Compounds > dehydroepiandrosterone
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dehydroepiandrosterone and Adrenocortical Hyperfunction

dehydroepiandrosterone has been researched along with Adrenocortical Hyperfunction in 45 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Adrenocortical Hyperfunction: Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.

Research Excerpts

ExcerptRelevanceReference
"It has been hypothesized that the androgens testosterone and dehydroepiandrosterone (DHEA) may have opposing actions on insulin sensitivity."7.68Opposing actions of dehydroepiandrosterone and testosterone on insulin sensitivity. In vivo and in vitro studies of hyperandrogenic females. ( Buffington, CK; Givens, JR; Kitabchi, AE, 1991)
"It has been hypothesized that the androgens testosterone and dehydroepiandrosterone (DHEA) may have opposing actions on insulin sensitivity."3.68Opposing actions of dehydroepiandrosterone and testosterone on insulin sensitivity. In vivo and in vitro studies of hyperandrogenic females. ( Buffington, CK; Givens, JR; Kitabchi, AE, 1991)
"There months following surgery, liver metastases were documented associated with elevated levels of serum androgens."1.26Virilizing adrenal tumor in a child suppressed with dexamethasone for three years. Effect of o,p'-DDD on serum and urinary androgens. ( Korth-Schutz, S; Levine, LS; New, MI; Roth, JA; Saenger, P, 1977)
"Virilism is the major manifestation in children (83 percent of the cases), either isolated or associated with hypercortisolism and/or feminization."1.25[Corticosuprarenaloma in children]. ( Benaily, M; Job, JC; Schweisguth, O, 1975)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199035 (77.78)18.7374
1990's5 (11.11)18.2507
2000's4 (8.89)29.6817
2010's1 (2.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aicher, KM1
Cullen, JM1
Seiler, GS1
Lunn, KF1
Mathews, KG1
Gookin, JL1
Gambineri, A1
Forlani, G1
Munarini, A1
Tomassoni, F1
Cognigni, GE1
Ciampaglia, W1
Pagotto, U1
Walker, BR1
Pasquali, R1
GARDNER, LI1
MIGEON, CJ3
NATOLI, A1
MAGLIOCCA, R1
COHN, GL1
MULROW, PJ1
KOMOR, K1
GIUSTI, G1
TOCCAFONDI, R1
BORGHI, A1
ZURLI, A1
ANZALONE, M1
IACONO, G2
BRANCACCIO, A2
D ALESSANDRO, B2
DELUCA, R2
REPOLE, R2
Sieber-Ruckstuhl, NS1
Boretti, FS1
Wenger, M1
Maser-Gluth, C1
Reusch, CE1
Young, AH1
Kim, MH1
Chang, FE1
Abraham, GE1
Maroulis, GB1
Boyers, SP1
Buster, JE1
Magyar, DM1
Elsner, CW1
Lindholm, C1
Hirschberg, AL1
Carlström, K1
von Schoultz, B1
Hanson, JA1
Weber, A1
Reznek, RH1
Cotterill, AM1
Ross, RJ1
Harris, RJ1
Armstrong, P1
Savage, MO1
Frank, LA1
Schmeitzel, LP1
Oliver, JW1
Maclaren, NK1
Raiti, S1
Benaily, M1
Schweisguth, O1
Job, JC1
Korth-Schutz, S3
Levine, LS4
Roth, JA1
Saenger, P2
New, MI4
Reiter, EO1
Fuldauer, VG1
Root, AW1
Teller, WM1
Homoki, J1
Golden, MP1
Lippe, BM1
Kaplan, SA1
Lavin, N1
Slavin, J1
Sizonenko, PC1
Urban, MD1
Lee, PA1
Virdis, R1
Chow, DM1
Lorenzen, F1
Pang, S1
Gunczler, P1
Dupont, B1
Buffington, CK1
Givens, JR1
Kitabchi, AE1
Sidel'nikova, VM2
Orlova, VG2
Raisova, AT2
Agadzhanova, AA1
Radetti, G1
Cacciari, E1
Zachmann, M2
Kemeter, P1
de Moor, P1
Heyns, W1
Steeno, O1
Detter, F1
Kollmeier, W1
Klingmüller, V1
Göbel, P3
Horký, K1
Küchel, O1
Gregorvá, I1
Stárka, L1
Vaitukaitis, JL1
Melby, JC1
Cyran, J1
Gabos, P1
Loriaux, DL1
Ruder, HJ1
Lipsett, MB1
Macarulla, JM1
Gómez-Capilla, JA1
Osorio, C1
Yamaji, T1
Ibayashi, H1
Vollmin, JA1
Murset, G1
Curtius, HC1
Prader, A1
Cruikshank, DP1
Yannone, ME1
Chapler, FK1

