dehydroepiandrosterone has been researched along with Ache in 16 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with fibromyalgia (FM) consistently have adrenal hyporesponsiveness and low dehydroepiandrosterone (DHEA) levels." | 9.11 | A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia. ( Aubry-Rozier, B; Berner, IC; Finckh, A; So, AK, 2005) |
| "The purpose of this study was to examine the effect of DHEA (Dehydroepiandrosterone) on muscle weight and Type I and II fiber cross-sectional area of affected and unaffected hindlimb muscles in rats with neuropathic pain induced by unilateral peripheral nerve injury." | 7.75 | [Effect of dehydroepiandrosterone on affected and unaffected hindlimb muscles in rats with neuropathic pain induced by unilateral peripheral nerve injury]. ( An, GJ; Choe, MA, 2009) |
| "We investigated the role and mechanism of action of dehydroepiandrosterone (DHEA) produced by the spinal cord (SC) in pain modulation in sciatic-neuropathic and control rats." | 7.74 | Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord. ( Kibaly, C; Mensah-Nyagan, AG; Meyer, L; Patte-Mensah, C, 2008) |
| "Patients with fibromyalgia (FM) consistently have adrenal hyporesponsiveness and low dehydroepiandrosterone (DHEA) levels." | 5.11 | A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia. ( Aubry-Rozier, B; Berner, IC; Finckh, A; So, AK, 2005) |
| "This study aimed to investigate whether the sex steroid precursor hormone dehydroepiandrosterone sulphate (DHEA-S), sex hormone-binding globulin (SHBG) and testosterone (TT) are associated with temporomandibular (TM) pain on palpation in male adolescents." | 4.31 | Sex hormones associated with temporomandibular pain on palpation in male adolescents-Results of the epidemiologic LIFE child study. ( Biemann, R; Hirsch, C; Kiess, W; Körner, A; Schierz, O; Schrock, A; Türp, JC, 2023) |
| " The secondary objectives were as follows: to describe demographic and clinical characteristics of male patients with FM; to evaluate basal levels of dehydroepiandrosterone sulfate (DHEAS) and total testosterone in both groups; and to investigate the relationship among pain, tender points, anxiety, and depression in these patients." | 3.76 | A comparison of quality of life, demographic and clinical characteristics of Brazilian men with fibromyalgia syndrome with male patients with depression. ( Helfenstein, M; Heymann, RE; Pollak, DF; Yoshikawa, GT, 2010) |
| "Allopregnanolone levels were inversely associated with low back pain (P=0." | 3.76 | Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001. ( Calnaido, RP; Hamer, RM; Keefe, FJ; Kilts, JD; Marx, CE; Massing, MW; Morey, RA; Naylor, JC; Parke, G; Payne, VM; Shampine, LJ; Strauss, JL; Tupler, LA; Youssef, NA, 2010) |
| "The purpose of this study was to examine the effect of DHEA (Dehydroepiandrosterone) on muscle weight and Type I and II fiber cross-sectional area of affected and unaffected hindlimb muscles in rats with neuropathic pain induced by unilateral peripheral nerve injury." | 3.75 | [Effect of dehydroepiandrosterone on affected and unaffected hindlimb muscles in rats with neuropathic pain induced by unilateral peripheral nerve injury]. ( An, GJ; Choe, MA, 2009) |
