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dehydroepiandrosterone and Acquired Immune Deficiency Syndrome

dehydroepiandrosterone has been researched along with Acquired Immune Deficiency Syndrome in 14 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"The objective of the study was to relate plasma dehydroepiandrosterone sulfate (DHEA-S) concentrations to the progression of HIV infection in individual HIV-infected men with hemophilia and to obtain information on the cause of DH EA-S alterations."3.69Longitudinal study of adrenal steroids in a cohort of HIV-infected patients with hemophilia. ( Chatterton, RT; Green, D; Grossman, A; Harris, S; Hechter, O, 1996)
" DHEA dosing was flexible (100-400 mg/day)."2.72Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDS. ( Ferrando, SJ; McElhiney, MC; McGrath, PJ; Rabkin, JG; Rabkin, R, 2006)
"Dehydroepiandrosterone (DHEA) is a naturally occurring adrenal steroid reported to have immunomodulatory and antiviral activity in cellular and animal models as well as modest in vitro antiretroviral activity against human immunodeficiency virus (HIV)."2.67An open-label dose-escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease. ( Dyner, TS; Galmarini, M; Geaga, J; Golub, A; Jacobson, MA; Lang, W; Masterson, J; Stites, D; Winger, E, 1993)
"The use of DHEA for the treatment of AIDS shows some promise, although controlled trials have not been performed to evaluate its efficacy."1.30The role of dehydroepiandrosterone in AIDS. ( Abate, MA; Centurelli, MA, 1997)
"DHEA's background and use as an AIDS treatment are reviewed."1.29DHEA and AIDS. ( James, JS, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (71.43)18.2507
2000's3 (21.43)29.6817
2010's0 (0.00)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Chu, L1
Liu, S1
Wu, Y1
Yang, J1
Qiao, S1
Zhou, Y1
Deng, H1
Li, X1
Shen, Z1
Chen, CC1
Parker, CR1
Rabkin, JG1
McElhiney, MC1
Rabkin, R1
McGrath, PJ1
Ferrando, SJ1
Laudat, A1
Blum, L1
Guéchot, J1
Picard, O1
Cabane, J1
Imbert, JC1
Giboudeau, J1
Dyner, TS1
Lang, W1
Geaga, J1
Golub, A1
Stites, D1
Winger, E1
Galmarini, M1
Masterson, J1
Jacobson, MA1
Wisniewski, TL1
Mendel, E1
Morse, EV1
Hilton, CW1
Svec, F1
Brind, J1
Chatterton, RT1
Green, D1
Harris, S1
Grossman, A1
Hechter, O1
Centurelli, MA1
Abate, MA1
Christeff, N2
Gharakhanian, S1
Thobie, N1
Wirbel, E1
Dalle, MT1
Costagliola, D1
Nunez, EA1
Rozenbaum, W1
James, JS1
Melchior, JC1
de Truchis, P1
Perronne, C1
Gougeon, ML1
Mulder, JW1
Frissen, PH1
Krijnen, P1
Endert, E1
de Wolf, F1
Goudsmit, J1
Masterson, JG1
Lange, JM1
Villette, JM1
Bourin, P1
Doinel, C1
Mansour, I1
Fiet, J1
Boudou, P1
Dreux, C1
Roue, R1
Debord, M1
Levi, F1

Reviews

1 review available for dehydroepiandrosterone and Acquired Immune Deficiency Syndrome

ArticleYear
Adrenal androgens and the immune system.
    Seminars in reproductive medicine, 2004, Volume: 22, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Glands; Androgens; Animals; Arthritis, Rheumatoid; Criti

2004

Trials

2 trials available for dehydroepiandrosterone and Acquired Immune Deficiency Syndrome

ArticleYear
Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDS.
    The American journal of psychiatry, 2006, Volume: 163, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Adolescent; Adult; Aged; Dehydroepiandro

2006
An open-label dose-escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Biopterins; CD4-Positive T-Lymphocy

1993

Other Studies

11 other studies available for dehydroepiandrosterone and Acquired Immune Deficiency Syndrome

ArticleYear
Hair levels of steroid, endocannabinoid, and the ratio biomarkers predict viral suppression among people living with HIV/AIDS in China.
    Clinica chimica acta; international journal of clinical chemistry, 2022, Oct-01, Volume: 535

    Topics: Acquired Immunodeficiency Syndrome; Biomarkers; China; Cross-Sectional Studies; Dehydroepiandrostero

2022
Changes in systemic gonadal and adrenal steroids in asymptomatic human immunodeficiency virus-infected men: relationship with the CD4 cell counts.
    European journal of endocrinology, 1995, Volume: 133, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Adult; Androgens; Androstenedione; CD4

1995
Relationship between serum cyclo(His-Pro) concentrations and the nutritional status of HIV-infected patients.
    Southern medical journal, 1994, Volume: 87, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandro

1994
Spotlight on DHEA: a marker for progression of HIV infection?
    The Journal of laboratory and clinical medicine, 1996, Volume: 127, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Biomarkers; CD4 Lymphocyte Count; Dehydroepiandrosterone; Diseas

1996
Longitudinal study of adrenal steroids in a cohort of HIV-infected patients with hemophilia.
    The Journal of laboratory and clinical medicine, 1996, Volume: 127, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adrenocorticotropic Hormone; Adult; CD4 Lymphocyte Count; Cohort

1996
The role of dehydroepiandrosterone in AIDS.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Dehydroepiandrosterone; Female; Humans; Male;

1997
Effect of interferon alpha on high serum androgen concentrations in HIV positive men with Kaposi's sarcoma.
    Journal of clinical pathology, 1997, Volume: 50, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehyd

1997
DHEA and AIDS.
    AIDS treatment news, 1996, Jan-19, Issue:no 239

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aging; Dehydroepiandrosterone; Dehydroepiandrostero

1996
Increased serum interferon alpha in HIV-1 associated lipodystrophy syndrome.
    European journal of clinical investigation, 2002, Volume: 32, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antiretroviral Therapy, Highly Active; Cross-Sectio

2002
Dehydroepiandrosterone as predictor for progression to AIDS in asymptomatic human immunodeficiency virus-infected men.
    The Journal of infectious diseases, 1992, Volume: 165, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; beta 2-Microglobulin; Case-Control Studies; CD4-Positive T-Lymph

1992
Circadian variations in plasma levels of hypophyseal, adrenocortical and testicular hormones in men infected with human immunodeficiency virus.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; bet

1990