Reviews

2 reviews available for dehydroepiandrosterone and Adrenocortical Hyperfunction

ArticleYear
Antiglucocoticoid treatments for depression.
    The Australian and New Zealand journal of psychiatry, 2006, Volume: 40, Issue:5

    Topics: Adrenocortical Hyperfunction; Dehydroepiandrosterone; Depressive Disorder, Major; Enzyme Inhibitors;

2006
Preadolescent and adolescent endocrinology: physiology and physiopathology. II. Hormonal changes during abnormal pubertal development.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:8

    Topics: Adolescent; Adrenocortical Hyperfunction; Androgen Antagonists; Child; Dehydroepiandrosterone; Estra

1978

Trials

3 trials available for dehydroepiandrosterone and Adrenocortical Hyperfunction

ArticleYear
Increased clearance of cortisol by 5beta-reductase in a subgroup of women with adrenal hyperandrogenism in polycystic ovary syndrome.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:3

    Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Androstenedione; Basal Metabolism; Cosyntropin; Deh

2009
Qualitative alterations in urinary 17-ketosteroid excretion during aminoglutethimide administration.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Aminoglutethimide; Androsterone; Aniline Compounds; A

1969
Plasma dehydroepiandrosterone sulfate in normal and pathological conditions.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction;

1969

Other Studies

40 other studies available for dehydroepiandrosterone and Adrenocortical Hyperfunction

ArticleYear
Investigation of adrenal and thyroid gland dysfunction in dogs with ultrasonographic diagnosis of gallbladder mucocele formation.
    PloS one, 2019, Volume: 14, Issue:2

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Animals; Autoantibodies; Case-Control Studies; Dehydro

2019
Urinary dehydroisoandrosterone in hyperadrenocorticism: influence of cortisone, hydrocortisone and ACTH.
    The Journal of clinical endocrinology and metabolism, 1952, Volume: 12, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone;

1952
[Urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with various endocrine diseases (Addison's disease, Cushing's disease, Cushing's syndrome, precocious puberty caused by congenital adrenal hyperplasia, acromegaly)].
    Il Progresso medico, 1955, Jun-30, Volume: 11, Issue:12

    Topics: 17-Ketosteroids; Acromegaly; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperf

1955
Androgen release and synthesis in vitro by human adult adrenal glands.
    The Journal of clinical investigation, 1963, Volume: 42

    Topics: Adrenal Cortex; Adrenal Glands; Adrenocortical Hyperfunction; Anatomy; Androgens; Dehydroepiandroste

1963
[ON THE TREATMENT OF ADRENAL CORTEX DISEASES].
    Magyar belorvosi archivum (1955), 1963, Volume: 16

    Topics: Addison Disease; Adrenal Cortex Diseases; Adrenal Insufficiency; Adrenocortical Hyperfunction; Adren

1963
[STUDIES OF SO-CALLED "SIMPLE" HIRSUTISM. VI. HORMONAL RESEARCH IN DYNAMIC CONDITIONS: REDUCTION WITH DEXAMETHASONE].
    Rassegna di neurologia vegetativa, 1963, Jun-30, Volume: 17

