dehydroepiandrosterone has been researched along with Aging in 543 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) age-related withdrawal is very likely to be involved in the aging process and the onset of age-related diseases, giving rise to the question of whether preventing or compensating the decline of these steroids may have endocrine and clinical benefits." | 9.11 | Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency. ( Bernardi, F; Genazzani, AD; Genazzani, AR; Inglese, S; Lombardi, I; Luisi, M; Pieri, M; Rovati, L, 2004) |
| "The secretion and the blood levels of the adrenal steroid dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) decrease profoundly with age, and the question is posed whether administration of the steroid to compensate for the decline counteracts defects associated with aging." | 9.09 | Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. ( Baulieu, EE; de Lacharrière, O; Debuire, B; Faucounau, V; Forette, F; Girard, L; Girerd, X; Hervy, MP; Lahlou, N; Latour, F; Le Bouc, Y; Leaud, MC; Legrain, S; Mokrane, A; Nouveau, S; Pitti-Ferrandi, H; Raison, J; Rakoto-Arison, B; Raynaud, A; Roger, M; Souberbielle, JC; Thomas, G; Trivalle, C, 2000) |
| "The endocrine system of aging males reveals changes of more or less unknown significance for estrogens, dehydroepiandrosterone (DHEA), melatonin and growth hormone." | 8.82 | [Hormone therapy in the aging male. Estrogen, DHEA, melatonin, somatotropin]. ( Kliesch, S, 2004) |
| "Dehydroepiandrosterone (DHEA) has attracted considerable attention as a means against the decrements of aging." | 8.82 | Dehydroepiandrosterone treatment in the aging male--what should the urologist know? ( Fauteck, JD; Hoesl, CE; Oettel, M; Römmler, A; Saad, F, 2005) |
| "Almost every female classic galactosemia patient develops primary ovarian insufficiency (POI)." | 7.91 | Dehydroepiandrosterone supplementation attenuates ovarian ageing in a galactose-induced primary ovarian insufficiency rat model. ( Akouri, R; Demir, N; Erman, M; Gunduz, T; Ozekinci, M; Sozen, B, 2019) |
| "The aim of this study was to investigate the effects of aging on the central nervous system steroid and myelin basic protein (MBP) profiles." | 7.78 | The effects of aging on the central nervous system steroid profiles and myelin basic protein in rats. ( Cenesiz, S; Ciftci, G; Gultiken, ME; Karayigit, MO; Nisbet, C; Yarim, GF; Yarim, M, 2012) |
| "Dehydroepiandrosterone (DHEA), one of the major steroid hormones, and its ester have recently received attention with regard to aging and age-related diseases like Alzheimer and others." | 7.74 | Effect of dehydroepiandrosterone (DHEA) on monoamine oxidase activity, lipid peroxidation and lipofuscin accumulation in aging rat brain regions. ( Baquer, NZ; Kale, RK; Kumar, P; Sharma, D; Taha, A, 2008) |
| "Considering the results of the Massachusetts Male Aging Study (1994) we undertook the current investigation in an attempt to clarify the role of dehydroepiandrosterone sulphate (DHEAS), testosterone and lipids on age related deterioration of erectile function." | 7.73 | Are dehydroepiandrosterone sulphate and lipids associated with erectile dysfunction? ( Kumanov, P; Tomova, A, 2005) |
| "A decline in dehydroepiandrosterone (DHEA) and GH levels with aging may be associated with frailty and morbidity." | 7.73 | Dehydroepiandrosterone restoration of growth hormone gene expression in aging female rats, in vivo and in vitro: evidence for actions via estrogen receptors. ( Childs, GV; Iruthayanathan, M; Zhou, YH, 2005) |
| "240 C57BL/6 mice were treated, from the age of 21 months until death, by normobaric hypoxia (11% FIO2) or normoxia, both with and without dehydroepiandrosterone sulfate (25 mg/kg in drinking water) (4 groups, N = 60)." | 7.73 | Hypoxia and dehydroepiandrosterone in old age: a mouse survival study. ( Baulieu, EE; Debonneuil, EH; Quillard, J, 2006) |
| "To evaluate whether dehydroepiandrosterone (DHEA) ameliorates the decreased insulin sensitivity in older rats, hyperinsulinemic euglycemic clamp studies were performed in rats of various age groups previously treated with DHEA." | 7.70 | Dehydroepiandrosterone (DHEA) ameliorates the insulin sensitivity in older rats. ( Aoki, K; Kanesiro, M; Mukasa, K; Okamura, J; Saito, T; Satoh, S; Sekihara, H, 1998) |
| "Dehydroepiandrosterone (DHEA) has been shown to exert a beneficial influence on some aging-associated deficits in rodents." | 7.69 | Dehydroepiandrosterone administration reverses the inhibitory influence of aging on gonadotrophin-releasing hormone gene expression in the male and female rat brain. ( Givalois, L; Li, S; Pelletier, G, 1997) |
| ", food restriction and chronic dehydroepiandrosterone (DHEA) treatment), or a production of obesity by the presence of the ob (obese) gene or by gold thioglucose-induced hyperphagia alter the rate of binding of 3H-7,12-dimethylbenz(a)anthracene (3H-DMBA) to mouse skin deoxyribonucleic acid (DNA)." | 7.66 | Effect of food restriction, dehydroepiandrosterone, or obesity on the binding of 3H-7,12-dimethylbenz(a)anthracene to mouse skin DNA. ( Pashko, LL; Schwartz, AG, 1983) |
| "Dehydroepiandrosterone replacement in hypoadrenalism modestly improved insulin sensitivity and altered the lipid profile, but it remains uncertain whether these changes improve any patient-important outcomes." | 6.44 | Dehydroepiandrosterone in adrenal insufficiency and ageing. ( Bhagra, S; Nair, KS; Nippoldt, TB, 2008) |
| "Corticosterone was measured by radioimmunoassay and DHEA by ELISA." | 5.91 | Developmental Programming-Aging Interactions Have Sex-Specific and Developmental Stage of Exposure Outcomes on Life Course Circulating Corticosterone and Dehydroepiandrosterone (DHEA) Concentrations in Rats Exposed to Maternal Protein-Restricted Diets. ( Chavira, R; Gerow, KG; Lomas-Soria, C; Nathanielsz, PW; Reyes-Castro, LA; Rodríguez-González, GL; Zambrano, E, 2023) |
| "Dehydroepiandrosterone (DHEA) is an adrenal steroid that previously has been shown to produce antiobesity, antidiabetic, cancer preventive, and antiautoimmune effects in laboratory rodents." | 5.27 | Inhibition of proteinuria development in aging Sprague-Dawley rats and C57BL/6 mice by long-term treatment with dehydroepiandrosterone. ( Fairman, DK; Pashko, LL; Schwartz, AG, 1986) |
| "Skeletal muscle can synthesize testosterone and 5α-dihydrotestosterone (DHT) from dehydroepiandrosterone (DHEA) via steroidogenic enzymes in vitro, but hormone levels and steroidogenic enzyme expression decline with aging." | 5.19 | Resistance training restores muscle sex steroid hormone steroidogenesis in older men. ( Fujita, S; Hamaoka, T; Iemitsu, M; Kurihara, T; Matsutani, K; Sato, K, 2014) |
| "Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) decrease with aging and are important androgen and estrogen precursors in older adults." | 5.12 | Effects of dehydroepiandrosterone replacement therapy on bone mineral density in older adults: a randomized, controlled trial. ( Dahl, DJ; Gozansky, WS; Jankowski, CM; Kittelson, JM; Kohrt, WM; Schwartz, RS; Scott, SM; Van Pelt, RE, 2006) |
| "Levels of dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS), the major secretory products of the adrenal gland, decline dramatically with age, concurrent with the onset of degenerative changes and chronic diseases associated with aging." | 5.12 | The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methods. ( Barrett-Connor, E; Kritz-Silverstein, D; Laughlin, GA; von Mühlen, D, 2007) |
| "Aging is associated with diminished gonadal steroid and GH/IGF-I axis activity; whether these changes contribute to the parallel declines of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) production is unknown, as are the effects of sex steroid and/or GH administration on DHEA and DHEAS production." | 5.12 | Dehydroepiandrosterone secretion in healthy older men and women: effects of testosterone and growth hormone administration in older men. ( Baldwin, HL; Bhasin, S; Blackman, MR; Harman, SM; Johnson, ML; Muniyappa, R; Sorkin, JD; Wong, KA, 2006) |
| "Dehydroepiandrosterone (DHEA) and testosterone are widely promoted as antiaging supplements, but the long-term benefits, as compared with potential harm, are unknown." | 5.12 | DHEA in elderly women and DHEA or testosterone in elderly men. ( Basu, A; Basu, R; Cobelli, C; Dalla Man, C; Dhatariya, K; Jensen, MD; Khosla, S; Klee, GG; Melton, LJ; Nair, KS; Nehra, A; O'Brien, P; Rizza, RA; Short, KR; Smith, GE; Tindall, DJ; Toffolo, G; Vittone, JL, 2006) |
| "Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) age-related withdrawal is very likely to be involved in the aging process and the onset of age-related diseases, giving rise to the question of whether preventing or compensating the decline of these steroids may have endocrine and clinical benefits." | 5.11 | Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency. ( Bernardi, F; Genazzani, AD; Genazzani, AR; Inglese, S; Lombardi, I; Luisi, M; Pieri, M; Rovati, L, 2004) |
| "The compensation of the deficit of dehydroepiandrosterone during aging using a 50-mg/d dose does not induce beneficial effects on muscle state in healthy subjects." | 5.10 | Effect of 1-year oral administration of dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: a double-blind placebo-controlled trial. ( Baulieu, EE; Denot-Ledunois, S; Fardeau, M; Fayet, G; Forette, F; Hogrel, JY; Marini, JF; Percheron, G, 2003) |
| "The secretion and the blood levels of the adrenal steroid dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) decrease profoundly with age, and the question is posed whether administration of the steroid to compensate for the decline counteracts defects associated with aging." | 5.09 | Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. ( Baulieu, EE; de Lacharrière, O; Debuire, B; Faucounau, V; Forette, F; Girard, L; Girerd, X; Hervy, MP; Lahlou, N; Latour, F; Le Bouc, Y; Leaud, MC; Legrain, S; Mokrane, A; Nouveau, S; Pitti-Ferrandi, H; Raison, J; Rakoto-Arison, B; Raynaud, A; Roger, M; Souberbielle, JC; Thomas, G; Trivalle, C, 2000) |
| "Aging in humans is accompanied by a progressive decline in the secretion of the adrenal androgens dehydroepiandrosterone (DHEA) and DHEA sulfate (DS), paralleling that of the GH-insulin-like growth factor-I (GH-IGF-I) axis." | 5.07 | Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. ( Morales, AJ; Nelson, JC; Nolan, JJ; Yen, SS, 1994) |
| "Dehydroepiandrosterone(DHEA), an adrenal androgen, has attracted much attention as an anti-aging hormone as well as a marker for senescence because of its unique change along with aging." | 4.93 | [Dehydroepiandrosterone(DHEA)and bone metabolism]. ( Ohnaka, K, 2016) |
| "Menopause has been chosen by evolution as the convergence of three factors, namely cessation of ovarian function (reproduction and estrogen secretion), high circulating dehydroepiandrosterone (DHEA), and intracrine enzymes able to convert DHEA into active sex steroids in peripheral tissues." | 4.89 | DHEA and intracrinology at menopause, a positive choice for evolution of the human species. ( Labrie, C; Labrie, F, 2013) |
| "The marked age-related decline in serum dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) has suggested that a deficiency of these steroids may be causally related to the development of a series of diseases that are generally associated with aging." | 4.86 | DHEA therapy in postmenopausal women: the need to move forward beyond the lack of evidence. ( Genazzani, AR; Pluchino, N, 2010) |
| " Hormones responsible for some of the manifestations associated with aging are growth hormone, insulin-like growth factor-1 (IGF-1), melatonin, dehydroepiandrosterone (DHEA), sex hormones and thyroid hormones." | 4.85 | [Hormone replacement therapy--growth hormone, melatonin, DHEA and sex hormones]. ( Akishita, M; Fukai, S, 2009) |
| "To present the possible positive effect of dehydroepiandrosterone administration in assisted reproduction and especially in poor responders, women with diminished ovarian reserve, premature ovarian failure and premature ovarian aging in the course of ovarian stimulation protocols followed either by intrauterine insemination or IVF." | 4.85 | Dehydroepiandrosterone supplementation in assisted reproduction: rationale and results. ( Mamas, E; Mamas, L, 2009) |
| "The hypothalamic-pituitary-adrenal axis activity in the aging people is characterised by an unexplained reduction of dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) secretion while ACTH and cortisol production remains relatively unchanged." | 4.84 | [Adrenopause]. ( Krysiak, R; Okopień, B; Szkróbka, W, 2008) |
| "The endocrine system of aging males reveals changes of more or less unknown significance for estrogens, dehydroepiandrosterone (DHEA), melatonin and growth hormone." | 4.82 | [Hormone therapy in the aging male. Estrogen, DHEA, melatonin, somatotropin]. ( Kliesch, S, 2004) |
| "A number of beneficial effects consisting in suppression or at least diminishing of degenerative changes associated with aging is ascribed to dehydroepiandrosterone (3 beta-hydroxy-5-androsten-17-one, DHEA) and its sulfate (DHEAS), in spite of the fact that it does not act as other hormonal steroids through its specific intracellular receptors." | 4.80 | [Dehydroepiandrosterone, "the youth hormone", in the light of recent findings]. ( Hampl, R; Stárka, L, 1998) |
| " Three hormonal systems show decreasing circulating hormone concentrations during normal aging: (i) estrogen (in menopause) and testosterone (in andropause), (ii) dehydroepiandrosterone and its sulphate (in adrenopause), and (iii) the growth hormone/insulin-like growth factor I axis (in somatopause)." | 4.79 | The endocrinology of aging. ( Lamberts, SW; van den Beld, AW; van der Lely, AJ, 1997) |
| "Almost every female classic galactosemia patient develops primary ovarian insufficiency (POI)." | 3.91 | Dehydroepiandrosterone supplementation attenuates ovarian ageing in a galactose-induced primary ovarian insufficiency rat model. ( Akouri, R; Demir, N; Erman, M; Gunduz, T; Ozekinci, M; Sozen, B, 2019) |
| "The aim of this study was to investigate the effects of aging on the central nervous system steroid and myelin basic protein (MBP) profiles." | 3.78 | The effects of aging on the central nervous system steroid profiles and myelin basic protein in rats. ( Cenesiz, S; Ciftci, G; Gultiken, ME; Karayigit, MO; Nisbet, C; Yarim, GF; Yarim, M, 2012) |
| "Human aging is characterized by a marked decrease in circulating levels of dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS), hormonal changes associated with cognitive decline." | 3.78 | Perimenopausal regulation of steroidogenesis in the nonhuman primate. ( Kohama, SG; Sorwell, KG; Urbanski, HF, 2012) |
| "Dehydroepiandrosterone (DHEA) is believed to exert, besides others, positive effects on the insulin resistance or its secretion and glucose metabolism." | 3.78 | Dehydroepiandrosterone in the type 1 diabetes mellitus. ( Duskova, M; Hill, M; Hruskovicova, H; Starka, L, 2012) |
| " The purpose of this study was to investigate the motor function, anxiety levels, depression-related emotional responses, attentional function and plasma levels of testosterone and dehydroepiandrosterone (DHEA) in SAMP10." | 3.76 | Depression-like behavior and reduced plasma testosterone levels in the senescence-accelerated mouse. ( Egashira, N; Fujiwara, M; Iwasaki, K; Koushi, E; Mishima, K; Oishi, R; Okuno, R; Shirakawa, A, 2010) |
| "A major achievement from 500 million years of evolution is the establishment of a high secretion rate of dehydroepiandrosterone (DHEA) by the human adrenal glands coupled with the indroduction of menopause which stops secretion of estrogens by the ovary." | 3.76 | DHEA, important source of sex steroids in men and even more in women. ( Labrie, F, 2010) |
| " Dehydroepiandrosterone (DHEA) is an over-the-counter dietary supplement used as an immunomodulating, anti-depressant, anti-aging, anti-cardiovascular disease, and anti-cancer agent and anti-obesity supplement." | 3.76 | Dehydroepiandrosterone intake protects against 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in the obese Zucker rat model. ( Hakkak, R; Jo, CH; Korourian, S; MacLeod, S; Shaaf, S, 2010) |
| "The aim of our study was to assess selected negative (transferrin) and positive (alpha1-antichymotrypsin [alpha1-ACT], C-reactive protein [CRP]) acute phase proteins, and to investigate associations between these proteins and serum dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) levels, as well as anthropometrical and biochemical indices of metabolic syndrome (MS) in men over 40 years of age." | 3.75 | Assessment of selected serum inflammatory markers of acute phase response and their correlations with adrenal androgens and metabolic syndrome in a population of men over the age of 40. ( Herman, WA; Korczowska, I; Lacka, K; Seńko, A, 2009) |
| "The aim of the present work was to analyze the effect of dehydroepiandrosterone (DHEA) on several metabolic risk factors, including cardiovascular health and insulin resistance, in aged rats submitted to a high-fat diet." | 3.74 | Adiponectin is involved in the protective effect of DHEA against metabolic risk in aged rats. ( Garaulet, M; Nicolás, F; Palou, A; Pérez-de-Heredia, F; Portillo, Mdel P; Priego, T; Sánchez, J; Zamora, S, 2008) |
| "To observe changes in the nitric oxide (NO) pathway and the interventional effects of dehydroepiandrosterone (DHEA) in the artery during the aging process." | 3.74 | Research on the age-related changes in the nitric oxide pathway in the arteries of rats and the intervention effect of dehydroepiandrosterone. ( Lai, W; Ruan, Y; Wu, S; Yin, M, 2007) |
| "Dehydroepiandrosterone (DHEA), one of the major steroid hormones, and its ester have recently received attention with regard to aging and age-related diseases like Alzheimer and others." | 3.74 | Effect of dehydroepiandrosterone (DHEA) on monoamine oxidase activity, lipid peroxidation and lipofuscin accumulation in aging rat brain regions. ( Baquer, NZ; Kale, RK; Kumar, P; Sharma, D; Taha, A, 2008) |
| " The aim of this study was to analyse the effect of chronic administration (13 weeks) of DHEA (5 g/kg diet) to old female rats fed on a high-fat diet on body weight and adiposity, and concretely on the expression of the adipokines related to obesity and insulin resistance, such as leptin, adiponectin and resistin." | 3.74 | Dehydroepiandrosterone prevents age-associated alterations, increasing insulin sensitivity. ( Garaulet, M; Palou, A; Pérez-Heredia, F; Portillo, MP; Priego, T; Sánchez, J; Zamora, S, 2008) |
