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dehydroepiandrosterone and Allergic Reaction

dehydroepiandrosterone has been researched along with Allergic Reaction in 8 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
" The author's own findings and the data available in the literature indicate that the androgens dehydroepiandrosterone and dehydroepiandrosterone sulfate that are secreted in the reticular area play an important role in ensuring the body's full stable adaptation to stress and simultaneously preventing stress-associated abnormalities, such as atherosclerosis, diabetes, immunodefficiency, hypertension, allergies, and cancer."4.80[Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease]. ( Obut, TA, 1998)
"In this study, we evaluated the anti-inflammatory response and the mechanism by which dehydroepiandrosterone modulates immunity in ovalbumin-sensitized asthmatic mice."3.77Dehydroepiandrosterone suppresses eosinophil infiltration and airway hyperresponsiveness via modulation of chemokines and Th2 cytokines in ovalbumin-sensitized mice. ( Huang, WC; Liou, CJ, 2011)
" Overreliance on animal models (DHEA is essentially a human molecule), different dosing protocols with non-pharmacological doses often unachievable in humans, rapid metabolism of DHEA, co-morbidities and organ-specific differences render data interpretation difficult."2.50Dehydroepiandrosterone (DHEA): hypes and hopes. ( Kuryliszyn-Moskal, A; Rutkowska-Talipska, J; Rutkowski, K; Rutkowski, R; Sowa, P, 2014)
"In Balb/c mice with pulmonary tuberculosis, there is a switch from a protective Th1-dominated cytokine profile to a non-protective profile with a Th2 component."1.30Emergent immunoregulatory properties of combined glucocorticoid and anti-glucocorticoid steroids in a model of tuberculosis. ( Arriaga, K; de la Luz Streber, M; Hernandez-Pando, R; Lightman, SL; Marti, O; Orozco, H; Pavon, L; Rook, GA, 1998)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Lokaj-Berisha, V1
Gacaferri Lumezi, B1
Berisha, N1
Rutkowski, K1
Sowa, P1
Rutkowska-Talipska, J1
Kuryliszyn-Moskal, A1
Rutkowski, R1
Kasperska-Zajac, AE1
Brzoza, ZK1
Koczy-Baron, E1
Jagodzinska, J1
Liou, CJ1
Huang, WC1
Dillon, JS1
Obut, TA1
Hernandez-Pando, R1
de la Luz Streber, M1
Orozco, H1
Arriaga, K1
Pavon, L1
Marti, O1
Lightman, SL1
Rook, GA1
Yu, CK1
Yang, BC1
Lei, HY1
Chen, YC1
Liu, YH1
Chen, CC1
Liu, CW1

Reviews

4 reviews available for dehydroepiandrosterone and Allergic Reaction

ArticleYear
Dehydroepiandrosterone (DHEA): hypes and hopes.
    Drugs, 2014, Volume: 74, Issue:11

    Topics: Adrenal Insufficiency; Aging; Animals; Bone Density; Dehydroepiandrosterone; Dietary Supplements; Hu

2014
Dehydroepiandrosterone in therapy of allergic diseases.
    Recent patents on inflammation & allergy drug discovery, 2009, Volume: 3, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Dehydroepiandrosterone; Humans; Hypersensitivity; Patents as Topic;

2009
Dehydroepiandrosterone, dehydroepiandrosterone sulfate and related steroids: their role in inflammatory, allergic and immunological disorders.
    Current drug targets. Inflammation and allergy, 2005, Volume: 4, Issue:3

    Topics: Aging; Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Cytokines; Dehydroepiandrosterone; De

2005
[Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1998, Issue:10

    Topics: Adjuvants, Immunologic; Animals; Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Su

1998

Trials

1 trial available for dehydroepiandrosterone and Allergic Reaction

ArticleYear
Low serum levels of dehydroepiandrosterone sulfate and testosterone in Albanian female patients with allergic disease.
    Scientific reports, 2021, 03-10, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Hypersensitivity

2021

Other Studies

3 other studies available for dehydroepiandrosterone and Allergic Reaction

ArticleYear
Dehydroepiandrosterone suppresses eosinophil infiltration and airway hyperresponsiveness via modulation of chemokines and Th2 cytokines in ovalbumin-sensitized mice.
    Journal of clinical immunology, 2011, Volume: 31, Issue:4

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Movement; Cells, Cultured; Chemokines; Cytokines

2011
Emergent immunoregulatory properties of combined glucocorticoid and anti-glucocorticoid steroids in a model of tuberculosis.
    QJM : monthly journal of the Association of Physicians, 1998, Volume: 91, Issue:11

    Topics: Adjuvants, Immunologic; Androstenediols; Animals; Corticosterone; Dehydroepiandrosterone; Drug Combi

1998
Attenuation of house dust mite Dermatophagoides farinae-induced airway allergic responses in mice by dehydroepiandrosterone is correlated with down-regulation of TH2 response.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29, Issue:3

    Topics: Animals; Antigens, Dermatophagoides; Cytokines; Dehydroepiandrosterone; Down-Regulation; Female; Gly

1999