deferoxamine has been researched along with Trypanosomiasis, African in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amisigo, CM | 1 |
| Antwi, CA | 1 |
| Adjimani, JP | 1 |
| Gwira, TM | 1 |
| Comini, MA | 1 |
| Rettig, J | 1 |
| Dirdjaja, N | 1 |
| Hanschmann, EM | 1 |
| Berndt, C | 1 |
| Krauth-Siegel, RL | 1 |
2 other studies available for deferoxamine and Trypanosomiasis, African
| Article | Year |
|---|---|
In vitro anti-trypanosomal effects of selected phenolic acids on Trypanosoma brucei.
Topics: Animals; Cell Proliferation; Cell Survival; Deferoxamine; Diminazene; Drug Resistance; Gallic Acid; | 2019 |
Monothiol glutaredoxin-1 is an essential iron-sulfur protein in the mitochondrion of African trypanosomes.
Topics: Animals; Cytosol; Deferoxamine; Gene Expression Regulation, Enzymologic; Glutaredoxins; Humans; Hydr | 2008 |