dehydroepiandrosterone has been researched along with Atherosclerosis in 29 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Several clinical trials have indicated that dehydroepiandrosterone (DHEA) reduces coronary events associated with atherosclerosis." | 7.75 | Effect of dehydroepiandrosterone on atherosclerosis in apolipoprotein E-deficient mice. ( Kadonosono, K; Kishikawa, S; Nakamura, M; Ogihara, K; Terauchi, Y; Utsunomiya, H; Yamakawa, T, 2009) |
| "The risk for atherosclerosis is increased in postmenopausal women." | 5.37 | Protective effects of dehydroepiandrosterone on atherosclerosis in ovariectomized rabbits via alleviating inflammatory injury in endothelial cells. ( Hao, Q; Li, DJ; Wang, L; Wang, WJ; Wang, YD, 2011) |
| "Several clinical and population-based studies suggest that dehydroepiandrosterone (DHEA) and its sulphate (DHEA-S) play a protective role against atherosclerosis and coronary artery disease in human." | 5.12 | Short-term dehydroepiandrosterone treatment increases platelet cGMP production in elderly male subjects. ( Benso, A; Ghigo, E; Gigliardi, VR; Granata, R; Martina, V; Masha, A; Origlia, C, 2006) |
| "The hypothalamic-pituitary-adrenal axis activity in the aging people is characterised by an unexplained reduction of dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) secretion while ACTH and cortisol production remains relatively unchanged." | 4.84 | [Adrenopause]. ( Krysiak, R; Okopień, B; Szkróbka, W, 2008) |
| "After adjusting for age, race/ethnicity, and lifestyle factors, baseline serum estradiol (E(2)), total and bioavailable testosterone (T), dehydroepiandrosterone (DHEA) were each positively associated and sex-hormone binding globulin (SHBG) was inversely associated with risk of hypertension." | 3.78 | Endogenous sex hormones, blood pressure change, and risk of hypertension in postmenopausal women: the Multi-Ethnic Study of Atherosclerosis. ( Cook, NR; Folsom, AR; Gapstur, SM; Ouyang, P; Szklo, M; Wang, L, 2012) |
| "Several clinical trials have indicated that dehydroepiandrosterone (DHEA) reduces coronary events associated with atherosclerosis." | 3.75 | Effect of dehydroepiandrosterone on atherosclerosis in apolipoprotein E-deficient mice. ( Kadonosono, K; Kishikawa, S; Nakamura, M; Ogihara, K; Terauchi, Y; Utsunomiya, H; Yamakawa, T, 2009) |
| "Dehydroepiandrosterone (DHEA) has a protective role against atherosclerosis." | 3.74 | Dehydroepiandrosterone inhibits the TNF-alpha-induced inflammatory response in human umbilical vein endothelial cells. ( Gutiérrez, G; López-Marure, R; Mendoza, C; Montaño, LF; Montiel, A; Reyes, E; Zapata, E, 2007) |
| " Using in vitro techniques, pretreatment of human arterial endothelial cells with estradiol, testosterone, dehydroepiandrosterone and dihydrotestosterone all induced sialylation of endothelial cells and, in a dose-response manner, reduced the capture of monocytes." | 2.53 | Sex Steroids Block the Initiation of Atherosclerosis. ( Fadiel, A; Mehr, H; Naftolin, F, 2016) |
| "The risk for atherosclerosis is increased in postmenopausal women." | 1.37 | Protective effects of dehydroepiandrosterone on atherosclerosis in ovariectomized rabbits via alleviating inflammatory injury in endothelial cells. ( Hao, Q; Li, DJ; Wang, L; Wang, WJ; Wang, YD, 2011) |
