Page last updated: 2024-11-07

dehydroepiandrosterone and Alcohol Abuse

dehydroepiandrosterone has been researched along with Alcohol Abuse in 16 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"The present study compared two putative pharmacotherapies for alcohol abuse and dependence, dehydroepiandrosterone (DHEA) and pregnanolone, with two Food and Drug Administration (FDA)-approved pharmacotherapies, naltrexone and acamprosate."7.81Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats. ( Amato, RJ; Hulin, MW; Lawrence, MN; Weed, PF; Winsauer, PJ, 2015)
"We compared serum concentrations of total and free testosterone, androstenedione, dehydroepiandrosterone sulfate (DHEAS), and sex-hormone-binding globulin in 40 pregnant women exhibiting consistent alcohol abuse and in 20 abstinent pregnant controls."7.67Testosterone, androstenedione, dehydroepiandrosterone sulfate, and sex-hormone-binding globulin in pregnant alcohol abusers. ( Halmesmäki, E; Stenman, UH; Ylikorkala, O, 1988)
"The present study compared two putative pharmacotherapies for alcohol abuse and dependence, dehydroepiandrosterone (DHEA) and pregnanolone, with two Food and Drug Administration (FDA)-approved pharmacotherapies, naltrexone and acamprosate."3.81Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats. ( Amato, RJ; Hulin, MW; Lawrence, MN; Weed, PF; Winsauer, PJ, 2015)
"We compared serum concentrations of total and free testosterone, androstenedione, dehydroepiandrosterone sulfate (DHEAS), and sex-hormone-binding globulin in 40 pregnant women exhibiting consistent alcohol abuse and in 20 abstinent pregnant controls."3.67Testosterone, androstenedione, dehydroepiandrosterone sulfate, and sex-hormone-binding globulin in pregnant alcohol abusers. ( Halmesmäki, E; Stenman, UH; Ylikorkala, O, 1988)
"To assess the effects of drug and alcohol abuse (DAA) on the physical changes and hormones of puberty in adolescents, 26 males (13 5/12-22 years) enrolled in a drug rehabilitation program were examined."1.27Effects of drug and alcohol abuse upon pituitary-testicular function in adolescent males. ( Barnes, J; Diamond, F; Duckett, G; Hu, CS; MacDonald, D; Ringenberg, L; Root, A; Sweetland, M, 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's2 (12.50)18.2507
2000's3 (18.75)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Weinland, C1
Mühle, C1
von Zimmermann, C1
Kornhuber, J1
Lenz, B1
Hulin, MW1
Lawrence, MN1
Amato, RJ1
Weed, PF1
Winsauer, PJ2
Kärkkäinen, O1
Häkkinen, MR1
Auriola, S1
Kautiainen, H1
Tiihonen, J1
Storvik, M1
Garcia-Marchena, N1
Pavon, FJ1
Pastor, A1
Araos, P1
Pedraz, M1
Romero-Sanchiz, P1
Calado, M1
Suarez, J1
Castilla-Ortega, E1
Orio, L1
Boronat, A1
Torrens, M1
Rubio, G1
de la Torre, R1
Rodriguez de Fonseca, F1
Serrano, A1
Gurkovskaya, OV1
Wemm, S1
Fanean, A1
Baker, A1
Blough, ER1
Mewaldt, S1
Bardi, M1
Hill, M1
Popov, P1
Havlíková, H1
Kancheva, L1
Vrbíková, J1
Kancheva, R1
Pouzar, V1
Cerný, I1
Stárka, L1
Purdy, RH1
Valenzuela, CF1
Janak, PH1
Finn, DA1
Biggio, G1
Bäckström, T1
Halberg, F1
Chiodera, P1
Pignatti, D1
Maestri, E1
Zanardi, G1
Degliantoni, G1
Orlando, S1
Volpi, R1
Delsignore, R1
Bergman, B1
Brismar, B1
Adinoff, B1
Kiser, JM1
Martin, PR1
Linnoila, M1
Diamond, F1
Ringenberg, L1
MacDonald, D1
Barnes, J1
Hu, CS1
Duckett, G1
Sweetland, M1
Root, A1
Ylikorkala, O1
Stenman, UH1
Halmesmäki, E1
Gordon, ES1
Fabre, LF1
Pasco, PJ1
Liegel, JM1
Farmer, RW1

Reviews

2 reviews available for dehydroepiandrosterone and Alcohol Abuse

ArticleYear
Quo vadis basic and clinical chronobiology: promise for health maintenance.
    The American journal of anatomy, 1983, Volume: 168, Issue:4