| "Considering the results of the Massachusetts Male Aging Study (1994) we undertook the current investigation in an attempt to clarify the role of dehydroepiandrosterone sulphate (DHEAS), testosterone and lipids on age related deterioration of erectile function." | 3.73 | Are dehydroepiandrosterone sulphate and lipids associated with erectile dysfunction? ( Kumanov, P; Tomova, A, 2005) |
| "The goals of this study were to determine whether alterations in serum dehydroepiandrosterone (DHEA), its sulfated conjugate (DHEAS), androstenedione, testosterone, and progesterone concentrations occur in schizophrenia patients compared with healthy controls over two months, and their associations with psychopathology, emotional distress, and antipsychotic treatment." | 3.73 | Alterations in DHEA metabolism in schizophrenia: two-month case-control study. ( Gibel, A; Maayan, R; Ram, E; Ritsner, M; Weizman, A, 2006) |
| "A decline in dehydroepiandrosterone (DHEA) and GH levels with aging may be associated with frailty and morbidity." | 3.73 | Dehydroepiandrosterone restoration of growth hormone gene expression in aging female rats, in vivo and in vitro: evidence for actions via estrogen receptors. ( Childs, GV; Iruthayanathan, M; Zhou, YH, 2005) |
| "The content of the neurosteroids, dehydroepiandrosterone (DHEA) in the brain decreases with aging." | 3.73 | Treatment with dehydroepiandrosterone (DHEA) stimulates oxidative energy metabolism in the cerebral mitochondria. A comparative study of effects in old and young adult rats. ( Katyare, SS; Patel, MA, 2006) |
| "240 C57BL/6 mice were treated, from the age of 21 months until death, by normobaric hypoxia (11% FIO2) or normoxia, both with and without dehydroepiandrosterone sulfate (25 mg/kg in drinking water) (4 groups, N = 60)." | 3.73 | Hypoxia and dehydroepiandrosterone in old age: a mouse survival study. ( Baulieu, EE; Debonneuil, EH; Quillard, J, 2006) |
| "The influence of physical activity on dehydroepiandrosterone sulfate (DHEAS), total and free testosterone (TT and FT, respectively), insulin-like growth factor I (IGF-1), follicle-stimulating hormone (FSH), luteinizing hormone (LH) and insulin concentrations in aging men was investigated." | 3.71 | Testosterone, dehydroepiandrosterone, insulin-like growth factor 1, and insulin in sedentary and physically trained aged men. ( Fiet, J; Péres, G; Piette, F; Tissandier, O, 2001) |
| "The purpose of this study was to determine whether administration of dehydroepiandrosterone (DHEA) protects male rats against the accumulation of body fat the development of insulin resistance with advancing age." | 3.70 | DHEA treatment reduces fat accumulation and protects against insulin resistance in male rats. ( Chen, MM; Han, DH; Hansen, PA; Holloszy, JO, 1998) |
| " In these diseases or during aging, the decrease in production of sex hormones such as dehydroepiandrosterone (DHEA) is thought to play an important role in IL-6-mediated pathogenetic effects in mice." | 3.70 | Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man in vitro: possible link between endocrinosenescence and immunosenescence. ( Falk, W; Hrach, S; Konecna, L; Kreutz, M; Lang, B; Rothe, G; Schölmerich, J; Straub, RH, 1998) |
| " The aim of the present study was to assess serum allopregnanolone concentrations according to gender, menstrual cycle, age, and menopause in normal men and women; serum progesterone (P) and dehydroepiandrosterone (DHEA) levels were evaluated in the same specimens." | 3.70 | Circulating levels of allopregnanolone in humans: gender, age, and endocrine influences. ( Bernardi, F; Casarosa, E; Genazzani, AR; Luisi, M; Luisi, S; Nappi, RE; Palumbo, M; Petraglia, F; Purdy, RH; Salvestroni, C; Tonetti, A, 1998) |
| "To evaluate whether dehydroepiandrosterone (DHEA) ameliorates the decreased insulin sensitivity in older rats, hyperinsulinemic euglycemic clamp studies were performed in rats of various age groups previously treated with DHEA." | 3.70 | Dehydroepiandrosterone (DHEA) ameliorates the insulin sensitivity in older rats. ( Aoki, K; Kanesiro, M; Mukasa, K; Okamura, J; Saito, T; Satoh, S; Sekihara, H, 1998) |
| "Aging is associated with a selective decline in circulating levels of dehydroepiandrosterone (DHEA) and its sulfate, with no major changes in cortisol secretion." | 3.70 | Evaluation of the circadian profiles of serum dehydroepiandrosterone (DHEA), cortisol, and cortisol/DHEA molar ratio after a single oral administration of DHEA in elderly subjects. ( Ablondi, F; Banchini, A; Ceda, GP; Ceresini, G; Ferrari, E; Freddi, M; Morganti, S; Rebecchi, I; Solerte, SB; Valenti, G, 2000) |
| " Among these, we cite the problem of whether the age-related decrease in testosterone (T) levels is an intrinsic aging phenomenon or is a sequel of previous illness, the mechanisms underlying the increase in sex hormone-binding globulin (SHBG)-binding capacity in aging men and the supranormal capacity observed immediately after a weight-reducing diet, and the role of insulin in the age-associated decrease in dehydroepiandrosterone (sulfate) [DHEA (DHEAS)] levels." | 3.69 | Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males. ( Giagulli, VA; Kaufman, JM; Vermeulen, A, 1996) |
| "Dehydroepiandrosterone sulfate (DS) was measured by direct tritium RIA in longitudinal plasma specimens from 97 normal healthy male participants in the Baltimore Longitudinal Study of Aging." | 3.68 | Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men. ( Andres, R; Baldwin, H; Brind, JL; Orentreich, N; Vogelman, JH, 1992) |
| "In recent years, relationships of dehydroepiandrosterone and its sulfate ester dehydroepiandrosterone sulfate (DHEAS) with decreased risks of cardiovascular disease as well as a possible role in the aging process have been postulated." | 3.68 | Effects of age, smoking and vitamins on plasma DHEAS levels: a cross-sectional study in men. ( Barbieri, RL; Hennekens, CH; Salvini, S; Stampfer, MJ, 1992) |
| "It has been postulated that dehydroepiandrosterone (DHEA) and its sulfate ester, dehydroepiandrosterone sulfate (DHEAS), the major secretory products of the human adrenal gland, may be discriminators of life expectancy and aging." | 3.67 | A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease. ( Barrett-Connor, E; Khaw, KT; Yen, SS, 1986) |
| ", food restriction and chronic dehydroepiandrosterone (DHEA) treatment), or a production of obesity by the presence of the ob (obese) gene or by gold thioglucose-induced hyperphagia alter the rate of binding of 3H-7,12-dimethylbenz(a)anthracene (3H-DMBA) to mouse skin deoxyribonucleic acid (DNA)." | 3.66 | Effect of food restriction, dehydroepiandrosterone, or obesity on the binding of 3H-7,12-dimethylbenz(a)anthracene to mouse skin DNA. ( Pashko, LL; Schwartz, AG, 1983) |
| "Forty-seven patients with gout, 28 of whom had not previously been treated with allopurinol, and 25 normal subjects, were examined for 24-h urinary excretion of the most important adrenal steroid derivatives." | 3.66 | Hormonal aspects of human gout--excretion of adrenal hormone derivatives in gouty patients. ( Aleo, MF; Bianchi, E; Ferrari, S; Gregolini, L; Marcolongo, R; Marinello, E, 1983) |
| "During the human aging process, basal plasma levels of cortisol and aldosterone demonstrate little change, while concentrations of adrenal androgens (AA) such as dehydroepiandrosterone (DHA), dehydroepiandrosterone sulfate (DHAS), and androstenedione (A) decrease dramatically in men and women." | 3.66 | Decreased adrenal androgen sensitivity to ACTH during aging. ( Gral, T; Parker, L; Perrigo, V; Skowksy, R, 1981) |
| "Dehydroepiandrosterone (DHEA) is a steroid that shows a marked age-related decline in humans." | 2.70 | Salivary cortisol and DHEA: association with measures of cognition and well-being in normal older men, and effects of three months of DHEA supplementation. ( Herbert, J; Huppert, FA; van Niekerk, JK, 2001) |
| " The responsiveness of the steroids of interest to ACTH (defined as the slope of the dose-response curve over the linear portion of the dose-response curve) also was similar among younger and older women." | 2.69 | Effects of aging on adrenal function in the human: responsiveness and sensitivity of adrenal androgens and cortisol to adrenocorticotropin in premenopausal and postmenopausal women. ( Azziz, R; Bae, S; Boots, LR; Crabbe, SL; Hines, GA; Parker, CR; Slayden, SM, 2000) |
| "Dehydroepiandrosterone was lowered at 8:00 AM and 8:00 PM compared with control subjects." | 2.69 | Altered salivary dehydroepiandrosterone levels in major depression in adults. ( Herbert, J; Jenaway, A; Michael, A; Paykel, ES, 2000) |
| "Benfluorex treatment lowered diastolic and systolic blood pressures and improved glucose tolerance in both age groups." | 2.68 | Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men. ( Beer, NA; Beer, RM; Colombo, C; Jakubowicz, DJ; Nestler, JE, 1995) |
| " Only mice immunized shortly after oral dosing with DHEAS demonstrated high serum antibody titers and complete protection from paralysis." | 2.68 | DHEAS as an effective vaccine adjuvant in elderly humans. Proof-of-principle studies. ( Araneo, B; Daynes, R; Dowell, T; Evans, T; Judd, M; Woods, ML, 1995) |
| "Dehydroepiandrosterone (DHEA) is a native steroid with an immunomodulating activity that was suggested to counter-regulate some phenomena of immunosenescence." | 2.68 | Dehydroepiandrosterone treatment is not beneficial to the immune response to influenza in elderly subjects. ( Ben-Yehuda, A; Danenberg, HD; Friedman, G; Gross, DJ; Zakay-Rones, Z, 1997) |
| " Overreliance on animal models (DHEA is essentially a human molecule), different dosing protocols with non-pharmacological doses often unachievable in humans, rapid metabolism of DHEA, co-morbidities and organ-specific differences render data interpretation difficult." | 2.50 | Dehydroepiandrosterone (DHEA): hypes and hopes. ( Kuryliszyn-Moskal, A; Rutkowska-Talipska, J; Rutkowski, K; Rutkowski, R; Sowa, P, 2014) |
| "Dehydroepiandrosterone (DHEA) is a C19 steroid of adrenal origin." | 2.46 | Dehydroepiandrosterone as a regulator of immune cell function. ( Arlt, W; Hazeldine, J; Lord, JM, 2010) |
| "Dehydroepiandrosterone replacement in hypoadrenalism modestly improved insulin sensitivity and altered the lipid profile, but it remains uncertain whether these changes improve any patient-important outcomes." | 2.44 | Dehydroepiandrosterone in adrenal insufficiency and ageing. ( Bhagra, S; Nair, KS; Nippoldt, TB, 2008) |
| "Type 2 diabetes mellitus is increasing globally and is an established risk factor for the development of atherosclerotic vascular disease." | 2.43 | Androgens, insulin resistance and vascular disease in men. ( Channer, KS; Jones, TH; Kapoor, D; Malkin, CJ, 2005) |
| "Dehydroepiandrosterone (DHEA) is an abundant circulating androgen precursor preferentially produced by the adrenal glands." | 2.43 | Dehydroepiandrosterone therapy as female androgen replacement. ( Guay, A; Saltzman, E, 2006) |
| " This paper includes practical considerations on dosage to be used, contraindications and follow-up." | 2.42 | Androgen therapy with dehydroepiandrosterone. ( Buvat, J, 2003) |
| " We don't know the possible negative consequences of long-term administration of DHEA\\DHEAS on cardiovascular disease and hormone-dependent cancers." | 2.42 | [DHEA and aging]. ( Pitti-Ferrandi, H, 2003) |
| "Obesity is an issue that is increasingly affecting ageing men." | 2.41 | Impact of obesity on hypogonadism in the andropause. ( Pu, SJ; Tan, RS, 2002) |
| "Future research should focus on DHEA treatment for adrenal insufficiency, and DHEA administration in both patients receiving chronic glucocorticoid treatment and women with androgen deficiency." | 2.41 | DHEA treatment: myth or reality? ( Allolio, B; Arlt, W, 2002) |
| "Dehydroepiandrosterone (DHEA) is a steroid secreted by the adrenal cortex, with a characteristic, age-related, pattern of secretion." | 2.40 | DHEA deficiency syndrome: a new term for old age? ( Hinson, JP; Raven, PW, 1999) |
| "We advance the hypothesis that hyperinsulinemia promotes macrovascular disease in part by reducing serum DHEA and DHEA-sulfate levels and illustrate how this may be the case in two clinical conditions characterized by hyperinsulinemic insulin resistance: aging and obesity." | 2.38 | Dehydroepiandrosterone: the "missing link" between hyperinsulinemia and atherosclerosis? ( Blackard, WG; Clore, JN; Nestler, JE, 1992) |
| "Corticosterone was measured by radioimmunoassay and DHEA by ELISA." | 1.91 | Developmental Programming-Aging Interactions Have Sex-Specific and Developmental Stage of Exposure Outcomes on Life Course Circulating Corticosterone and Dehydroepiandrosterone (DHEA) Concentrations in Rats Exposed to Maternal Protein-Restricted Diets. ( Chavira, R; Gerow, KG; Lomas-Soria, C; Nathanielsz, PW; Reyes-Castro, LA; Rodríguez-González, GL; Zambrano, E, 2023) |
| "Dehydroepiandrosterone (DHEA) is an important precursor of active steroid hormone, produced abundantly by the adrenal cortex with an age-dependent pattern." | 1.48 | DHEA Treatment Effects on Redox Environment in Skeletal Muscle of Young and Aged Healthy Rats. ( Belló-Klein, A; Bonetto, JHP; da R Araujo, AS; Fernandes, RO; Jacob, MHVM; Mendes, RH; Ribeiro, MFM, 2018) |
| "Approximately 70% of breast cancers are diagnosed in postmenopausal women." | 1.40 | The role of hormones and aromatase inhibitors on breast tumor growth and general health in a postmenopausal mouse model. ( Arumugam, A; Lakshmanaswamy, R; Lissner, EA, 2014) |
| " Randomized trials in elderly subjects with an age-dependent decrease in DHEA have provided little or no evidence for enhanced physical performance after long-term administration of DHEA, 50 mg/d, and smaller short-term studies in healthy male athletes using higher doses were completely negative." | 1.36 | Dehydroepiandrosterone to enhance physical performance: myth and reality. ( Allolio, B; Hahner, S, 2010) |
| "Dehydroepiandrosterone (DHEA) is a steroid synthesized in adrenal cortex as well as in the nervous system." | 1.36 | Dehydroepiandrosterone effects on Akt signaling modulation in central nervous system of young and aged healthy rats. ( Jacob, MH; Jahn, MP; Janner, Dda R; Kucharski, LC; Ribeiro, MF, 2010) |
| "Dehydroepiandrosterone (DHEA) is a ubiquitous adrenal hormone with immunomodulatory properties whose levels decline significantly with advanced age in humans." | 1.33 | The sex steroid precursor DHEA accelerates cutaneous wound healing via the estrogen receptors. ( Ashcroft, GS; Ashworth, JJ; Gilliver, SC; Hardman, MJ; Mills, SJ, 2005) |
| " In cases of inadequate dosage there were side effects like sleepiness,restlessness, headache, acne/hirsutism, effluvium or odors in a percentage of 34, 17, 9, 31, 21 and 11% of the women, respectively." | 1.32 | [Adrenopause and dehydroepiandrosterone: pharmacological therapy versus replacement therapy]. ( Römmler, A, 2003) |
| "In addition, among the PTSD subjects, the peak change in DHEA in response to ACTH1-24 was negatively correlated with the total Clinician Administered PTSD Scale score, while the peak DHEA to cortisol ratio was inversely associated with negative mood symptoms measured by the Profile of Mood States scale." | 1.32 | An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD. ( Charney, DS; Gudmundsen, G; Lipschitz, DS; Morgan, CA; Mustone, ME; Rasmusson, AM; Shi, Q; Vasek, J; Vojvoda, D; Wolfe, J, 2004) |
| " DHEA or DHEA-S have been administered acutely in a single intraperitoneal injection at a dosage of 50, 250, or 500 microg per animal, or on a long-term basis, i." | 1.32 | Ex vivo studies on the acute and chronic effects of DHEA and DHEA-sulfate on melatonin synthesis in young- and old-rat pineal glands. ( Djeridane, Y; Touitou, Y, 2004) |
| " Therefore, the bioavailability of estradiol in the oldest men was likely diminished." | 1.32 | Testicular and blood steroid levels in aged men. ( Bourguiba, S; Carreau, S; Marie, E, 2004) |
| "Dehydroepiandrosterone (DHEA) is an adrenal androgen whose function is poorly understood." | 1.31 | Characterization of serum dehydroepiandrosterone secretion in golden hamsters. ( Lobocki, CA; Pieper, DR, 2000) |
| "Melatonin is a hormone secreted by the pineal gland, the releasing stimulus of which is darkness." | 1.30 | [Juvenile hormones, reality or myth?]. ( Vermeulen, A, 1997) |
| "Dehydroepiandrosterone was positively associated with BMD of the midradius, spine, and hip in women and was not associated with BMD at any site in men." | 1.30 | Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo Study. ( Barrett-Connor, E; Edelstein, S; Greendale, GA, 1997) |
| "Dehydroepiandrosterone (DHEA) has an antiobesity effect in rodents, and elevated endogenous levels of its sulfate ester (DHEAS) are associated with reductions in risk for cardiovascular disease (CVD) in men." | 1.29 | Relationship of body fat percentage and fat distribution with dehydroepiandrosterone sulfate in premenopausal females. ( Boyden, TW; Going, SB; Lohman, TG; Pamenter, RW; Williams, DP, 1993) |
| "Dehydroepiandrosterone (DHEA) is a native steroid with an immunomodulating activity." | 1.29 | Dehydroepiandrosterone (DHEA) treatment reverses the impaired immune response of old mice to influenza vaccination and protects from influenza infection. ( Ben-Yehuda, A; Danenberg, HD; Friedman, G; Zakay-Rones, Z, 1995) |
| "DHEA's background and use as an AIDS treatment are reviewed." | 1.29 | DHEA and AIDS. ( James, JS, 1996) |
| "The incidence of spontaneous Leydig cell tumors of testis is very high in old F-344 rats." | 1.28 | Inhibition of spontaneous testicular Leydig cell tumor development in F-344 rats by dehydroepiandrosterone. ( Rao, MS; Reddy, JK; Subbarao, V; Yeldandi, AV, 1992) |
| "Dehydroepiandrosterone (DHEA) is an immunomodulator that has been demonstrated to upregulate immune parameters." | 1.28 | Dehydroepiandrosterone-induced reduction of Cryptosporidium parvum infections in aged Syrian golden hamsters. ( Healey, MC; Rasmussen, KR, 1992) |
| "Dehydroepiandrosterone (DHEA) was fed at 0." | 1.27 | Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice. ( Coleman, DL; Leiter, EH; Schwizer, RW, 1984) |
| "Dehydroepiandrosterone (DHEA) is an adrenal steroid that previously has been shown to produce antiobesity, antidiabetic, cancer preventive, and antiautoimmune effects in laboratory rodents." | 1.27 | Inhibition of proteinuria development in aging Sprague-Dawley rats and C57BL/6 mice by long-term treatment with dehydroepiandrosterone. ( Fairman, DK; Pashko, LL; Schwartz, AG, 1986) |
