dehydroepiandrosterone has been researched along with Ambiguous Genitalia in 64 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 24 years old male with pseudohermaphroditism due to a deficiency in 17-ketosteroid reductase activity is described." | 1.27 | 17-ketosteroid reductase deficiency in an adult patient without gynaecomastia but with female psychosexual orientation. ( Audí, L; Esmatjes, E; Martinez de Osaba, MJ; Martinez-Mora, J; Millán, M; Peig, M; Viguera, J; Vilardell, E, 1983) |
| "The male pseudohermaphroditism resulted from deficient testosterone synthesis due to deficiency of 17 alpha-hydroxylase and 17,20 desmolase." | 1.27 | Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia. ( Gautier, T; Imperato-McGinley, J; Peterson, RE; Shackleton, C, 1985) |
| "Three patients with male pseudohermaphroditism due to 17,20-desmolase deficiency were studied at a pubertal age." | 1.26 | Two types of male pseudohermaphroditism due to 17, 20-desmolase deficiency. ( Prader, A; Werder, EA; Zachmann, M, 1982) |
| "In two siblings with male pseudohermaphroditism (ambiguous external genitalia, XY karyotype) and apparently normal glucocorticoid function, plasma concentrations of 10 progestagens or androgens measured by specific RIAs were found to be abnormal under either basal or dynamic conditions." | 1.26 | Familial male pseudohermaphroditism due to 17-20-desmolase deficiency. I. In vivo endocrine studies. ( de Peretti, E; Forest, MG; Lecornu, M, 1980) |
| "In 22 children with male pseudohermaphroditism, plasma concentrations of testosterone and dehydroandrosterone sulfate were measured before and after HCG stimulation." | 1.25 | Children with male pseudohermaphroditism: endocrine and metabolic studies. ( Bertrand, J; De Peretti, E; Frederich, A; Saez, JM, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (89.06) | 18.7374 |
| 1990's | 4 (6.25) | 18.2507 |
| 2000's | 1 (1.56) | 29.6817 |
| 2010's | 2 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johannsen, TH | 1 |
| Main, KM | 1 |
| Ljubicic, ML | 1 |
| Jensen, TK | 1 |
| Andersen, HR | 1 |
| Andersen, MS | 1 |
| Petersen, JH | 1 |
| Andersson, AM | 1 |
| Juul, A | 1 |
| Auchus, RJ | 1 |
| Chang, AY | 1 |
| Rösler, A | 1 |
| BIGOZZI, U | 1 |
| BORGHI, A | 1 |
| KASE, N | 1 |
| MORRIS, JM | 1 |
| JOSSO, N | 1 |
| DE GROUCHY, J | 1 |
| AUVERT, J | 1 |
| NEZELOF, C | 1 |
| JAYLE, MF | 1 |
| MOULLEC, J | 1 |
| FREZAL, J | 1 |
| DE CASAUBON, A | 1 |
| LAMY, M | 1 |
| NEHER, R | 1 |
| KAHNT, FW | 1 |
| ROVERSI, GD | 1 |
| BOMPIANI, A | 1 |
| ten Kate-Booij, MJ | 1 |
| Cobbaert, C | 1 |
| Koper, JW | 1 |
| de Jong, FH | 1 |
| Zachmann, M | 3 |
| Werder, EA | 1 |
| Prader, A | 1 |
| Millán, M | 1 |
| Audí, L | 1 |
| Martinez-Mora, J | 1 |
| Martinez de Osaba, MJ | 1 |
| Viguera, J | 1 |
| Esmatjes, E | 1 |
| Peig, M | 1 |
| Vilardell, E | 1 |
| Forest, MG | 1 |
| Lecornu, M | 1 |
| de Peretti, E | 5 |
| Campo, S | 2 |
| Moteagudo, C | 1 |
| Nicolau, G | 2 |