| "We investigated the role and mechanism of action of dehydroepiandrosterone (DHEA) produced by the spinal cord (SC) in pain modulation in sciatic-neuropathic and control rats." | 3.74 | Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord. ( Kibaly, C; Mensah-Nyagan, AG; Meyer, L; Patte-Mensah, C, 2008) |
| "Patients with temporomandibular disorders (TMD) commonly experience myofascial and joint pain, pain-related disability, and other pain conditions including depression." | 1.43 | Association of pain intensity, pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders. ( Ahn, RS; Jo, KB; Lee, IG; Lee, SC; Lee, YJ; Park, JY, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 4 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahn, RS | 2 |
| Park, JW | 1 |
| Park, IS | 1 |
| Shin, HJ | 1 |
| Ryu, JH | 1 |
| Oh, AY | 1 |
| Park, HY | 1 |
| Do, SH | 1 |
| Hirsch, C | 1 |
| Schierz, O | 1 |
| Körner, A | 1 |
| Kiess, W | 1 |
| Biemann, R | 1 |
| Schrock, A | 1 |
| Türp, JC | 1 |
| Pradeep, A | 1 |
| Birerdinc, A | 1 |
| Branigan, T | 1 |
| Phan, V | 1 |
| Morris, H | 1 |
| Shah, J | 1 |
| DeStefano, S | 1 |
| Sikdar, S | 1 |
| Srbely, J | 1 |
| Kumbhare, D | 1 |
| Stecco, A | 1 |
| Paik, J | 1 |
| Gerber, LH | 1 |
| Kapritsou, M | 1 |
| Bozas, E | 1 |
| Stavrianos, S | 1 |
| Salatas, K | 1 |
| Plastiras, A | 1 |
| Pistolas, K | 1 |
| Fyrfiris, N | 1 |
| Kotrotsiou, M | 1 |
| Konstantinou, EA | 1 |
| Bachmann, G | 1 |
| Phillips, N | 1 |
| Huang, K | 1 |
| Cai, HL | 1 |
| Wu, LD | 1 |
| Cecconello, AL | 1 |
| Torres, IL | 1 |
| Oliveira, C | 1 |
| Zanini, P | 1 |
| Niches, G | 1 |
| Ribeiro, MF | 1 |
| Jo, KB | 1 |
| Lee, YJ | 1 |
| Lee, IG | 1 |
| Lee, SC | 1 |
| Park, JY | 1 |
| Colameco, S | 1 |
| Coren, JS | 1 |
| Yoshikawa, GT | 1 |
| Heymann, RE | 1 |
| Helfenstein, M | 1 |
| Pollak, DF | 1 |
| Choe, MA | 1 |
| An, GJ | 1 |
| Kilts, JD | 1 |
| Tupler, LA | 1 |
| Keefe, FJ | 1 |
| Payne, VM | 1 |
| Hamer, RM | 1 |
| Naylor, JC | 1 |
| Calnaido, RP | 1 |
| Morey, RA | 1 |
| Strauss, JL | 1 |
| Parke, G | 1 |
| Massing, MW | 1 |
| Youssef, NA | 1 |
| Shampine, LJ | 1 |
| Marx, CE | 1 |
| Mizota, K | 1 |
| Yoshida, A | 1 |
| Uchida, H | 1 |
| Fujita, R | 1 |
| Ueda, H | 1 |
| Finckh, A | 1 |
| Berner, IC | 1 |
| Aubry-Rozier, B | 1 |
| So, AK | 1 |
| Blackman, MR | 1 |
| Muniyappa, R | 1 |
| Wilson, M | 1 |
| Moquin, BE | 1 |
| Baldwin, HL | 1 |
| Wong, KA | 1 |
| Snyder, C | 1 |
| Magalnick, M | 1 |
| Alli, S | 1 |
| Reynolds, J | 1 |
| Steinberg, SM | 1 |
| Goldbach-Mansky, R | 1 |
| Kibaly, C | 1 |
| Meyer, L | 1 |
| Patte-Mensah, C | 1 |
| Mensah-Nyagan, AG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Relationship Between Central Sensitization and Alteration of Circulating Neurosteroid Following Bilateral Total Knee Arthroplasty[NCT03298711] | 69 participants (Actual) | Observational | 2017-11-20 | Completed | |||
| Suppression of the Growth Hormone/ Insulin-Like Growth Factor-1 (GH/IGF-1) Axis in Women With Rheumatoid Arthritis[NCT00034060] | Phase 2 | 36 participants | Interventional | 2002-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dehydroepiandrosterone and Ache
| Article | Year |
|---|---|
Potential of dehydroepiandrosterone in modulating osteoarthritis-related pain.
