dehydroepiandrosterone has been researched along with Arteriosclerosis in 32 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the correlation between dehydroepiandrosterone and arteriosclerosis in premenopausal and postmenopausal women." | 7.74 | [Relationship between dehydroepiandrosterone and arteriosclerosis in premenopausal and postmenopausal women]. ( Jian, ZW; Ruan, YJ; Wu, SZ, 2008) |
| " The author's own findings and the data available in the literature indicate that the androgens dehydroepiandrosterone and dehydroepiandrosterone sulfate that are secreted in the reticular area play an important role in ensuring the body's full stable adaptation to stress and simultaneously preventing stress-associated abnormalities, such as atherosclerosis, diabetes, immunodefficiency, hypertension, allergies, and cancer." | 4.80 | [Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease]. ( Obut, TA, 1998) |
| "To investigate the correlation between dehydroepiandrosterone and arteriosclerosis in premenopausal and postmenopausal women." | 3.74 | [Relationship between dehydroepiandrosterone and arteriosclerosis in premenopausal and postmenopausal women]. ( Jian, ZW; Ruan, YJ; Wu, SZ, 2008) |
| " We examined the possible associations of sex hormone-binding globulin, total and free testosterone, estradiol, and dehydroepiandrosterone sulfate to Lp(a) concentrations in men in two population-based studies (San Antonio Heart Study [n = 178] and a Finnish study on the association between insulin resistance and atherosclerosis [n = 87])." | 3.69 | Lack of association between sex hormones and Lp(a) concentrations in American and Finnish men. ( Gruber, KK; Haffner, SM; Laakso, M; Mykkanen, L; Rainwater, DL, 1994) |
| "To evaluate the role of adrenal androgens in the development of arteriosclerosis, serum dehydroepiandrosterone sulfate (DHEAS), dehydroepiandrosterone (DHEA), aortic calcification and pulse wave velocity (PWV) were measured in 69 males and 119 females without overt cardiovascular disease." | 3.68 | Role of adrenal androgens in the development of arteriosclerosis as judged by pulse wave velocity and calcification of the aorta. ( Aizawa, T; Hiramatsu, K; Ishihara, F; Matsuo, K; Niwa, A; Shigematsu, S; Takasu, N; Yamada, T, 1992) |
| "Type 2 diabetes mellitus is increasing globally and is an established risk factor for the development of atherosclerotic vascular disease." | 2.43 | Androgens, insulin resistance and vascular disease in men. ( Channer, KS; Jones, TH; Kapoor, D; Malkin, CJ, 2005) |
| "We advance the hypothesis that hyperinsulinemia promotes macrovascular disease in part by reducing serum DHEA and DHEA-sulfate levels and illustrate how this may be the case in two clinical conditions characterized by hyperinsulinemic insulin resistance: aging and obesity." | 2.38 | Dehydroepiandrosterone: the "missing link" between hyperinsulinemia and atherosclerosis? ( Blackard, WG; Clore, JN; Nestler, JE, 1992) |
| "In animals with experimental hyperlipidemia, DHEA acts protectively, decreasing degenerative changes in internal organs caused by an atherogenic diet." | 1.30 | The influence of dehydroepiandrosterone on histology of selected organs in rabbits on an atherogenic diet. ( Bednarek-Tupikowska, G; Bohdanowicz-Pawlak, A; Kosowska, B; Kuryszko, J; Milewicz, A, 1999) |
| "Dehydroepiandrosterone (DHEA) is an endogenous steroid that blocks carcinogenesis, retards aging, and exerts antiproliferative properties." | 1.27 | Reduction of atherosclerosis by administration of dehydroepiandrosterone. A study in the hypercholesterolemic New Zealand white rabbit with aortic intimal injury. ( Bush, DE; Gordon, GB; Weisman, HF, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (37.50) | 18.7374 |
| 1990's | 11 (34.38) | 18.2507 |
| 2000's | 9 (28.13) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jian, ZW | 1 |
| Wu, SZ | 1 |
| Ruan, YJ | 1 |
| van den Beld, AW | 1 |
| Bots, ML | 1 |
| Janssen, JA | 1 |
| Pols, HA | 1 |
| Lamberts, SW | 1 |
| Grobbee, DE | 1 |
| DONNES, AV | 1 |
| PERALTA, EL | 1 |
| GONZALEZ, EE | 1 |
| MIKULASKOVA, J | 1 |
| LINET, O | 1 |