| Pellizzari, E | 1 |
| Belgorosky, A | 1 |
| Stivel, M | 2 |
| Rivarola, M | 2 |
| Pittaway, DE | 2 |
| Andersen, RN | 2 |
| Givens, JR | 2 |
| Stanczyk, FZ | 2 |
| Goebelsmann, U | 3 |
| Nakamura, RM | 1 |
| Hall, TD | 1 |
| Paul, WL | 1 |
| Gallegos, AJ | 1 |
| Guizar, E | 1 |
| Armendares, S | 1 |
| Cortés-Gallegos, V | 1 |
| Cervantes, C | 1 |
| Bedolla, N | 1 |
| Parra, A | 1 |
| Booth, WD | 1 |
| Polge, C | 1 |
| Schaison, G | 1 |
| Sitruk, LR | 1 |
| Savage, MO | 1 |
| Chaussain, JL | 1 |
| Evain, D | 1 |
| Roger, M | 1 |
| Canlorbe, P | 1 |
| Job, JC | 2 |
| Vancrombreucq, T | 1 |
| Govaerts, M | 1 |
| Preumont, P | 1 |
| Schwers, J | 1 |
| Monteagudo, C | 1 |
| Cadillon, E | 1 |
| Bertrand, J | 5 |
| Davajan, V | 1 |
| Israel, R | 1 |
| Mestman, JH | 1 |
| Mishell, DR | 1 |
| Augarten, A | 1 |
| Pariente, C | 1 |
| Gazit, E | 1 |
| Chayen, R | 1 |
| Goldfarb, H | 1 |
| Sack, J | 1 |
| Shozu, M | 1 |
| Akasofu, K | 1 |
| Harada, T | 1 |
| Kubota, Y | 1 |
| Imperato-McGinley, J | 2 |
| Miller, M | 1 |
| Wilson, JD | 2 |
| Peterson, RE | 2 |
| Shackleton, C | 2 |
| Gajdusek, DC | 1 |
| Nahoul, K | 2 |
| Perrin, C | 1 |
| Leymarie, P | 1 |
| Taketo-Hosotani, T | 1 |
| Nishioka, Y | 1 |
| Nagamine, CM | 1 |
| Villalpando, I | 1 |
| Merchant-Larios, H | 1 |
| Gautier, T | 1 |
| Wit, JM | 1 |
| van Hooff, CO | 1 |
| Thijssen, JH | 1 |
| Van den Brande, JL | 1 |
| Bercovici, JP | 1 |
| Maudelonde, T | 1 |
| Tater, D | 1 |
| Scholler, R | 1 |
| David, RR | 1 |
| Wiener, M | 1 |
| Ross, L | 1 |
| Landau, RL | 1 |
| Pion, RJ | 1 |
| Dignam, WJ | 1 |
| Lamb, EJ | 1 |
| Moore, JG | 1 |
| Frankland, MV | 1 |
| Simmer, HH | 1 |
| Philip, J | 1 |
| Trolle, D | 1 |
| Rivera, R | 1 |
| Dorfman, RI | 1 |
| Forchielli, E | 1 |
| Rice, BF | 1 |
| Cleveland, WW | 1 |
| Sandberg, DH | 1 |
| Ahmad, N | 1 |
| Politano, VT | 1 |
| Savard, K | 1 |
| Rivarola, MA | 1 |
| Saez, JM | 5 |
| Meyer, WJ | 1 |
| Kenny, FM | 3 |
| Migeon, CJ | 1 |
| Pierrepoint, CG | 1 |
| Galley, JM | 1 |
| Griffiths, K | 1 |
| Grant, JK | 1 |
| Forleo, R | 1 |
| Ingiulla, W | 1 |
| Stárka, L | 2 |
| Janata, J | 2 |
| Charreau, E | 1 |
| Villee, CA | 1 |
| Green, OC | 2 |
| Miller, RR | 1 |
| Garcia, O | 1 |
| Hamwi, GJ | 1 |
| Pérez-Palacios, G | 1 |
| Lamont, KG | 1 |
| Pérez, AE | 1 |
| Jaffe, RB | 1 |
| Pierce, GB | 1 |
| Rappaport, R | 1 |
| Zimprich, H | 1 |
| Morera, AM | 2 |
| David, M | 1 |
| Frédérich, A | 2 |
| Sachsse, W | 2 |
| Gilfrich, HJ | 2 |
| Overzier, C | 2 |
| Menzel, P | 1 |
| Jonas, A | 1 |
| Vanha-Perttula, T | 1 |
| Schneider, G | 1 |
| Bardin, CW | 1 |
| Stanley, AJ | 1 |
| Gumbreck, LG | 1 |
| Allison, JE | 1 |
| Reynolds, JW | 1 |
| Kelch, RP | 1 |
| Jenner, MR | 1 |
| Weinstein, R | 1 |
| Kaplan, SL | 1 |
| Grumbach, MM | 1 |
| Mizutani, S | 1 |
| Sonoda, T | 1 |
| Furuyama, J | 1 |
| Takemura, M | 1 |
| Matsumoto, K | 1 |
| Goldstein, JL | 1 |
| Parks, GA | 1 |
| Dumars, KW | 1 |
| Limbeck, GA | 1 |
| Quinlivan, WL | 1 |
| New, MI | 1 |