| "Dehydroepiandrosterone was positively associated with IFG but not with diabetes." | 1.35 | Association of endogenous sex hormones with diabetes and impaired fasting glucose in men: multi-ethnic study of atherosclerosis. ( Colangelo, LA; Cushman, M; Dobs, AS; Gapstur, SM; Golden, SH; Kopp, P; Liu, K; Ouyang, P; Szklo, M; Vaidya, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.90) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (48.28) | 29.6817 |
| 2010's | 11 (37.93) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 1 |
| Zhou, J | 1 |
| Li, L | 1 |
| Pan, X | 1 |
| Lin, J | 1 |
| Li, C | 1 |
| Leung, WT | 1 |
| Wang, L | 3 |
| Kazzi, B | 1 |
| Ogunmoroti, O | 1 |
| Rodriguez, CP | 1 |
| Zhao, D | 3 |
| Minhas, AS | 1 |
| Osibogun, O | 1 |
| Subramanya, V | 2 |
| Allison, MA | 1 |
| Ouyang, P | 9 |
| Michos, ED | 5 |
| Meun, C | 1 |
| Franco, OH | 1 |
| Dhana, K | 1 |
| Jaspers, L | 1 |
| Muka, T | 1 |
| Louwers, Y | 1 |
| Ikram, MA | 1 |
| Fauser, BCJM | 1 |
| Kavousi, M | 1 |
| Laven, JSE | 1 |
| Mathews, L | 1 |
| Vaidya, D | 5 |
| Guallar, E | 2 |
| Yeboah, J | 1 |
| Herrington, D | 1 |
| Hays, AG | 1 |
| Budoff, MJ | 1 |
| Khazai, B | 1 |
| Golden, SH | 3 |
| Colangelo, LA | 3 |
| Swerdloff, R | 1 |
| Wang, C | 1 |
| Honoris, L | 1 |
| Gapstur, SM | 5 |
| Cushman, M | 3 |
| Li, D | 1 |
| Kopp, P | 2 |
| Liu, K | 3 |
| Dobs, A | 1 |
| Budoff, M | 1 |
| Williams, MS | 1 |
| Heckbert, SR | 1 |
| Kalyani, RR | 2 |
| Naftolin, F | 1 |
| Mehr, H | 1 |
| Fadiel, A | 1 |
| de Boer, IH | 1 |
| Lutsey, PL | 1 |
| Farag, YM | 1 |
| Siscovick, DS | 1 |
| Post, WS | 1 |
| Billups, KL | 1 |
| Krysiak, R | 2 |
| Frysz-Naglak, D | 1 |
| Okopień, B | 2 |
| Szkróbka, W | 1 |
| Li, Y | 1 |
| Xia, Z | 1 |
| Wang, M | 1 |
| Cheng, HH | 3 |
| Hu, XJ | 2 |
| Ruan, QR | 3 |
| Dobs, AS | 1 |
| Szklo, M | 2 |
| Yamakawa, T | 1 |
| Ogihara, K | 1 |
| Nakamura, M | 1 |
| Utsunomiya, H | 1 |
| Kadonosono, K | 1 |
| Kishikawa, S | 1 |
| Terauchi, Y | 1 |
| Marder, W | 1 |
| Somers, EC | 1 |
| Kaplan, MJ | 1 |
| Anderson, MR | 1 |
| Lewis, EE | 1 |
| McCune, WJ | 1 |
| Hao, Q | 1 |
| Wang, YD | 1 |
| Wang, WJ | 1 |
| Li, DJ | 1 |
| Pizza, V | 1 |
| Agresta, A | 1 |
| D'Acunto, CW | 1 |
| Festa, M | 1 |
| Capasso, A | 1 |
| Craft, LL | 1 |
| Schreiner, PJ | 2 |
| Folsom, AR | 1 |
| Cook, NR | 1 |
| MIKULASKOVA, J | 2 |
| LINET, O | 2 |
| BARTOSEK, I | 1 |
| Kaufman, JM | 1 |
| Vermeulen, A | 1 |
| Martina, V | 1 |
| Benso, A | 1 |
| Gigliardi, VR | 1 |
| Masha, A | 1 |
| Origlia, C | 1 |
| Granata, R | 1 |
| Ghigo, E | 1 |
| Gutiérrez, G | 1 |
| Mendoza, C | 1 |
| Zapata, E | 1 |
| Montiel, A | 1 |
| Reyes, E | 1 |
| Montaño, LF | 1 |
| López-Marure, R | 1 |
| Valenti, G | 1 |
| Denti, L | 1 |
| Saccò, M | 1 |
| Ceresini, G | 1 |
| Bossoni, S | 1 |
| Giustina, A | 1 |
| Maugeri, D | 1 |
| Vigna, GB | 1 |
| Fellin, R | 1 |
| Paolisso, G | 1 |
| Barbagallo, M | 1 |
| Maggio, M | 1 |
| Strollo, F | 1 |
| Bollanti, L | 1 |
| Romanelli, F | 1 |
| Latini, M | 1 |
| Nakhai Pour, HR | 1 |
| Grobbee, DE | 1 |
| Bots, ML | 1 |
| Verhaar, HJ | 1 |
| Muller, M | 1 |
| van der Schouw, YT | 1 |
| Qu, ZL | 1 |
| Zhou, Y | 1 |
| Ban, ZY | 1 |
| Wong, ND | 1 |
| Criqui, MH | 1 |
7 reviews available for dehydroepiandrosterone and Atherosclerosis
| Article | Year |
|---|---|
Effect of dehydroepiandrosterone on atherosclerosis in postmenopausal women.
