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dehydroepiandrosterone and Age-Related Memory Disorders

dehydroepiandrosterone has been researched along with Age-Related Memory Disorders in 15 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"These results suggest that memory deficits in AD may be improved by sominone independently of reducing amyloid plaques and neuroinflammation."1.37Sominone improves memory impairments and increases axonal density in Alzheimer's disease model mice, 5XFAD. ( Joyashiki, E; Matsuya, Y; Tohda, C, 2011)
"Dehydroepiandrosterone (DHEA) has been implicated not only to prevent N-methyl-D-aspartate (NMDA)-induced neurotoxicity but also to enhance Ca(2+) influx through NMDA receptor (NMDAr)."1.35DHEA-neuroprotection and -neurotoxicity after transient cerebral ischemia in rats. ( Chen, L; Cui, S; Ge, Y; Li, Z; Sokabe, M; Zhang, Z; Zhou, R, 2009)
"Memory deficits were not explained by mood disturbances."1.30Pregnancy, the postpartum, and steroid hormones: effects on cognition and mood. ( Bluestein, BW; Buckwalter, DK; Buckwalter, JG; Chang, L; Goodwin, TM; McCleary, CA; Rankin, KP; Stanczyk, FZ, 1999)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's6 (40.00)29.6817
2010's6 (40.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Pitsikas, N2
Zoupa, E1
Gravanis, A2
Jiménez-Rubio, G1
Herrera-Pérez, JJ1
Hernández-Hernández, OT1
Martínez-Mota, L1
Yabuki, Y1
Shinoda, Y1
Izumi, H1
Ikuno, T2
Shioda, N1
Fukunaga, K2
Li, Z1
Cui, S1
Zhang, Z1
Zhou, R1
Ge, Y1
Sokabe, M1
Chen, L1
Joyashiki, E1
Matsuya, Y1
Tohda, C1
Moriguchi, S1
Yamamoto, Y1
Sorwell, KG1
Garten, J1
Renner, L1
Weiss, A1
Garyfallou, VT1
Kohama, SG1
Neuringer, M1
Urbanski, HF1
Harris, DS1
Wolkowitz, OM1
Reus, VI1
Kamei, H1
Noda, Y1
Nabeshima, T1
Yamada, K1
Avital, A1
Ram, E1
Maayan, R1
Weizman, A1
Richter-Levin, G1
Melchior, CL1
Ritzmann, RF1
Buckwalter, JG1
Stanczyk, FZ1
McCleary, CA1
Bluestein, BW1
Buckwalter, DK1
Rankin, KP1
Chang, L1
Goodwin, TM1
Racchi, M1
Govoni, S1
Solerte, SB1
Galli, CL1
Corsini, E1

Reviews

3 reviews available for dehydroepiandrosterone and Age-Related Memory Disorders

ArticleYear
Relationship between androgen deficiency and memory impairment in aging and Alzheimer’s disease.
    Actas espanolas de psiquiatria, 2017, Volume: 45, Issue:5

    Topics: Aged; Aging; Alzheimer Disease; Dehydroepiandrosterone; Humans; Memory Disorders; Testosterone

2017
[Effects of sigma receptor ligands on psychiatric disorders].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2003, Volume: 23, Issue:5

    Topics: Animals; Dehydroepiandrosterone; Disease Models, Animal; Humans; Learning Disabilities; Ligands; Mem

2003
Dehydroepiandrosterone and the relationship with aging and memory: a possible link with protein kinase C functional machinery.
    Brain research. Brain research reviews, 2001, Volume: 37, Issue:1-3

    Topics: Aging; Animals; Dehydroepiandrosterone; Enzyme Activation; Humans; Memory; Memory Disorders; Protein

2001

Other Studies

12 other studies available for dehydroepiandrosterone and Age-Related Memory Disorders

ArticleYear
The novel dehydroepiandrosterone derivative BNN27 counteracts the impairing effects of anesthetic ketamine on rats' non-spatial and spatial recognition memory.
    Behavioural brain research, 2022, 07-26, Volume: 430

    Topics: Anesthetics; Animals; Dehydroepiandrosterone; Ketamine; Memory Disorders; Rats; Rats, Wistar; Recogn

2022
Dehydroepiandrosterone administration improves memory deficits following transient brain ischemia through sigma-1 receptor stimulation.
    Brain research, 2015, Oct-05, Volume: 1622

    Topics: Adenosine Triphosphate; Animals; Anisoles; Brain Ischemia; CA1 Region, Hippocampal; Calcium-Calmodul

2015
The novel dehydroepiandrosterone (DHEA) derivative BNN27 counteracts delay-dependent and scopolamine-induced recognition memory deficits in rats.
    Neurobiology of learning and memory, 2017, Volume: 140

    Topics: Animals; Dehydroepiandrosterone; Exploratory Behavior; Male; Memory Disorders; Rats; Rats, Wistar; R

2017
DHEA-neuroprotection and -neurotoxicity after transient cerebral ischemia in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009, Volume: 29, Issue:2

    Topics: Animals; Cell Death; Dehydroepiandrosterone; Ischemic Attack, Transient; Male; Memory Disorders; Neu

2009
Can taking DHEA supplements improve my memory?
    The Johns Hopkins medical letter health after 50, 2008, Volume: 20, Issue:8

    Topics: Aged; Aged, 80 and over; Dehydroepiandrosterone; Humans; Memory; Memory Disorders; Middle Aged

2008
Sominone improves memory impairments and increases axonal density in Alzheimer's disease model mice, 5XFAD.
    The International journal of neuroscience, 2011, Volume: 121, Issue:4

    Topics: Alzheimer Disease; Animals; Axons; Cell Count; Cells, Cultured; Cerebral Cortex; Dehydroepiandroster

2011
Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice.
    Journal of neurochemistry, 2011, Volume: 117, Issue:5

    Topics: Animals; Anisoles; Avoidance Learning; Behavior, Animal; Blotting, Western; CA1 Region, Hippocampal;

2011
Hormone supplementation during aging: how much and when?
    Rejuvenation research, 2012, Volume: 15, Issue:2

    Topics: Aging; Androgens; Animals; Cognition; Cognition Disorders; Dehydroepiandrosterone; Hormones; Macaca

2012
Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2001, Volume: 2, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Dehydroepiandrosterone; Female; Humans; Hydrocort

2001
Effects of early-life stress on behavior and neurosteroid levels in the rat hypothalamus and entorhinal cortex.
    Brain research bulletin, 2006, Feb-15, Volume: 68, Issue:6

    Topics: Affective Symptoms; Age Factors; Animals; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiand

2006
Neurosteroids block the memory-impairing effects of ethanol in mice.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:1

    Topics: Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Ethanol; GABA-A Receptor Antagoni

1996
Pregnancy, the postpartum, and steroid hormones: effects on cognition and mood.
    Psychoneuroendocrinology, 1999, Volume: 24, Issue:1

    Topics: Adult; Affect; Awards and Prizes; Cognition; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydr

1999