| Goldman, AS | 1 |
| Klingele, DA | 1 |
| Wiser, WL | 1 |
| Summitt, RL | 1 |
| Kerber, IJ | 1 |
| Fish, SA | 1 |
| Rosenfield, RL | 1 |
| Barmach de Niepomniszsze, A | 1 |
| Genel, M | 1 |
| Gower, DB | 1 |
| Bicknell, DC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Turner Syndrome Minipuberty Study A Prospective, Descriptive Cohortstudy[NCT04189406] | 30 participants (Anticipated) | Observational | 2020-02-01 | Recruiting | |||
| Pharmacokinetics of a Novel Oral Testosterone Undecanoate Formulation With Concomitant Inhibition of 5alpha-Reductase by Finasteride[NCT00842751] | Phase 2 | 11 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 10 Days in Normal Men With Experimental Hypogonadism[NCT01167829] | Phase 1 | 14 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Area under the curve of serum testosterone Pharmacokinetic measures time-weighted mean concentration calculated as area under the concentration curve (AUC) divided by time from initiation of dosing for the morning dose and corrected for differences in baseline hormone concentration. (NCT00842751)
Timeframe: 0,1,2,4,8,and 12-hour post dose
| Intervention | ng*hr/dL (Geometric Mean) |
|---|---|
| Acyline +Testosterone Undecanoate + Placebo | 471 |
| Acyline +Testosterone Undecanoate + 0.5mg Finasteride | 444 |
| Acyline +Testosterone Undecanoate + 1mg Finasteride | 543 |
Area under the curve of serum dihydrotestosterone (NCT00842751)
Timeframe: 0,1,2,4,8,and 12-hour post dose
| Intervention | ng*hr/dL (Geometric Mean) |
|---|---|
| Acyline +Testosterone Undecanoate + Placebo | 154 |
| Acyline + Testosterone Undecanoate + 0.5mg Finasteride | 118 |
| Acyline + Testosterone Undecanoate + 1mg Finasteride | 125 |
Area under the curve of serum estradiol (NCT00842751)
Timeframe: 0,1,2,4,8,and 12-hour post dose
| Intervention | ng*hr/dL (Geometric Mean) |
|---|---|
| Acyline +Testosterone Undecanoate + Placebo | 7.9 |
| Acyline + Testosterone Undecanoate + 0.5mg Finasteride | 6.5 |
| Acyline +Testosterone Undecanoate + 1mg Finasteride | 7.2 |
Free T normal range 4.7-18 ng/dL (NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1-2 | Day 9-10 | |
| 300 mg Oral Testosterone | 24 | 21 |
Free T normal range 4.7-18 ng/dL (NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1-2 | Day 9-10 | |
| 300 mg Oral Testosterone | 8.7 | 8.3 |
(NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1 | Day 9 | |
| 300 mg Oral Testosterone | 233 | 142 |
(NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1 | Day 9 | |
| 300 mg Oral Testosterone | 14 | 9 |
(NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1 | Day 9 | |
| 300 mg Oral Testosterone | 31 | 22 |
initial pharmacokinetics [PK] (day 1) of oral testosterone dosed 3 times daily and the PK after 9 days of treatment (NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1 | Day 9 | |
| Acyline and 300 mg Oral Testosterone | 924 | 741 |
(NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1 | Day 9 | |
