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dehydroepiandrosterone and Acanthosis Nigricans

dehydroepiandrosterone has been researched along with Acanthosis Nigricans in 5 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Acanthosis Nigricans: A circumscribed melanosis consisting of a brown-pigmented, velvety verrucosity or fine papillomatosis appearing in the axillae and other body folds. It occurs in association with endocrine disorders, underlying malignancy, administration of certain drugs, or as in inherited disorder.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to define the relationship among the circulating insulin level (IRI), the MCR of dehydroepiandrosterone (MCR-D), and the production rate of DHEA (PR-D) in 10 women with the polycystic ovary syndrome and acanthosis nigricans (PCOS-AN)."7.68Bimodal correlation between the circulating insulin level and the production rate of dehydroepiandrosterone: positive correlation in controls and negative correlation in the polycystic ovary syndrome with acanthosis nigricans. ( Farah, MJ; Givens, JR; Kitabchi, AE, 1990)
"These results indicate that acute hyperinsulinemia of 12- to 16-h duration does not increase serum testosterone or DHEA-S concentrations and, indeed, can cause a decline in serum DHEA-S levels in both normal women and the single woman studied with hyperandrogenism, insulin resistance, and acanthosis nigricans."5.27The effects of hyperinsulinemia on serum testosterone, progesterone, dehydroepiandrosterone sulfate, and cortisol levels in normal women and in a woman with hyperandrogenism, insulin resistance, and acanthosis nigricans. ( Blackard, WG; Clore, JN; Nestler, JE; Strauss, JF, 1987)
"The objective of this study was to define the relationship among the circulating insulin level (IRI), the MCR of dehydroepiandrosterone (MCR-D), and the production rate of DHEA (PR-D) in 10 women with the polycystic ovary syndrome and acanthosis nigricans (PCOS-AN)."3.68Bimodal correlation between the circulating insulin level and the production rate of dehydroepiandrosterone: positive correlation in controls and negative correlation in the polycystic ovary syndrome with acanthosis nigricans. ( Farah, MJ; Givens, JR; Kitabchi, AE, 1990)
"Their insulin resistance was significantly greater than that in a control group with comparable obesity."1.27Obesity, acanthosis nigricans, insulin resistance, and hyperandrogenemia: pediatric perspective and natural history. ( Cavallo, A; Meyer, WJ; Peters, EJ; Prince, MJ; Richards, GE; Smith, ER; Stuart, CA, 1985)
"These results indicate that acute hyperinsulinemia of 12- to 16-h duration does not increase serum testosterone or DHEA-S concentrations and, indeed, can cause a decline in serum DHEA-S levels in both normal women and the single woman studied with hyperandrogenism, insulin resistance, and acanthosis nigricans."1.27The effects of hyperinsulinemia on serum testosterone, progesterone, dehydroepiandrosterone sulfate, and cortisol levels in normal women and in a woman with hyperandrogenism, insulin resistance, and acanthosis nigricans. ( Blackard, WG; Clore, JN; Nestler, JE; Strauss, JF, 1987)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bener, A1
Lestringant, GG1
Townsend, A1
Al-Mulla, HM1
Farah, MJ1
Givens, JR1
Kitabchi, AE1
Richards, GE1
Cavallo, A1
Meyer, WJ1
Prince, MJ1
Peters, EJ1
Stuart, CA1
Smith, ER1
Nestler, JE1
Clore, JN1
Strauss, JF1
Blackard, WG1
Alper, MM1
Garner, PR1

Other Studies

5 other studies available for dehydroepiandrosterone and Acanthosis Nigricans

ArticleYear
Association of acanthosis nigricans with risk of diabetes mellitus, and hormonal disturbances in arabian females: case-control study.
    Maturitas, 2001, Oct-31, Volume: 40, Issue:1

    Topics: Acanthosis Nigricans; Adolescent; Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Body Mass

2001
Bimodal correlation between the circulating insulin level and the production rate of dehydroepiandrosterone: positive correlation in controls and negative correlation in the polycystic ovary syndrome with acanthosis nigricans.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:4

    Topics: Acanthosis Nigricans; Adolescent; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fas

1990
Obesity, acanthosis nigricans, insulin resistance, and hyperandrogenemia: pediatric perspective and natural history.
    The Journal of pediatrics, 1985, Volume: 107, Issue:6

    Topics: Acanthosis Nigricans; Adolescent; Androstenedione; Body Weight; Child; Dehydroepiandrosterone; Femal

1985
The effects of hyperinsulinemia on serum testosterone, progesterone, dehydroepiandrosterone sulfate, and cortisol levels in normal women and in a woman with hyperandrogenism, insulin resistance, and acanthosis nigricans.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 64, Issue:1

    Topics: Acanthosis Nigricans; Adult; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fema

1987
Elevated serum dehydroepiandrosterone sulfate levels in patients with insulin resistance, hirsutism, and acanthosis nigricans.
    Fertility and sterility, 1987, Volume: 47, Issue:2

    Topics: Acanthosis Nigricans; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Follicle Stimu

1987