| "Nineteen patients had idiopathic precocious puberty and 8 had organic lesions (hamartoma, hydrocephalus or suprasellar arachnoid cyst)." | 1.27 | Treatment of central precocious puberty with an LHRH agonist (Buserelin): effect on growth and bone maturation after three years of treatment. ( Brauner, R; Fontoura, M; Rappaport, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 93 (17.13) | 18.7374 |
| 1990's | 155 (28.55) | 18.2507 |
| 2000's | 201 (37.02) | 29.6817 |
| 2010's | 81 (14.92) | 24.3611 |
| 2020's | 13 (2.39) | 2.80 |
| Authors | Studies |
|---|---|
| Zouhal, H | 1 |
| Jayavel, A | 1 |
| Parasuraman, K | 1 |
| Hayes, LD | 1 |
| Tourny, C | 1 |
| Rhibi, F | 1 |
| Laher, I | 1 |
| Abderrahman, AB | 1 |
| Hackney, AC | 1 |
| Stamou, MI | 1 |
| Colling, C | 1 |
| Dichtel, LE | 1 |
| Grandys, M | 1 |
| Majerczak, J | 1 |
| Frolow, M | 1 |
| Sztefko, K | 1 |
| Chlopicki, S | 1 |
| Zoladz, JA | 1 |
| Lee, WJ | 1 |
| Peng, LN | 1 |
| Lin, MH | 1 |
| Loh, CH | 1 |
| Hsiao, FY | 1 |
| Chen, LK | 1 |
| Zambrano, E | 2 |
| Reyes-Castro, LA | 1 |
| Rodríguez-González, GL | 1 |
| Chavira, R | 1 |
| Lomas-Soria, C | 1 |
| Gerow, KG | 1 |
| Nathanielsz, PW | 1 |
| Burns, BR | 1 |
| Davis, SR | 1 |
| Bell, RJ | 1 |
| Robinson, PJ | 1 |
| Handelsman, DJ | 1 |
| Gilbert, T | 1 |
| Phung, J | 1 |
| Desai, R | 1 |
| Lockery, JE | 1 |
| Woods, RL | 1 |
| Wolfe, RS | 1 |
| Reid, CM | 1 |
| Nelson, MR | 1 |
| Murray, AM | 1 |
| McNeil, JJ | 1 |
| Sozen, B | 1 |
| Ozekinci, M | 1 |
| Erman, M | 1 |
| Gunduz, T | 1 |
| Demir, N | 1 |
| Akouri, R | 1 |
| Teixeira, CJ | 1 |
| Veras, K | 1 |
| de Oliveira Carvalho, CR | 1 |
| Huang, K | 1 |
| Cai, HL | 1 |
| Bao, JP | 1 |
| Wu, LD | 1 |
| Luna, SL | 1 |
| Brown, DI | 1 |
| Kohama, SG | 3 |
| Urbanski, HF | 5 |
| Yeap, BB | 1 |
| Dwivedi, G | 1 |
| Farzane, A | 1 |
| Koushkie Jahromi, M | 1 |
| Li, CJ | 2 |
| Lin, LT | 2 |
| Tsui, KH | 2 |
| Sharma, R | 1 |
| Sharma, A | 1 |
| Kumari, A | 1 |
| Kulurkar, PM | 1 |
| Raj, R | 1 |
| Gulati, A | 1 |
| Padwad, YS | 1 |
| Chu, N | 1 |
| Gui, Y | 1 |
| Qiu, X | 1 |
| Zhang, N | 1 |
| Li, L | 1 |
| Li, D | 1 |
| Tang, W | 1 |
| Gober, HJ | 1 |
| Zhang, B | 1 |
| Wang, L | 1 |
| Williams, BR | 1 |
| Cho, JS | 1 |
| Cheng, JT | 1 |
| Wang, PH | 1 |
| Narkwichean, A | 1 |
| Maalouf, W | 1 |
| Baumgarten, M | 1 |
| Polanski, L | 1 |
| Raine-Fenning, N | 1 |
| Campbell, B | 1 |
| Jayaprakasan, K | 1 |
| Jiménez-Rubio, G | 2 |
| Herrera-Pérez, JJ | 2 |
| Hernández-Hernández, OT | 1 |
| Martínez-Mota, L | 2 |
| Hauray, B | 1 |
| Dalgalarrondo, S | 1 |
| Jacob, MHVM | 1 |
| Fernandes, RO | 1 |
| Bonetto, JHP | 1 |
| Mendes, RH | 1 |
| da R Araujo, AS | 1 |
| Belló-Klein, A | 3 |
| Ribeiro, MFM | 1 |
| Powrie, YSL | 1 |
| Smith, C | 1 |
| Giannini, A | 1 |
| Caretto, M | 1 |
| Genazzani, AR | 12 |
| Simoncini, T | 1 |
| Harada, K | 1 |
| Hanayama, Y | 1 |
| Obika, M | 1 |
| Itoshima, K | 1 |
| Okada, K | 1 |
| Otsuka, F | 1 |
| Conley, AJ | 1 |
| Stanczyk, FZ | 1 |
| Morrison, JH | 1 |
| Borowicz, P | 1 |
| Benirschke, K | 1 |
| Gee, NA | 1 |
| Lasley, BL | 1 |
| Samaras, N | 3 |
| Samaras, D | 3 |
| Frangos, E | 2 |
| Forster, A | 2 |
| Philippe, J | 2 |
| Fenton, A | 1 |
| Panay, N | 1 |
| Sorwell, KG | 3 |
| Nguyen, TV | 1 |
| McCracken, JT | 1 |
| Ducharme, S | 1 |
| Cropp, BF | 1 |
| Botteron, KN | 1 |
| Evans, AC | 1 |
| Karama, S | 1 |
| Pluchino, N | 6 |
| Santoro, A | 2 |
| Casarosa, E | 4 |
| Wenger, JM | 1 |
| Genazzani, AD | 4 |
| Petignat, P | 1 |
| Carmignani, A | 1 |
| Cubeddu, A | 1 |
| Cela, V | 1 |
| Errasti, T | 1 |
| Alcalà, TE | 1 |
| Heaney, JL | 2 |
| Carroll, D | 3 |
| Phillips, AC | 3 |
| Ford, JH | 1 |
| Sato, K | 1 |
| Iemitsu, M | 1 |
| Matsutani, K | 1 |
| Kurihara, T | 1 |
| Hamaoka, T | 1 |
| Fujita, S | 1 |
| Collomp, K | 1 |
| Buisson, C | 1 |
| Lasne, F | 1 |
| Collomp, R | 1 |
| Prati, A | 1 |
| Santagni, S | 1 |
| Rattighieri, E | 1 |
| Campedelli, A | 1 |
| Ricchieri, F | 1 |
| Chierchia, E | 1 |
| Despini, G | 1 |
| Rutkowski, K | 1 |
| Sowa, P | 1 |
| Rutkowska-Talipska, J | 1 |
| Kuryliszyn-Moskal, A | 1 |
| Rutkowski, R | 1 |
| Arumugam, A | 1 |
| Lissner, EA | 1 |
| Lakshmanaswamy, R | 1 |
| Papadopoulou, MA | 1 |
| Ongaro, F | 1 |
| Racaru-Honciuc, V | 1 |
| Betea, D | 1 |
| Scheen, AJ | 1 |
| Elraiyah, T | 1 |
| Sonbol, MB | 1 |
| Wang, Z | 1 |
| Khairalseed, T | 1 |
| Asi, N | 1 |
| Undavalli, C | 1 |
| Nabhan, M | 1 |
| Altayar, O | 1 |
| Prokop, L | 1 |
| Montori, VM | 1 |
| Murad, MH | 1 |
| Grimm, A | 1 |
| Schmitt, K | 1 |
| Lang, UE | 1 |
| Mensah-Nyagan, AG | 1 |
| Eckert, A | 1 |
| Kozloski, MJ | 1 |
| Schumm, LP | 1 |
| McClintock, MK | 1 |
| Pukhal'skiĭ, AL | 1 |
| Shmarina, GV | 1 |
| Aleshkin, VA | 1 |
| Eden, JA | 1 |
| Thilagam, A | 1 |
| Rabijewski, M | 1 |
| Papierska, L | 1 |
| Kuczerowski, R | 1 |
| Piątkiewicz, P | 1 |
| Yin, FJ | 1 |
| Kang, J | 1 |
| Han, NN | 1 |
| Ma, HT | 1 |
| Al-Turk, W | 1 |
| Al-Dujaili, EA | 1 |
| Ohnaka, K | 2 |
| Rendina, DN | 1 |
| Ryff, CD | 1 |
| Coe, CL | 1 |
| Vitale, G | 1 |
| Cesari, M | 1 |
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| Philipp, M | 1 |
| Lozza, N | 1 |
| Ehlert, U | 1 |
| Lettieri-Barbato, D | 1 |
| Giovannetti, E | 1 |
| Aquilano, K | 1 |
| Ortiz-López, L | 1 |
| Cabrera-Muñoz, EA | 1 |
| Galindo-Sevilla, N | 1 |
| Hernández-Luis, F | 1 |
| Ramírez-Rodríguez, GB | 1 |
| Flores-Ramos, M | 1 |
| Diamanti-Kandarakis, E | 1 |
| Dattilo, M | 1 |
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| Hazeldine, J | 1 |
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| Labrie, F | 6 |
| Hakkak, R | 1 |
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| Straub, RH | 2 |
| Seriolo, B | 1 |
| Tan, RS | 2 |
| Pu, SJ | 1 |
| Corrigan, B | 1 |
| Bourguignon, R | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antioxidants vs.Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve[NCT03621683] | 78 participants (Actual) | Interventional | 2016-01-06 | Completed | |||
| The Use of DHEA in Women With Premature Ovarian Failure[NCT01129947] | Early Phase 1 | 0 participants (Actual) | Interventional | 2010-05-31 | Withdrawn (stopped due to very poor patient recruitement) | ||
| Effect of Dehydroepiandrosterone on Live Birth Rate in Subfertile Patients With Poor Ovarian Responds[NCT02432248] | 350 participants (Anticipated) | Interventional | 2015-02-28 | Recruiting | |||
| DHEA + Acolbifene Against Vasomotor Symptoms (Hot Flushes) in Postmenopausal Women (Placebo Controlled, Double Blind and Randomized Phase III Study to Evaluate the Effects of 12-Week Treatment With DHEA (Prasterone) and Acolbifene on Vasomotor Symptoms (H[NCT01452373] | Phase 3 | 238 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| Fatigability and Physical Performance: Effects of Resistance Training Variables Manipulation[NCT03619070] | 80 participants (Anticipated) | Interventional | 2018-05-20 | Recruiting | |||
| Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women.[NCT00248989] | Phase 3 | 150 participants (Actual) | Interventional | 2004-11-01 | Completed | ||
| Biological Effects of DHEA in the Elderly[NCT00111930] | 144 participants | Interventional | 2000-08-31 | Completed | |||
| Efficacy and Safety of Pregnenolone Augmentation in the Management of Schizophrenia Patients: a Randomised Double-Blind Placebo-Controlled Trial[NCT00174889] | Phase 1 | 60 participants | Interventional | 2005-01-31 | Completed | ||
| The Role of Dehydroepiandrosterone in the Maintenance of Mitochondrial Quality of Cumulus Cells in Poor Ovarian Responders[NCT03438812] | 66 participants (Actual) | Interventional | 2017-09-06 | Completed | |||
| Pathogenesis of Sarcopenia and Metabolic Changes in Aging[NCT00254371] | 150 participants | Interventional | 1998-07-31 | Completed | |||
| Dehydroepiandrosterone Treatment of Mid-Life-Related Mood Disorders in Women and Men[NCT00001487] | Phase 2 | 60 participants | Interventional | 1995-06-30 | Completed | ||
| Factors Associated With Obesity in Adult Women: Respiratory Exchange Ratio, Heart Rate Variation and Body Image[NCT04029532] | 121 participants (Actual) | Observational | 2019-04-01 | Completed | |||
| The Effects of Testosterone and Nutritional Supplementation, Alone and Combined, on the Adverse Effects of Under-Nutrition in the Elderly[NCT00117000] | Phase 3 | 200 participants | Interventional | 2003-07-31 | Active, not recruiting | ||
| Diabetes and Cardiovascular Risk In Mexico City (San Antonio Heart Study)[NCT00005146] | 0 participants | Observational | 1979-05-31 | Completed | |||
| Aromatase Activity and Ovarian Growth Factors in Preovulatory Follicles[NCT00334971] | 116 participants (Anticipated) | Interventional | 2004-09-30 | Active, not recruiting | |||
| Phase II-III Placebo-Controlled, Study to Evaluate the Effects of DHEA on Vasomotor Symptoms (Hot Flashes) in Postmenopausal Women[NCT00317148] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2005-08-31 | Completed | ||
| Biologic Effects of DHEA in Humans[NCT00099697] | 56 participants | Interventional | 2001-06-30 | Completed | |||
| Is DHEA Replacement Beneficial?[NCT00182975] | Phase 3 | 142 participants (Actual) | Interventional | 2002-09-30 | Completed | ||
| Effects of Omega-3 Fatty Acids on Bone and Frailty[NCT00634686] | Phase 4 | 150 participants (Anticipated) | Interventional | 2007-01-31 | Active, not recruiting | ||
| Allosteric Regulation of Cytosolic Sulfotransferases in Humans[NCT03383133] | Early Phase 1 | 1 participants (Actual) | Interventional | 2018-01-11 | Completed | ||
| [NCT00000500] | Phase 3 | 0 participants | Interventional | 1981-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
172 reviews available for dehydroepiandrosterone and Aging
| Article | Year |
|---|---|
Effects of Exercise Training on Anabolic and Catabolic Hormones with Advanced Age: A Systematic Review.
Topics: Adult; Aged; Aging; Dehydroepiandrosterone; Exercise; Female; Hormones; Humans; Hydrocortisone; Insu | 2022 |
Adrenal aging and its effects on the stress response and immunosenescence.
Topics: Adrenal Cortex Hormones; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydr | 2023 |
Dehydroepiandrosterone on metabolism and the cardiovascular system in the postmenopausal period.
Topics: Aged; Aged, 80 and over; Aging; Animals; Cardiovascular Diseases; Cardiovascular System; Dehydroepia | 2020 |
Dehydroepiandrosterone and age-related musculoskeletal diseases: Connections and therapeutic implications.
Topics: Aged; Aging; Dehydroepiandrosterone; Humans; Musculoskeletal Diseases; Osteoporosis; Sarcopenia | 2020 |
Hormone Replacement: The Fountain of Youth?
Topics: Aged; Aging; Dehydroepiandrosterone; Estrogen Replacement Therapy; Hormone Replacement Therapy; Huma | 2017 |
Relationship between androgen deficiency and memory impairment in aging and Alzheimer’s disease.
Topics: Aged; Aging; Alzheimer Disease; Dehydroepiandrosterone; Humans; Memory Disorders; Testosterone | 2017 |
Central intracrine DHEA synthesis in ageing-related neuroinflammation and neurodegeneration: therapeutic potential?
Topics: Aging; Animals; Dehydroepiandrosterone; Encephalitis; Humans; Neurodegenerative Diseases | 2018 |
Optimizing quality of life through sex steroids by their effects on neurotransmitters.
Topics: Aging; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; Humans; Menopause; Nervous System P | 2019 |
A review of age-related dehydroepiandrosterone decline and its association with well-known geriatric syndromes: is treatment beneficial?
Topics: Aging; Dehydroepiandrosterone; Humans; Syndrome | 2013 |
Causes and consequences of age-related steroid hormone changes: insights gained from nonhuman primates.
Topics: Aging; Animals; Brain; Circadian Rhythm; Dehydroepiandrosterone; Estradiol; Macaca mulatta; Testoste | 2013 |
Advances in neurosteroids: role in clinical practice.
Topics: Affect; Aging; Behavior; Brain Injuries; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone S | 2013 |
Androgen therapy in women: for whom and when.
Topics: Aging; Androgens; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; Humans; Hypogonadism; | 2013 |
Reduced quality and accelerated follicle loss with female reproductive aging - does decline in theca dehydroepiandrosterone (DHEA) underlie the problem?
Topics: Aging; Androstenedione; Animals; Dehydroepiandrosterone; Female; Humans; Ovarian Follicle; Ovulation | 2013 |
DHEA, physical exercise and doping.
Topics: Age Factors; Aging; Athletes; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dietary Supple | 2015 |
[The putative role and use of DHEA and its association with the hormone replacement therapy].
Topics: Aging; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; Humans; Menopause | 2014 |
Dehydroepiandrosterone (DHEA): hypes and hopes.
Topics: Adrenal Insufficiency; Aging; Animals; Bone Density; Dehydroepiandrosterone; Dietary Supplements; Hu | 2014 |
Off-label use of hormones as an antiaging strategy: a review.
Topics: Aging; Dehydroepiandrosterone; Estrogens; Hormone Replacement Therapy; Human Growth Hormone; Humans; | 2014 |
Clinical review: The benefits and harms of systemic dehydroepiandrosterone (DHEA) in postmenopausal women with normal adrenal function: a systematic review and meta-analysis.
Topics: Adjuvants, Immunologic; Adrenal Glands; Aging; Dehydroepiandrosterone; Female; Humans; Middle Aged; | 2014 |
[Age related dehydroepiandrosterone decrease: clinical significance and therapeutic interest].
Topics: Adrenal Insufficiency; Aging; Dehydroepiandrosterone; Down-Regulation; Humans | 2015 |
[Dehydroepiandrosterone(DHEA)and bone metabolism].
Topics: Aging; Bone and Bones; Bone Density; Dehydroepiandrosterone; Hormone Replacement Therapy; Humans; Os | 2016 |
Aging of the endocrine system and its potential impact on sarcopenia.
Topics: Aged; Aging; Dehydroepiandrosterone; Endocrine System; Hormone Replacement Therapy; Humans; Muscle, | 2016 |
Effects of dietary restriction on adipose mass and biomarkers of healthy aging in human.
Topics: Adipokines; Adipose Tissue; Aging; Biomarkers; Caloric Restriction; Cytokines; Dehydroepiandrosteron | 2016 |
MECHANISMS IN ENDOCRINOLOGY: Aging and anti-aging: a Combo-Endocrinology overview.
Topics: Adjuvants, Immunologic; Aging; Androgens; Antioxidants; Circadian Rhythm; Dehydroepiandrosterone; Di | 2017 |
[Current views on the role of dehydroepiandrosterone in physiology, pathology and therapy].
Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenarche; Aged; Aging; Atherosclerosis; Cardiovascular Sys | 2008 |
[Adrenopause].
Topics: Adolescent; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Aging; Androgens; Ather | 2008 |
Chronic stress and immunosenescence: a review.
Topics: Aged; Aged, 80 and over; Aging; Aging, Premature; Caregivers; Chronic Disease; Circadian Rhythm; Cyt | 2008 |
Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS).
Topics: Adult; Aged; Aging; Animals; Antioxidants; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sul | 2009 |
The role of stress factors during aging of the immune system.
Topics: Aging; Dehydroepiandrosterone; Glucocorticoids; Growth Hormone; Humans; Immune System; Stress, Psych | 2009 |
[Dehydroepiandrosterone (DHEA), review of its efficiency in the managing of the libido decrease and other symtoms of aging].
Topics: Aging; Dehydroepiandrosterone; Female; Humans; Libido; Male; Middle Aged | 2009 |
[Hormone replacement therapy--growth hormone, melatonin, DHEA and sex hormones].
Topics: Aging; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; Growth Hormone; Hormone Replacement | 2009 |
Dehydroepiandrosterone supplementation in assisted reproduction: rationale and results.
Topics: Age Factors; Aging; Dehydroepiandrosterone; Female; Fertility Agents, Female; Humans; Infertility, F | 2009 |
Dehydroepiandrosterone supplementation in assisted reproduction: rationale and results.
Topics: Age Factors; Aging; Dehydroepiandrosterone; Female; Fertility Agents, Female; Humans; Infertility, F | 2009 |
Dehydroepiandrosterone supplementation in assisted reproduction: rationale and results.
Topics: Age Factors; Aging; Dehydroepiandrosterone; Female; Fertility Agents, Female; Humans; Infertility, F | 2009 |
Dehydroepiandrosterone supplementation in assisted reproduction: rationale and results.
Topics: Age Factors; Aging; Dehydroepiandrosterone; Female; Fertility Agents, Female; Humans; Infertility, F | 2009 |
Androgen replacement therapy and cardiovascular function.
Topics: Aging; Androgens; Cardiovascular Diseases; Cardiovascular System; Dehydroepiandrosterone; Female; Hu | 2009 |
Dehydroepiandrosterone as a regulator of immune cell function.
Topics: Aging; Animals; Dehydroepiandrosterone; Humans; Leukocytes; Lupus Erythematosus, Systemic; Lymphoid | 2010 |
DHEA therapy in postmenopausal women: the need to move forward beyond the lack of evidence.
Topics: Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hormone Replacement Therapy; | 2010 |
Neuroinflammation and ageing: current theories and an overview of the data.
Topics: Aging; Alzheimer Disease; Apoptosis; Atherosclerosis; Biological Evolution; Brain; Cellular Senescen | 2011 |
[Dehydroepiandrosterone [DHEA(S)]: anabolic hormone?].
Topics: Aging; Body Composition; Dehydroepiandrosterone; Female; Hormones; Humans; Male | 2010 |
Endocrinology of the aging male.
Topics: Aging; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Follicle Stimulating Hormone; Humans; H | 2011 |
Dehydroepiandrosterone (DHEA)--a precursor steroid or an active hormone in human physiology.
Topics: Aging; Animals; Body Composition; Bone and Bones; Cardiovascular Diseases; Dehydroepiandrosterone; D | 2011 |
Ovarian aging and implications for fertility female health.
Topics: Adult; Aging; Dehydroepiandrosterone; Diagnostic Techniques, Obstetrical and Gynecological; Female; | 2012 |
DHEA and intracrinology at menopause, a positive choice for evolution of the human species.
Topics: Adult; Age Factors; Aging; Androgens; Biological Evolution; Dehydroepiandrosterone; Endometrium; Est | 2013 |
Psychoneuroendocrine interventions aimed at attenuating immunosenescence: a review.
Topics: Aging; Aging, Premature; Dehydroepiandrosterone; Female; Ghrelin; Human Growth Hormone; Humans; Male | 2013 |
Impact of obesity on hypogonadism in the andropause.
Topics: Aged; Aging; Body Composition; Climacteric; Dehydroepiandrosterone; Diabetes Mellitus; Humans; Hypog | 2002 |
DHEA and sport.
Topics: Adjuvants, Immunologic; Aging; Cardiovascular Diseases; Dehydroepiandrosterone; Exercise; Female; Hu | 2002 |
DHEA treatment: myth or reality?
