Page last updated: 2024-11-07

dehydroepiandrosterone and Alcohol Drinking

dehydroepiandrosterone has been researched along with Alcohol Drinking in 21 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
"The present study compared two putative pharmacotherapies for alcohol abuse and dependence, dehydroepiandrosterone (DHEA) and pregnanolone, with two Food and Drug Administration (FDA)-approved pharmacotherapies, naltrexone and acamprosate."7.81Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats. ( Amato, RJ; Hulin, MW; Lawrence, MN; Weed, PF; Winsauer, PJ, 2015)
"To measure the association between alcohol intake and 11 hormones and peptides in postmenopausal breast cancer survivors and to evaluate whether this association differs by tamoxifen use."7.74Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors. ( Ballard-Barbash, R; Baumgartner, KB; Baumgartner, RN; Bernstein, L; Gilliland, F; Koprowski, C; McTiernan, A; Neuhouser, ML; Ulrich, CM; Wayne, S; Wiggins, C, 2008)
"The present study compared two putative pharmacotherapies for alcohol abuse and dependence, dehydroepiandrosterone (DHEA) and pregnanolone, with two Food and Drug Administration (FDA)-approved pharmacotherapies, naltrexone and acamprosate."3.81Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats. ( Amato, RJ; Hulin, MW; Lawrence, MN; Weed, PF; Winsauer, PJ, 2015)
"To measure the association between alcohol intake and 11 hormones and peptides in postmenopausal breast cancer survivors and to evaluate whether this association differs by tamoxifen use."3.74Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors. ( Ballard-Barbash, R; Baumgartner, KB; Baumgartner, RN; Bernstein, L; Gilliland, F; Koprowski, C; McTiernan, A; Neuhouser, ML; Ulrich, CM; Wayne, S; Wiggins, C, 2008)
"Androstenedione levels were significantly lowered and the testosterone:androstenedione ratio significantly elevated by alcohol among both OC- and OC+ subjects."2.69Acute effect of alcohol on androgens in premenopausal women. ( Fukunaga, T; Mäkisalo, H; Peter Eriksson, CJ; Sarkola, T, 2000)
" In contrast, multiple doses of DHEA consistently decreased intake of an 18% ethanol concentration in both groups after repeated injections and 3 doses of DHEA (10, 32, and 56 mg/kg) administered with various ethanol concentrations dose-dependently shifted the ethanol-concentration curves for the volume and dosage of ethanol consumed downward."1.35Effects of pregnanolone and dehydroepiandrosterone on ethanol intake in rats administered ethanol or saline during adolescence. ( Gurkovskaya, OV; Leonard, ST; Lewis, PB; Winsauer, PJ, 2009)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (14.29)18.2507
2000's8 (38.10)29.6817
2010's9 (42.86)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Ganson, KT1
Mitchison, D1
Murray, SB1
Nagata, JM1
Erwin, LL1
Nilges, MR1
DeLarge, AF1
Weed, PF2
Winsauer, PJ6
Hulin, MW3
Lawrence, MN1
Amato, RJ3
Schrieks, IC1
Joosten, MM1
Klöpping-Ketelaars, WA1
Witkamp, RF1
Hendriks, HF1
Wayne, S1
Neuhouser, ML1
Ulrich, CM1
Koprowski, C1
Wiggins, C1
Baumgartner, KB1
Bernstein, L1
Baumgartner, RN1
Gilliland, F1
McTiernan, A1
Ballard-Barbash, R1
Weiss, EP1
Shah, K1
Fontana, L1
Lambert, CP1
Holloszy, JO1
Villareal, DT1
Gurkovskaya, OV2
Leonard, ST2
Lewis, PB2
Worrel, ME1
Goh, VH1
Tong, TY1
Pichini, S1
De Luca, R1
Pellegrini, M1
Marchei, E1
Rotolo, MC1
Spoletini, R1
D'Aloja, P1
Pacifici, R1
Mortali, C1
Scaravelli, G1
Wemm, S1
Fanean, A1
Baker, A1
Blough, ER1
Mewaldt, S1
Bardi, M1
Onland-Moret, NC1
Peeters, PH1
van der Schouw, YT1
Grobbee, DE1
van Gils, CH1
Rolland, YM1
Perry, HM1
Patrick, P1
Banks, WA1
Morley, JE1
Dorgan, JF2
Reichman, ME1
Judd, JT1
Brown, C1
Longcope, C1
Schatzkin, A1
Campbell, WS1
Franz, C1
Kahle, L1
Taylor, PR2
Haffner, SM1
Valdez, RA1
Stern, MP1
Katz, MS1
Hautanen, A1
Adlercreutz, H1
Sarkola, T1
Fukunaga, T1
Mäkisalo, H1
Peter Eriksson, CJ1
Bradlow, HL1
Hartman, TJ1
Woodson, K1
Virtamo, J1
Tangrea, JA1
Heinonen, OP1
Barrett, MJ1
Albanes, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is DHEA Replacement Beneficial?[NCT00182975]Phase 3142 participants (Actual)Interventional2002-09-30Completed
Diabetes and Cardiovascular Risk In Mexico City (San Antonio Heart Study)[NCT00005146]0 participants Observational1979-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for dehydroepiandrosterone and Alcohol Drinking

ArticleYear
Moderate alcohol consumption after a mental stressor attenuates the endocrine stress response.
    Alcohol (Fayetteville, N.Y.), 2016, Volume: 57

    Topics: Adrenocorticotropic Hormone; Adult; Alcohol Drinking; Beer; Cross-Over Studies; Dehydroepiandrostero

