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dehydroepiandrosterone and Aldosteronism

dehydroepiandrosterone has been researched along with Aldosteronism in 11 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"The practicability and tolerability of trilostane, a competitive inhibitor of 3 beta-hydroxysteroid-delta 5-dehydrogenase, for the therapy of primary aldosteronism was assessed in 1 patient with aldosterone-producing adenoma (APA) and 3 subjects with idiopathic adrenal hyperplasia (IHA)."7.67Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor). ( Ishikawa, S; Katayama, T; Kazama, T; Koike, H; Nakada, T; Yoshikawa, M, 1985)
"Six patients with primary aldosteronism (PA), one with idiopathic hyperaldosteronism (IHA), one with glucocorticoid responsible hyperaldosteronism (GRHA) and eight with essential hypertension (EH) were treated with trilostane (MWD-1822) (4 alpha, 5-epoxy-17 beta-hydroxy-3-oxo-5 alpha-androstane-2 alpha-carbonitrile), an inhibitor of adrenal steroid biosynthesis, for 9-47 days with a daily dose of 30-960 mg."7.66[The effect of trilostane, a new inhibitor of adrenal steroid biosynthesis, on blood pressure, plasma aldosterone and other steroid hormones, serum potassium and plasma renin activity in primary aldosteronism (author's transl)]. ( Fukuchi, S; Haruyama, K; Shigetomi, S; Yamazaki, M, 1982)
"We examined if measurement of adrenal androgens adds to subtype diagnostics of primary aldosteronism (PA) under cosyntropin-stimulated adrenal venous sampling (AVS)."4.12Adrenal androgens versus cortisol for primary aldosteronism subtype determination in adrenal venous sampling. ( Hinkka, T; Kokko, E; Leijon, H; Matikainen, N; Nevalainen, PI; Pörsti, I; Schalin-Jäntti, C; Soinio, M; Vesterinen, T; Viukari, M, 2022)
"The practicability and tolerability of trilostane, a competitive inhibitor of 3 beta-hydroxysteroid-delta 5-dehydrogenase, for the therapy of primary aldosteronism was assessed in 1 patient with aldosterone-producing adenoma (APA) and 3 subjects with idiopathic adrenal hyperplasia (IHA)."3.67Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor). ( Ishikawa, S; Katayama, T; Kazama, T; Koike, H; Nakada, T; Yoshikawa, M, 1985)
"Six patients with primary aldosteronism (PA), one with idiopathic hyperaldosteronism (IHA), one with glucocorticoid responsible hyperaldosteronism (GRHA) and eight with essential hypertension (EH) were treated with trilostane (MWD-1822) (4 alpha, 5-epoxy-17 beta-hydroxy-3-oxo-5 alpha-androstane-2 alpha-carbonitrile), an inhibitor of adrenal steroid biosynthesis, for 9-47 days with a daily dose of 30-960 mg."3.66[The effect of trilostane, a new inhibitor of adrenal steroid biosynthesis, on blood pressure, plasma aldosterone and other steroid hormones, serum potassium and plasma renin activity in primary aldosteronism (author's transl)]. ( Fukuchi, S; Haruyama, K; Shigetomi, S; Yamazaki, M, 1982)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Viukari, M1
Kokko, E1
Pörsti, I1
Leijon, H1
Vesterinen, T1
Hinkka, T1
Soinio, M1
Schalin-Jäntti, C1
Matikainen, N1
Nevalainen, PI1
KOMOR, K1
Shigetomi, S1
Fukuchi, S1
Haruyama, K1
Yamazaki, M1
New, MI1
Levine, LS1
Terayama, Y1
Furusawa, M1
Morita, S1
Kido, K1
Tanaka, T1
Eba, H1
Nigawara, K1
Hitomi, H1
Sugawara, S1
Yagihashi, Y1
Kogawa, T1
Kawamata, A1
Tulachan, Y1
Funyu, T1
Hanson, JA1
Weber, A1
Reznek, RH1
Cotterill, AM1
Ross, RJ1
Harris, RJ1
Armstrong, P1
Savage, MO1
Kołomecki, K1
Stepień, H1
Narebski, JM1
Nakada, T1
Kazama, T1
Koike, H1
Yoshikawa, M1
Ishikawa, S1
Katayama, T1
Aiba, M1
Iri, H1
Suzuki, H1
Kageyama, K1
Kawai, T1
Abe, O1
Murai, M1
Tazaki, H1
Saruta, T1
Melby, JC1
Metcalf, MG1

Reviews

2 reviews available for dehydroepiandrosterone and Aldosteronism

ArticleYear
Hypertension of childhood with suppressed renin.
    Endocrine reviews, 1980,Fall, Volume: 1, Issue:4

    Topics: 18-Hydroxydesoxycorticosterone; 20-alpha-Dihydroprogesterone; Adolescent; Adrenal Cortex; Adrenal Hy

1980
Assessment of adrenocortical function.
    The New England journal of medicine, 1971, Sep-23, Volume: 285, Issue:13

    Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aldoster

1971

Other Studies

9 other studies available for dehydroepiandrosterone and Aldosteronism

ArticleYear
Adrenal androgens versus cortisol for primary aldosteronism subtype determination in adrenal venous sampling.
    Clinical endocrinology, 2022, Volume: 97, Issue:3

    Topics: Adrenal Glands; Aldosterone; Androgens; Androstenedione; Cosyntropin; Dehydroepiandrosterone; Humans

2022
[ON THE TREATMENT OF ADRENAL CORTEX DISEASES].
    Magyar belorvosi archivum (1955), 1963, Volume: 16

    Topics: Addison Disease; Adrenal Cortex Diseases; Adrenal Insufficiency; Adrenocortical Hyperfunction; Adren

1963
[The effect of trilostane, a new inhibitor of adrenal steroid biosynthesis, on blood pressure, plasma aldosterone and other steroid hormones, serum potassium and plasma renin activity in primary aldosteronism (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1982, Mar-20, Volume: 58, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Hyp

1982
[Corticoids secretion in primary aldosteronism. I. Diurnal variation and the effect of dexamethasone (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1980, Jan-20, Volume: 56, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Adult; Aldosterone; Circadian Rhythm; Corticosterone; Cortis

1980
Magnetic resonance imaging of adrenocortical adenomas in childhood: correlation with computed tomography and ultrasound.
    Pediatric radiology, 1996, Volume: 26, Issue:11

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hor

1996
Vascular endothelial growth factor and basic fibroblast growth factor evaluation in blood serum of patients with hormonally active and inactive adrenal gland tumours.
    Cytobios, 2000, Volume: 101, Issue:396

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Medulla; Adrenalectomy; Adult; Aged; Carc

2000
Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor).
    Urology, 1985, Volume: 25, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adreno

1985
Numerous mast cells in an 11-deoxycorticosterone-producing adrenocortical tumor. Histologic evaluation of benignancy and comparison with mast cell distribution in adrenal glands and neoplastic counterparts of 67 surgical specimens.
    Archives of pathology & laboratory medicine, 1985, Volume: 109, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Carcinoma, Renal Cell; Dehydroepiandro

1985
Rapid gas chromatographic assay for dehydroepiandrosterone in urine.
    Clinical biochemistry, 1971, Volume: 4, Issue:4

    Topics: Adolescent; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropi

1971