Topics: Adrenal Insufficiency; Affect; Aged; Aging; Animals; Body Composition; Dehydroepiandrosterone; Dehyd | 2002 |
Role of hormones in the pathogenesis and management of sarcopenia.
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Estrogens; Female; Gonadal Steroid Hormones; | 2002 |
Replacement therapy in the aging male.
Topics: Aging; Dehydroepiandrosterone; Growth Hormone; Hormone Replacement Therapy; Humans; Male; Melatonin | 2002 |
Androgens and aging men.
Topics: Aging; Androgens; Bone Density; Dehydroepiandrosterone; Estradiol; Female; Humans; Libido; Male; Men | 2002 |
Dehydroepiandrosterone (DHEA) and the aging brain: flipping a coin in the "fountain of youth".
Topics: Administration, Oral; Adrenal Cortex; Aged; Aging; Animals; Central Nervous System; Cognition; Cytoc | 2003 |
[DHEA: desire and resistance].
Topics: Aged; Aging; Breast Neoplasms; Dehydroepiandrosterone; Erectile Dysfunction; Female; Humans; Libido; | 2002 |
Sarcopenia--consequences, mechanisms, and potential therapies.
Topics: Aged; Aging; Dehydroepiandrosterone; Exercise Therapy; Female; Hormone Replacement Therapy; Human Gr | 2003 |
Cognitive functions and sex steroids.
Topics: Aged; Aging; Animals; Cognition; Dehydroepiandrosterone; Estradiol; Female; Gonadal Steroid Hormones | 2003 |
[Hormones against aging? A critical analysis of scientific data].
Topics: Aging; Dehydroepiandrosterone; Endocrine System; Estrogens; Hormone Replacement Therapy; Hormones; H | 2003 |
Dehydroepiandrosterone - is the fountain of youth drying out?
Topics: Aged; Aging; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; Humans; Male | 2003 |
Prevention of diabetes, hepatic injury, and colon cancer with dehydroepiandrosterone.
Topics: Aging; Animals; Colonic Neoplasms; Dehydroepiandrosterone; Diabetes Mellitus; Gluconeogenesis; Human | 2003 |
Androgen therapy with dehydroepiandrosterone.
Topics: Adjuvants, Immunologic; Adrenal Insufficiency; Aged; Aging; Cardiovascular Diseases; Cognition; Dehy | 2003 |
[Clinical significance of dehydroepiandrosterone (DHEA) supplement therapy].
Topics: Aged; Aging; Animals; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Rats | 2003 |
Pharmacology and therapeutic effects of dehydroepiandrosterone in older subjects.
Topics: Age Factors; Aged; Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; H | 2003 |
Interacting mediators of allostasis and allostatic load: towards an understanding of resilience in aging.
Topics: Aging; Brain; Catecholamines; Cytokines; Dehydroepiandrosterone; Glucocorticoids; Humans | 2003 |
[DHEA: hormone as antiaging remedies].
Topics: Aged; Aging; Animals; Anti-Inflammatory Agents; Brain; Dehydroepiandrosterone; Dementia; Female; Hum | 2003 |
Therapeutic uses of dehydroepiandrosterone.
Topics: Adrenal Insufficiency; Aging; Animals; Bone Density; Chronic Disease; Dehydroepiandrosterone; Humans | 2003 |
Dehydroepiandrosterone and ageing.
Topics: Adrenal Insufficiency; Aged; Aging; Animals; Body Composition; Bone and Bones; Central Nervous Syste | 2004 |
Pitfalls of animal model systems in ageing research.
Topics: Aging; Animals; Biomarkers; Dehydroepiandrosterone; Humans; Models, Animal; Research; Resveratrol; S | 2004 |
Stress responses and innate immunity: aging as a contributory factor.
Topics: Adrenal Cortex; Adrenal Medulla; Aged; Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosteron | 2004 |
Hormones and immune function: implications of aging.
Topics: Aging; Calcitriol; Dehydroepiandrosterone; Hormones; Human Growth Hormone; Humans; Immunity; Melaton | 2004 |
[Hormone therapy in the aging male. Estrogen, DHEA, melatonin, somatotropin].
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Estrogens; Growth Hormone; Hormone Replaceme | 2004 |
[Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulphate (DHEAS) in men with coronary artery disease].
Topics: Age Factors; Aging; Animals; Coronary Artery Disease; Dehydroepiandrosterone; Dehydroepiandrosterone | 2004 |
Adrenopause.
Topics: Adrenal Glands; Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Endocrine Sy | 2004 |
Adrenal androgens and intracrinology.
Topics: Adrenal Glands; Aging; Androgens; Dehydroepiandrosterone; Female; Humans; Male; Postmenopause | 2004 |
Adrenal androgens and aging.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aging; Androgens; Animals; Dehydroepiandrosterone; Dehy | 2004 |
Dehydroepiandrosterone replacement therapy.
Topics: Adrenal Insufficiency; Aging; Animals; Autoimmune Diseases; Cognition Disorders; Dehydroepiandroster | 2004 |
[DHEA and aging].
Topics: Adjuvants, Immunologic; Aged; Aging; Alzheimer Disease; Cognition Disorders; Dehydroepiandrosterone; | 2003 |
Overview of resistance training, diet, hormone replacement and nutritional supplements on age-related sarcopenia--a minireview.
Topics: Adult; Aged; Aging; Amino Acids, Branched-Chain; Dehydroepiandrosterone; Dietary Proteins; Exercise; | 2003 |
[Is there a place for DHEA, GH and melatonin in the management of age-related androgen deficiency?].
Topics: Age Factors; Aged; Aging; Androgens; Clinical Trials as Topic; Dehydroepiandrosterone; Growth Hormon | 2004 |
The use of dehydroepiandrosterone therapy in clinical practice.
Topics: Adrenal Insufficiency; Aging; Alzheimer Disease; Bone Density; Cardiovascular Diseases; Dehydroepian | 2005 |
[Focus on dehydroepiandrosterone (DHEA)].
Topics: Adrenal Insufficiency; Aging; Body Composition; Dehydroepiandrosterone; Humans; Lupus Erythematosus, | 2005 |
The decline of androgen levels in elderly men and its clinical and therapeutic implications.
Topics: Aged; Aging; Androgens; Atherosclerosis; Clinical Trials as Topic; Coronary Disease; Dehydroepiandro | 2005 |
Dehydroepiandrosterone, dehydroepiandrosterone sulfate and related steroids: their role in inflammatory, allergic and immunological disorders.
Topics: Aging; Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Cytokines; Dehydroepiandrosterone; De | 2005 |
Androgens, insulin resistance and vascular disease in men.
Topics: Aged; Aging; Arteriosclerosis; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Humans; Insulin Re | 2005 |
Sarcopenia of aging and its metabolic impact.
Topics: Aging; Animals; Dehydroepiandrosterone; Estrogens; Exercise; Female; Human Growth Hormone; Humans; M | 2005 |
Dehydroepiandrosterone treatment in the aging male--what should the urologist know?
Topics: Aging; Cardiovascular Physiological Phenomena; Clinical Trials as Topic; Dehydroepiandrosterone; Die | 2005 |
The trajectory of biomarkers in symptom management for older adults with cancer.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aged; Aging; Anxiety; Biomarkers; Biomarkers, Tumor; Cy | 2006 |
[Dehydroepiandrosterone (DHEA)--slows down the aging process?].
Topics: Aging; Dehydroepiandrosterone; Humans | 2005 |
Dehydroepiandrosterone therapy as female androgen replacement.
Topics: Adrenal Insufficiency; Aging; Androgens; Dehydroepiandrosterone; Female; Hormone Replacement Therapy | 2006 |
Stress and dementia: the role of the hypothalamicpituitary-adrenal axis.
Topics: Adult; Aged; Aging; Alzheimer Disease; Case-Control Studies; Circadian Rhythm; Cognition Disorders; | 2006 |
The native anti-glucocorticoid paradigm.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aging; Animals; Brain; Cortisone; Cytochrome P-450 Enzy | 2006 |
The hormonal fountains of youth: myth or reality?
Topics: Aging; Animals; Dehydroepiandrosterone; Estrogens; Female; Growth Hormone; Hormone Replacement Thera | 2005 |
Sexuality in aging male.
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Erectile Dysfunction; Fertility; Growth Horm | 2005 |
Male aging and hormones: the adrenal cortex.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Aging; Andropause; Dehy | 2005 |
Controversial endocrine interventions for the aged.
Topics: Aged; Aging; Dehydroepiandrosterone; Endocrine System; Growth Hormone; Growth Hormone-Releasing Horm | 2006 |
Dietary restriction in aging nonhuman primates.
Topics: Aging; Animals; Basal Metabolism; Caloric Restriction; Dehydroepiandrosterone; Hydrocortisone; Insul | 2007 |
Female androgen insufficiency.
Topics: Adrenal Glands; Aging; Algorithms; Androgens; Dehydroepiandrosterone; Female; Humans; Libido; Ovarie | 2006 |
Hope drives antiaging hype.
Topics: Aging; Antioxidants; Dehydroepiandrosterone; Dietary Supplements; Growth Hormone; Hormones; Humans; | 2006 |
Antioxidants and hormones as antiaging therapies: high hopes, disappointing results.
Topics: Aging; Antioxidants; Cardiovascular Diseases; Cerebrovascular Disorders; Cognition; Dehydroepiandros | 2006 |
Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging.
Topics: Aging; Animals; Apoptosis; Dehydroepiandrosterone; Humans; Neuroimmunomodulation; Neurons; Pregnanol | 2006 |
The endocrine system and ageing.
Topics: Aging; Androgens; Dehydroepiandrosterone; Endocrine System; Female; Gonadotropins, Pituitary; Hormon | 2007 |
Androgens and the brain.
Topics: Aging; Androgens; Animals; Brain; Dehydroepiandrosterone; Female; Haplorhini; Hormone Replacement Th | 2007 |
[Hormone replacement Up-to-date. Adrenopause and DHEA replacement therapy].
Topics: Aging; Animals; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; Humans; Male | 2007 |
Androgens in the etiology of Alzheimer's disease in aging men and possible therapeutic interventions.
Topics: Aged; Aging; Alzheimer Disease; Androgens; Cognition Disorders; Dehydroepiandrosterone; Follicle Sti | 2007 |
Potential biomarkers of ageing.
Topics: Aging; Animals; Biomarkers; Cellular Senescence; Dehydroepiandrosterone; Estrogens; Growth Hormone; | 2008 |
Dehydroepiandrosterone in adrenal insufficiency and ageing.
Topics: Adrenal Insufficiency; Aging; Antigens, CD; Bone Density; Dehydroepiandrosterone; Humans; Lipid Meta | 2008 |
[Replacement and supplementation of DHEA--is it a wellness hormone?].
Topics: Addison Disease; Adjuvants, Immunologic; Administration, Oral; Adult; Age Factors; Aged; Aged, 80 an | 2005 |
Control of adrenal androgen secretion.
Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Androge | 1980 |
Steroid hormones, ageing and bone.
Topics: Adult; Aged; Aging; Androstenedione; Bone and Bones; Calcium; Castration; Dehydroepiandrosterone; Es | 1981 |
Biosynthesis and assay of neurosteroids in rats and mice: functional correlates.
Topics: Adrenalectomy; Aggression; Aging; Animals; Behavior, Animal; Dehydroepiandrosterone; Dihydrotestoste | 1995 |
Studies on dehydroepiandrosterone (DHEA) and its sulphate during aging.
Topics: Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male | 1995 |
[Aged people and stress].
Topics: Aged; Aging; Biomarkers; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Male; Stress, Physi | 1994 |
Role of adrenocortical steroids in mediating cancer-preventive and age-retarding effects of food restriction in laboratory rodents.
Topics: Aging; Animals; Dehydroepiandrosterone; Food Deprivation; Glucocorticoids; Mice; Neoplasms, Experime | 1994 |
Immune senescence and adrenal steroids: immune dysregulation and the action of dehydroepiandrosterone (DHEA) in old animals.
Topics: Aging; Animals; Antibody Formation; Autoantibodies; B-Lymphocyte Subsets; Cytokines; Dehydroepiandro | 1993 |
Dehydroepiandrosterone sulfate and aging.
Topics: Adrenal Cortex; Adult; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosteron | 1995 |
Neuronal actions of dehydroepiandrosterone. Possible roles in brain development, aging, memory, and affect.
Topics: Aggression; Aging; Animals; Brain; Circadian Rhythm; Cognition; Dehydroepiandrosterone; Dehydroepian | 1995 |
Does DHEAS restore immune competence in aged animals through its capacity to function as a natural modulator of peroxisome activities?
Topics: Aging; Animals; Cytokines; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Immunity; Mice; M | 1995 |
Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline.
Topics: Adrenal Cortex; Aging; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chromatogra | 1995 |
[Dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S)].
Topics: Adult; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Femal | 1995 |
Dehydroepiandrosterone (DHEA): a fountain of youth?
Topics: Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male | 1996 |
Dehydroepiandrosterone and diseases of aging.
Topics: Aged; Aging; Animals; Dehydroepiandrosterone; Geriatrics; Humans; Mice | 1996 |
[Actions of dehydroepiandrosterone: possible links with aging].
Topics: Aging; Animals; Dehydroepiandrosterone; Female; Humans; Male | 1996 |
The use of anti-aging hormones. Melatonin, growth hormone, testosterone, and dehydroepiandrosterone: consumer enthusiasm for unproven therapies.
Topics: Aging; Animals; Dehydroepiandrosterone; Female; Human Growth Hormone; Humans; Male; Melatonin; Nonpr | 1997 |
The endocrinology of aging.
Topics: Adrenal Glands; Aged; Aged, 80 and over; Aging; Animals; Climacteric; Dehydroepiandrosterone; Endocr | 1997 |
Neurosteroids: a role in aging? New functions in the central and peripheral nervous systems.
Topics: Aging; Animals; Central Nervous System; Dehydroepiandrosterone; Peripheral Nervous System; Pregnenol | 1997 |
DHEA replacement therapy for human aging: a call for perspective.
Topics: Aging; Dehydroepiandrosterone; Humans | 1997 |
DHEA: a biologist's perspective.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aging; Androgens; Animals; Breast Neoplasms; Dehydroepiandr | 1997 |
Ageing and adrenal cortical function.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adult; Aged; Aging; Animals; Dehydroepiandrosterone; Energy | 1997 |
Any facts behind the DHEA hype?
Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa | 1997 |
[Dehydroepiandrosterone, "the youth hormone", in the light of recent findings].
Topics: Aging; Dehydroepiandrosterone; Humans | 1998 |
[Prasterone (dihydroepiandrosterone): a modern source of eternal youth?].
Topics: Aging; Androgens; Animals; Clinical Trials as Topic; Dehydroepiandrosterone; Humans; Nonprescription | 1997 |
Wishing a dream came true: DHEA as a rejuvenating treatment?
Topics: Affect; Aging; Cognition; Dehydroepiandrosterone; Electroencephalography; Female; Humans; Male | 1998 |
DHEA: science or wishful thinking?
Topics: Adult; Aged; Aging; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Obesity; Osteoporosis | 1998 |
[Selected endocrinological problems in mature and elderly men].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Estrogens; Female; Human | 1998 |
Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DS) as therapeutic options in menopause.
Topics: Adult; Aging; Animals; Bone Remodeling; Cardiovascular System; Dehydroepiandrosterone; Estrogen Repl | 1998 |
Hormone replacement for disabilities and diseases of aging.
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Aging; Child; Dehydroepiandrosterone; Dehydr | 1998 |
Review: Ageing and hormones.
Topics: Aging; Dehydroepiandrosterone; Estrogens; Hormone Replacement Therapy; Hormones; Human Growth Hormon | 1999 |
Is there a case for DHEA replacement?
Topics: Adult; Aged; Aging; Alzheimer Disease; Animals; Arteriosclerosis; Bone Remodeling; Carbohydrate Meta | 1998 |
[On the healthy male aging: hormonal aspects].
Topics: Aged; Aging; Climacteric; Dehydroepiandrosterone; Health Status; Human Growth Hormone; Humans; Hypog | 1999 |
Calorie restriction in primates: will it work and how will we know?
Topics: Aging; Analysis of Variance; Animals; Biomarkers; Body Weight; Cardiovascular Diseases; Cause of Dea | 1999 |
DHEA: panacea or snake oil?
Topics: Adjuvants, Immunologic; Aging; Dehydroepiandrosterone; Female; Heart Diseases; Humans; Immune System | 1999 |
DHEA deficiency syndrome: a new term for old age?
Topics: Adolescent; Adrenal Cortex; Adult; Aged; Aged, 80 and over; Aging; Child; Cognition Disorders; Dehyd | 1999 |
Dehydroepiandrosterone and dehydroepiandrosterone sulfate production in the human adrenal during development and aging.
Topics: Adrenal Glands; Adult; Aging; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; | 1999 |
[Are the hormones of youth carcinogenic?].
Topics: Aging; Dehydroepiandrosterone; Estrogens; Female; Hormones; Human Growth Hormone; Humans; Insulin-Li | 1999 |
Approaches to anti-aging intervention: the promises and the uncertainties.
Topics: Aging; Antioxidants; Dehydroepiandrosterone; Diet; Estrogens; Geriatrics; Growth Hormone; Humans; Li | 1999 |
DHEA and the skeleton (through the ages).
Topics: Adult; Aging; Animals; Bone and Bones; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Human | 1999 |
Hormone replacement in the aging male?.
Topics: Aging; Androgens; Dehydroepiandrosterone; Hormone Replacement Therapy; Human Growth Hormone; Humans; | 1999 |
[Is aging associated with a diminution of insulin sensitivity? Roles of IGF1 and dehydroepiandrosterone].
Topics: Aged; Aging; Body Composition; Body Mass Index; Dehydroepiandrosterone; Diet; Exercise; Humans; Insu | 1999 |
The effects of dehydroepiandrosterone on carcinogenesis, obesity, the immune system, and aging.
Topics: Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Glucosephosphate Dehydrogena | 2000 |
Changes in adrenocortical function with aging and therapeutic implications.
Topics: Adjuvants, Immunologic; Adrenal Gland Diseases; Aged; Aging; Androgens; Dehydroepiandrosterone; Fema | 1999 |
[Endocrine and metabolic functional disorders in extreme old age].
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Clinical Trials as Topic; Dehydroepiandrosterone; Diabe | 2000 |
The biology of aging.
Topics: Aged; Aging; Animals; Dehydroepiandrosterone; Diet, Fat-Restricted; Energy Intake; Exercise; Female; | 2000 |
Age-related changes in muscle.
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Energy Metabolism; Exercise; Hormone Replace | 2000 |
Endocrinological aspects of aging in men: is hormone replacement of benefit?
Topics: Aging; Body Composition; Bone and Bones; Bone Density; Dehydroepiandrosterone; Endocrine Glands; Hor | 2000 |
The male climacterium: clinical signs and symptoms of a changing endocrine environment.
Topics: Aging; Climacteric; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Endocrine Glands; Humans | 2000 |
[Replacement therapy in adrenopause. Dehydroepiandrosterone and aging].
Topics: Aging; Blood Glucose; Bone and Bones; Bone Density; Cardiovascular Physiological Phenomena; Central | 2001 |
Intraadrenal mechanisms of DHEA regulation: a hypothesis for adrenopause.
Topics: Adrenal Glands; Aging; Androgens; Dehydroepiandrosterone; Humans; Models, Biological | 2001 |
Dehydroepiandrosterone replacement for patients with adrenal insufficiency.
Topics: Addison Disease; Adjuvants, Immunologic; Adult; Aged; Aging; Dehydroepiandrosterone; Female; Humans; | 2001 |
[Neuropsychic effects of dehydroepiandrosterone].
Topics: Affect; Aging; Animals; Attention; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandros | 2001 |
Dehydroepiandrosterone replacement therapy.
Topics: Adult; Aged; Aging; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; Humans; Male; Middl | 2001 |
DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology.
Topics: Adult; Aged; Aging; Androgens; Dehydroepiandrosterone; Enzymes; Estrogens; Female; Humans; Male; Mid | 2001 |
Clinical implications of circulating neurosteroids.
Topics: Aging; Alzheimer Disease; Dehydroepiandrosterone; Female; Humans; Male; Menopause; Menstrual Cycle; | 2001 |
[DHEA: orthodox or alternative medicine?].
