deferoxamine has been researched along with Uveitis in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Uveitis: Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the effect of deferoxamine, an effective iron chelator, on experimental autoimmune uveitis." | 7.68 | Effect of deferoxamine on retinal lipid peroxidation in experimental uveitis. ( Rao, NA; Walker, J; Wu, GS, 1993) |
| " Treatment of experimental uveitis in Lewis rats with an iron chelator, deferoxamine mesylate, resulted in marked reduction in choroidal inflammation and suppression of retinal damage." | 3.67 | Effect of iron chelation on severity of ocular inflammation in an animal model. ( Fernandez, MA; Marak, GE; Rao, NA; Romero, JL; Sevanian, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, GS | 1 |
| Walker, J | 1 |
| Rao, NA | 2 |
| Romero, JL | 1 |
| Fernandez, MA | 1 |
| Sevanian, A | 1 |
| Marak, GE | 1 |
2 other studies available for deferoxamine and Uveitis
| Article | Year |
|---|---|
Effect of deferoxamine on retinal lipid peroxidation in experimental uveitis.
Topics: Animals; Choroid; Deferoxamine; Female; Free Radicals; Infusion Pumps, Implantable; Lipid Peroxidati | 1993 |
Effect of iron chelation on severity of ocular inflammation in an animal model.
Topics: Animals; Anti-Inflammatory Agents; Antigens; Arrestin; Choroiditis; Deferoxamine; Disease Models, An | 1986 |