dehydroepiandrosterone has been researched along with Acquired Immunodeficiency Syndrome in 14 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the study was to relate plasma dehydroepiandrosterone sulfate (DHEA-S) concentrations to the progression of HIV infection in individual HIV-infected men with hemophilia and to obtain information on the cause of DH EA-S alterations." | 3.69 | Longitudinal study of adrenal steroids in a cohort of HIV-infected patients with hemophilia. ( Chatterton, RT; Green, D; Grossman, A; Harris, S; Hechter, O, 1996) |
| " DHEA dosing was flexible (100-400 mg/day)." | 2.72 | Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDS. ( Ferrando, SJ; McElhiney, MC; McGrath, PJ; Rabkin, JG; Rabkin, R, 2006) |
| "Dehydroepiandrosterone (DHEA) is a naturally occurring adrenal steroid reported to have immunomodulatory and antiviral activity in cellular and animal models as well as modest in vitro antiretroviral activity against human immunodeficiency virus (HIV)." | 2.67 | An open-label dose-escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease. ( Dyner, TS; Galmarini, M; Geaga, J; Golub, A; Jacobson, MA; Lang, W; Masterson, J; Stites, D; Winger, E, 1993) |
| "The use of DHEA for the treatment of AIDS shows some promise, although controlled trials have not been performed to evaluate its efficacy." | 1.30 | The role of dehydroepiandrosterone in AIDS. ( Abate, MA; Centurelli, MA, 1997) |
| "DHEA's background and use as an AIDS treatment are reviewed." | 1.29 | DHEA and AIDS. ( James, JS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, L | 1 |
| Liu, S | 1 |
| Wu, Y | 1 |
| Yang, J | 1 |
| Qiao, S | 1 |
| Zhou, Y | 1 |
| Deng, H | 1 |
| Li, X | 1 |
| Shen, Z | 1 |
| Chen, CC | 1 |
| Parker, CR | 1 |
| Rabkin, JG | 1 |
| McElhiney, MC | 1 |
| Rabkin, R | 1 |
| McGrath, PJ | 1 |
| Ferrando, SJ | 1 |
| Laudat, A | 1 |
| Blum, L | 1 |
| Guéchot, J | 1 |
| Picard, O | 1 |
| Cabane, J | 1 |
| Imbert, JC | 1 |
| Giboudeau, J | 1 |
| Dyner, TS | 1 |
| Lang, W | 1 |
| Geaga, J | 1 |
| Golub, A | 1 |
| Stites, D | 1 |
| Winger, E | 1 |
| Galmarini, M | 1 |
| Masterson, J | 1 |
| Jacobson, MA | 1 |
| Wisniewski, TL | 1 |
| Mendel, E | 1 |
| Morse, EV | 1 |
| Hilton, CW | 1 |
| Svec, F | 1 |
| Brind, J | 1 |
| Chatterton, RT | 1 |
| Green, D | 1 |
| Harris, S | 1 |
| Grossman, A | 1 |
| Hechter, O | 1 |
| Centurelli, MA | 1 |
| Abate, MA | 1 |
| Christeff, N | 2 |
| Gharakhanian, S | 1 |
| Thobie, N | 1 |
| Wirbel, E | 1 |
| Dalle, MT | 1 |
| Costagliola, D | 1 |
| Nunez, EA | 1 |
| Rozenbaum, W | 1 |
| James, JS | 1 |
| Melchior, JC | 1 |
| de Truchis, P | 1 |
| Perronne, C | 1 |
| Gougeon, ML | 1 |
| Mulder, JW | 1 |
| Frissen, PH | 1 |
| Krijnen, P | 1 |
| Endert, E | 1 |
| de Wolf, F | 1 |
| Goudsmit, J | 1 |
| Masterson, JG | 1 |
| Lange, JM | 1 |
| Villette, JM | 1 |
| Bourin, P | 1 |
| Doinel, C | 1 |
| Mansour, I | 1 |
| Fiet, J | 1 |
| Boudou, P | 1 |
| Dreux, C | 1 |
| Roue, R | 1 |
| Debord, M | 1 |
| Levi, F | 1 |
1 review available for dehydroepiandrosterone and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Adrenal androgens and the immune system.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Glands; Androgens; Animals; Arthritis, Rheumatoid; Criti | 2004 |
2 trials available for dehydroepiandrosterone and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Adolescent; Adult; Aged; Dehydroepiandro | 2006 |
An open-label dose-escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Biopterins; CD4-Positive T-Lymphocy | 1993 |
11 other studies available for dehydroepiandrosterone and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Hair levels of steroid, endocannabinoid, and the ratio biomarkers predict viral suppression among people living with HIV/AIDS in China.
Topics: Acquired Immunodeficiency Syndrome; Biomarkers; China; Cross-Sectional Studies; Dehydroepiandrostero | 2022 |
Changes in systemic gonadal and adrenal steroids in asymptomatic human immunodeficiency virus-infected men: relationship with the CD4 cell counts.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Adult; Androgens; Androstenedione; CD4 | 1995 |
Relationship between serum cyclo(His-Pro) concentrations and the nutritional status of HIV-infected patients.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandro | 1994 |
Spotlight on DHEA: a marker for progression of HIV infection?
Topics: Acquired Immunodeficiency Syndrome; Biomarkers; CD4 Lymphocyte Count; Dehydroepiandrosterone; Diseas | 1996 |
Longitudinal study of adrenal steroids in a cohort of HIV-infected patients with hemophilia.
Topics: Acquired Immunodeficiency Syndrome; Adrenocorticotropic Hormone; Adult; CD4 Lymphocyte Count; Cohort | 1996 |
The role of dehydroepiandrosterone in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Dehydroepiandrosterone; Female; Humans; Male; | 1997 |
Effect of interferon alpha on high serum androgen concentrations in HIV positive men with Kaposi's sarcoma.
Topics: Acquired Immunodeficiency Syndrome; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehyd | 1997 |
DHEA and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aging; Dehydroepiandrosterone; Dehydroepiandrostero | 1996 |
Increased serum interferon alpha in HIV-1 associated lipodystrophy syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antiretroviral Therapy, Highly Active; Cross-Sectio | 2002 |
Dehydroepiandrosterone as predictor for progression to AIDS in asymptomatic human immunodeficiency virus-infected men.
Topics: Acquired Immunodeficiency Syndrome; beta 2-Microglobulin; Case-Control Studies; CD4-Positive T-Lymph | 1992 |
Circadian variations in plasma levels of hypophyseal, adrenocortical and testicular hormones in men infected with human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; bet | 1990 |