Topics: Adjuvants, Immunologic; Adrenal Insufficiency; Aged; Aging; Complementary Therapies; Dehydroepiandro | 2001 |
Dehydroepiandrosterone and the relationship with aging and memory: a possible link with protein kinase C functional machinery.
Topics: Aging; Animals; Dehydroepiandrosterone; Enzyme Activation; Humans; Memory; Memory Disorders; Protein | 2001 |
Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging.
Topics: Aging; Animals; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hippocampus; Huma | 2001 |
[Testosterone and dehydroepiandrosterone deficiency, general adiposity and visceral obesity during normal male aging].
Topics: Adipose Tissue; Aging; Body Mass Index; Dehydroepiandrosterone; Humans; Male; Middle Aged; Obesity; | 2001 |
DHEA(S): the fountain of youth.
Topics: Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Inflammation | 2001 |
[Dehydroepiandrosterone (DHEA)--youth hormone?].
Topics: Aging; Arteriosclerosis; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes | 2001 |
Uses of DHEA in aging and other disease states.
Topics: Aging; Dehydroepiandrosterone; Dietary Supplements; Female; Humans; Male | 2002 |
Mechanism of action of anti-aging DHEA-S and the replacement of DHEA-S.
Topics: Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hormone Replacement Therapy; Humans | 2002 |
Prolactin and human breast cancer: a review.
Topics: Adolescent; Adult; Aging; Breast Neoplasms; Child; Child, Preschool; Circadian Rhythm; Contraceptive | 1979 |
Dehydroepiandrosterone: the "missing link" between hyperinsulinemia and atherosclerosis?
Topics: Aging; Animals; Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hy | 1992 |
Dehydroepiandrosterone and dehydroepiandrosterone sulfate: their relation to cardiovascular disease.
Topics: Adolescent; Adult; Aged; Aging; Animals; Arteriosclerosis; Biomarkers; Cardiovascular Diseases; Case | 1991 |
Hormonal intervention: "buffer hormones" or "state dependency". The role of dehydroepiandrosterone (DHEA), thyroid hormone, estrogen and hypophysectomy in aging.
Topics: Aging; Animals; Cell Transformation, Neoplastic; Dehydroepiandrosterone; Diabetes Mellitus; Estrogen | 1988 |
Control of secretion and the function of C19-delta 5-steroids of the human adrenal gland.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; | 1985 |
Life extension.
Topics: Aged; Aging; Animals; Antioxidants; Dehydroepiandrosterone; Diet; Energy Intake; Ethics, Medical; Fe | 1985 |
[The adrenal cortex].
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aging; Aldosterone; Binding, Competitive; Child; Chromatogr | 1973 |
[Aging and the adrenal cortex].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; | 1969 |
42 trials available for dehydroepiandrosterone and Aging
| Article | Year |
|---|---|
The effect of pilates training on hormonal and psychophysical function in older women.
Topics: Aged; Aging; Anxiety; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Exercise Movement Tech | 2022 |
Dehydroepiandrosterone Shifts Energy Metabolism to Increase Mitochondrial Biogenesis in Female Fertility with Advancing Age.
Topics: Adult; Aging; Cellular Senescence; Cumulus Cells; Dehydroepiandrosterone; Dietary Supplements; Energ | 2021 |
Efficacy of Dehydroepiandrosterone (DHEA) to overcome the effect of ovarian ageing (DITTO): A proof of principle double blinded randomized placebo controlled trial.
Topics: Adult; Aging; Androgens; Dehydroepiandrosterone; Double-Blind Method; Female; Fertilization in Vitro | 2017 |
Resistance training restores muscle sex steroid hormone steroidogenesis in older men.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Adult; Aged; Aging; Cholestenone | 2014 |
Low Serum DHEAS Predicts Increased Fracture Risk in Older Men: The MrOS Sweden Study.
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Fractures, Bone; Humans; Incidence; Male; Os | 2017 |
Neuroendocrine effects of citalopram, a selective serotonin re-uptake inhibitor, during lifespan in humans.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Citalopram; Dehydroepiandrosterone; Humans; Hydroco | 2010 |
Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans.
Topics: Aged; Aging; Animals; Blood Chemical Analysis; Cytokines; Dehydroepiandrosterone; Energy Intake; Exe | 2011 |
Basal growth hormone concentration increased following a weight loss focused dietary intervention in older overweight and obese women.
Topics: Aged; Aging; Dehydroepiandrosterone; Female; Human Growth Hormone; Humans; Hydrocortisone; Male; Nut | 2012 |
Effect of 1-year oral administration of dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: a double-blind placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Double-Blind | 2003 |
Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency.
Topics: Aged; Aging; Androgens; Andropause; Arthralgia; beta-Endorphin; Dehydroepiandrosterone; Dehydroepian | 2004 |
Hypothalamus-pituitary-adrenal hyperactivity in human aging is partially refractory to stimulation by mineralocorticoid receptor blockade.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Canrenoic Acid; Circadian Rhythm; Dehydroepiandrost | 2005 |
The effect of vitamin E supplementation on serum DHEA and neopterin levels in elderly subjects.
Topics: Aged; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dietary Supplements; Female; Hu | 2005 |
Beneficial effects and side effects of DHEA: true anti-aging and age-promoting effects, as well as anti-cancer and cancer-promoting effects of DHEA evaluated from the effects on the normal and cancer cell telomeres and other parameters.
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Aging; Antineoplastic Agents; Chromosome Abe | 2005 |
Effects of dehydroepiandrosterone replacement therapy on bone mineral density in older adults: a randomized, controlled trial.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Bone Density; Calcium, Dietary; Dehydroepiandroste | 2006 |
The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methods.
Topics: Adjuvants, Immunologic; Aged; Aged, 80 and over; Aging; Body Composition; Bone Density; California; | 2007 |
DHEA enhances effects of weight training on muscle mass and strength in elderly women and men.
Topics: Adjuvants, Immunologic; Aged; Aging; Dehydroepiandrosterone; Exercise; Female; Humans; Insulin-Like | 2006 |
Dehydroepiandrosterone secretion in healthy older men and women: effects of testosterone and growth hormone administration in older men.
Topics: Aged; Aged, 80 and over; Aging; Body Mass Index; Circadian Rhythm; Dehydroepiandrosterone; Dehydroep | 2006 |
DHEA in elderly women and DHEA or testosterone in elderly men.
Topics: Adult; Aged; Aging; Body Composition; Bone Density; Dehydroepiandrosterone; Double-Blind Method; Est | 2006 |
Changes in serum sex hormone profiles after short-term low-dose administration of dehydroepiandrosterone (DHEA) to young and elderly persons.
Topics: Adult; Aging; Cell Adhesion Molecules; Cytokines; Dehydroepiandrosterone; Dose-Response Relationship | 2007 |
Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.
Topics: Adult; Aged; Aging; Apolipoprotein A-I; Apolipoproteins B; Blood Glucose; Carrier Proteins; Choleste | 1994 |
Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.
Topics: Adult; Aged; Aging; Apolipoprotein A-I; Apolipoproteins B; Blood Glucose; Carrier Proteins; Choleste | 1994 |
Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.
Topics: Adult; Aged; Aging; Apolipoprotein A-I; Apolipoproteins B; Blood Glucose; Carrier Proteins; Choleste | 1994 |
Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.
Topics: Adult; Aged; Aging; Apolipoprotein A-I; Apolipoproteins B; Blood Glucose; Carrier Proteins; Choleste | 1994 |
Correlation between plasma lipoprotein Lp(a) and sex hormone concentrations: a cross-sectional study in healthy males.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cholesterol, LDL; Dehydroepiandrosterone; Gonadal Steroid Hor | 1994 |
Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men.
Topics: Aged; Aging; Androgens; Blood Glucose; Blood Pressure; Dehydroepiandrosterone; Dehydroepiandrosteron | 1995 |
Age and sex differences of dehydroepiandrosterone sulfate (DHEAS) and cortisol (CRT) plasma levels in normal controls and Alzheimer's disease (AD).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Atrophy; Cerebral Cortex; Dehy | 1993 |
The relation of smoking, age, relative weight, and dietary intake to serum adrenal steroids, sex hormones, and sex hormone-binding globulin in middle-aged men.
Topics: Adrenal Glands; Adult; Aged; Aging; Body Mass Index; Body Weight; Cross-Sectional Studies; Dehydroep | 1994 |
Replacement of DHEA in aging men and women. Potential remedial effects.
Topics: Administration, Oral; Adult; Aged; Aging; Body Composition; Cross-Over Studies; Dehydroepiandrostero | 1995 |
DHEAS as an effective vaccine adjuvant in elderly humans. Proof-of-principle studies.
Topics: Adjuvants, Immunologic; Aged; Aging; Animals; Antibodies, Viral; Dehydroepiandrosterone; Dehydroepia | 1995 |
Activation of immune function by dehydroepiandrosterone (DHEA) in age-advanced men.
Topics: Aged; Aging; Dehydroepiandrosterone; Hormones; Humans; Immune System; Lymphocyte Subsets; Male; Midd | 1997 |
Dehydroepiandrosterone treatment is not beneficial to the immune response to influenza in elderly subjects.
Topics: Aged; Aged, 80 and over; Aging; Antibody Formation; Dehydroepiandrosterone; Dehydroepiandrosterone S | 1997 |
The influence of sequential annual vaccination and of DHEA administration on the efficacy of the immune response to influenza vaccine in the elderly.
Topics: Adjuvants, Immunologic; Aged; Aging; Dehydroepiandrosterone; Double-Blind Method; Female; Follow-Up | 1998 |
The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women.
Topics: Aged; Aging; Androstenedione; Body Composition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa | 1998 |
Dehydroepiandrosterone replacement in aging humans.
Topics: Activities of Daily Living; Aged; Aging; Body Composition; Cross-Over Studies; Dehydroepiandrosteron | 1999 |
Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig cell) defects in the healthy aging male gonadotropic axis.
Topics: Adult; Aged; Aging; Cross-Over Studies; Dehydroepiandrosterone; Double-Blind Method; Follicle Stimul | 1999 |
Effects of aging on adrenal function in the human: responsiveness and sensitivity of adrenal androgens and cortisol to adrenocorticotropin in premenopausal and postmenopausal women.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Androgens; Androstenedione; Body Ma | 2000 |
Acute oral administration of dehydroepiandrosterone in male subjects: effect of age on bioavailability, sulfoconjugation and bioconversion in other steroids.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Biological Availability; Dehydroepiandr | 1999 |
Serum profile of dehydroepiandrosterone (DHEA) concentrations in DHEA-supplemented elderly subjects.
Topics: Adult; Aged; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dietary Supplements; Female; Humans; H | 1999 |
Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue.
Topics: Absorptiometry, Photon; Aged; Aging; Blood Vessels; Bone Remodeling; Dehydroepiandrosterone; Dehydro | 2000 |
Sexual dimorphism in the influence of advanced aging on adrenal hormone levels: the Rancho Bernardo Study.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Aging; Body Composition; Cross-Sectional Studies; | 2000 |
Altered salivary dehydroepiandrosterone levels in major depression in adults.
Topics: Adult; Aging; Antidepressive Agents; Circadian Rhythm; Dehydroepiandrosterone; Depressive Disorder; | 2000 |
Effect of estrogen on serum DHEA in younger and older women and the relationship of DHEA to adiposity and gender.
Topics: Adipose Tissue; Adolescent; Adult; Aging; Body Mass Index; Case-Control Studies; Contraceptives, Ora | 2001 |
Salivary cortisol and DHEA: association with measures of cognition and well-being in normal older men, and effects of three months of DHEA supplementation.
Topics: Affect; Aged; Aging; Anxiety; Circadian Rhythm; Cognition; Cross-Over Studies; Dehydroepiandrosteron | 2001 |
Dehydroepiandrosterone supplementation and bone turnover in middle-aged to elderly men.
Topics: Aged; Aged, 80 and over; Aging; Bone Remodeling; Cross-Over Studies; Dehydroepiandrosterone; Dose-Re | 2002 |
The effects of oral dehydroepiandrosterone on endocrine-metabolic parameters in postmenopausal women.
Topics: Administration, Oral; Adrenal Glands; Aged; Aging; Androgens; Body Weight; Dehydroepiandrosterone; D | 1990 |
329 other studies available for dehydroepiandrosterone and Aging
| Article | Year |
|---|---|
Age-related decrease in serum dihydrotestosterone concentration is accompanied by impaired vascular status.
Topics: Adult; Aged; Aging; Androgens; Androstenedione; Carotid Arteries; Carotid Intima-Media Thickness; De | 2023 |
Intrinsic capacity differs from functional ability in predicting 10-year mortality and biological features in healthy aging: results from the I-Lan longitudinal aging study.
Topics: Aging; Dehydroepiandrosterone; Healthy Aging; Humans; Longitudinal Studies; Vitamin D Deficiency | 2023 |
Developmental Programming-Aging Interactions Have Sex-Specific and Developmental Stage of Exposure Outcomes on Life Course Circulating Corticosterone and Dehydroepiandrosterone (DHEA) Concentrations in Rats Exposed to Maternal Protein-Restricted Diets.
Topics: Aging; Animals; Corticosterone; Dehydroepiandrosterone; Diet, Protein-Restricted; Female; Male; Preg | 2023 |
Hormone Therapy: Aging-Related Hormone Replacement Therapy and Supplementation.
Topics: Aging; Dehydroepiandrosterone; Dietary Supplements; Hormone Replacement Therapy; Humans; Melatonin | 2023 |
Testosterone and Estrone Increase From the Age of 70 Years: Findings From the Sex Hormones in Older Women Study.
Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Community-Based Participatory Research; Cross-Sectional | 2019 |
Dehydroepiandrosterone supplementation attenuates ovarian ageing in a galactose-induced primary ovarian insufficiency rat model.
Topics: Aging; Animals; Dehydroepiandrosterone; Dietary Supplements; Disease Models, Animal; Female; Galacto | 2019 |
Lack of effect of short-term DHEA supplementation on the perimenopausal ovary†.
Topics: Aging; Animals; Dehydroepiandrosterone; Drug Administration Schedule; Female; Macaca mulatta; Ovary; | 2020 |
Androgens and Heart Failure: New Observations Illuminating an Aging Conundrum.
Topics: Aging; Androgens; Androstenedione; Dehydroepiandrosterone; Heart Failure; Humans | 2021 |
Consumption of green tea epigallocatechin-3-gallate enhances systemic immune response, antioxidative capacity and HPA axis functions in aged male swiss albino mice.
Topics: Aging; Animals; Antibody Formation; Antioxidants; Catechin; Dehydroepiandrosterone; Dose-Response Re | 2017 |
Effect of androgen supplementation on 24-hour activity-rest patterns of aged male rhesus macaques.
Topics: Aging; Animals; Dehydroepiandrosterone; Dietary Supplements; Macaca mulatta; Male; Physical Conditio | 2017 |
The effect of DHEA on apoptosis and cohesin levels in oocytes in aged mice.
Topics: Aging; Animals; Anti-Mullerian Hormone; Apoptosis; Cell Cycle Proteins; Chromosomal Proteins, Non-Hi | 2017 |
Dehydroepiandrosterone as a potential agent to slow down ovarian aging.
Topics: Adult; Aging; Cell Line; Cellular Senescence; Cohort Studies; Cumulus Cells; Dehydroepiandrosterone; | 2017 |
Incarnation and the dynamics of medical promises: DHEA as a fountain of youth hormone.
Topics: Adjuvants, Immunologic; Aging; Dehydroepiandrosterone; Evidence-Based Medicine; Hormone Replacement | 2019 |
DHEA Treatment Effects on Redox Environment in Skeletal Muscle of Young and Aged Healthy Rats.
Topics: Age Factors; Aging; Animals; Biomarkers; Dehydroepiandrosterone; Enzyme Activation; Glucosephosphate | 2018 |
Involvement of serum dehydroepiandrosterone sulfate in erythropoietic activity.
Topics: Aged; Aging; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male | 2020 |
Modulation of higher-primate adrenal androgen secretion with estrogen-alone or estrogen-plus-progesterone intervention.
Topics: Adrenal Glands; Aging; Androgens; Androstenediol; Animals; Dehydroepiandrosterone; Dehydroepiandrost | 2013 |
DHEA--finding a role for this enigmatic hormone.
Topics: Adult; Aging; Dehydroepiandrosterone; Dietary Supplements; Female; Humans; Pregnancy; Primary Ovaria | 2013 |
Interactive effects of dehydroepiandrosterone and testosterone on cortical thickness during early brain development.
Topics: Adolescent; Aging; Brain; Cerebral Cortex; Child; Child, Preschool; Dehydroepiandrosterone; Female; | 2013 |
Physical activity, life events stress, cortisol, and DHEA: preliminary findings that physical activity may buffer against the negative effects of stress.
Topics: Aged; Aging; Circadian Rhythm; Dehydroepiandrosterone; Exercise; Female; Humans; Hydrocortisone; Lif | 2014 |
The role of hormones and aromatase inhibitors on breast tumor growth and general health in a postmenopausal mouse model.
Topics: Aging; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone; Disease M | 2014 |
[Hormonal deficiencies in the elderly: is there a role for replacement therapy?].
Topics: Adjuvants, Immunologic; Aged; Aging; Androgens; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; F | 2014 |
Improvement of neuronal bioenergetics by neurosteroids: implications for age-related neurodegenerative disorders.
Topics: Adenosine Triphosphate; Aging; Androstane-3,17-diol; Animals; Cell Line, Tumor; Cell Proliferation; | 2014 |
The utility and dynamics of salivary sex hormone measurements in the National Social Life, Health, and Aging Project, Wave 2.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Estradiol; Female; Gonadal Ster | 2014 |
[Immune dysfunction and cognitive deficit in stress and physiological aging. Part II: New approaches to cognitive disorder prevention and treatment ].
Topics: Adaptation, Physiological; Adaptation, Psychological; Adjuvants, Immunologic; Aging; Angiotensin II | 2014 |
DHEA replacement for postmenopausal women: placebo or panacea?
Topics: Administration, Intravaginal; Administration, Oral; Aged; Aging; Cognition Disorders; Dehydroepiandr | 2015 |
Mathematical modelling of decline in follicle pool during female reproductive ageing.
Topics: Adult; Aging; Anti-Mullerian Hormone; Dehydroepiandrosterone; Female; Humans; Middle Aged; Models, T | 2016 |
Hormonal determinants of the severity of andropausal and depressive symptoms in middle-aged and elderly men with prediabetes.
Topics: Aged; Aged, 80 and over; Aging; Andropause; Dehydroepiandrosterone; Depression; Humans; Insulin-Like | 2015 |
Effect of dehydroepiandrosterone treatment on hormone levels and antioxidant parameters in aged rats.
Topics: Aging; Aldosterone; Animals; Antioxidants; Body Weight; Dehydroepiandrosterone; Drug Evaluation, Pre | 2015 |
Effect of age, gender and exercise on salivary dehydroepiandrosterone circadian rhythm profile in human volunteers.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Exercise; Female; Healthy Volunteers; Humans | 2016 |
Precipitous Dehydroepiandrosterone Declines Reflect Decreased Physical Vitality and Function.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Chronic Disease; Chronic Pain; Dehydroepiandroste | 2017 |
The rate of change in declining steroid hormones: a new parameter of healthy aging in men?
Topics: Adult; Aged; Aging; Biomarkers; Dehydroepiandrosterone; Depression; Estradiol; Gonadal Steroid Hormo | 2016 |
Dehydroepiandrosterone increases the number and dendrite maturation of doublecortin cells in the dentate gyrus of middle age male Wistar rats exposed to chronic mild stress.
Topics: Aging; Animals; Antigens, Nuclear; Body Weight; Bromodeoxyuridine; Cell Survival; Chronic Disease; D | 2017 |
Potential prevention by oral DHEA of superficial tears in elderly atrophic skin.
Topics: Aged; Aged, 80 and over; Aging; Atrophy; Clinical Trials as Topic; Dehydration; Dehydroepiandrostero | 2017 |
Adiponectin is involved in the protective effect of DHEA against metabolic risk in aged rats.
Topics: Adiponectin; Adipose Tissue; Aging; Animals; Blood Glucose; Body Weight; Cholesterol; Dehydroepiandr | 2008 |
Genistein-induced histomorphometric and hormone secreting changes in the adrenal cortex in middle-aged rats.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aging; Aldosterone; Animals; Body Weight; Corticosterone; D | 2009 |
Treatment with dehydroepiandrosterone increases peripheral benzodiazepine receptors of mitochondria from cerebral cortex in D-galactose-induced aged rats.
