Sequence; Animals; Breast; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cel | 2006 |
Dehydroepiandrosterone and estrone 17-ketosteroid reductases in MCF-7 human breast cancer cells.
Topics: 17-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Androstenediol; Breast Neoplasms; Carcino | 1990 |
Steroidogenic expression of delta 5-3 beta-hydroxy pathway of androgen biosynthesis by human breast carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; Acetyl Coenzyme A; Adult; Aged; Androgens; Breast Neoplasms; Carcinoma | 1986 |
Steroid metabolism by human breast and rat mammary carcinomata.
Topics: Adult; Androstanes; Animals; Benz(a)Anthracenes; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; | 1974 |