    Topics: Adrenal Cortex; Alcoholism; Aldosterone; Biological Clocks; Blood Pressure; Breast Neoplasms; Cardio

1983
Metabolic aspects of obesity.
    Advances in metabolic disorders, 1970, Volume: 4

    Topics: Acidosis; Adenosine Triphosphate; Adipose Tissue; Adrenal Cortex Hormones; Alcoholism; Animals; Body

1970

Trials

1 trial available for dehydroepiandrosterone and Alcohol Abuse

ArticleYear
Response of dehydroepiandrosterone to corticotropin-releasing hormone stimulation in alcohol-dependent subjects.
    Biological psychiatry, 1996, Dec-15, Volume: 40, Issue:12

    Topics: Adult; Alcoholism; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Humans; Temperance

1996

Other Studies

13 other studies available for dehydroepiandrosterone and Alcohol Abuse

ArticleYear
Sulphated dehydroepiandrosterone serum levels are reduced in women with alcohol use disorder and correlate negatively with craving: A sex-separated cross-sectional and longitudinal study.
    Addiction biology, 2022, Volume: 27, Issue:2

    Topics: Alcoholism; Craving; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Humans; Longitudinal S

2022
Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats.
    Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:2

    Topics: Acamprosate; Alcohol Drinking; Alcoholism; Animals; Dehydroepiandrosterone; Dose-Response Relationsh

2015
Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics.
    Alcohol (Fayetteville, N.Y.), 2016, Volume: 52

    Topics: Adolescent; Adult; Aged; Alcoholism; Brain; Dehydroepiandrosterone; Female; Humans; Male; Middle Age

2016
Plasma concentrations of oleoylethanolamide and other acylethanolamides are altered in alcohol-dependent patients: effect of length of abstinence.
    Addiction biology, 2017, Volume: 22, Issue:5

    Topics: Adult; Alcohol Abstinence; Alcoholism; Amides; Arachidonic Acids; Case-Control Studies; Dehydroepian

2017
Discriminative stimulus effects of ethanol, pregnanolone, and dehydroepiandrosterone (DHEA) in rats administered ethanol or saline as adolescents.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 93, Issue:1

    Topics: Adolescent; Adult; Age Factors; Alcoholism; Animals; Dehydroepiandrosterone; Discrimination, Psychol

2009
Problematic drinking and physiological responses among female college students.
    Alcohol (Fayetteville, N.Y.), 2013, Volume: 47, Issue:2

    Topics: Adaptation, Psychological; Adolescent; Adrenal Glands; Alcohol Drinking; Alcoholism; Behavior; Dehyd

2013
Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction.
    Steroids, 2005, Volume: 70, Issue:8

    Topics: Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gas Chromatog

2005
Neuroactive steroids and ethanol.
    Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:7

    Topics: Alcoholism; Animals; Brain; Dehydroepiandrosterone; Female; Fetal Alcohol Spectrum Disorders; Humans

2005
[Blood levels of prolactin, dehydroepiandrosterone sulfate, cortisol, testosterone and 17-beta-estradiol in chronic alcoholism].
    Giornale di clinica medica, 1981, Volume: 62, Issue:7

    Topics: Adult; Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Fatty Liver; H

1981
Hormone levels and personality traits in abusive and suicidal male alcoholics.
    Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:2

    Topics: Adult; Aggression; Alcoholism; Antisocial Personality Disorder; Dehydroepiandrosterone; Dehydroepian

1994
Effects of drug and alcohol abuse upon pituitary-testicular function in adolescent males.
    Journal of adolescent health care : official publication of the Society for Adolescent Medicine, 1986, Volume: 7, Issue:1

    Topics: Adolescent; Alcoholism; Dehydroepiandrosterone; Follicle Stimulating Hormone; Follow-Up Studies; Hum

1986
Testosterone, androstenedione, dehydroepiandrosterone sulfate, and sex-hormone-binding globulin in pregnant alcohol abusers.
    Obstetrics and gynecology, 1988, Volume: 71, Issue:5

    Topics: Adult; Alcoholism; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female;

1988
Abnormal testosterone excretion in men alcoholics.
    Quarterly journal of studies on alcohol, 1973, Volume: 34, Issue:1

    Topics: 17-Ketosteroids; Adult; Alcoholism; Androsterone; Dehydroepiandrosterone; Ethanol; Etiocholanolone;

1973