Topics: Aging; Animals; Cerebral Cortex; Cognition; Dehydroepiandrosterone; Female; Galactose; Male; Maze Le | 2008 |
Na+ K(+)-ATPase activity in response to exogenous dehydroepiandrosterone administration in aging rat brain.
Topics: Aging; Animals; Brain; Dehydroepiandrosterone; Enzyme Inhibitors; Male; Rats; Rats, Wistar; Sodium-P | 2008 |
The association between dehydroepiandosterone and frailty in older men and women.
Topics: Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Frail Elder | 2009 |
Circulating dehydroepiandrosterone sulfate concentrations during the menopausal transition.
Topics: Adult; Aging; Asian People; Black or African American; Cross-Sectional Studies; Dehydroepiandrostero | 2009 |
[Could serum DHEA and DHEAS levels be good risk predictors of metabolic syndrome and osteoporosis in the population of ageing men?].
Topics: Adult; Aged; Aged, 80 and over; Aging; Comorbidity; Dehydroepiandrosterone; Dementia; Humans; Hypert | 2009 |
Assessment of selected serum inflammatory markers of acute phase response and their correlations with adrenal androgens and metabolic syndrome in a population of men over the age of 40.
Topics: Acute-Phase Proteins; Adult; Age Factors; Aged; Aged, 80 and over; Aging; alpha 1-Antichymotrypsin; | 2009 |
Age-related effects of DHEA on peripheral markers of oxidative stress.
Topics: Age Factors; Aging; Animals; Catalase; Dehydroepiandrosterone; Erythrocytes; Glutathione Transferase | 2010 |
Depression-like behavior and reduced plasma testosterone levels in the senescence-accelerated mouse.
Topics: Acoustic Stimulation; Aging; Analysis of Variance; Animals; Behavior, Animal; Dehydroepiandrosterone | 2010 |
Dehydroepiandrosterone to enhance physical performance: myth and reality.
Topics: Adrenal Insufficiency; Aged; Aged, 80 and over; Aging; Anabolic Agents; Athletic Performance; Body C | 2010 |
Salivary glands - "an unisex organ'?
Topics: Aging; Androstenedione; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; Humans; Male; Preg | 2010 |
DHEA, important source of sex steroids in men and even more in women.
Topics: Adrenal Glands; Age Factors; Aging; Anticarcinogenic Agents; Brain; Breast; Cardiovascular Diseases; | 2010 |
Dehydroepiandrosterone intake protects against 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in the obese Zucker rat model.
Topics: Aging; Animals; Benz(a)Anthracenes; Body Weight; Carcinogens; Carcinoma, Ductal, Breast; Cytoprotect | 2010 |
Dehydroepiandrosterone effects on Akt signaling modulation in central nervous system of young and aged healthy rats.
Topics: Adjuvants, Immunologic; Aging; Animals; Dehydroepiandrosterone; Hippocampus; Hypothalamus; Male; Pro | 2010 |
Redox imbalance influence in the myocardial Akt activation in aged rats treated with DHEA.
Topics: Aging; Animals; Dehydroepiandrosterone; Glutathione Disulfide; Glutathione Peroxidase; Glutathione T | 2010 |
Defining ovarian reserve to better understand ovarian aging.
Topics: Adult; Aging; Dehydroepiandrosterone; Female; Fragile X Mental Retardation Protein; Humans; Middle A | 2011 |
Age-related changes in plasma dehydroepiandrosterone levels in adults with Down's syndrome and the risk of dementia.
Topics: Adult; Age Factors; Aged; Aging; Dehydroepiandrosterone; Dementia; Down Syndrome; Female; Humans; Mi | 2011 |
Differential influence of peripheral and systemic sex steroids on skeletal muscle quality in pre- and postmenopausal women.
Topics: Adult; Aged; Aging; Androstenedione; Anthropometry; Cohort Studies; Dehydroepiandrosterone; Female; | 2011 |
The effects of aging on the central nervous system steroid profiles and myelin basic protein in rats.
Topics: Aging; Animals; Central Nervous System; Dehydroepiandrosterone; Estradiol; Immunohistochemistry; Mal | 2012 |
The moderating impact of lifestyle factors on sex steroids, sexual activities and aging in Asian men.
Topics: Adipose Tissue; Adult; Aged; Aging; Alcohol Drinking; Asian People; Dehydroepiandrosterone; Dehydroe | 2011 |
Perimenopausal regulation of steroidogenesis in the nonhuman primate.
Topics: Aging; Animals; Biomarkers; Dehydroepiandrosterone; Estradiol; Female; Hippocampus; Hydrocortisone; | 2012 |
DHEA and estradiol levels in brain, gonads, adrenal glands, and plasma of developing male and female European starlings.
Topics: Adrenal Glands; Age Factors; Aging; Animals; Brain; Dehydroepiandrosterone; Estradiol; Female; Gonad | 2011 |
Ageing, physical function, and the diurnal rhythms of cortisol and dehydroepiandrosterone.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Circadian Rhythm; Dehydroepiandrosterone | 2012 |
GABA(A) receptor modulation during adolescence alters adult ethanol intake and preference in rats.
Topics: Aging; Alcohol Drinking; Animals; Data Interpretation, Statistical; Dehydroepiandrosterone; Dose-Res | 2012 |
Hormone supplementation during aging: how much and when?
Topics: Aging; Androgens; Animals; Cognition; Cognition Disorders; Dehydroepiandrosterone; Hormones; Macaca | 2012 |
Dehydroepiandrosterone in the type 1 diabetes mellitus.
Topics: Adolescent; Adult; Age Factors; Aging; Blood Glucose; Dehydroepiandrosterone; Dehydroepiandrosterone | 2012 |
Reduced neutrophil superoxide production among healthy older adults in response to acute psychological stress.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Blood Pressure; Dehydroepiandrosterone; Enzyme | 2012 |
The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats.
Topics: Acetylcysteine; Aging; Animals; Antioxidants; Biomarkers; Body Weight; Dehydroepiandrosterone; Growt | 2012 |
Cortisol, dehydroepiandrosterone sulfate, and androstenedione levels in patients with polymyalgia rheumatica during twelve months of glucocorticoid therapy.
Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aged; Aging; Androsten | 2002 |
DHEA: the last elixir.
Topics: Adjuvants, Immunologic; Adrenal Insufficiency; Age Factors; Aged; Aging; Clinical Trials as Topic; D | 2002 |
[DHEA and rejuvenating intracrinology? Between reason and magic].
Topics: Adjuvants, Immunologic; Aged; Aging; Dehydroepiandrosterone; Dermatitis, Seborrheic; Female; Humans; | 2002 |
Apolipoprotein E gene determines serum testosterone and dehydroepiandrosterone levels in postmenopausal women.
Topics: Aged; Aging; Apolipoprotein E4; Apolipoproteins E; Cross-Sectional Studies; Dehydroepiandrosterone; | 2002 |
Cortisol, DHEA, the Holy Grail and the fountain of youth.
Topics: Aged; Aging; Dehydroepiandrosterone; Humans; Hydrocortisone | 2002 |
Changes in peripheral blood lymphocyte subsets in elderly subjects are associated with an impaired function of the hypothalamic-pituitary-adrenal axis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Aging; Androstenedione; CD4-Positive T-Lymp | 2002 |
Endogenous hormones and carotid atherosclerosis in elderly men.
Topics: Aged; Aged, 80 and over; Aging; Arteriosclerosis; Carotid Artery Diseases; Case-Control Studies; Deh | 2003 |
Adrenopause: an imbalance between dehydroepiandrosterone (DHEA) and cortisol secretion.
Topics: Adrenal Cortex Hormones; Aged; Aging; Dehydroepiandrosterone; Hormone Replacement Therapy; Humans; H | 2002 |
On call. My wife and I are both 62 and healthy. She started taking Prempro during her menopause eight years ago but has now decided to stop the hormones. I began taking DHEA five years ago, but I switched to AndroGel when my doctor gave me a prescription
Topics: Aging; Bone Density; Cardiovascular Diseases; Dehydroepiandrosterone; Female; Hormone Replacement Th | 2003 |
[Anti-aging or better aging: a contribution to the prevention of aging?].
Topics: Aging; Dehydroepiandrosterone; Female; Genetic Testing; Hormones; Humans; Menopause | 2003 |
[Adrenopause and dehydroepiandrosterone: pharmacological therapy versus replacement therapy].
Topics: Adrenal Insufficiency; Aged; Aging; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone | 2003 |
In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients.
Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Androstenediol; | 2003 |
Dehydroepiandrosterone and androsterone levels in human plasma: effect of age and sex; day-to-day and diurnal variations.
Topics: Aging; Androgens; Androsterone; Circadian Rhythm; Dehydroepiandrosterone; Humans; Sex Characteristic | 1957 |
The urinary excretion of dehydroepiandrosterone and total 17-ketosteroids in aged men and women.
Topics: 17-Ketosteroids; Aging; Androgens; Body Fluids; Dehydroepiandrosterone; Hormones; Humans; Male | 1957 |
SIMULTANEOUS DETERMINATION OF 17-OXOSTEROIDS AND 17-HYDROXY-CORTICOSTEROIDS IN PLASMA FROM NORMAL WOMEN.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aging; Androsterone; Blood Chemical Analysis; Body Height; | 1964 |
EFFECT OF CASTRATION IN MAN UPON BLOOD SEDIMENTATION RATE, HEMATOCRIT AND HEMOGLOBIN.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Aging; Androsterone; Biomedical Research; Bl | 1964 |
SYNTHESIS OF STEROIDS IN THE NEWBORN HUMAN ADRENAL IN VITRO.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Aging; Carbon Isotopes; Corti | 1965 |
[Investigation, treatment and monitoring of late-onset hypogonadism in males: the official guidelines of the International Society for the Study of the Study of the Aging Male (ISSAM) with comments].
Topics: Aging; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; France; Hormones; Human Gr | 2003 |
Elevated sex-hormone binding globulin in elderly women with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Apolipoprotein E4; Apolipop | 2004 |
Effect of DHEA glutamate release from synaptosomes of rats at different ages.
Topics: Aging; Animals; Brain; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Excitatory Amino Ac | 2004 |
Physiological significance of replacement therapy of dehydroepiandrosterone.
Topics: Aging; Dehydroepiandrosterone; Hormone Replacement Therapy; Humans | 2004 |
DHEA treatment of Alzheimer's disease: A randomized, double-blind, placebo-controlled trial.
Topics: Age Factors; Aged; Aging; Alzheimer Disease; Dehydroepiandrosterone; Double-Blind Method; Female; Hi | 2004 |
Polycythemia in a physician secondary to self-administered growth hormone, testosterone, and dehydroepiandrosterone to prevent aging.
Topics: Aged; Aging; Dehydroepiandrosterone; Hormone Replacement Therapy; Human Growth Hormone; Humans; Male | 2004 |
An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD.
Topics: Adrenal Glands; Adult; Aging; Behavior; Cosyntropin; Dehydroepiandrosterone; Dehydroepiandrosterone | 2004 |
Cognitive and affective disorders in the elderly: a neuroendocrine study.
Topics: Aged; Aged, 80 and over; Aging; Circadian Rhythm; Cognition Disorders; Comorbidity; Dehydroepiandros | 2004 |
Ex vivo studies on the acute and chronic effects of DHEA and DHEA-sulfate on melatonin synthesis in young- and old-rat pineal glands.
Topics: Acetylserotonin O-Methyltransferase; Aging; Animals; Arylamine N-Acetyltransferase; Darkness; Dehydr | 2004 |
Expression of cytochrome P450c17 and other steroid-converting enzymes in the rat kidney throughout the life-span.
Topics: 3-Hydroxysteroid Dehydrogenases; Aging; Androgens; Androstenes; Animals; Animals, Newborn; Azasteroi | 2004 |
Neuroendocrine hypothesis of aging: the role of corticoadrenal steroids.
Topics: Adrenal Cortex Hormones; Aging; Dehydroepiandrosterone; Humans; Hydrocortisone; Hypothalamo-Hypophys | 2004 |
Age-related decline in RACK-1 expression in human leukocytes is correlated to plasma levels of dehydroepiandrosterone.
Topics: Adult; Aged; Aging; Animals; Cell Proliferation; Dehydroepiandrosterone; Female; GTP-Binding Protein | 2005 |
Testicular and blood steroid levels in aged men.
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; F | 2004 |
Adrenal androgens in human physiology.
Topics: Adrenal Glands; Aging; Androgens; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; F | 2004 |
Age-related expression of sigma1 receptors and antidepressant efficacy of a selective agonist in the senescence-accelerated (SAM) mouse.
Topics: Age Factors; Aging; Animals; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Blotting | 2005 |
[The mechanism of skeletal muscle aging].
Topics: Adult; Aged; Aged, 80 and over; Aging; Atrophy; Dehydroepiandrosterone; Humans; Insulin-Like Growth | 2004 |
Are dehydroepiandrosterone sulphate and lipids associated with erectile dysfunction?
Topics: Adolescent; Adult; Aged; Aging; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LD | 2005 |
Age, hormones, and cognitive functioning among middle-aged and elderly men: cross-sectional evidence from the Massachusetts Male Aging Study.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Androgens; Blood Chemical Analysis; Cognition; Cognitio | 2005 |
Dehydroepiandrosterone (DHEA).
Topics: Adjuvants, Immunologic; Adolescent; Adrenal Insufficiency; Adult; Aging; Alzheimer Disease; Dehydroe | 2005 |
Anti-lipidperoxidative role of exogenous dehydroepiendrosterone (DHEA) administration in normal ageing rat brain.
Topics: Aging; Animals; Brain; Dehydroepiandrosterone; Lipid Peroxidation; Male; Rats; Rats, Wistar | 2005 |
Tibolone, transdermal estradiol or oral estrogen-progestin therapies: effects on circulating allopregnanolone, cortisol and dehydroepiandrosterone levels.
Topics: Administration, Cutaneous; Adrenal Glands; Aging; Dehydroepiandrosterone; Estradiol; Estrogen Replac | 2005 |
Sex steroid metabolism in human peripheral blood mononuclear cells changes with aging.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Aged; Aging; Cholestenone 5 alpha-Reductase; Cross-Sectiona | 2005 |
Alterations in DHEA metabolism in schizophrenia: two-month case-control study.
Topics: Adult; Aging; Androstenedione; Antipsychotic Agents; Anxiety; Case-Control Studies; Dehydroepiandros | 2006 |
Dehydroepiandrosterone restoration of growth hormone gene expression in aging female rats, in vivo and in vitro: evidence for actions via estrogen receptors.
Topics: Aging; Aminoglutethimide; Animals; Aromatase Inhibitors; Cells, Cultured; Dehydroepiandrosterone; Di | 2005 |
Plasma levels of 7-hydroxymetabolites of dehydroepiandrosterone in healthy Central European aging men.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Health; Humans; Logistic | 2005 |
The sex steroid precursor DHEA accelerates cutaneous wound healing via the estrogen receptors.
Topics: Aging; Animals; Aromatase; Chronic Disease; Cytokines; Dehydroepiandrosterone; Female; Gonadal Stero | 2005 |
DHEA supplements. Benefits are promising, but proof is lacking.
Topics: Adjuvants, Immunologic; Aging; Dehydroepiandrosterone; Humans | 2005 |
Dehydroepiandrosterone increases beta-cell mass and improves the glucose-induced insulin secretion by pancreatic islets from aged rats.
Topics: Adjuvants, Immunologic; Aging; Animals; Cell Size; Dehydroepiandrosterone; Diabetes Mellitus; Humans | 2006 |
Treatment with dehydroepiandrosterone (DHEA) stimulates oxidative energy metabolism in the cerebral mitochondria. A comparative study of effects in old and young adult rats.
Topics: Adenosine Triphosphatases; Adjuvants, Immunologic; Age Factors; Aging; Animals; Cerebral Cortex; Cyt | 2006 |
Serum profiles of free and conjugated neuroactive pregnanolone isomers in nonpregnant women of fertile age.
Topics: Adult; Aging; Dehydroepiandrosterone; Estradiol; Female; Follicular Phase; Gas Chromatography-Mass S | 2006 |
Aging and fountain-of-youth hormones.
Topics: Adult; Aged; Aging; Body Composition; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; H | 2006 |
Consensus Document on substitution therapy with DHEA in the elderly.
Topics: Adult; Aged; Aged, 80 and over; Aging; Atherosclerosis; Bone Diseases, Metabolic; Cognition Disorder | 2006 |
Healthy aging is associated with unaltered production of immunoreactive growth hormone but impaired neuroimmunomodulation.
Topics: Aged; Aged, 80 and over; Aging; Area Under Curve; Cell Proliferation; Cells, Cultured; Dehydroepiand | 2006 |
Hypoxia and dehydroepiandrosterone in old age: a mouse survival study.
Topics: Adjuvants, Immunologic; Aging; Animals; Dehydroepiandrosterone; Hypoxia; Longevity; Mice; Mice, Inbr | 2006 |
Age-dependent regulation of chromaffin cell proliferation by growth factors, dehydroepiandrosterone (DHEA), and DHEA sulfate.
Topics: Aging; Animals; Cattle; Cell Proliferation; Cells, Cultured; Chromaffin Cells; Dehydroepiandrosteron | 2007 |
DHEA and testosterone in the elderly.
Topics: Aged; Aging; Andropause; Body Composition; Bone Density; Dehydroepiandrosterone; Hormone Replacement | 2007 |
DHEA and testosterone in the elderly.
Topics: Aged; Aging; Dehydroepiandrosterone; Dietary Supplements; Drug Approval; Female; Hormone Replacement | 2007 |
DHEA and testosterone in the elderly.
Topics: Aged; Aging; Body Composition; Dehydroepiandrosterone; Exercise; Hormone Replacement Therapy; Humans | 2007 |
DHEA and testosterone in the elderly.
Topics: Aged; Aging; Dehydroepiandrosterone; Estradiol; Female; Hormone Replacement Therapy; Humans; Male; M | 2007 |
DHEA offers little benefit in preventing bodily changes related to age.
Topics: Adjuvants, Immunologic; Aged; Aging; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Trea | 2007 |
Research on the age-related changes in the nitric oxide pathway in the arteries of rats and the intervention effect of dehydroepiandrosterone.
Topics: Adjuvants, Immunologic; Aging; Animals; Aorta, Thoracic; Dehydroepiandrosterone; Endothelium, Vascul | 2007 |
DHEA and health: more questions than answers.
Topics: Aging; Cognition; Coronary Artery Disease; Dehydroepiandrosterone; Depression; Dietary Supplements; | 2007 |
Sex differences in the relationship between DHEAS and health.
Topics: Aged; Aging; Asian People; Biomarkers; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiandros | 2007 |
[Prevention and anti-aging in endocrinology].
Topics: Aged; Aging; Dehydroepiandrosterone; Estrogen Replacement Therapy; Female; Hormone Replacement Thera | 2007 |
Effect of aging and reproductive condition on dehydroepiandrosterone plasma levels in the bitch.
Topics: Aging; Animals; Dehydroepiandrosterone; Dogs; Estrous Cycle; Female; Ovariectomy; Reproduction | 2007 |
Aging effects on the mongolian gerbil female prostate (Skene's paraurethral glands): structural, ultrastructural, quantitative, and hormonal evaluations.
Topics: Aging; Animals; Dehydroepiandrosterone; Estradiol; Exocrine Glands; Female; Gonadal Steroid Hormones | 2008 |
Effect of dehydroepiandrosterone (DHEA) on monoamine oxidase activity, lipid peroxidation and lipofuscin accumulation in aging rat brain regions.
Topics: Age Factors; Aging; Animals; Antioxidants; Brain; Dehydroepiandrosterone; Injections, Intraperitonea | 2008 |
CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling.
Topics: Aging; Androstane-3,17-diol; Animals; Cell Line; Cytochrome P-450 Enzyme System; Dehydroepiandroster | 2008 |
Dehydroepiandrosterone prevents age-associated alterations, increasing insulin sensitivity.
Topics: Adipocytes; Adiponectin; Aging; Animals; Appetite; Body Weight; Dehydroepiandrosterone; Energy Intak | 2008 |
A radioimmunoassay for dehydroepiandrosterone sulfate in the circulation of rhesus monkeys.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Animals, Newborn; Chromatography; Cross Reactions; Dehy | 1983 |
DHEA: "miracle" drug?
