dehydroepiandrosterone has been researched along with Adrenoleukodystrophy in 3 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Adrenoleukodystrophy: An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Assies, J | 2 |
| Haverkort, EB | 2 |
| Lieverse, R | 2 |
| Vreken, P | 2 |
| Gueugnon, F | 1 |
| Lambert, F | 1 |
| Gondcaille, C | 1 |
| Fourcade, S | 1 |
| Bellenger, J | 1 |
| Cadepond, F | 1 |
| El Etr, M | 1 |
| Savary, S | 1 |
| Bugaut, M | 1 |
2 trials available for dehydroepiandrosterone and Adrenoleukodystrophy
| Article | Year |
|---|---|
Effect of dehydroepiandrosterone supplementation on fatty acid and hormone levels in patients with X-linked adrenoleucodystrophy.
Topics: Adjuvants, Immunologic; Administration, Oral; Adrenoleukodystrophy; Adult; Androstenedione; Child; D | 2003 |
Effect of dehydroepiandrosterone (DHEA) supplementation on fatty acid and hormone levels in patients with X-linked adrenoleukodystrophy.
Topics: Adrenoleukodystrophy; Adult; Child; Dehydroepiandrosterone; Fatty Acids; Hormones; Humans; Male; Mid | 2003 |
1 other study available for dehydroepiandrosterone and Adrenoleukodystrophy
| Article | Year |
|---|---|
Dehydroepiandrosterone induction of the Abcd2 and Abcd3 genes encoding peroxisomal ABC transporters: implications for X-linked adrenoleukodystrophy.
Topics: Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D; ATP-Binding Cassette T | 2003 |