Page last updated: 2024-11-07

dehydroepiandrosterone and Adrenal Cortex Cancer

dehydroepiandrosterone has been researched along with Adrenal Cortex Cancer in 64 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"Seven patients with Cushing's syndrome were treated with trilostane (WIN 24,540) 4 alpha,5-epoxy-17 beta-hydroxy-3-oxo-5 alpha-androstane-2 alpha-carbonitrile), an inhibitor of adrenal steroid biosynthesis."7.66Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis. ( Komanicky, P; Melby, JC; Spark, RF, 1978)
"A 58-year-old man had adrenocortical carcinoma in the right adrenal gland."5.30Changes in neoplastic cell features and sensitivity to mitotane during mitotane-induced remission in a patient with recurrent, metastatic adrenocortical carcinoma. ( Demura, H; Hirohara, D; Kanazawa, M; Nomura, K; Sawada, T; Seki, M; Takasaki, K, 1999)
"To develop a monoclonal antibody against dehydroepiandrosterone (DHEA) and miniaturize it, generating a single-chain antibody variable fragment (scFv) against DHEA as an adrenocortical carcinoma (ACC) marker."3.91Biomolecular engineering of antidehydroepiandrosterone antibodies: a new perspective in cancer diagnosis and treatment using single-chain antibody variable fragment. ( Alvarenga, LM; Becker-Finco, A; Billiald, P; de Figueiredo, BC; de Moraes, RN; Fogaça, RL; Moura, J; Noiray, M; Noronha, L; Silva, SK; Teixeira, KN; Woiski, TD, 2019)
"Reduced serum levels of dehydroepiandrosterone sulphate (DHEAS) have been shown in patients with Cushing's syndrome resulting from adrenocortical adenoma, in contrast with normal DHEAS levels in patients with Cushing's disease."3.69Reduced serum levels of dehydroepiandrosterone sulphate in adrenal incidentalomas: a marker of adrenocortical tumour. ( Blatto, A; Camanni, F; Carlini, M; Flecchia, D; Mazza, E; Messina, M; Olivieri, F; Serra, G, 1995)
"In order to elucidate the steroidogenesis of clinically nonfunctioning adrenocortical adenoma, we studied the aldosterone, cortisol (F) and dehydroepiandrosterone (DHEA) content and the expression of mRNA of cytochrome P450 for side chain cleavage (P450scc), 17 alpha-hydroxylase (P450c17)."3.68Disordered expression of adrenal steroidogenic P450 mRNAs in incidentally discovered nonfunctioning adrenal adenoma. ( Haji, M; Nawata, H; Ogo, A; Ohashi, M; Takayanagi, R; Yanase, T, 1992)
"We studied the contents of cortisol (F) and dehydroepiandrosterone (DHEA) and the expression of mRNA of cytochrome P-450 for side-chain cleavage (P-450scc), 17 alpha-hydroxylase (P-450c17), 21 alpha-hydroxylase (P-450c21) and 11 beta-hydroxylase (P-450c11) in adrenocortical adenomas from three patients with Cushing's syndrome."3.68Markedly increased expression of cytochrome P-450 17 alpha-hydroxylase (P-450c17) mRNA in adrenocortical adenomas from patients with Cushing's syndrome. ( Haji, M; Nawata, H; Ogo, A; Ohashi, M, 1991)
"We investigated the mechanism of dissociation of cortisol and dehydroepiandrosterone sulfate (DHEA-S) secretion by the adrenal glands after the removal of an adrenal gland containing an adrenocortical adenoma in a patient with Cushing's syndrome."3.67Mechanism of dissociation of cortisol and adrenal androgen secretion after removal of adrenocortical adenoma in patients with Cushing's syndrome. ( Higuchi, K; Ibayashi, H; Kato, K; Nawata, H; Takayanagi, R; Yanase, T, 1985)