Topics: Adrenal Glands; Adult; Aged; Aging; Animals; Breast Neoplasms; Colonic Neoplasms; Dehydroepiandroste | 1982 |
Plasma androgens in children and adolescents. Part I: control subjects.
Topics: Adolescent; Adult; Aging; Androgens; Androstenedione; Body Surface Area; Child; Child, Preschool; Cr | 1982 |
Follicular and plasma patterns of steroids in young and old rats during normal and prolonged estrous cycles.
Topics: Aging; Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Estrone; Estrus; Female; Gonadal | 1982 |
Effect of food restriction, dehydroepiandrosterone, or obesity on the binding of 3H-7,12-dimethylbenz(a)anthracene to mouse skin DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone; DNA; F | 1983 |
Developmental patterns of serum luteinizing hormone, gonadal and adrenal steroids in the sooty mangabey (Cercocebus atys).
Topics: Aging; Androstenedione; Animals; Body Weight; Cercopithecidae; Dehydroepiandrosterone; Female; Haplo | 1983 |
Early menarche, a risk factor for breast cancer, indicates early onset of ovulatory cycles.
Topics: Adolescent; Aging; Breast Neoplasms; Child; Dehydroepiandrosterone; Estradiol; Female; Follicle Stim | 1983 |
Hormonal aspects of human gout--excretion of adrenal hormone derivatives in gouty patients.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aging; Allopurinol; Androsterone; Dehydroepiandrosterone; Etio | 1983 |
Androgen secretion after age 50 in both sexes.
Topics: Adrenal Glands; Aged; Aging; Androgens; Chorionic Gonadotropin; Dehydroepiandrosterone; Female; Huma | 1983 |
A mixed longitudinal study of adrenal steroid excretion in childhood and the mechanism of adrenarche.
Topics: 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Aging; Aldehyd | 1983 |
[Characteristics of the androgenic function of steroid-producing glands of baboons in the metapyrone test].
Topics: Aging; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Papio; Pyridines; Test | 1983 |
Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice.
Topics: Aging; Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; Diabetes Mellitus; Female; Gluco | 1984 |
Androgen plasma levels in male diabetics.
Topics: Adult; Aging; Androgens; Dehydroepiandrosterone; Diabetes Complications; Diabetes Mellitus; Erectile | 1984 |
Comparison of the effects of DHEA and food restriction on serum calcitonin.
Topics: Aging; Animals; Body Weight; Calcitonin; Dehydroepiandrosterone; Female; Food Deprivation; Rats; Rat | 1984 |
Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood.
Topics: Adolescent; Adult; Aged; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1984 |
The interrelationship between plasma 5-ene adrenal androgens in normal women.
Topics: Adult; Aged; Aging; Androstenediol; Androstenediols; Dehydroepiandrosterone; Dehydroepiandrosterone | 1984 |
Decreased adrenal androgen sensitivity to ACTH during aging.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Aldosterone; Androstenedione; Cosyn | 1981 |
Adrenocortical function in old age: response to acute adrenocorticotropin stimulation.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aged; | 1982 |
Proopiocortin-related peptide plasma levels throughout prepuberty and puberty.
Topics: Adolescent; Adrenocorticotropic Hormone; Aging; beta-Endorphin; beta-Lipotropin; Child; Child, Presc | 1983 |
Pattern of plasma pregnenolone sulfate levels in humans from birth to adulthood.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aging; Child; Child, Preschool; Chorionic Gonadotrop | 1983 |
Endocrine and behavioral modifications in aging male rats.
Topics: Adrenal Glands; Aging; Animals; Behavior, Animal; Brain; Corticosterone; Dehydroepiandrosterone; Est | 1980 |
Testicular and adrenal androgens and their binding to plasma proteins in the perinatal period: developmental patterns of plasma testosterone, 4-androstenedione, dehydroepiandrosterone and its sulfate in premature and small for date infants as compared wit
Topics: Adrenal Glands; Aging; Androgen-Binding Protein; Androgens; Androstenedione; Carrier Proteins; Dehyd | 1980 |
Urinary excretion of androgen metabolites, comparison with excretion of radioactive metabolites after injection of [4-14C]testosterone. Influence of age.
Topics: Adolescent; Adult; Aged; Aging; Androgens; Androstane-3,17-diol; Androstenedione; Androsterone; Chem | 1981 |
Female runners and secondary amenorrhea: correlation with age, parity, mileage, and plasma hormonal and sex-hormone-binding globulin concentrations.
Topics: Adipose Tissue; Adolescent; Adult; Aging; Amenorrhea; Androgens; Dehydroepiandrosterone; Estrogens; | 1981 |
Age and sex differences in the metabolism of C19-delta5-steroids in human amniotic epithelium.
Topics: Aging; Amnion; Androstenediols; Dehydroepiandrosterone; Epithelium; Female; Humans; Pregnancy; Pregn | 1980 |
Pubertal endocrinology of the baboon: adrenarche.
Topics: Aging; Androstenedione; Animals; Dehydroepiandrosterone; Female; Hydrocortisone; Male; Papio; Radioi | 1981 |
Circulating LH, FSH, prolactin, testosterone, delta 4-androstenedione, dehydroepiandrosterone sulfate and cortisol levels in the fetus in late gestation and in newborn male and female lambs.
Topics: Aging; Androgens; Androstenedione; Animals; Animals, Newborn; Dehydroepiandrosterone; Dehydroepiandr | 1981 |
The aging Leydig cell V. Diurnal rhythms in aged men.
Topics: Adult; Age Factors; Aged; Aging; Androstenedione; Chromatography; Circadian Rhythm; Dehydroepiandros | 1982 |
DHEAS enhances germinal center responses in old mice.
Topics: Adjuvants, Immunologic; Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fema | 1994 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women.
Topics: Adult; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Huma | 1995 |
The age of dehydroepiandrosterone.
Topics: Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans | 1995 |
Dehydroepiandrosterone, dehydroepiandrosterone sulphate, and their relation to cortisol in red deer (Cervus elaphus).
Topics: Adrenal Glands; Aging; Animals; Animals, Newborn; Deer; Dehydroepiandrosterone; Dehydroepiandrostero | 1994 |
Association between calcium regulatory hormones and other factors and bone mineral density in elderly Chinese men and women.
Topics: 25-Hydroxyvitamin D 2; Aged; Aging; Antihypertensive Agents; Body Mass Index; Bone and Bones; Bone D | 1994 |
The development of effective vaccine adjuvants employing natural regulators of T-cell lymphokine production in vivo.
Topics: Adjuvants, Immunologic; Administration, Topical; Aging; Animals; Antibody Formation; Dehydroepiandro | 1994 |
[Age-related characteristics of the regulation of the dehydroepiandrosterone sulfate level in the peripheral blood plasma of monkeys].
Topics: Adrenal Cortex; Aging; Animals; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sul | 1993 |
Age- and microenvironment-associated influences by platelet-derived growth factor on T cell function.
Topics: Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Interleukin-6; Lymph | 1994 |
Decreased testosterone and dehydroepiandrosterone sulfate concentrations are associated with increased insulin and glucose concentrations in nondiabetic men.
Topics: Adult; Aging; Anthropometry; Blood Glucose; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1994 |
Hormonal factors and prognosis in epithelial ovarian cancer: a multivariate analysis.
Topics: Adenocarcinoma; Adenocarcinoma, Clear Cell; Adenocarcinoma, Mucinous; Aging; Androstenedione; Carcin | 1993 |
Dehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins.
Topics: Adult; Aging; Anovulation; Cell Count; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Femal | 1994 |
Relationship of body fat percentage and fat distribution with dehydroepiandrosterone sulfate in premenopausal females.
Topics: Adipose Tissue; Adult; Aging; Body Composition; Body Mass Index; Dehydroepiandrosterone; Dehydroepia | 1993 |
Senescent decline in serum dehydroepiandrosterone sulfate concentrations in a population of wild baboons.
Topics: Aging; Animals; Animals, Wild; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Kenya | 1993 |
Role of dehydroepiandrosterone and dehydroepiandrosterone sulfate for the maintenance of axillary hair in women.
Topics: Adolescent; Adult; Aged; Aging; Axilla; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fema | 1993 |
Serum levels of adrenal androgens up to adrenarche in Peruvian children living at sea level and at high altitude.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aging; Altitude; Androstenedione; Child; Dehydroepiandroste | 1993 |
Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative.
Topics: Aged; Aged, 80 and over; Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fem | 1993 |
[Effect of sex steroids on serum amyloid P-component (female protein) in rats].
Topics: Aging; Animals; Cricetinae; Dehydroepiandrosterone; Estradiol; Female; Immunodiffusion; Male; Rabbit | 1995 |
Dehydroepiandrosterone (DHEA) treatment reverses the impaired immune response of old mice to influenza vaccination and protects from influenza infection.
Topics: Adjuvants, Immunologic; Aging; Animals; Antibodies, Viral; Dehydroepiandrosterone; Drug Therapy, Com | 1995 |
Dehydroepiandrosterone sulphate in the diagnosis of osteoporosis.
Topics: Absorptiometry, Photon; Aged; Aging; Biomarkers; Bone Density; Dehydroepiandrosterone; Dehydroepiand | 1995 |
Dehydroepiandrosterone sulfate in a long-term care aged population.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydr | 1995 |
Dehydroepiandrosterone (DHEA) and Aging. Proceedings of a conference. Washington, D.C., June 17-19, 1995.
Topics: Aging; Animals; Dehydroepiandrosterone; Humans | 1995 |
Metabolism of dehydroepiandrosterone.
Topics: Adult; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Insulin; Male; | 1995 |
Relationship between humoral immunoaugmenting properties of DHEAS and IgD-receptor expression in young and aged mice.
Topics: Adjuvants, Immunologic; Aging; Animals; Antibody Formation; Dehydroepiandrosterone; Dehydroepiandros | 1995 |
Dehydroepiandrosterone enhances influenza immunization in aged mice.
Topics: Aging; Animals; Antibodies, Viral; Dehydroepiandrosterone; Female; Influenza Vaccines; Mice; Mice, I | 1995 |
Effects of aging and long-term calorie restriction on DHEA and DHEA sulfate in rhesus monkeys.
Topics: Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Energy Intake; Female; Macac | 1995 |
Antidepressant and cognition-enhancing effects of DHEA in major depression.
Topics: Affect; Aged; Aging; Cognition; Dehydroepiandrosterone; Depression; Female; Humans; Male; Middle Age | 1995 |
Effect of dehydroepiandrosterone on rat thyroxine binding globulin, a protein upregulated during aging.
Topics: Aging; Animals; Dehydroepiandrosterone; Male; Prealbumin; Rats; Rats, Wistar; Thyroxine-Binding Prot | 1995 |
Regulation of human dehydroepiandrosterone metabolism by insulin.
Topics: Adrenal Glands; Adult; Aged; Aging; Aldehyde-Lyases; Cytochrome P-450 Enzyme System; Dehydroepiandro | 1995 |
Hormone replacement for men.
Topics: Aging; Attitude to Health; Controlled Clinical Trials as Topic; Dehydroepiandrosterone; Humans; Male | 1996 |
Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males.
Topics: Adult; Aged; Aged, 80 and over; Aging; Androgens; Body Mass Index; Dehydroepiandrosterone; Dehydroep | 1996 |
Relationship between serum dehydroepiandrosterone sulfate, androstenedione, and sex hormones in men and women.
Topics: Adult; Aged; Aging; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradi | 1996 |
Age effects of follicle-stimulating hormone and pulsatile luteinizing hormone secretion across the menstrual cycle of premenopausal women.
Topics: Adolescent; Adult; Age Factors; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estra | 1996 |
Immunocytochemical demonstration of androgen receptors in Leydig cells of the bank vole (Clethrionomys glareolus, Schreber): an in vitro study.
Topics: Aging; Animals; Antibodies; Arvicolinae; Cell Nucleus; Cytoplasm; Dehydroepiandrosterone; Fluorescen | 1996 |
[Change of serum amyloid P component concentrations in women].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Child; Child, Preschool; Dehydroepiandro | 1996 |
Scientific verdict still out on DHEA.
Topics: Aging; Animals; Cardiovascular System; Dehydroepiandrosterone; Food, Fortified; Humans; Immune Syste | 1996 |
Cortisol, dehydroepiandrosterone (DHEA), and DHEA sulfate in the cerebrospinal fluid of man: relation to blood levels and the effects of age.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Dehydroepiandrosterone; | 1996 |
[Clinical value of dehydroepiandrosterone and its sulfate ester].
Topics: Aged; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Health Status; Humans; | 1996 |
Promotion of interleukin-2 activity as a strategy for 'rejuvenating' geriatric immune function.
Topics: Aging; Animals; Antioxidants; Carotenoids; Chromium; Clonal Anergy; Dehydroepiandrosterone; Diet; HI | 1997 |
Super hype for super hormones.
Topics: Aged; Aging; Dehydroepiandrosterone; Food, Organic; Human Growth Hormone; Humans; Melatonin; Testost | 1997 |
Effects of hormone replacement therapy on serum amyloid P component in postmenopausal women.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arteriosclerosis; Biomarkers; | 1997 |
IL-6, DHEA and the ageing process.
Topics: Adult; Age Factors; Aged; Aging; Cells, Cultured; Dehydroepiandrosterone; Female; Humans; Interleuki | 1997 |
[Juvenile hormones, reality or myth?].
Topics: Aged; Aging; Animals; Dehydroepiandrosterone; Female; Humans; Life Expectancy; Male; Melatonin; Mice | 1997 |
Age and sex related differences in serum levels of unconjugated dehydroepiandrosterone and its sulphate in normal subjects.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Dehydroepia | 1997 |
Relationship of dehydroepiandrosterone and cortisol in disease.
Topics: Adrenal Cortex Hormones; Aging; Animals; Circadian Rhythm; Cushing Syndrome; Dehydroepiandrosterone; | 1997 |
Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Aged; Aged, 80 and over; Aging; Androgens; Androstenediol; | 1997 |
Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Aged; Aged, 80 and over; Aging; Androgens; Androstenediol; | 1997 |
Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Aged; Aged, 80 and over; Aging; Androgens; Androstenediol; | 1997 |
Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Aged; Aged, 80 and over; Aging; Androgens; Androstenediol; | 1997 |
DHEA--brass ring or red herring?
Topics: Adult; Aging; Animals; Clinical Trials as Topic; Dehydroepiandrosterone; Female; Humans; Male; Middl | 1997 |
Dehydroepiandrosterone administration reverses the inhibitory influence of aging on gonadotrophin-releasing hormone gene expression in the male and female rat brain.
Topics: Aging; Animals; Autoradiography; Brain; Cell Count; Cohort Studies; Dehydroepiandrosterone; Diestrus | 1997 |
Age-related decrease in the hypothalamic CRH mRNA expression is reduced by dehydroepiandrosterone (DHEA) treatment in male and female rats.
Topics: Aging; Animals; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Female; Hypothalamo-Hypophy | 1997 |
Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo Study.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Biological Availability; Body Mass Index; Bo | 1997 |
Aging and endocrinology.
Topics: Aging; Animals; Clinical Trials as Topic; Dehydroepiandrosterone; Drug Synergism; Female; Humans; Me | 1998 |
DHEA treatment reduces fat accumulation and protects against insulin resistance in male rats.
Topics: Adipose Tissue; Aging; Animals; Body Composition; Body Mass Index; Body Weight; Dehydroepiandrostero | 1998 |
DHEA treatment reduces fat accumulation and protects against insulin resistance in male rats.
Topics: Adipose Tissue; Aging; Animals; Body Composition; Body Mass Index; Body Weight; Dehydroepiandrostero | 1998 |
DHEA treatment reduces fat accumulation and protects against insulin resistance in male rats.
Topics: Adipose Tissue; Aging; Animals; Body Composition; Body Mass Index; Body Weight; Dehydroepiandrostero | 1998 |
DHEA treatment reduces fat accumulation and protects against insulin resistance in male rats.
Topics: Adipose Tissue; Aging; Animals; Body Composition; Body Mass Index; Body Weight; Dehydroepiandrostero | 1998 |
DHEA: elixir of youth or mirror of age?
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged | 1998 |
DHEA: a biologic conundrum.
Topics: Aging; Alzheimer Disease; Cardiovascular Diseases; Dehydroepiandrosterone; Erectile Dysfunction; Fem | 1998 |
Intra-adrenal factors are not involved in the differential control of cortisol and adrenal androgens in human adrenals.
Topics: Adolescent; Adrenal Glands; Adult; Aging; Androgens; Androstenedione; Child; Child, Preschool; Dehyd | 1998 |
Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man in vitro: possible link between endocrinosenescence and immunosenescence.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Androstenedione; Cells, Cultured; Dehydroepiandro | 1998 |
Circulating levels of allopregnanolone in humans: gender, age, and endocrine influences.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aged; Aging; Corticotropin-Releasing Hormone; De | 1998 |
DHEA: will science confirm the headlines?
Topics: Adult; Aged; Aging; Animals; Child; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Rejuv | 1998 |
Increased diurnal plasma concentrations of dehydroepiandrosterone in depressed patients.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Body Mass Index; Circadian Rhythm; Dehydroepiandros | 1998 |
Effect of dehydroepiandrosterone (DHEA) on intestinal mucosal immunity in young adult and aging rats.
Topics: Adjuvants, Immunologic; Aging; Animals; Antibodies, Bacterial; Antibody Formation; Bile; Body Weight | 1998 |
Adrenarche results from development of a 3beta-hydroxysteroid dehydrogenase-deficient adrenal reticularis.
Topics: 17-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Glands; Adult; Aging; Child; Child, Preschool; | 1998 |
Dehydroepiandrosterone: dream or nightmare?
Topics: Affect; Aging; Cognition; Dehydroepiandrosterone; Humans | 1998 |
Dehydroepiandrosterone (DHEA) ameliorates the insulin sensitivity in older rats.
Topics: Aging; Animals; Body Weight; Dehydroepiandrosterone; Feeding Behavior; Insulin; Insulin Resistance; | 1998 |
Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage.
Topics: Adjuvants, Immunologic; Aged; Aging; Alzheimer Disease; Animals; Cells, Cultured; Dehydroepiandroste | 1999 |
Anti-aging hormones.
Topics: Aging; Dehydroepiandrosterone; Estrogens; Human Growth Hormone; Humans; Melatonin; Testosterone | 1999 |
Dehydro-epiandrosterone and ageing.
Topics: Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Glucose; Humans; Insulin | 1999 |
DHEA: mood, memory, and aging.
Topics: Adjuvants, Immunologic; Adult; Affect; Aged; Aging; Dehydroepiandrosterone; Female; Humans; Male; Me | 1999 |
Assessing dehydroepiandrosterone in saliva: a simple radioimmunoassay for use in studies of children, adolescents and adults.
Topics: Adolescent; Adult; Aging; Child; Circadian Rhythm; Dehydroepiandrosterone; Female; Humans; Male; Rad | 1999 |
Modification of physical movement in old C57BL/6 mice by DHEA and melatonin supplementation.
Topics: Age Factors; Aging; Animals; Behavior, Animal; Dehydroepiandrosterone; Female; Locomotion; Melatonin | 1999 |
Induction of endogenous coenzyme Q biosynthesis by administration of peroxisomal inducers.
Topics: Aging; Animals; Aspirin; Clofibrate; Dehydroepiandrosterone; Diethylhexyl Phthalate; Intracellular M | 1999 |
Effects of ageing and dehydroepiandrosterone administration on pro-opiomelanocortin mRNA expression in the anterior and intermediate lobes of the rat pituitary.
Topics: Aging; Animals; Dehydroepiandrosterone; Female; Male; Pituitary Gland; Pituitary Gland, Anterior; Pr | 1999 |
The influence of age and gender on serum dehydroepiandrosterone sulphate (DHEA-S), IL-6, IL-6 soluble receptor (IL-6 sR) and transforming growth factor beta 1 (TGF-beta1) levels in normal healthy blood donors.
Topics: Adolescent; Adult; Aged; Aging; Blood Donors; Dehydroepiandrosterone; Female; Humans; Interleukin-6; | 1999 |
Correlation between the administered dose of DHEA and serum levels of DHEA and DHEA-S in human volunteers: analysis of published data.
Topics: Adolescent; Adult; Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Resp | 1999 |
Dehydroepiandrosterone for adrenal insufficiency.