| Acyline and 300 mg Oral Testosterone | 96 | 69 |
(NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1 | Day 9 | |
| 300 mg Oral Testosterone | 11 | 7 |
(NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1 | Day 9 | |
| 300 mg Oral Testosterone | 27 | 19 |
initial 24-hour pharmacokinetics (PK) of oral testosterone dosed 3 times daily and post 24-hour PK after 9 days of treatment (NCT01167829)
Timeframe: baseline & day 9
| Intervention | ng/dL (Geometric Mean) | |
|---|---|---|
| Day 1 | Day 9 | |
| Acyine and 300 mg Oral Testosterone | 378 | 315 |
2 reviews available for dehydroepiandrosterone and Ambiguous Genitalia
| Article | Year |
|---|---|
46,XX DSD: the masculinised female.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; An | 2010 |
Steroid 17β-hydroxysteroid dehydrogenase deficiency in man: an inherited form of male pseudohermaphroditism.
Topics: 17-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Androstenedione; Arabs; Child; Dehydroepiandros | 1992 |
62 other studies available for dehydroepiandrosterone and Ambiguous Genitalia
| Article | Year |
|---|---|
Sex Differences in Reproductive Hormones During Mini-Puberty in Infants With Normal and Disordered Sex Development.
Topics: Androstenedione; Anti-Mullerian Hormone; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepi | 2018 |
[Hypersecretion of dehydroisoandrosterone and related compounds in males with symptoms of intersexuality].
Topics: Androgens; Biological Assay; Dehydroepiandrosterone; Disorders of Sex Development; Humans; Male; Med | 1957 |
STEROID SYNTHESIS IN THE CRYPTORCHID TESTES OF THREE CASES OF THE "TESTICULAR FEMINIZATION" SYNDROME.
Topics: Androgen-Insensitivity Syndrome; Androgens; Cryptorchidism; Dehydroepiandrosterone; Disorders of Sex | 1965 |
TRUE HERMAPHRODITISM WITH XX-XY MOSAICISM, PROBABLY DUE TO DOUBLE FERTILIZATION OF THE OVUM.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Blood Group Antigens; Chromosome Aberrations; Chromosome | 1965 |
STEROID TRANSFORMATIONS IN VITRO BY TESTICULAR TISSUE FROM TWO CASES OF TESTICULAR FEMINISATION.
Topics: 17-alpha-Hydroxypregnenolone; Androgen-Insensitivity Syndrome; Androgens; Chromatography; Cryptorchi | 1965 |
Deficiency of 17,20-lyase causing giant ovarian cysts in a girl and a female phenotype in her 46,XY sister: case report.
Topics: 17-alpha-Hydroxyprogesterone; Abdominal Pain; Adolescent; Alleles; Androstenedione; Dehydroepiandros | 2004 |
Two types of male pseudohermaphroditism due to 17, 20-desmolase deficiency.
Topics: Aldehyde-Lyases; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Disorders of Sex D | 1982 |
17-ketosteroid reductase deficiency in an adult patient without gynaecomastia but with female psychosexual orientation.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Androstenedione; Castration; Dehydroepiandrosterone; Disord | 1983 |
Familial male pseudohermaphroditism due to 17-20-desmolase deficiency. I. In vivo endocrine studies.
Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldehyde-Lyases; Androstenedione; Child; | 1980 |
Testicular function in prepubertal male pseudohermaphroditism.
Topics: Adolescent; Adrenocorticotropic Hormone; Androstenedione; Child; Child, Preschool; Chorionic Gonadot | 1981 |
Deficient 17 beta-hydroxysteroid oxidoreductase activity in testes from a male pseudohermaphrodite.
Topics: Androstenedione; Dehydroepiandrosterone; Disorders of Sex Development; Hydroxysteroid Dehydrogenases | 1976 |
Further in vitro steroid metabolic studies of testicular 17beta-reduction deficiency.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Androstenediol; Androstenedione; Dehydroepiandrosterone; Di | 1978 |
In vitro steroid metabolic studies in testicular 17 beta-reduction deficiency.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Estrone; Hu | 1975 |
Familial true hermaphorodism in three siblings: plasma hormonal profile and in vitro steroid biosynthesis in gonadal structures.
Topics: Adolescent; Androstenedione; Child; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; | 1976 |
The occurrence of C19 steroids in testicular tissue and submaxillary glands of intersex pigs in relation to morphological characteristics.
Topics: Androstenediols; Androstenes; Animals; Dehydroepiandrosterone; Disorders of Sex Development; Female; | 1976 |
Male pseudohermaphroditism due to testicular 17-ketosteroid reductase deficiency.
Topics: 17-Ketosteroids; Androstane-3,17-diol; Androstenedione; Blood Proteins; Child; Dehydroepiandrosteron | 1976 |
Endocrine studies in male pseudohermaphroditism in childhood and adolescence.
Topics: Adolescent; Adult; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dihydrotestoste | 1978 |
Steroid metabolism in vitro by gonadal tissue from a true hermaphrodite.
Topics: Dehydroepiandrosterone; Disorders of Sex Development; Female; Gonads; Humans; Hydroxyprogesterones; | 1979 |
Testicular function in post pubertal male pseudohermaphroditism.
Topics: Adolescent; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Disorder | 1979 |
[In vitro studies of testicular biosynthesis in 4 cases of male pseudohermaphrodism (MPH) due to testicular 17 ketoreductase defect (author's transl)].
Topics: 17-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Androstenediols; Androstenedione; Dehydroepiand | 1979 |
Male pseudohermaphroditism consistent with 17,20-desmolase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Dehydroepian | 1976 |
Ambiguous genitalia due to partial activity of cytochromes P450c17 and P450c21.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androstenedione; Chorionic Gonadotrop | 1992 |
A new cause of female pseudohermaphroditism: placental aromatase deficiency.
Topics: Adult; Androgens; Aromatase; Dehydroepiandrosterone; Disorders of Sex Development; Estrogens; Female | 1991 |
A cluster of male pseudohermaphrodites with 5 alpha-reductase deficiency in Papua New Guinea.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrostero | 1991 |
[Elevated levels of plasma 4-ene steroids in a case of congenital deficiency of 3 beta-hydroxysteroid dehydrogenase].
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Androst | 1989 |
Development and fertility of ovaries in the B6.YDOM sex-reversed female mouse.
Topics: Animals; Crosses, Genetic; Dehydroepiandrosterone; Disorders of Sex Development; Estrus; Female; Fer | 1989 |
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone | 1985 |
In vivo and in vitro studies in a 46, XY phenotypically female infant with 17-ketosteroid reductase deficiency.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Chori | 1988 |
Plasma androgens during the luteal phase in a case of true hermaphroditism with bilateral ovotestis.
Topics: Adolescent; Androgens; Androstenedione; Cosyntropin; Dehydroepiandrosterone; Dexamethasone; Disorder | 1985 |
Steroid metabolism in the syndrome of testicular feminization.
Topics: 17-Ketosteroids; Chemistry Techniques, Analytical; Chorionic Gonadotropin; Chromatography; Dehydroep | 1965 |
Testicular feminization.