"Slices of an adreno-cortical adenoma which had been obtained at operation from an 11-year-old girl with clinical signs of virilism were incubated with each of the following steroids: [1,2-3H]progesterone, [4-14C]pregnenolone, [1,2-3H]testosterone, [4-14C]androstenedione and [7-3H]dehydroepiandrosterone, respectively."3.66Studies on the metabolism of steroid hormones in a virilizing adrenal cortex adenoma. ( Bayer, JM; Breuer, H; Lisboa, BP; Nocke-Finck, L; Strassner, M, 1978)
"Seven patients with Cushing's syndrome were treated with trilostane (WIN 24,540) 4 alpha,5-epoxy-17 beta-hydroxy-3-oxo-5 alpha-androstane-2 alpha-carbonitrile), an inhibitor of adrenal steroid biosynthesis."3.66Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis. ( Komanicky, P; Melby, JC; Spark, RF, 1978)
"Clinical virilization with or without hypercortisolism was found in all eight children, who were 5 years old or younger."2.37Virilizing adrenocortical tumors in childhood: eight cases and a review of the literature. ( Green, OC; Lee, PD; Winter, RJ, 1985)
"Adrenocortical carcinoma is a heterogeneous and aggressive cancer that originates from steroidogenic cells within the adrenal cortex."1.72A Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma. ( Abate, A; Berruti, A; Bornstein, SR; Bothou, C; Cosentini, D; Hantel, C; Peitzsch, M; Penton, D; Sigala, S; Tiberio, GAM, 2022)
"Patients with adrenocortical adenomas (nonsecreting, n = 66; SH, n = 28) and 188 age- and sex-matched controls drawn from the general population participated in the study."1.42Steroid Profiling by LC-MS/MS in Nonsecreting and Subclinical Cortisol-Secreting Adrenocortical Adenomas. ( Casadio, E; Di Dalmazi, G; Fanelli, F; Garelli, S; Giampalma, E; Golfieri, R; Mezzullo, M; Mosconi, C; Pagotto, U; Pasquali, R; Rinaldi, E; Vicennati, V, 2015)
"In this young girl, virilization is due to concomitant ectopic and intra-adrenal adenomas of the adrenal cortex."1.39Virilization of a young girl caused by concomitant ectopic and intra-adrenal adenomas of the adrenal cortex. ( Bettendorf, M; Beuschlein, F; Choukair, D; Haufe, S; Holland-Cunz, S; Wudy, SA; Zwermann, O, 2013)
"The patients all presented with virilization and other hormone-related symptoms for an average duration of 6 mo."1.35Adrenocortical neoplasms in young children: age as a prognostic factor. ( Ahmed, AA, 2009)
"A 58-year-old man had adrenocortical carcinoma in the right adrenal gland."1.30Changes in neoplastic cell features and sensitivity to mitotane during mitotane-induced remission in a patient with recurrent, metastatic adrenocortical carcinoma. ( Demura, H; Hirohara, D; Kanazawa, M; Nomura, K; Sawada, T; Seki, M; Takasaki, K, 1999)
"Virilism is the major manifestation in children (83 percent of the cases), either isolated or associated with hypercortisolism and/or feminization."1.25[Corticosuprarenaloma in children]. ( Benaily, M; Job, JC; Schweisguth, O, 1975)
"Dehydroepiandrosterone was the main constituent of the androgen excess."1.25Virilizing adrenocortical adenoma responsive to gonadotrophin. ( Albrechtsen, R; Blichert-Toft, M; Hehlet, H; Vejlsted, H, 1975)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199032 (50.00)18.7374
1990's18 (28.13)18.2507
2000's5 (7.81)29.6817
2010's7 (10.94)24.3611
2020's2 (3.13)2.80