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Dehydroepiandros

1963
[CORTICOSTEROID CLEARANCE IN ADRENAL CORTEX DISEASES. INVESTIGATIONS WITH ACTH, CORTISONE, ALDOSTERONE AND HYDROCHLOROTHIAZIDE].
    Folia endocrinologica, 1964, Volume: 17

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Diseases; Adrenal Cortex Hormones; Adrena

1964
[STUDY OF ADRENAL CORTEX FUNCTION AFTER ADMINISTRATION OF HYDROCHLOROTHIAZIDE IN NORMAL SUBJECTS AND PATIENTS WITH ADRENAL GLAND DISEASES].
    Folia endocrinologica, 1964, Volume: 17

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adrenal Cortex; Adrenal Gland Diseases;

1964
Cortisol, aldosterone, cortisol precursor, androgen and endogenous ACTH concentrations in dogs with pituitary-dependant hyperadrenocorticism treated with trilostane.
    Domestic animal endocrinology, 2006, Volume: 31, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Adrenoc

2006
Chronic anovulation.
    Clinical obstetrics and gynecology, 1984, Volume: 27, Issue:4

    Topics: Adrenocortical Hyperfunction; Amenorrhea; Anorexia Nervosa; Anovulation; Breast Neoplasms; Chronic D

1984
Dexamethasone suppression test in the management of hyperandrogenized patients.
    Obstetrics and gynecology, 1981, Volume: 57, Issue:2

    Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Androgens; Dehydroepiandrosterone; Dexamethasone; D

1981
Altered adrenal steroid metabolism underlying hypercortisolism in female endurance athletes.
    Fertility and sterility, 1995, Volume: 63, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adult; Amenorrh

1995
Magnetic resonance imaging of adrenocortical adenomas in childhood: correlation with computed tomography and ultrasound.
    Pediatric radiology, 1996, Volume: 26, Issue:11

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hor

1996
Steroidogenic response of adrenal tissues after administration of ACTH to dogs with hypercortisolemia.
    Journal of the American Veterinary Medical Association, 2001, Jan-15, Volume: 218, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adrenocorticotr

2001
Gynecomastia with congenital virilizing adrenal hyperplasia (11-beta-hydroxylase deficiency).
    The Journal of pediatrics, 1975, Volume: 86, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Function Tests; Adrenal Hyperplasia, Cong

1975
[Corticosuprarenaloma in children].
    Archives francaises de pediatrie, 1975, Volume: 32, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal G

1975
Virilizing adrenal tumor in a child suppressed with dexamethasone for three years. Effect of o,p'-DDD on serum and urinary androgens.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:3

    Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Androgens; Child, Preschool;

1977
Secretion of the adrenal androgen, dehydroepiandrosterone sulfate, during normal infancy, childhood, and adolescence, in sick infants, and in children with endocrinologic abnormalities.
    The Journal of pediatrics, 1977, Volume: 90, Issue:5

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Function Tests; Adrenocortical Hyperfunction; Child; Chil

1977
Application of glass capillary gas chromatography to the study of urinary steroid excretion in normal children and in patients with various endocrinopathies.
    Padiatrie und Padologie. Supplementum, 1977, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; A

1977
Management of congenital adrenal hyperplasia using serum dehydroepiandrosterone sulfate and 17-hydroxyprogesterone concentrations.
    Pediatrics, 1978, Volume: 61, Issue:6

    Topics: 17-Ketosteroids; Adolescent; Adrenocortical Hyperfunction; Child; Child, Preschool; Cortisone; Dehyd

1978
Adult height and fertility in men with congenital virilizing adrenal hyperplasia.
    The New England journal of medicine, 1978, Dec-21, Volume: 299, Issue:25

    Topics: 17-Ketosteroids; Adolescent; Adrenocortical Hyperfunction; Adult; Body Height; Cell Count; Dehydroep

1978
Serum androgens as a continuing index of adequacy of treatment of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:3

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Androgens; Androsten

1978
Dehydroepiandrosterone sulfate (DS) levels, a rapid test for abnormal adrenal androgen secretion.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:6

    Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction;

1976
"Acquired" adrenal hyperplasia with 21-hydroxylase deficiency is not the same genetic disorders as congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:2

    Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenocor

1979
Opposing actions of dehydroepiandrosterone and testosterone on insulin sensitivity. In vivo and in vitro studies of hyperandrogenic females.
    Diabetes, 1991, Volume: 40, Issue:6

    Topics: Adrenocortical Hyperfunction; Blood Glucose; C-Peptide; Dehydroepiandrosterone; Female; Glucose Tole

1991
[Diagnosis of the causes and prevention of intrauterine fetal death in the second trimester of pregnancy in women with hyperandrogenism].
    Akusherstvo i ginekologiia, 1991, Issue:10

    Topics: Adrenal Cortex; Adrenocortical Hyperfunction; Adult; Dehydroepiandrosterone; Female; Fetal Death; Hu

1991
Isolated dehydroepiandrosterone sulphate hypersecretion: a case report.
    European journal of pediatrics, 1990, Volume: 149, Issue:11

    Topics: Adolescent; Adrenocortical Hyperfunction; Dehydroepiandrosterone; Dexamethasone; Diagnosis, Differen

1990
The usefulness of corticoids in stimulated cycles for in vitro fertilization.
    Journal of in vitro fertilization and embryo transfer : IVF, 1987, Volume: 4, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Clomiphene; Dehydroepiandrosterone; Dehydroep

1987
[Diagnosis and pathogenesis of abortion in women with adrenal hyperandrogenism].
    Akusherstvo i ginekologiia, 1987, Issue:10

    Topics: Abortion, Habitual; Abortion, Threatened; Adrenal Cortex Function Tests; Adrenocortical Hyperfunctio

1987
Clinical and biochemical features associated with extreme CBC-values; possible significance of these associations.
    Annales d'endocrinologie, 1968, Volume: 29

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Androsterone; Blood Protein

1968
[Pattern of urinary neutral 17-ketosteroids on the basis of thin layer chromatography].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1967, Volume: 5, Issue:4

    Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Androstan

1967
[Adrenal hirsutism (3-beta-hydroxysteroid dehydrogenase deficiency). Studies using chromatographic separation of the urinary 17-ketosteroid fraction. 3. On the differential diagnosis of adrenal hirsutism (M. Cushing, congenital adrenogenital syndrome)].
    Endokrinologie, 1968, Volume: 52, Issue:5

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre

1968
Menstrual disorders associated with adrenal dysfunction.
    Clinical obstetrics and gynecology, 1969, Volume: 12, Issue:3

    Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands;

1969
[Gas chromatography determination of urinary pregnanediol and -triol and its significance for the differentiation of adrenal hirsutism in women].
    Endokrinologie, 1969, Volume: 54, Issue:5

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adult; C

1969
Testicular feminization--hormonal evaluation. Report of a case.
    Obstetrics and gynecology, 1970, Volume: 36, Issue:5

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adult; Androgen-Insensitivit

1970
Plasma steroids in congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Androst

1974
[Quantitative analysis of steroids in urine by gas-liquid chromatography (author's transl)].
    Revista espanola de fisiologia, 1974, Volume: 30, Issue:2

    Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Androstenedione; Androstenols; Androsterone; Cholesta

1974
+On a procedure for determination of the adrenal cortex secreion rate of cortisol and dehydroepiandrosterone.
    Nuclear-Medizin, 1965

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Cushing Syndrome;

1965
Unusual type of congenital adrenal hyperplasia probably due to deficiency of 3-beta-hydroxysteroid dehydrogenase. Case report of a surviving girl and steroid studies.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:6

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenocorticotropic

1970
Arrhenoblastoma associated with adrenal androgenic hyperfunction.
    Obstetrics and gynecology, 1974, Volume: 43, Issue:4

    Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Adult; Amenorrhea; Androgens; Androstenedione; Contra

1974