Topics: Atherosclerosis; Dehydroepiandrosterone; Endothelial Cells; Estrogens; Female; Humans; Postmenopause | 2022 |
Sex Steroids Block the Initiation of Atherosclerosis.
Topics: Animals; Atherosclerosis; Cell Adhesion Molecules; Dehydroepiandrosterone; Dihydrotestosterone; Endo | 2016 |
[Current views on the role of dehydroepiandrosterone in physiology, pathology and therapy].
Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenarche; Aged; Aging; Atherosclerosis; Cardiovascular Sys | 2008 |
[Adrenopause].
Topics: Adolescent; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Aging; Androgens; Ather | 2008 |
Neuroinflammation and ageing: current theories and an overview of the data.
Topics: Aging; Alzheimer Disease; Apoptosis; Atherosclerosis; Biological Evolution; Brain; Cellular Senescen | 2011 |
The decline of androgen levels in elderly men and its clinical and therapeutic implications.
Topics: Aged; Aging; Androgens; Atherosclerosis; Clinical Trials as Topic; Coronary Disease; Dehydroepiandro | 2005 |
[Physiology of dehydroepiandrosterone and dehydroepiandrosterone sulfate and its relationship with atherosclerosis].
Topics: Animals; Atherosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hormone Replacemen | 2006 |
2 trials available for dehydroepiandrosterone and Atherosclerosis
| Article | Year |
|---|---|
Effects of prasterone (dehydroepiandrosterone) on markers of cardiovascular risk and bone turnover in premenopausal women with systemic lupus erythematosus: a pilot study.
Topics: Adjuvants, Immunologic; Adult; Atherosclerosis; Bone Density; Cholesterol, HDL; Cross-Over Studies; | 2010 |
Short-term dehydroepiandrosterone treatment increases platelet cGMP production in elderly male subjects.
Topics: Aged; Atherosclerosis; Biomarkers; Blood Chemical Analysis; Blood Platelets; Cyclic GMP; Dehydroepia | 2006 |
20 other studies available for dehydroepiandrosterone and Atherosclerosis
| Article | Year |
|---|---|
Parity History and Later Life Sex Hormone Levels in the Multi-Ethnic Study of Atherosclerosis (MESA).
Topics: Androgens; Atherosclerosis; Cardiovascular Diseases; Cross-Sectional Studies; Dehydroepiandrosterone | 2022 |
High Androgens in Postmenopausal Women and the Risk for Atherosclerosis and Cardiovascular Disease: The Rotterdam Study.
Topics: Aged; Aged, 80 and over; Androgens; Androstenedione; Atherosclerosis; Calcium; Cardiovascular Diseas | 2018 |
Endogenous Sex Hormones and Endothelial Function in Postmenopausal Women and Men: The Multi-Ethnic Study of Atherosclerosis.
Topics: Aged; Androgens; Atherosclerosis; Brachial Artery; Cross-Sectional Studies; Dehydroepiandrosterone; | 2019 |
Association of endogenous testosterone with subclinical atherosclerosis in men: the multi-ethnic study of atherosclerosis.