Authors

AuthorsStudies
Sigala, S1
Bothou, C1
Penton, D1
Abate, A1
Peitzsch, M1
Cosentini, D1
Tiberio, GAM1
Bornstein, SR2
Berruti, A1
Hantel, C1
Zhu, H1
Wu, L1
Su, T1
Jiang, L1
Zhou, W1
Jiang, Y1
Zhang, C1
Zhong, X1
Wang, W1
Fogaça, RL1
Alvarenga, LM1
Woiski, TD1
Becker-Finco, A1
Teixeira, KN1
Silva, SK1
de Moraes, RN1
Noronha, L1
Noiray, M1
de Figueiredo, BC1
Billiald, P1
Moura, J1
Choukair, D1
Beuschlein, F1
Zwermann, O1
Wudy, SA1
Haufe, S1
Holland-Cunz, S1
Bettendorf, M1
Monno, S1
Tachikawa, T1
Maekawa, T1
Sasano, H4
Turcu, AF1
Auchus, RJ1
Di Dalmazi, G1
Fanelli, F1
Mezzullo, M1
Casadio, E1
Rinaldi, E1
Garelli, S1
Giampalma, E1
Mosconi, C1
Golfieri, R1
Vicennati, V1
Pagotto, U1
Pasquali, R1
Velikanova, LI1
Shafigullina, ZR1
Lisitsin, AA1
Vorokhobina, NV1
Grigoryan, K1
Kukhianidze, EA1
Strelnikova, EG1
Krivokhizhina, NS1
Krasnov, LM1
Fedorov, EA1
Sablin, IV1
Moskvin, AL1
Bessonova, EA1
Ahmed, AA1
Kouyama, R1
Hiraishi, K1
Sugiyama, T1
Izumiyama, H1
Yoshimoto, T2
Akashi, T1
Kihara, K1
Homma, K2
Shibata, H2
Hirata, Y2
GARDNER, LI2
MIGEON, CJ2
BAULIEU, EE1
WALLACE, EZ1
LIEBERMAN, S1
Fukai, N1
Hirono, Y1
Doi, M1
Ohtsuka, Y1
Mann, MW1
Ellis, SS1
Mallory, SB1
Vierhapper, H1
Nowotny, P1
Krisch, K1
Kletter, K1
Waldhäusl, W1
Roger, M1
Chaussain, JL1
Evain, D1
Toublanc, JE1
Canlorbe, P1
Scholler, R1
Watanobe, H2
Kannari, K2
Murabayashi, S1
Kimura, K2
Takebe, K2
Ojima, M1
Suzuki, K1
Murakami, Y1
Sasaki, M1
Suzuki, T1
Kitamura, N1
Tomoi, M1
Yorifuji, H1
Koshimura, K1
Kato, Y1
Flecchia, D1
Mazza, E1
Carlini, M1
Blatto, A1
Olivieri, F1
Serra, G1
Camanni, F1
Messina, M1
Rainey, WE3
Bird, IM3
Mason, JI3
Sawetawan, C1
Hanley, NA1
McCarthy, JL1
McGee, EA1
Wester, R1
Bencsik, Z1
Szabolcs, I1
Kovács, Z1
Ferencz, A1
Vörös, A1
Kaszás, I1
Bor, K1
Gönczi, J1
Góth, M1
Kovács, L1
Dohán, O1
Szilágyi, G1
Hanson, JA1
Weber, A2
Reznek, RH1
Cotterill, AM2
Ross, RJ1
Harris, RJ1
Armstrong, P1
Savage, MO2
Street, ME1
Camacho-Hübner, C1
Perry, LA1
Brain, CE1
Sandrini, R1
Ribeiro, RC1
DeLacerda, L1
Haidan, A1
Hilbers, U1
Ehrhart-Bornstein, M1
Imai, T1
Tobinaga, J1
Morita-Matsuyama, T1
Kikumori, T1
Seo, H1
Funahashi, H1
Kołomecki, K1
Stepień, H1
Narebski, JM1
Seki, M1
Nomura, K1
Hirohara, D1
Kanazawa, M1
Sawada, T1
Takasaki, K1
Demura, H1
Tsagarakis, S1