Topics: Animals; Dehydroepiandrosterone; Humans; Osteoarthritis; Pain | 2019 |
Opioid-induced endocrinopathy.
Topics: Adrenal Glands; Analgesics, Opioid; Dehydroepiandrosterone; Endocrine System Diseases; Humans; Hypog | 2009 |
2 trials available for dehydroepiandrosterone and Ache
| Article | Year |
|---|---|
The Total Intra Venous Anesthesia Effect Versus Volatile Anesthesia, on Stress and Pain Levels, in Patients Undergoing Breast Reconstruction in Ambulatory Surgery Center Total Intra Venous Anesthesia Protocol and Stress Response.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Dehydroepiandrosterone; Humans; Hydrocortisone; | 2024 |
A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia.
Topics: Aged; Cognition; Complementary Therapies; Cross-Over Studies; Dehydroepiandrosterone; Dietary Supple | 2005 |
12 other studies available for dehydroepiandrosterone and Ache
| Article | Year |
|---|---|
The Involvement of the Hypothalamus-Pituitary-Adrenal Axis in the Development of Hyperalgesia during the Early Postoperative Period.
Topics: Dehydroepiandrosterone; Humans; Hydrocortisone; Hyperalgesia; Hypothalamo-Hypophyseal System; Pain; | 2023 |
Sex hormones associated with temporomandibular pain on palpation in male adolescents-Results of the epidemiologic LIFE child study.
Topics: Adolescent; Child; Cross-Sectional Studies; Dehydroepiandrosterone; Gonadal Steroid Hormones; Humans | 2023 |
Evidence for an association of serum microanalytes and myofascial pain syndrome.
Topics: Acetylcholine; Adult; Brain-Derived Neurotrophic Factor; Cytokines; Dehydroepiandrosterone; Female; | 2023 |
Dehydroepiandrosterone use in postmenopausal women: an androgenic option for managing sexual pain caused by vulvovaginal atrophy.
Topics: Atrophy; Dehydroepiandrosterone; Female; Humans; Menopause; Pain; Postmenopause | 2017 |
DHEA administration modulates stress-induced analgesia in rats.
Topics: Analgesics; Analysis of Variance; Animals; Corticosterone; Dehydroepiandrosterone; Disease Models, A | 2016 |
Association of pain intensity, pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders.
Topics: Adult; Chronic Pain; Circadian Rhythm; Comorbidity; Dehydroepiandrosterone; Depression; Depressive D | 2016 |
A comparison of quality of life, demographic and clinical characteristics of Brazilian men with fibromyalgia syndrome with male patients with depression.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Anxiety; Brazil; Dehydroepiandrosterone; Demogr | 2010 |
[Effect of dehydroepiandrosterone on affected and unaffected hindlimb muscles in rats with neuropathic pain induced by unilateral peripheral nerve injury].
Topics: Animals; Body Weight; Dehydroepiandrosterone; Disease Models, Animal; Eating; Hindlimb; Male; Muscle | 2009 |
Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.
Topics: Adult; Afghanistan; Brain Injuries; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrom | 2010 |
Novel type of Gq/11 protein-coupled neurosteroid receptor sensitive to endocrine disrupting chemicals in mast cell line (RBL-2H3).
Topics: Animals; Behavior, Animal; beta-N-Acetylhexosaminidases; Binding, Competitive; Cattle; Cell Line, Tu | 2005 |
Diurnal secretion of growth hormone, cortisol, and dehydroepiandrosterone in pre- and perimenopausal women with active rheumatoid arthritis: a pilot case-control study.
Topics: Adult; Arthritis, Rheumatoid; Blood Chemical Analysis; Case-Control Studies; Circadian Rhythm; Dehyd | 2007 |
Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord.
Topics: Animals; Base Sequence; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cy | 2008 |