| Ng, MK | 1 |
| Nakhla, S | 1 |
| Baoutina, A | 1 |
| Jessup, W | 1 |
| Handelsman, DJ | 1 |
| Celermajer, DS | 1 |
| Kapoor, D | 1 |
| Malkin, CJ | 1 |
| Channer, KS | 1 |
| Jones, TH | 1 |
| Haffner, SM | 1 |
| Mykkanen, L | 1 |
| Gruber, KK | 1 |
| Rainwater, DL | 1 |
| Laakso, M | 1 |
| Svacina, S | 2 |
| Sonka, J | 3 |
| Haas, T | 1 |
| Taniguchi, S | 1 |
| Yanase, T | 1 |
| Kobayashi, K | 1 |
| Takayanagi, R | 1 |
| Nawata, H | 1 |
| Hashimoto, S | 1 |
| Katou, M | 1 |
| Dong, Y | 1 |
| Murakami, K | 1 |
| Terada, S | 1 |
| Inoue, M | 1 |
| Obut, TA | 1 |
| Alexandersen, P | 1 |
| Haarbo, J | 1 |
| Byrjalsen, I | 1 |
| Lawaetz, H | 1 |
| Christiansen, C | 1 |
| Nippoldt, TB | 1 |
| Nair, KS | 1 |
| Bednarek-Tupikowska, G | 1 |
| Kuryszko, J | 1 |
| Kosowska, B | 1 |
| Bohdanowicz-Pawlak, A | 1 |
| Milewicz, A | 1 |
| Hayashi, T | 1 |
| Esaki, T | 1 |
| Muto, E | 1 |
| Kano, H | 1 |
| Asai, Y | 1 |
| Thakur, NK | 1 |
| Sumi, D | 1 |
| Jayachandran, M | 1 |
| Iguchi, A | 1 |
| Nedĕlníková, K | 1 |
| Matoulek, M | 1 |
| Zdrojewicz, Z | 1 |
| Kesik, S | 1 |
| Vatalas, IA | 1 |
| Dionyssiou-Asteriou, A | 1 |
| Anisimov, VE | 1 |
| Nestler, JE | 1 |
| Clore, JN | 1 |
| Blackard, WG | 1 |
| Ishihara, F | 1 |
| Hiramatsu, K | 1 |
| Shigematsu, S | 1 |
| Aizawa, T | 1 |
| Niwa, A | 1 |
| Takasu, N | 1 |
| Yamada, T | 1 |
| Matsuo, K | 1 |
| Nafziger, AN | 1 |
| Herrington, DM | 1 |
| Bush, TL | 1 |
| Gordon, GB | 1 |
| Bush, DE | 1 |
| Weisman, HF | 1 |
| La Paglia, S | 1 |
| Andreani, G | 1 |
| Sznajderman, M | 1 |
| Miasnikov, LA | 2 |
| Miasnikova, NV | 1 |
| Vinogradova, DA | 2 |
| Rukhmanov, AA | 1 |
| Shimamoto, M | 1 |
| Takeda, R | 1 |
| Noto, Y | 1 |
| Gregorovà, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Incidence of Diabetes and Cardiovascular Disease in Mexican Americans[NCT00005205] | 0 participants | Observational | 1987-08-31 | Completed | |||
| Biological Effects of DHEA in the Elderly[NCT00111930] | 144 participants | Interventional | 2000-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for dehydroepiandrosterone and Arteriosclerosis
| Article | Year |
|---|---|
Androgens, insulin resistance and vascular disease in men.
Topics: Aged; Aging; Arteriosclerosis; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Humans; Insulin Re | 2005 |
[Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease].
Topics: Adjuvants, Immunologic; Animals; Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 1998 |
Is there a case for DHEA replacement?
Topics: Adult; Aged; Aging; Alzheimer Disease; Animals; Arteriosclerosis; Bone Remodeling; Carbohydrate Meta | 1998 |
[Dehydroepiandrosterone (DHEA)--youth hormone?].
Topics: Aging; Arteriosclerosis; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes | 2001 |
[Hyperuricemia and arteriosclerosis].
Topics: Adult; Arteriosclerosis; Coronary Disease; Dehydroepiandrosterone; Female; Gout; Humans; Hyperlipide | 1978 |
Dehydroepiandrosterone: the "missing link" between hyperinsulinemia and atherosclerosis?
Topics: Aging; Animals; Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hy | 1992 |
Dehydroepiandrosterone and dehydroepiandrosterone sulfate: their relation to cardiovascular disease.
Topics: Adolescent; Adult; Aged; Aging; Animals; Arteriosclerosis; Biomarkers; Cardiovascular Diseases; Case | 1991 |
[Relationship between sex hormones, atherosclerosis and Takayasu's disease (arteriosclerocirrhosis, Nasu): sex hormones and arteriosclerosis].
Topics: Adult; Animals; Aortic Arch Syndromes; Arteriosclerosis; Cholesterol; Coronary Vessels; Dehydroepian | 1972 |
[Adrenocortical hormones and arteriosclerosis].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Androgens; Arteriosclerosis | 1972 |
23 other studies available for dehydroepiandrosterone and Arteriosclerosis
| Article | Year |
|---|---|
[Relationship between dehydroepiandrosterone and arteriosclerosis in premenopausal and postmenopausal women].
Topics: Adult; Arteriosclerosis; Carotid Artery Diseases; Dehydroepiandrosterone; Female; Humans; Lipids; Mi | 2008 |
Endogenous hormones and carotid atherosclerosis in elderly men.