Tsigos, C1
Vassiliou, V1
Tsiotra, P1
Pratsinis, H1
Kletsas, D1
Trivizas, P1
Nikou, A1
Mavromatis, T1
Sotsiou, F1
Raptis, S1
Thalassinos, N1
Rosenfeld, RS1
Rosenberg, BJ1
Fukushima, DK2
Hellman, L3
Hayashida, K1
Inui, A1
Kinugasa, A1
Tomizawa, M1
Sawada, J1
Benaily, M1
Schweisguth, O1
Job, JC1
Boyar, RM2
Nogeire, C2
Fukushima, D1
Fishman, J1
Aiba, M2
Kameya, T1
Suzuki, H2
Nakamura, H1
Mizuno, Y1
Kanno, T1
Blichert-Toft, M1
Vejlsted, H1
Hehlet, H1
Albrechtsen, R1
Metcalf, MG1
Lisboa, BP1
Strassner, M1
Nocke-Finck, L1
Breuer, H1
Bayer, JM1
Schteingart, DE1
Woodbury, MC1
Tsao, HS1
McKenzie, AK1
Pugeat, M1
Saez, JM1
Riou, JP1
Merchak, A1
Tourniaire, J1
Komanicky, P1
Spark, RF1
Melby, JC1
Delemer, B1
Gibold, C1
Caron, J1
Liehn, JC1
Delisle, MJ1
Skogseid, B1
Larsson, C1
Lindgren, PG1
Kvanta, E1
Rastad, J1
Theodorsson, E1
Wide, L1
Wilander, E1
Oberg, K1
Ruutiainen, K1
Satokari, K1
Anttila, L1
Erkkola, R1
Ogo, A2
Haji, M2
Ohashi, M2
Takayanagi, R2
Yanase, T2
Nawata, H3
Gröndal, S1
Eriksson, B1
Hagenäs, L1
Werner, S1
Curstedt, T1
Takiuchi, H1
Oka, T1
Namiki, M1
Ichikawa, Y1
Sonoda, T1
Koga, M1
Sato, B1
Onishi, S1
Nakamura, T1
Matsushita, H1
Itoh, S1
Tanaka, K1
Horiuchi, T1
Kumagae, M1
Watabe, T1
Kanbegawa, A1
Shimizu, N1
Hintze, G1
Köbberling, J1
Becker, HD1
Helmchen, U1
Hoffmann, W1
Schuster, R1
Higuchi, K1
Kato, K1
Ibayashi, H1
Mattox, JH1
Phelan, S1
Kamiya, T1
Yasui, T1
Yokomori, H1
Nakamoto, H1
Maruyama, T1
Suzuki, O1
Ookawa, H1
Kiryu, Y1
Yasumura, K1
Kakumoto, Y1
Zhu, XP1
O'Leary, TJ1
Ooi, TC1
Miller, JD1
Branchaud, CL1
Kalra, J1
Davies, RP1
Lam, AH1
Iri, H1
Kageyama, K1
Kawai, T1
Abe, O1
Murai, M1
Tazaki, H1
Saruta, T1
Lee, PD1
Winter, RJ1
Green, OC1
Gleispach, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Potassium Supplementation in Healthy Men - Interactions With the Renin-angiotensin-aldosterone System and the Sympathetic Nervous System[NCT02380157]Phase 425 participants (Actual)Interventional2015-03-31Completed
Structured Evaluation of adRENal Tumors Discovered Incidentally - Prospectively Investigating the Testing Yield[NCT02324647]1,000 participants (Anticipated)Observational [Patient Registry]2015-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for dehydroepiandrosterone and Adrenal Cortex Cancer

