Page last updated: 2024-09-02

deguelin and Neoplasms

deguelin has been researched along with Neoplasms in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L1
Li, W; Ma, C; Wang, G; Xie, S; Xu, F; Xu, J; Xu, S; Yao, H; Zhu, Z1
Lin, ZY; Wu, L; Yao, TZ; Yun, QZ; Zhang, TW1
Aggarwal, D; Aggarwal, V; Bishayee, A; Kaur, G; Kumar, M; Loka, M; Masurkar, A; Mittal, S; Sak, K; Sethi, G; Tuli, HS; Varol, M1
Bhave, AS; Goh, BC; Kumar, AP; Lam, WS; Lee, SC; Lobie, PE; Marican, AABH; Sethi, G; Syn, NL; Varughese, RS; Viganeshwari, SH; Wang, J; Wang, L; Wong, AL1
Bilecová-Rabajdová, M; Birková, A; Durovcová, E; Gregová, K; Mareková, M; Urban, P1
Hong, SS; Hong, WK; Jin, Q; Kim, KW; Kim, WY; Lee, HY; Myers, JN; Oh, SH; Park, HJ; Suh, YG; Woo, JK; Yazici, YD1
Hong, WK; Jeong, JW; Jin, Q; Kang, HJ; Kim, KW; Lee, HY; Oh, SH; Woo, JK1

Reviews

5 review(s) available for deguelin and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction

2015
Pharmacological basis and new insights of deguelin concerning its anticancer effects.
    Pharmacological research, 2021, Volume: 174

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Cycle; Humans; Neoplasm Metastasis; Neoplasms; Nucleophosmin; Rotenone

2021
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies.
    Pharmacological research, 2021, Volume: 166

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogenesis; Cell Proliferation; Humans; Neoplasms; Rotenone; Signal Transduction

2021
Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential.
    Cancer, 2019, 06-01, Volume: 125, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Development; Humans; Neoplasms; Rotenone

2019
Naturally occurring substances and their role in chemo-protective effects.
    Central European journal of public health, 2013, Volume: 21, Issue:4

    Topics: Biological Products; Calcitriol; Estrogen Receptor Modulators; Humans; Neoplasms; Polyphenols; Protective Agents; Retinoids; Rotenone; Sulfur Compounds; Terpenes

2013

Other Studies

3 other study(ies) available for deguelin and Neoplasms

ArticleYear
Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; HSP90 Heat-Shock Proteins; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Proteasome Endopeptidase Complex; Rotenone; Structure-Activity Relationship

2019
Structural basis for depletion of heat shock protein 90 client proteins by deguelin.
    Journal of the National Cancer Institute, 2007, Jun-20, Volume: 99, Issue:12

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Binding Sites; Binding, Competitive; Cell Growth Processes; Female; Fructose-Bisphosphate Aldolase; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Mice; Mice, Nude; Models, Molecular; Neoplasms; Reactive Oxygen Species; Rotenone; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2007
Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha.
    International journal of cancer, 2008, Jan-01, Volume: 122, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Aorta; Blotting, Western; Cell Hypoxia; Cell Movement; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Culture Media, Conditioned; Cysteine Proteinase Inhibitors; Drug Combinations; Endothelium, Vascular; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Laminin; Leupeptins; Luciferases; Mice; Neoplasms; Neovascularization, Pathologic; Proteasome Endopeptidase Complex; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Tumor Cells, Cultured; Ubiquitin; Vascular Endothelial Growth Factor A; Zebrafish

2008