Topics: Aged; Aged, 80 and over; Asian; Atherosclerosis; Black or African American; Calcium; Carotid Intima- | 2016 |
Association of Serum Sex Hormones with Hemostatic Factors in Women On and Off Hormone Therapy: The Multiethnic Study of Atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; C-Reactive Protein; Cross-Sectional Stu | 2016 |
Serum vitamin D and sex hormones levels in men and women: The Multi-Ethnic Study of Atherosclerosis (MESA).
Topics: Adiposity; Aged; Atherosclerosis; Cross-Sectional Studies; Dehydroepiandrosterone; Estradiol; Ethnic | 2017 |
Dehydroepiandrosterone inhibits CD40/CD40L expression on human umbilical vein endothelial cells induced by interferon gamma.
Topics: Adjuvants, Immunologic; Atherosclerosis; Butadienes; CD40 Antigens; CD40 Ligand; Cells, Cultured; De | 2009 |
Dehydroepiandrosterone anti-atherogenesis effect is not via its conversion to estrogen.
Topics: Animals; Arteries; Atherosclerosis; Cells, Cultured; Chemokine CCL2; Dehydroepiandrosterone; Diet; E | 2009 |
Association of endogenous sex hormones with diabetes and impaired fasting glucose in men: multi-ethnic study of atherosclerosis.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Body Mass Index; Cohort Studies; Dehydroepiandrosterone; D | 2009 |
Effect of dehydroepiandrosterone on atherosclerosis in apolipoprotein E-deficient mice.
Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Chemokine CCL2; Cholesterol; Dehydroep | 2009 |
Protective effects of dehydroepiandrosterone on atherosclerosis in ovariectomized rabbits via alleviating inflammatory injury in endothelial cells.
Topics: Animals; Atherosclerosis; Chemokine CCL2; Dehydroepiandrosterone; E-Selectin; Endothelial Cells; Fem | 2011 |
Association of sex hormones and sex hormone-binding globulin with depressive symptoms in postmenopausal women: the Multiethnic Study of Atherosclerosis.
Topics: Aged; Aged, 80 and over; Asian; Atherosclerosis; Black People; Dehydroepiandrosterone; Depression; E | 2012 |
Endogenous sex hormones, blood pressure change, and risk of hypertension in postmenopausal women: the Multi-Ethnic Study of Atherosclerosis.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Blood Pressure; Dehydroepiandrosterone; Estradiol; Female; | 2012 |
[FURTHER HISTOCHEMICAL STUDIES ON THE EFFECT OF DEHYDROEPIANDROSTERONE ON EXPERIMENTAL ATHEROMATOSIS IN RABBITS].
Topics: Animals; Arteriosclerosis; Atherosclerosis; Dehydroepiandrosterone; Histocytochemistry; Lagomorpha; | 1964 |
[Experiments on alteration of atheromatosis in rabbits by dehydroepiandrosterone].
Topics: Androgens; Animals; Atherosclerosis; Dehydroepiandrosterone; Lagomorpha; Rabbits | 1962 |
Dehydroepiandrosterone inhibits the TNF-alpha-induced inflammatory response in human umbilical vein endothelial cells.
Topics: Adjuvants, Immunologic; Atherosclerosis; Cell Adhesion; Chemokine CCL2; Dehydroepiandrosterone; E-Se | 2007 |
Consensus Document on substitution therapy with DHEA in the elderly.
Topics: Adult; Aged; Aged, 80 and over; Aging; Atherosclerosis; Bone Diseases, Metabolic; Cognition Disorder | 2006 |
Circulating sex hormone levels and aortic stiffness in men.
Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Cross-Sectional Studies; Dehydroepiandrosterone; Ge | 2007 |
[Study of dehydroepiandrosterone retarding atherosclerosis of high cholesterol-fed rabbits].
Topics: Animals; Aorta; Atherosclerosis; Chemokine CCL2; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL | 2007 |
Sex hormones, sex hormone binding globulin, and abdominal aortic calcification in women and men in the multi-ethnic study of atherosclerosis (MESA).
Topics: Aged; Aged, 80 and over; Aorta, Abdominal; Atherosclerosis; Cardiovascular Diseases; Cohort Studies; | 2008 |