ArticleYear
Adrenal steroidogenesis and congenital adrenal hyperplasia.
    Endocrinology and metabolism clinics of North America, 2015, Volume: 44, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; Aldosterone; Andr

2015
[Common and uncommon forms of female sexual precocity and their biological diagnosis].
    Annales de pediatrie, 1984, Volume: 31, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital;

1984
The NCI-H295 cell line: a pluripotent model for human adrenocortical studies.
    Molecular and cellular endocrinology, 1994, Volume: 100, Issue:1-2

    Topics: 3-Hydroxysteroid Dehydrogenases; Adenocarcinoma; Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Co

1994
[2 surgically treated cases of adrenocortical carcinoma producing steroid hormones without endocrinological symptoms--case report and a review of cases in the Japanese literature].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:1

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adult; Carcinoma; Dehydroepiandr

1988
Virilizing adrenocortical tumors in childhood: eight cases and a review of the literature.
    Pediatrics, 1985, Volume: 76, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adenoma; Adrenal Cortex Neoplasms; Child

1985

Other Studies

59 other studies available for dehydroepiandrosterone and Adrenal Cortex Cancer

ArticleYear
A Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma.
    Cells, 2022, 04-24, Volume: 11, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldoste

2022
Association between contralateral adrenal and hypothalamus-pituitary-adrenal axis in benign adrenocortical tumors.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Dehydroepiandrosteron

2023
Biomolecular engineering of antidehydroepiandrosterone antibodies: a new perspective in cancer diagnosis and treatment using single-chain antibody variable fragment.
    Nanomedicine (London, England), 2019, Volume: 14, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Animals; Biomarkers, Tumor; Dehydroepiandrostero

2019
Virilization of a young girl caused by concomitant ectopic and intra-adrenal adenomas of the adrenal cortex.
    Hormone research in paediatrics, 2013, Volume: 79, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Androsterone; Antineo

2013
A case of Cushing's syndrome due to bilateral cortisol-secreting adenomas with unilateral DHEAS oversecretion.
    Endocrine journal, 2015, Volume: 62, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Cushing Syndrome; Dehydroepi

2015
Steroid Profiling by LC-MS/MS in Nonsecreting and Subclinical Cortisol-Secreting Adrenocortical Adenomas.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:9

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Androstenedion

2015
Different Types of Urinary Steroid Profiling Obtained by High-Performance Liquid Chromatography and Gas Chromatography-Mass Spectrometry in Patients with Adrenocortical Carcinoma.
    Hormones & cancer, 2016, Volume: 7, Issue:5-6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocortical Carcinoma; Adult; Chromatography, H

2016
Adrenocortical neoplasms in young children: age as a prognostic factor.
    Annals of clinical and laboratory science, 2009,Summer, Volume: 39, Issue:3

    Topics: Adrenal Cortex Neoplasms; Age Factors; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Inf

2009
Clinicopathological features, biochemical and molecular markers in 5 patients with adrenocortical carcinoma.
    Endocrine journal, 2011, Volume: 58, Issue:7

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Neoplasms; Adrenocortical

2011
Urinary dehydroisoandrosterone in hyperadrenocorticism: influence of cortisone, hydrocortisone and ACTH.
    The Journal of clinical endocrinology and metabolism, 1952, Volume: 12, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone;

1952
[Ester-sulfates of steroid hormones. Isolation of the ester-sulfate of 5-androstene-3 beta-ol-17-one (dehydroepiandrosterone) in an adrenocortical tumor. Absence of the free steroid].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1960, Oct-03, Volume: 251

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Androgens; Androstenes; Cyclosporins; Dehydroepiandrostero

1960
Biosynthesis of dehydroisoandrosterone sulfate by human adrenocortical tissue.
    The Journal of clinical endocrinology and metabolism, 1963, Volume: 23

    Topics: Adrenal Cortex Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans

1963
[Diagnosis of virilizing tumors of the adrenal cortex: effect of cortisone on urinary steroids and application of a calorimetric method for determination of dehydroisoandrosterone].
    Helvetica paediatrica acta, 1951, Volume: 6, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Cortisone; Dehydroepiandrosterone; Female; Humans; Steroid

1951
A case of estrogen-secreting adrenocortical carcinoma with subclinical Cushing's syndrome.
    Endocrine journal, 2006, Volume: 53, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Cushing Syndrome; Dehydroepiandrosterone;

2006
Infantile acne as the initial sign of an adrenocortical tumor.
    Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:2 Suppl

    Topics: Acne Vulgaris; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Dehydroepiandrosterone; Hair; Human

2007
[Androgen-producing adrenal adenoma in an 18 year-old woman: diagnosis by gas-chromatographic steroid analysis, histology and postoperative course].
    Wiener klinische Wochenschrift, 1982, Dec-24, Volume: 94, Issue:24

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Androgens; Androstenediols; Androsterone; Chromatogra

1982
[A case of adrenocortical carcinoma with Cushing's syndrome presenting unusual urinary 17-ketosteroid fractionation].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:14

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Neoplasms; Adult; Androsterone; Cushing Syndrome; Dehydroe

1984
Young female patient with testosterone-producing adrenocortical adenoma also showing signs of subclinical Cushing's syndrome.
    Endocrine journal, 1995, Volume: 42, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Cortex Neoplasms; Adult; Circadian Rhyt