Topics: Adrenal Insufficiency; Aged; Aging; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; Humans | 1999 |
Changes with aging of steroidal levels in the cerebrospinal fluid of women.
Topics: Adolescent; Adult; Aged; Aging; Central Nervous System; Dehydroepiandrosterone; Dehydroepiandrostero | 1999 |
DHEA: efficacy supported by testing and model studies.
Topics: Aging; Animals; Dehydroepiandrosterone; Dietary Supplements; Humans; Male | 1999 |
The effect of 7-oxo-DHEA acetate on memory in young and old C57BL/6 mice.
Topics: Aging; Animals; Dehydroepiandrosterone; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Musca | 2000 |
Evaluation of the circadian profiles of serum dehydroepiandrosterone (DHEA), cortisol, and cortisol/DHEA molar ratio after a single oral administration of DHEA in elderly subjects.
Topics: Administration, Oral; Adult; Aged; Aging; Circadian Rhythm; Dehydroepiandrosterone; Female; Humans; | 2000 |
Characterization of exogenous testosterone in livestock by gas chromatography/combustion/isotope ratio mass spectrometry: influence of feeding and age.
Topics: Aging; Animal Feed; Animals; Cattle; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; E | 2000 |
Characterization of serum dehydroepiandrosterone secretion in golden hamsters.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aging; Analysis of Variance; Animals; Ci | 2000 |
Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study.
Topics: Aging; Animals; Behavior, Animal; Blood Glucose; Body Composition; Body Weight; Bone Density; Dehydr | 2000 |
Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men.
Topics: Adolescent; Adult; Aged; Aging; Androgens; Androstenedione; Dehydroepiandrosterone; Feedback; Follic | 2001 |
Low dehydroepiandrosterone and ischemic heart disease in middle-aged men: prospective results from the Massachusetts Male Aging Study.
Topics: Adult; Aged; Aging; Cohort Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; | 2001 |
Profile. For 'father' of abortion drug, vindication at last.
Topics: Abortifacient Agents, Steroidal; Aging; Dehydroepiandrosterone; Drug Approval; Drug Industry; Female | 2000 |
[Aging without becoming old. 2 anti-aging days per week].
Topics: Adult; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Fasting; Female; Growth Hormone; Heal | 2001 |
Symposium on endocrinology and aging: the 1st meeting of the European Interest Group hormones and aging.
Topics: Adrenal Glands; Aging; Dehydroepiandrosterone; Endocrine Glands; Endocrinology; Europe; Geriatrics; | 2001 |
DHEA and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aging; Dehydroepiandrosterone; Dehydroepiandrostero | 1996 |
Upregulation of the klotho gene expression by thyroid hormone and during adipose differentiation in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Aging; Animals; Cell Differentiation; Cell Membrane; Dehydroepiandrosterone; | 2001 |
Can skin wrinkling in a site that has received limited sun exposure be used as a marker of health status and biological age?
Topics: Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Geriatric A | 2001 |
Dehydroepiandrosterone in songbird plasma: seasonal regulation and relationship to territorial aggression.
Topics: Adrenal Glands; Aggression; Aging; Animals; Breeding; Dehydroepiandrosterone; Dehydroepiandrosterone | 2001 |
Reduction in DNA damage in brain and peripheral blood lymphocytes of elderly dogs after treatment with dehydroepiandrosterone (DHEA).
Topics: Administration, Oral; Aging; Animals; Brain; Comet Assay; Dehydroepiandrosterone; DNA; DNA Damage; D | 2001 |
Testosterone, dehydroepiandrosterone, insulin-like growth factor 1, and insulin in sedentary and physically trained aged men.
Topics: Aged; Aging; Body Mass Index; Dehydroepiandrosterone; Exercise; Humans; Insulin; Insulin-Like Growth | 2001 |
DHEA: hope or hype?
Topics: Adult; Aging; Dehydroepiandrosterone; Female; Humans; Male | 2001 |
Effect of low birth weight on adrenal steroids and carbohydrate metabolism in early adulthood.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adult; Aging; Androstenedione; Carbohydrate Metabolism | 2001 |
Dehydroepiandrosterone, ageing and immune activation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 2001 |
7-Hydroxydehydroepiandrosterone epimers in the life span.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Dehydroepiandrosterone; Female; Humans; Li | 2001 |
Age-related differences in features associated with polycystic ovary syndrome in normogonadotrophic oligo-amenorrhoeic infertile women of reproductive years.
Topics: Adolescent; Adult; Aging; Amenorrhea; Androstenedione; Body Constitution; Body Mass Index; Cross-Sec | 2001 |
[DHEA, osteoporosis, nuclear receptor and aging].
Topics: Administration, Oral; Aged; Aging; Bone and Bones; Dehydroepiandrosterone; Female; Humans; Male; Mid | 2001 |
Dehydroepiandosterone and its sulphate enhance memory retention in day-old chicks.
Topics: Aging; Animals; Animals, Newborn; Avoidance Learning; Brain; Chickens; Dehydroepiandrosterone; Dehyd | 2002 |
In vivo dehydroepiandrosterone restores age-associated defects in the protein kinase C signal transduction pathway and related functional responses.
Topics: Aging; Animals; Blotting, Western; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone S | 2002 |
Adrenopause or decline of serum adrenal androgens with age in women living at sea level or at high altitude.
Topics: Adrenal Glands; Adult; Aged; Aging; Altitude; Androgens; Androstenedione; Cross-Sectional Studies; D | 2002 |
Steroid sulfatase in brain: comparison of sulfohydrolase activities for various steroid sulfates in normal and pathological brains, including the various forms of metachromatic leukodystrophy.
Topics: Aging; Animals; Arylsulfatases; Brain; Cholesterol; Dehydroepiandrosterone; Detergents; Estrone; Fem | 1976 |
In vitro testosterone synthesis by testicular tissue of old mouse: the metabolism of 3beta-hydroxy-5-ene steroids.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Androgens; Androstenediols; Androstenedione; Animals; Dehydroep | 1977 |
A biphasic response of testicular 17beta-hydroxysteroid oxidoreductase associated with advancing age in heat-acclimatized mouse.
Topics: Acclimatization; Aging; Androstenediols; Androstenedione; Animals; Body Weight; Dehydroepiandrostero | 1977 |
Age-dependent and isoenzyme specific inhibition of heart glucose-6-phosphate dehydrogenase by dehydroepiandrosterone.
Topics: Aging; Animals; Dehydroepiandrosterone; Digitonin; Glucosephosphate Dehydrogenase; Heart; Isoenzymes | 1975 |
Enzymatic oxidation and reduction of C19-delta5-3beta-hydroxysteroids by hepatic microsomes. V. Testosterone as a neonatal determinant in rats of the 7- and 16alpha-hydroxylation and reduction of 3beta-hydroxyandrost-5-en-17-one (DHA).
Topics: Aging; Animals; Animals, Newborn; Dehydroepiandrosterone; Female; Hydroxysteroids; Kinetics; Liver; | 1975 |
Ovarian delta-5-3-beta-hydroxysteroid dehydrogenase in aging rats.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Animals; Corpus Luteum; Cricetinae; Dehydroepiandrosterone; Fem | 1975 |
The synthesis of testosterone and estradiol-17beta by the gonads of neonatal rats in vitro.
Topics: Aging; Animals; Animals, Newborn; Dehydroepiandrosterone; Estradiol; Female; Male; Ovary; Rats; Test | 1975 |
Puberty in girls: correlation of serum levels of gonadotropins, prolactin, androgens, estrogens, and progestins with physical changes.
Topics: Adolescent; Aging; Androgens; Androstenedione; Breast; Child; Dehydroepiandrosterone; Estradiol; Est | 1976 |
Enzymatic sulfation of steroids--VII. Hepatic cortisol sulfation and glucocorticoid sulfotransferases in old and young male rats.
Topics: Aging; Animals; Cytosol; Dehydroepiandrosterone; Glucocorticoids; Hydrocortisone; In Vitro Technique | 1978 |
Steroid hormone metabolism in skin and isolated sebaceous glands: preliminary observations on the effects of age.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gon | 1979 |
Human testicular secretion with increasing age.
Topics: Adult; Aged; Aging; Androstenediol; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone | 1979 |
Variations in serum androgens, estrogens, progestins, gonadotropins and prolactin levels in male rats from prepubertal to advanced age.
Topics: Aging; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Fo | 1979 |
Pattern of plasma dehydroepiandrosterone sulfate levels in humans from birth to adulthood: evidence for testicular production.
Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 1978 |
Plasma levels of gonadotropins, prolactin, thyroxine, and adrenal and gonadal steroids in obese prepubertal girls.
Topics: Adrenal Cortex Hormones; Aging; Child; Dehydroepiandrosterone; Estradiol; Female; Follicle Stimulati | 1978 |
Radioimmunoassay of 17beta-hydroxy-5alpha-androstan-3-one, 4-androstene-3,17-dione, dehydroepiandrosterone, 17-hydroxyprogesterone and progesterone and its application to the human male plasma.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Androstenedione; Castration; Circadian Rhythm; Cros | 1976 |
Inhibition of spontaneous testicular Leydig cell tumor development in F-344 rats by dehydroepiandrosterone.
Topics: Aging; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Diet; Hyperplasia; Leydig Cell Tumor; | 1992 |
Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Human | 1992 |
Natural regulators of T-cell lymphokine production in vivo.
Topics: Aging; Animals; Dehydroepiandrosterone; Glucocorticoids; Humans; Lymphokines; Mice; Mice, Inbred C3H | 1992 |
Neurosteroid metabolism. 7 alpha-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Animals; Brain; Dehydroepiandrosterone; Estrogens; Hydroxylatio | 1992 |
Delta 5-3 beta-hydroxysteroid acyl transferase activity in the rat brain.
Topics: Acyltransferases; Aging; Animals; Brain; Dehydroepiandrosterone; Fatty Acids; Hydrogen-Ion Concentra | 1992 |
Effects of age, smoking and vitamins on plasma DHEAS levels: a cross-sectional study in men.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepian | 1992 |
Studies to confirm the source of 11 beta-hydroxyandrostenedione.
Topics: Adult; Aging; Androstenedione; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrad | 1992 |
Dehydroepiandrosterone-induced reduction of Cryptosporidium parvum infections in aged Syrian golden hamsters.
Topics: Aging; Animals; Cricetinae; Cryptosporidiosis; Cryptosporidium parvum; Dehydroepiandrosterone; Disea | 1992 |
Endocrine and morphological maturation of the fetal and neonatal adrenal cortex in baboons.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aging; Animals; Animals, Newborn; Cesarean Section; Cir | 1991 |
Normative data for adrenal steroidogenesis in a healthy pediatric population: age- and sex-related changes after adrenocorticotropin stimulation.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenocortic | 1991 |
Decreased expression of cytochrome P450 17 alpha-hydroxylase mRNA in senescent bovine adrenal gland.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aging; Animals; Blotting, Southern; Cattle; Dehydroepia | 1991 |
Increased levels of DHEAS in serum of patients with X-linked ichthyosis.
Topics: Acetylation; Adult; Aging; Arylsulfatases; Cholesterol; Chromatography, Gas; Dehydroepiandrosterone; | 1991 |
Gonadotropin secretion during aging in postmenopausal women.
Topics: Aging; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrogens; Female; Follicl | 1991 |
Steroid glucuronides: human circulatory levels and formation by LNCaP cells.
Topics: Adolescent; Adult; Aging; Androstane-3,17-diol; Androstenedione; Child; Child, Preschool; Dehydroepi | 1991 |
Dehydroepiandrosterone sulphate in Alzheimer's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Dehydroepiandrosterone; Dehydr | 1990 |
Plasma dehydroepiandrosterone sulfate in nursing home men.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Brain Diseases; Chicago; Dehydroepiandro | 1990 |
Endocrine determinants of fertility: serum androgen concentrations during follow-up of adolescents into the third decade of life.
Topics: Adolescent; Adult; Aging; Androstenedione; Body Mass Index; Child; Dehydroepiandrosterone; Dehydroep | 1990 |
Changes in plasma DHEAS circadian rhythm in elderly men.
Topics: Adult; Aged; Aging; Body Temperature; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrostero | 1990 |
Age, steroids and bone mineral content.
Topics: Adult; Aged; Aging; Androgens; Androstenedione; Bone Density; Cross-Sectional Studies; Dehydroepiand | 1990 |
Effects of sport (football) on growth: auxological, anthropometric and hormonal aspects.
Topics: Adolescent; Aging; Anthropometry; Body Composition; Body Weight; Bone and Bones; Child; Dehydroepian | 1990 |
Marked attenuation of ultradian and circadian rhythms of dehydroepiandrosterone in postmenopausal women: evidence for a reduced 17,20-desmolase enzymatic activity.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aging; Aldehyde-Lyases; Circadian Rhythm; Cortic | 1990 |
Relationship between insulin, insulin-like growth factor I, and dehydroepiandrosterone sulfate concentrations during childhood, puberty, and adult life.
Topics: Adolescent; Adult; Age Factors; Aging; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepian | 1989 |
Plasma concentrations of testosterone, dihydrotestosterone, delta 4-androstenedione, dehydroepiandrosterone and oestradiol-17 beta in the crab-eating monkey (Macaca fascicularis) from birth to adulthood.
Topics: Aging; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Gonadal Ste | 1985 |
Testicular endocrine function in the ageing male.
Topics: Adult; Aged; Aging; Circadian Rhythm; Dehydroepiandrosterone; Diet; Dihydrotestosterone; Estradiol; | 1985 |
Plasma dehydroepiandrosterone, its sulfate, testosterone and FSH during puberty of African children in Gabon.
Topics: Adolescent; Adult; Aging; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fol | 1986 |
Inhibition of proteinuria development in aging Sprague-Dawley rats and C57BL/6 mice by long-term treatment with dehydroepiandrosterone.
Topics: Aging; Animals; Body Weight; Dehydroepiandrosterone; Eating; Male; Mice; Mice, Inbred C57BL; Protein | 1986 |
Observations on the role of GH/IGF-1 and sex hormone binding globulin (SHBG) in the pubertal development of growth hormone deficient (GHD) children.
Topics: Adolescent; Aging; Body Height; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandroster | 1986 |
A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.
Topics: Aged; Aging; Analysis of Variance; Cardiovascular Diseases; Coronary Disease; Dehydroepiandrosterone | 1986 |
Influence of neonatal androgenization on the testicular steroidogenesis in the adult rat.
Topics: 17-alpha-Hydroxyprogesterone; Aging; Androgens; Androstane-3,17-diol; Androstenedione; Animals; Anim | 1987 |
Declining adrenal androgens: an association with bone loss in aging women.
Topics: Adrenal Cortex; Aged; Aged, 80 and over; Aging; Androgens; Bone and Bones; Dehydroepiandrosterone; D | 1987 |
Dehydroepiandrosterone sulfate improves memory in aging mice.
Topics: Aging; Animals; Avoidance Learning; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Male; Me | 1988 |
Androgen parameters in hirsute women: correlations with body mass index and age.
Topics: Adolescent; Adult; Aging; Androgens; Body Weight; Dehydroepiandrosterone; Dehydroepiandrosterone Sul | 1988 |
Age-related changes in plasma dehydroepiandrosterone sulphate, cortisol, testosterone and free testosterone circadian rhythms in adult men.
Topics: Adult; Aged; Aged, 80 and over; Aging; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandroster | 1988 |
Treatment of central precocious puberty with an LHRH agonist (Buserelin): effect on growth and bone maturation after three years of treatment.
Topics: Aging; Body Height; Bone Development; Buserelin; Child; Dehydroepiandrosterone; Dehydroepiandrostero | 1987 |
Dehydroepiandrosterone sulphate and dehydroepiandrosterone in serum: differences related to age and sex.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Femal | 1988 |
Adrenocortical responsiveness to graded ACTH infusions in normal young and elderly human subjects.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Aldosteron | 1986 |
Responses of plasma adrenocorticotropin, cortisol, and dehydroepiandrosterone to ovine corticotropin-releasing hormone in healthy aging men.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Animals; Corticotropin-Releasing Hormone; Dehydroep | 1986 |
[Age-related changes in secretion of adrenocortical steroid hormones in normal healthy men].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; | 1986 |
Aging is without effect on the pituitary-adrenal axis in men.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Corticotropin-Releasing Hormone; Dehydroepiandroste | 1986 |
Kinetic analysis of adrenal 3 beta-hydroxysteroid dehydrogenase activity during human development.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Glands; Adult; Ag | 1985 |
[Endogenous steroids and otosclerosis].
Topics: Adult; Aging; Audiometry, Pure-Tone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Male; M | 1985 |
Puberty in the chimpanzee: somatomedin-C and its relationship to somatic growth and steroid hormone concentrations.
Topics: Aging; Animals; Dehydroepiandrosterone; Estradiol; Female; Gonadal Steroid Hormones; Hydrocortisone; | 1985 |
A genetic component to the variation of dehydroepiandrosterone sulfate.
Topics: Adolescent; Adult; Aged; Aging; Analysis of Variance; Child; Child, Preschool; Dehydroepiandrosteron | 1985 |
Concentrations of amino acids in plasma and muscle. Relationship to androgen metabolism during growth and development in the male.
Topics: 17-Ketosteroids; Adolescent; Adult; Aging; Amino Acids; Androsterone; Autoanalysis; Child; Dehydroep | 1966 |
[The elimination of 17-ketosteroids in aged subjects coming from different regions].
Topics: 17-Ketosteroids; Aged; Aging; Dehydroepiandrosterone; Humans; Italy; Middle Aged; Socioeconomic Fact | 1967 |
Plasma 17-ketosteroid levels during adolescence.
Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Aging; Child; Chromatography, Gas; Chromatography, Thin | 1969 |
[Geriatric study on the field of gyneco-obstetrics, with special reference to the significance and application of adrenal androgen in post-menopausal women].
Topics: Adrenal Glands; Aged; Aging; Androgens; Animals; Dehydroepiandrosterone; Female; Humans; Menopause; | 1969 |
Partial 3 -hydroxysteroid dehydrogenase (3 -HSD) deficiency in a family with congenital adrenal hyperplasia: evidence for increasing 3 -HSD activity with age.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Aging; Aldosterone; Androstanes; | 1971 |
[Use of testosterone derivatives in geriatrics].
Topics: 17-Ketosteroids; Aged; Aging; Androgens; Chromatography, Gas; Dehydroepiandrosterone; Humans; Liver; | 1970 |
Steroid biosynthesis in gonadal tissue from patients with testicular feminization.
Topics: Adult; Aging; Androgen-Insensitivity Syndrome; Carbon Isotopes; Chromatography; Dehydroepiandrostero | 1972 |
Enzymatic oxidation and reduction of C 19-delta 5-3 beta-hydroxysteroids by hepatic microsomes. II. Effect of age in rats on 16,17-oxido-reduction of 3 beta-hydroxyandrost-5-en-17-one (DHA).
Topics: Aging; Androstenes; Animals; Body Weight; Carbon Isotopes; Dehydroepiandrosterone; Female; Hydroxyst | 1973 |
Gonadotropins in female rats androgenized by various treatments: prolactin as an index to hypothalamic damage.
Topics: Aging; Androstenols; Animals; Animals, Newborn; Dehydroepiandrosterone; Estradiol; Estrus; Female; F | 1974 |
The excretion of steroids by pre-pubertal children during growth.
Topics: 17-Ketosteroids; Age Determination by Skeleton; Aging; Androsterone; Child; Dehydroepiandrosterone; | 1965 |
[Studies on urinary 17-ketogenic steroids (17-KGS) fractions in children, using sodium metaperiodate oxidation, with special reference to urinary 17-KGS, 17-KS and pregnanetriol in normal children].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Aging; Child; Child, Preschool; Chrom | 1966 |
[Adrenocortical hormones and aging process].
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; A | 1969 |
A longitudinal study of steroid excretion patterns in children during adolescent growth.
Topics: 17-Ketosteroids; Adolescent; Age Determination by Skeleton; Aging; Androstanes; Androsterone; Breast | 1970 |
Stimulating effect of crystalline cholesterol on spermiogenesis and oxidative activity in the senile rat testicle.
Topics: Aging; Androsterone; Animals; Cholesterol; Crystallization; Dehydroepiandrosterone; Dihydrolipoamide | 1973 |
Conversion of 17-alpha-hydroxypregnenolone to dehydroepiandrosterone by adrenal homogenates of immature and adult guinea pigs.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Aging; Animals; Animals, Newborn; Chr | 1967 |