Topics: Adolescent; Adult; Androgens; Castration; Chorionic Gonadotropin; Chromosomes; Dehydroepiandrosteron | 1965 |
Familial male hermaphroditism with delayed and partial masculinization.
Topics: 17-Ketosteroids; Adolescent; Androsterone; Castration; Child; Child, Preschool; Chromosomes; Dehydro | 1965 |
A modified method for the analysis of urinary 17-ketosteroids, pregnanediol and pregnanetriol by gas liquid chromatography in normal subjects and subjects with various endocrine disorders.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Cushing Syndrom | 1967 |
Steroid hormone formation by testes of a male pseudohermaphrodite.
Topics: Adult; Androgens; Androsterone; Carbon Isotopes; Chorionic Gonadotropin; Chromatography, Gas; Chroma | 1967 |
Studies of androgens in the syndrome of male pseudohermaphroditism with testicular feminization.
Topics: Adolescent; Adult; Androgens; Androsterone; Carbon Isotopes; Child; Dehydroepiandrosterone; Disorder | 1967 |
Steroid metabolism of a Sertoli cell tumour of the testis of a dog with feminization and alopecia and of the normal canine testis.
Topics: Alopecia; Animals; Chromatography, Thin Layer; Dehydroepiandrosterone; Disorders of Sex Development; | 1967 |
A time study of steroid transformations 'in vitro' in the testis of a patient with the feminine type of male pseudohermaphroditism.
Topics: Biotransformation; Carbon Isotopes; Chemical Phenomena; Chemistry; Dehydroepiandrosterone; Disorders | 1967 |
[Steroid characteristics of the syndrome of testicular feminization].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Dehydroepiandrosterone; Disorders of Sex Developm | 1968 |
Steroid metabolic pathways in feminizing testicular tissue.
Topics: 17-Ketosteroids; Acetone; Adolescent; Androgen-Insensitivity Syndrome; Androstanes; Biotransformatio | 1968 |
Steroid characteristics of the syndrome of testicular feminization.
Topics: Adult; Androgen-Insensitivity Syndrome; Chorionic Gonadotropin; Dehydroepiandrosterone; Disorders of | 1968 |
Virilizing male pseudohermaphroditism. Association with abnormal testicular function.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Chorion | 1969 |
De novo formation and metabolism of steroid hormones in feminizing testes: biochemical and ultrastructural studies.
Topics: 17-Ketosteroids; Acetates; Adult; Androgen-Insensitivity Syndrome; Androstanes; Carbon Isotopes; Cho | 1969 |
[Meaning of the foeto-placental unit in the steroid metabolism].
Topics: Adrenal Insufficiency; Androgens; Anencephaly; Dehydroepiandrosterone; Disorders of Sex Development; | 1969 |
[Clinical and biochemical studies in a female patient with mixed gonadal dysgenesis].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Androsterone; Body | 1969 |
Familial male pseudohermaphroditism with gynecomastia due to a testicular 17-ketosteroid reductase defect. I. Studies in vivo.
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Androstanes; Carbon Isotopes; Castration; Chro | 1971 |
Endocrine and metabolic studies in children with male pseudohermaphroditism.
Topics: Adolescent; Child; Child, Preschool; Chorionic Gonadotropin; Dehydroepiandrosterone; Disorders of Se | 1971 |
[Hard-to-classify forms of intersexuality. II. Familial male pseudohermaphroditism with lacking or supernumerary Y chromosome as mosaic].
Topics: 17-Ketosteroids; Adolescent; Androgen-Insensitivity Syndrome; Androsterone; Castration; Child; Dehyd | 1970 |
[Hard-to-classify forms of intersexuality. 3. Biosynthesis of steroids in testis of a case of male pseudohermaphroditism].