1995
Reduced serum levels of dehydroepiandrosterone sulphate in adrenal incidentalomas: a marker of adrenocortical tumour.
    Clinical endocrinology, 1995, Volume: 42, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult;

1995
Regulation of human adrenal carcinoma cell (NCI-H295) production of C19 steroids.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Androstenedione; Buc

1993
Adrenal androgen biosynthesis with special attention to P450c17.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 774

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Neoplasms; Aldehyde-Lyases; Aldosterone; Base Sequen

1995
Low dehydroepiandrosterone sulfate (DHEA-S) level is not a good predictor of hormonal activity in nonselected patients with incidentally detected adrenal tumors.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and ov

1996
Magnetic resonance imaging of adrenocortical adenomas in childhood: correlation with computed tomography and ultrasound.
    Pediatric radiology, 1996, Volume: 26, Issue:11

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hor

1996
Girls with virilisation in childhood: a diagnostic protocol for investigation.
    Journal of clinical pathology, 1997, Volume: 50, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Androgens; Child; Child, Preschool; Clini

1997
Childhood adrenocortical tumors.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:7

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Age Factors; Child; Child, Preschool; Cushing

1997
Human adrenocortical NCI-H295 cells express VIP receptors. Steroidogenic effect of vasoactive intestinal peptide (VIP).
    Peptides, 1998, Volume: 19, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Aldosterone; Dehydroepiandrostero

1998
Virilizing adrenocortical adenoma: in vitro steroidogenesis, immunohistochemical studies of steroidogenic enzymes, and gene expression of corticotropin receptor.
    Surgery, 1999, Volume: 125, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Ad

1999
Vascular endothelial growth factor and basic fibroblast growth factor evaluation in blood serum of patients with hormonally active and inactive adrenal gland tumours.
    Cytobios, 2000, Volume: 101, Issue:396

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Medulla; Adrenalectomy; Adult; Aged; Carc

2000
Changes in neoplastic cell features and sensitivity to mitotane during mitotane-induced remission in a patient with recurrent, metastatic adrenocortical carcinoma.
    Endocrine-related cancer, 1999, Volume: 6, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Antineoplastic Agents, Hormonal; Dehydroepiandro

1999
Food-dependent androgen and cortisol secretion by a gastric inhibitory polypeptide-receptor expressive adrenocortical adenoma leading to hirsutism and subclinical Cushing's syndrome: in vivo and in vitro studies.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult;

2001
24-Hour secretory pattern of dehydroisoandrosterone and dehydroisoandrosterone sulfate.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Circadian Rhythm; Dehydroepiandrosterone; Female; Hu

1975
[Adrenal cortex adenoma with unilateral obesity--its endocrine function and diagnosis].
    Horumon to rinsho. Clinical endocrinology, 1975, Volume: 23, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Child, Preschool; Cushing Syndrome; Dehy

1975
[Corticosuprarenaloma in children].
    Archives francaises de pediatrie, 1975, Volume: 32, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal G

1975
Studies of the diurnal pattern of plasma corticosteroids and gonadotropins in two cases of feminizing adrenal carcinoma: measurements of estrogen and corticosteroid production.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Androgens; Circad

1977
Virilizing adrenal cortical carcinoma.
    Cancer, 1977, Volume: 40, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Carcinoma; Circadian Rhythm; Dehydroepiand

1977
Enzyme histochemical and electron microscopic study of a virilizing adrenocortical adenoma.
    Acta pathologica japonica, 1978, Volume: 28, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Adenoma; Adrenal Cortex Neoplasms; Adult; Dehydroepiandrosterone; E

1978
Virilizing adrenocortical adenoma responsive to gonadotrophin.
    Acta endocrinologica, 1975, Volume: 78, Issue:1

    Topics: 11-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplas

1975
Dehydroepiandrosterone--sulphate in urine.
    Clinical biochemistry, 1978, Volume: 11, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotropic

1978
Studies on the metabolism of steroid hormones in a virilizing adrenal cortex adenoma.
    Endokrinologie, 1978, Volume: 72, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Androstenedione; Child; Chromatography, Gas; Dehydroepiandrostero

1978
Virilizing syndrome associated with an adrenal cortical adenoma secreting predominantly testosterone.
    The American journal of medicine, 1979, Volume: 67, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Androstenedione; Dehydroepian

