Page last updated: 2024-11-07

dehydroepiandrosterone and Airflow Obstruction, Chronic

dehydroepiandrosterone has been researched along with Airflow Obstruction, Chronic in 3 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"It was previously shown that dehydroepiandrosterone (DHEA) reverses chronic hypoxia-induced pulmonary hypertension (PH) in rats, but whether DHEA can improve the clinical and hemodynamic status of patients with PH associated to chronic obstructive pulmonary disease (PH-COPD) has not been studied whereas it is a very severe poorly treated disease."9.16Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): a pilot study. ( Baulieu, EÉ; Billes, MA; Doutreleau, S; Dromer, C; Dumas de La Roque, E; Fayon, M; Jougon, J; Kraemer, JP; Marthan, R; Metivier, AC; Moore, N; Savineau, JP, 2012)
"It was previously shown that dehydroepiandrosterone (DHEA) reverses chronic hypoxia-induced pulmonary hypertension (PH) in rats, but whether DHEA can improve the clinical and hemodynamic status of patients with PH associated to chronic obstructive pulmonary disease (PH-COPD) has not been studied whereas it is a very severe poorly treated disease."5.16Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): a pilot study. ( Baulieu, EÉ; Billes, MA; Doutreleau, S; Dromer, C; Dumas de La Roque, E; Fayon, M; Jougon, J; Kraemer, JP; Marthan, R; Metivier, AC; Moore, N; Savineau, JP, 2012)
"In patients with chronic obstructive pulmonary disease (COPD) weight loss frequently occurs that may ultimately lead to cachexia as a serious co-morbidity, indicating severely impaired functional capacity, health status and increased mortality."1.34Anorexia in chronic obstructive pulmonary disease--association to cachexia and hormonal derangement. ( Anker, SD; Doehner, W; Hoernig, S; John, M; Koehler, F; Witt, C, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karametos, I1
Tsiboli, P1
Togousidis, I1
Hatzoglou, C1
Giamouzis, G1
Gourgoulianis, KI1
Dumas de La Roque, E1
Savineau, JP1
Metivier, AC1
Billes, MA1
Kraemer, JP1
Doutreleau, S1
Jougon, J1
Marthan, R1
Moore, N1
Fayon, M1
Baulieu, EÉ1
Dromer, C1
Koehler, F1
Doehner, W1
Hoernig, S1
Witt, C1
Anker, SD1
John, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind, Randomised, Placebo-controlled Phase III Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults[NCT00581087]Phase 360 participants (Anticipated)Interventional2007-01-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for dehydroepiandrosterone and Airflow Obstruction, Chronic

ArticleYear
Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): a pilot study.
    Annales d'endocrinologie, 2012, Volume: 73, Issue:1

    Topics: Adult; Dehydroepiandrosterone; Exercise Test; Female; Hemodynamics; Humans; Hypertension, Pulmonary;

2012

Other Studies

2 other studies available for dehydroepiandrosterone and Airflow Obstruction, Chronic

ArticleYear
Chronic Obstructive Pulmonary Disease as a Main Factor of Premature Aging.
    International journal of environmental research and public health, 2019, 02-13, Volume: 16, Issue:4

    Topics: Aged; Aged, 80 and over; Aging, Premature; Biomarkers; Dehydroepiandrosterone; Female; Growth Hormon

2019
Anorexia in chronic obstructive pulmonary disease--association to cachexia and hormonal derangement.
    International journal of cardiology, 2007, Jun-25, Volume: 119, Issue:1

    Topics: Anorexia; Appetite; Biomarkers; Body Mass Index; Cachexia; Dehydroepiandrosterone; Energy Metabolism

2007