Topics: Aged; Aged, 80 and over; Aging; Arteriosclerosis; Carotid Artery Diseases; Case-Control Studies; Deh | 2003 |
[Combination of an insoluble procaine salt and dehydroisoandrosterone in the treatment of arteriosclerosis and post-thrombotic cerebral syndrome].
Topics: Aged; Aged, 80 and over; Androgens; Arteriosclerosis; Dehydroepiandrosterone; Hemiplegia; Humans; In | 1960 |
[FURTHER HISTOCHEMICAL STUDIES ON THE EFFECT OF DEHYDROEPIANDROSTERONE ON EXPERIMENTAL ATHEROMATOSIS IN RABBITS].
Topics: Animals; Arteriosclerosis; Atherosclerosis; Dehydroepiandrosterone; Histocytochemistry; Lagomorpha; | 1964 |
Dehydroepiandrosterone, an adrenal androgen, increases human foam cell formation: a potentially pro-atherogenic effect.
Topics: Acyl Coenzyme A; Arteriosclerosis; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Choleste | 2003 |
Over-the-counter supplement may raise heart attack.
Topics: Arteriosclerosis; Dehydroepiandrosterone; Dietary Supplements; Foam Cells; Humans; Male | 2004 |
Lack of association between sex hormones and Lp(a) concentrations in American and Finnish men.
Topics: Adult; Arteriosclerosis; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sul | 1994 |
Dehydroepiandrosterone and insulinaemia.
Topics: Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus; Humans; | 1995 |
Dehydroepiandrosterone markedly inhibits the accumulation of cholesteryl ester in mouse macrophage J774-1 cells.
Topics: Androstenes; Animals; Arteriosclerosis; Bucladesine; Cell Line; Cholesterol; Cholesterol Esters; Deh | 1996 |
Effects of hormone replacement therapy on serum amyloid P component in postmenopausal women.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arteriosclerosis; Biomarkers; | 1997 |
Natural androgens inhibit male atherosclerosis: a study in castrated, cholesterol-fed rabbits.
Topics: Adrenal Glands; Animals; Aorta; Aortic Diseases; Arteriosclerosis; Cholesterol, Dietary; Cholesterol | 1999 |
The influence of dehydroepiandrosterone on histology of selected organs in rabbits on an atherogenic diet.
Topics: Adrenal Glands; Animals; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dehydroe | 1999 |
Dehydroepiandrosterone retards atherosclerosis formation through its conversion to estrogen: the possible role of nitric oxide.
Topics: Acetylcholine; Adjuvants, Immunologic; Animals; Aorta, Thoracic; Aromatase; Arteriosclerosis; Calcim | 2000 |
[Metabolic and hormonal links in obese individuals with and without symptoms of syndrome X].
Topics: Arteriosclerosis; Dehydroepiandrosterone; Diabetes Mellitus; Humans; Insulin Resistance; Lipids; Obe | 2000 |
Adrenal C19 steroids and serum lipoprotein levels in healthy men.
Topics: Adult; Androstenedione; Apolipoprotein A-I; Apolipoproteins; Apolipoproteins B; Arteriosclerosis; Bo | 2001 |
Role of adrenal androgens in the development of arteriosclerosis as judged by pulse wave velocity and calcification of the aorta.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aged, 80 and over; Androgens; Aorta, Thoracic; Arterioscler | 1992 |
Reduction of atherosclerosis by administration of dehydroepiandrosterone. A study in the hypercholesterolemic New Zealand white rabbit with aortic intimal injury.
Topics: Animals; Aortic Diseases; Arteriosclerosis; Body Weight; Cholesterol; Dehydroepiandrosterone; Dehydr | 1988 |
[Remarks on the behavior of the lipoproteic pattern and of hematic coagulation after administration of dehydroisoandrosterone].
Topics: Adolescent; Adult; Arteriosclerosis; Blood Coagulation; Blood Proteins; Dehydroepiandrosterone; Fema | 1967 |
Urinary excretion of neutral 17-ketosteroids and their fractions in men with coronary heart disease.
Topics: 17-Ketosteroids; Adult; Age Factors; Androsterone; Arteriosclerosis; Coronary Disease; Dehydroepiand | 1968 |
[Status of metabolism of cortisone and androgens in patients with atherosclerosis].
Topics: 17-Ketosteroids; Adrenal Glands; Adult; Androgens; Androsterone; Arteriosclerosis; Chromatography, T | 1970 |
[Estrogens and androgens in dyshormonal cardiopathy and coronary atherosclerosis in women].
Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Arteriosclerosis; Chromatography, Thin Layer; Coron | 1971 |
[The functional state of the adrenal cortex and various aspects of the pathogenesis of cerebral circulatory disorders in hypertension and cerebral atherosclerosis].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Aged; Arteriosc | 1972 |
The role of DHA in the pathogenesis of obesity and its metabolic complications.
Topics: Amino Acids; Arteriosclerosis; Cholesterol; Dehydroepiandrosterone; Diabetes Mellitus; Fatty Acids; | 1969 |