1979
[A feminizing adrenal carcinoma in man: in vivo and in vitro study (author's transl)].
    Annales d'endocrinologie, 1979, Volume: 40, Issue:6

    Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Androstenedione; Carc

1979
Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:5

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adu

1978
[Role of adrenocortical scintigraphy in the exploration of incidentally discovered tumors].
    Annales d'endocrinologie, 1992, Volume: 53, Issue:4

    Topics: Adenoma; Adosterol; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Ag

1992
Clinical and genetic features of adrenocortical lesions in multiple endocrine neoplasia type 1.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 75, Issue:1

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Chr

1992
Adrenal- and ovarian-vein steroids and LH response to GnRH in two patients with virilizing adrenocortical adenoma studied by selective catheterizations.
    Hormone research, 1992, Volume: 37, Issue:1-2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Androgens; Androsterone; Catheterization;

1992
Disordered expression of adrenal steroidogenic P450 mRNAs in incidentally discovered nonfunctioning adrenal adenoma.
    Endocrinologia japonica, 1992, Volume: 39, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aged; Aldosterone; Blotting, Northern; Cytochrome P-450 Enzyme Sy

1992
Markedly increased expression of cytochrome P-450 17 alpha-hydroxylase (P-450c17) mRNA in adrenocortical adenomas from patients with Cushing's syndrome.
    Molecular and cellular endocrinology, 1991, Volume: 80, Issue:1-3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Blotting, Northern; Cushing Syndrome; Dehydroepiandrostero

1991
Steroid profile in urine: a useful tool in the diagnosis and follow up of adrenocortical carcinoma.
    Acta endocrinologica, 1990, Volume: 122, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adult; Aged; Biomarkers, Tumor; Carcinoma; Child; Child, Preschool; Cortod

1990
A case of virilizing adrenocortical carcinoma.
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; A

1987
Dehydroepiandrosterone sulfate (DHEA-S) and 3', 5'-cyclic adenosine monophosphate (cAMP) production in a cultured human adrenocortical carcinoma cell line (SW-13).
    Endocrinologia japonica, 1988, Volume: 35, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; alpha-MSH; Angiotensin II; Calcimycin; Carcin

1988
Bilateral virilizing adrenal tumor in a 17 year old woman.
    Journal of endocrinological investigation, 1985, Volume: 8, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Androstenedione; Dehydroepiandrosterone; Dehydroepian

1985
Mechanism of dissociation of cortisol and adrenal androgen secretion after removal of adrenocortical adenoma in patients with Cushing's syndrome.
    Endocrinologia japonica, 1985, Volume: 32, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Atrophy; Cells, Cultured;

1985
The evaluation of adult females with testosterone producing neoplasms of the adrenal cortex.
    Surgery, gynecology & obstetrics, 1987, Volume: 164, Issue:2

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate;

1987
[Adrenal cortical carcinoma (ACC)--report of 10 cases].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1988, Volume: 10, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adult; Aged; Carcinoma; Dehydr

1988
Virilization of two siblings by maternal androgen-secreting adrenal adenoma.
    The Journal of pediatrics, 1986, Volume: 109, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone

1986
Adrenocortical neoplasm in children. Ultrasound appearance.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 1987, Volume: 6, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Male; U

1987
Numerous mast cells in an 11-deoxycorticosterone-producing adrenocortical tumor. Histologic evaluation of benignancy and comparison with mast cell distribution in adrenal glands and neoplastic counterparts of 67 surgical specimens.
    Archives of pathology & laboratory medicine, 1985, Volume: 109, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Carcinoma, Renal Cell; Dehydroepiandro

1985
Adrenocortical carcinoma with Cushing's syndrome presenting unusual urinary 17-ketosteroid fractionation.
    Journal of endocrinological investigation, 1985, Volume: 8, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adult; Androstenedione; And

1985
[The urinary excretion of 17-oxosteroids, pregnanes and testosterone in relation to age and sex (author's transl)].
    Wiener klinische Wochenschrift. Supplementum, 1974, Volume: 23

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Adult; Age Factors; Aged; Androsterone; Chemi

1974