Topics: Androgen-Insensitivity Syndrome; Cholesterol; Dehydroepiandrosterone; Disorders of Sex Development; | 1970 |
Testicular tumors in the androgen insensitive pseudohermaphrodite rat: histochemistry and steroid metabolism.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Disease Models, Animal | 1970 |
[Intersex types which are difficult to classify. I. Familial masculine pseudohermaphroditism with disproportioned virilization and chromosomal aberration].
Topics: Androsterone; Chromosome Aberrations; Dehydroepiandrosterone; Disorders of Sex Development; Etiochol | 1970 |
Partial 3 -hydroxysteroid dehydrogenase (3 -HSD) deficiency in a family with congenital adrenal hyperplasia: evidence for increasing 3 -HSD activity with age.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Aging; Aldosterone; Androstanes; | 1971 |
Further in vivo studies in male pseudohermaphroditism with gynecomastia due to a testicular 17-ketosteroid reductase defect (compared to a case of testicular feminization).
Topics: 17-Ketosteroids; Adolescent; Adult; Androgen-Insensitivity Syndrome; Androsterone; Dehydroepiandrost | 1972 |
Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.
Topics: Adult; Androgen-Insensitivity Syndrome; Animals; Chorionic Gonadotropin; Chromatography, Thin Layer; | 1972 |
Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.
Topics: Adult; Androgen-Insensitivity Syndrome; Animals; Chorionic Gonadotropin; Chromatography, Thin Layer; | 1972 |
Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.
Topics: Adult; Androgen-Insensitivity Syndrome; Animals; Chorionic Gonadotropin; Chromatography, Thin Layer; | 1972 |
Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.
Topics: Adult; Androgen-Insensitivity Syndrome; Animals; Chorionic Gonadotropin; Chromatography, Thin Layer; | 1972 |
Steroid biosynthesis in vitro by gonadal tissues in true hermaphroditism.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Carbon Isotop | 1972 |
Evidence for increased cytoplasmic androgen binding in the submandibular gland of the mouse with testicular feminization.
Topics: Androgen-Insensitivity Syndrome; Androstenes; Animals; Castration; Centrifugation, Density Gradient; | 1972 |
"True agonadism": a misnomer?
Topics: 17-Ketosteroids; Androstenedione; Child, Preschool; Chorionic Gonadotropin; Corticosterone; Dehydroe | 1974 |
Feminine patterns of androgen metabolism and presence of delta5, 3beta-hydroxysteroid oxidoreductases in target organs of genetic rat male pseudohermaphrodites.
Topics: Androgens; Androstenedione; Animals; Dehydroepiandrosterone; Disorders of Sex Development; Female; H | 1974 |
Familial male pseudohermaphroditism without gynecomastia due to deficient testicular 17-ketosteroid reductase activity.
Topics: 17-Ketosteroids; Adolescent; Androstenedione; Circadian Rhythm; Dehydroepiandrosterone; Dihydrotesto | 1974 |
The response to human chorionic gonadotropin (HCG) administration in boys with and without delta5-3beta-hydroxysteroid dehydrogenase deficiency.
Topics: Adolescent; Adrenal Insufficiency; Androstenedione; Child; Child, Preschool; Chorionic Gonadotropin; | 1974 |
Children with male pseudohermaphroditism: endocrine and metabolic studies.
Topics: 17-Ketosteroids; Adolescent; Alcohol Oxidoreductases; Androgen-Insensitivity Syndrome; Androstenedio | 1971 |
Steroid excretion and biosynthesis, with special reference to 16-unsaturated C 19 steroids, in cases of testicular feminization and in a male pseudohermaphrodite.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Androgen-Insensitivity Syndrome; Androgens; Androste | 1972 |
The evaluation of testicular endocrine function before and in puberty. Effect of a single dose of human chorionic gonadotropin on urinary steroid excretion under normal and pathological conditions.
Topics: Adolescent; Adrenal Insufficiency; Adult; Child; Child, Preschool; Chorionic Gonadotropin; Chromatog | 1972 |