dehydroepiandrosterone has been researched along with Adjuvant Arthritis in 9 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The endogenous steroid dehydroepiandrosterone (DHEA) has been reported to play a role in rheumatoid arthritis (RA)." | 3.72 | Severity of murine collagen-induced arthritis correlates with increased CYP7B activity: enhancement of dehydroepiandrosterone metabolism by interleukin-1beta. ( Bagchus, WM; Boots, AM; Dulos, J; Kaptein, A; Verbraak, E, 2004) |
| "Dehydroepiandrosterone (DHEA) has attracted much interest because of its many antiaging, metabolic and immune-modulating effects in rodents." | 1.34 | A new orally bioavailable synthetic androstene inhibits collagen-induced arthritis in the mouse: androstene hormones as regulators of regulatory T cells. ( Auci, D; Frincke, J; Huang, Y; Kaler, L; Offner, H; Reading, C; Subramanian, S, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Auci, DL | 3 |
| Reading, CL | 3 |
| Frincke, JM | 1 |
| Mangano, K | 1 |
| Destiche, D | 1 |
| White, SK | 1 |
| Huang, Y | 2 |
| Boyle, D | 1 |
| Frincke, J | 2 |
| Nicoletti, F | 1 |
| Kobayashi, Y | 1 |
| Tagawa, N | 1 |
| Muraoka, K | 1 |
| Okamoto, Y | 1 |
| Nishida, M | 1 |
| Offner, H | 2 |
| Zamora, A | 1 |
| Subramanian, S | 2 |
| Polanczyk, M | 1 |
| Krogstad, A | 1 |
| Morgan, EE | 1 |
| Röntzsch, A | 1 |
| Thoss, K | 1 |
| Petrow, PK | 1 |
| Henzgen, S | 1 |
| Bräuer, R | 1 |
| Dulos, J | 1 |
| Verbraak, E | 1 |
| Bagchus, WM | 1 |
| Boots, AM | 1 |
| Kaptein, A | 1 |
| Auci, D | 1 |
| Kaler, L | 1 |
| Reading, C | 1 |
| Williams, PJ | 1 |
| Jones, RH | 1 |
| Rademacher, TW | 1 |
| Schwartz, AG | 1 |
| Pashko, LL | 1 |
1 review available for dehydroepiandrosterone and Adjuvant Arthritis
| Article | Year |
|---|---|
7-Hydroxy androstene steroids and a novel synthetic analogue with reduced side effects as a potential agent to treat autoimmune diseases.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Clinical Trials as Topic; Colitis; Dehyd | 2009 |
8 other studies available for dehydroepiandrosterone and Adjuvant Arthritis
| Article | Year |
|---|---|
Oral treatment with HE3286 ameliorates disease in rodent models of rheumatoid arthritis.
Topics: Administration, Oral; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Body Weight; Dehydroe | 2010 |
Participation of endogenous dehydroepiandrosterone and its sulfate in the pathology of collagen-induced arthritis in mice.
Topics: Animals; Arthritis, Experimental; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Interleuki | 2003 |
A synthetic androstene analogue inhibits collagen-induced arthritis in the mouse.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Cell Division; Cytokines; Dehydroepiandr | 2004 |
Amelioration of murine antigen-induced arthritis by dehydroepiandrosterone (DHEA).
Topics: Adjuvants, Immunologic; Androstenediol; Animals; Antibodies, Anti-Idiotypic; Arthritis, Experimental | 2004 |
Severity of murine collagen-induced arthritis correlates with increased CYP7B activity: enhancement of dehydroepiandrosterone metabolism by interleukin-1beta.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Blotting, Western; Chromatography, High Pre | 2004 |
A new orally bioavailable synthetic androstene inhibits collagen-induced arthritis in the mouse: androstene hormones as regulators of regulatory T cells.
Topics: Administration, Oral; Androstenes; Animals; Arthritis, Experimental; Cattle; Cell Proliferation; Cel | 2007 |
Reduction in the incidence and severity of collagen-induced arthritis in DBA/1 mice, using exogenous dehydroepiandrosterone.
Topics: Animals; Arthritis, Experimental; Autoantibodies; Collagen; Dehydroepiandrosterone; Dose-Response Re | 1997 |
Inhibition of adjuvant-induced arthritis by 16 alpha-fluoro-5-androsten-17-one.
Topics: Animals; Antineoplastic Agents; Arthritis, Experimental; Dehydroepiandrosterone; Female; Rats; Rats, | 2002 |