dehydroandrographolide has been researched along with Zika-Virus-Infection* in 1 studies
1 other study(ies) available for dehydroandrographolide and Zika-Virus-Infection
| Article | Year |
|---|---|
Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5.
Infection by Zika virus (ZIKV), a mosquito-transmitted arbovirus and a member of Flavivirus, could make pediatric microcephaly and Guillain-Barré syndrome, which remains an ongoing global threat. The efficient antivirals to ZIKV infection are of great medical need. Andrographolide and its analogues were discovered to be active against flaviviral infection. In this study, we discovered some dehydroandrographolide derivatives of 3-oximido- or 3-alcohol-19-hindered ether to be potent anti-ZIKV agents with low cytotoxicities (CC Topics: Animals; Antiviral Agents; Child; Ether; Humans; Molecular Docking Simulation; Virus Replication; Zika Virus; Zika Virus Infection | 2022 |