2016
Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone.
    The American journal of clinical nutrition, 2009, Volume: 89, Issue:5

    Topics: Absorptiometry, Photon; Aged; Alcohol Drinking; Body Mass Index; Bone Density; Calcium; Dehydroepian

2009
Acute effect of alcohol on androgens in premenopausal women.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2000, Volume: 35, Issue:1

    Topics: Adult; Alcohol Drinking; Androstenedione; Central Nervous System Depressants; Contraceptives, Oral,

2000
Effects of long-term alpha-tocopherol supplementation on serum hormones in older men.
    The Prostate, 2001, Jan-01, Volume: 46, Issue:1

    Topics: Alcohol Drinking; Androstenedione; Cholesterol; Dehydroepiandrosterone; Eating; Follow-Up Studies; H

2001

Other Studies

17 other studies available for dehydroepiandrosterone and Alcohol Drinking

ArticleYear
Legal Performance-Enhancing Substances and Substance Use Problems Among Young Adults.
    Pediatrics, 2020, Volume: 146, Issue:3

    Topics: Adolescent; Adult; Alcohol Drinking; Alcoholic Intoxication; Amino Acids; Athletes; Body Mass Index;

2020
Effects of noncontingent ethanol, DHEA, and pregnanolone administration on ethanol self-administration in outbred female rats.
    Alcohol (Fayetteville, N.Y.), 2019, Volume: 75

    Topics: Alcohol Drinking; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Ethanol; Female

2019
Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats.
    Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:2

    Topics: Acamprosate; Alcohol Drinking; Alcoholism; Animals; Dehydroepiandrosterone; Dose-Response Relationsh

2015
Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:11

    Topics: Alcohol Drinking; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cross-Sectional Studies; Dehydr

2008
Effects of pregnanolone and dehydroepiandrosterone on ethanol intake in rats administered ethanol or saline during adolescence.
    Alcoholism, clinical and experimental research, 2009, Volume: 33, Issue:7

    Topics: Age Factors; Alcohol Drinking; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Et

2009
Effects of 7-keto dehydroepiandrosterone on voluntary ethanol intake in male rats.
    Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:4

    Topics: Alcohol Drinking; Animals; Dehydroepiandrosterone; Ethanol; Male; Rats; Rats, Long-Evans; Receptors,

2011
The moderating impact of lifestyle factors on sex steroids, sexual activities and aging in Asian men.
    Asian journal of andrology, 2011, Volume: 13, Issue:4

    Topics: Adipose Tissue; Adult; Aged; Aging; Alcohol Drinking; Asian People; Dehydroepiandrosterone; Dehydroe

2011
GABA(A) receptor modulation during adolescence alters adult ethanol intake and preference in rats.
    Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:2

    Topics: Aging; Alcohol Drinking; Animals; Data Interpretation, Statistical; Dehydroepiandrosterone; Dose-Res

2012
Hair and urine testing to assess drugs of abuse consumption in couples undergoing assisted reproductive technology (ART).
    Forensic science international, 2012, May-10, Volume: 218, Issue:1-3

    Topics: Adult; Alcohol Drinking; Cannabinoids; Cocaine; Dehydroepiandrosterone; Female; Hair; Humans; Infert

2012
A comparison of dehydroepiandrosterone and 7-keto dehydroepiandrosterone with other drugs that modulate ethanol intake in rats responding under a multiple schedule.
    Behavioural pharmacology, 2012, Volume: 23, Issue:3

    Topics: Alcohol Drinking; Animals; Dehydroepiandrosterone; Ethanol; Male; Rats; Rats, Long-Evans; Reinforcem

2012
Problematic drinking and physiological responses among female college students.
    Alcohol (Fayetteville, N.Y.), 2013, Volume: 47, Issue:2

    Topics: Adaptation, Psychological; Adolescent; Adrenal Glands; Alcohol Drinking; Alcoholism; Behavior; Dehyd

2013
Alcohol and endogenous sex steroid levels in postmenopausal women: a cross-sectional study.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:3

    Topics: Aged; Alcohol Drinking; Androstenedione; Breast Neoplasms; Cross-Sectional Studies; Dehydroepiandros

2005
Loss of appendicular muscle mass and loss of muscle strength in young postmenopausal women.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2007, Volume: 62, Issue:3

    Topics: Alcohol Drinking; Anthropometry; Body Composition; Body Mass Index; Bone Density; Cholesterol, HDL;

2007
The relation of reported alcohol ingestion to plasma levels of estrogens and androgens in premenopausal women (Maryland, United States).
    Cancer causes & control : CCC, 1994, Volume: 5, Issue:1

    Topics: Adult; Alcohol Drinking; Androgens; Androstenedione; Body Mass Index; Body Weight; Breast Neoplasms;

1994
Obesity, body fat distribution and sex hormones in men.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1993, Volume: 17, Issue:11

    Topics: Adipose Tissue; Adult; Alcohol Drinking; Anthropometry; Body Constitution; Cohort Studies; Dehydroep

1993
Hyperinsulinaemia, dyslipidaemia and exaggerated adrenal androgen response to adrenocorticotropin in male smokers.
    Diabetologia, 1993, Volume: 36, Issue:12

    Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Alcohol Drinking; Androstenedione;

1993
Feeding DHEA to C57/B167 mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 2000, Volume: 224, Issue:4

    Topics: Alcohol Drinking; Animals; Body Weight; Dehydroepiandrosterone; Eating; Food Preferences; Male; Mice

2000