deferoxamine has been researched along with Thrombosis in 19 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ga-67-DFO-DAS-fibrinogen (Ga-fbg) scintigraphy, a new radiopharmaceutical method, was performed for detecting intraventricular thrombi following acute myocardial infarction in five patients." | 7.67 | [Detection of left ventricular thrombi after acute myocardial infarction using Ga-67-DFO-DAS-fibrinogen]. ( Akioka, K; Hirota, K; Itagane, H; Ochi, H; Oku, H; Takeda, T; Takeuchi, K; Teragaki, M; Yasuda, M, 1988) |
| " In July 1996, deferoxamine was administered for iron overload." | 4.80 | [Development of arterial thrombus of Mucorales hyphae during deferoxamine therapy in a patient with aplastic anemia in transformation to myelodysplastic syndrome]. ( Kajiguchi, T; Miyata, Y; Saito, M; Takeyama, H, 2000) |
| "Ga-67-DFO-DAS-fibrinogen (Ga-fbg) scintigraphy, a new radiopharmaceutical method, was performed for detecting intraventricular thrombi following acute myocardial infarction in five patients." | 3.67 | [Detection of left ventricular thrombi after acute myocardial infarction using Ga-67-DFO-DAS-fibrinogen]. ( Akioka, K; Hirota, K; Itagane, H; Ochi, H; Oku, H; Takeda, T; Takeuchi, K; Teragaki, M; Yasuda, M, 1988) |
| "Until a suitable thrombus-specific radiopharmaceutical becomes generally available, many hospitals will continue to attempt to make a diagnosis with nonspecific radiopharmaceuticals that can at best provide blood pool images to indicate filling defects." | 2.38 | Radiopharmaceuticals for thrombus detection. ( Knight, LC, 1990) |
| "The occlusive thrombus formation time was significantly extended by DFX." | 1.30 | The effects of desferrioxamine on thrombus formation in injured microvessels of the rabbit ear. ( Hashimoto, I; Nakanishi, H; Shono, Y; Tanaka, S, 1999) |
| "The 11 patients with chronic renal failure had the operation of the internal A-V shunt." | 1.28 | [Evaluation of thrombus scintigraphy using 67Ga-deferoxamine-dialdehydestarch-fibrinogen in patients with internal A-V shunt]. ( Hachiya, Y; Hirata, K; Iida, M; Kawamura, Y; Matsuzaki, K; Morishita, T; Noguchi, M; Obara, T; Uchi, T; Yamazaki, J, 1990) |
| "Its implication in thrombus accumulation is discussed." | 1.27 | In vivo kinetics and thrombus accumulation of 67Ga-labeled urokinase. ( Horiuchi, K; Ohmomo, Y; Saji, H; Tanaka, C; Torizuka, K; Yamauchi, Y; Yokoyama, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (36.84) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| West, M | 1 |
| Malik, GA | 1 |
| Pollock, JC | 1 |
| Kubota, N | 2 |
| Miyazawa, K | 2 |
| Shoji, N | 2 |
| Sumi, M | 2 |
| Nakajima, A | 2 |
| Kimura, Y | 2 |
| Oshiro, H | 2 |
| Ebihara, Y | 2 |
| Ohyashiki, K | 2 |
| Nigri, GR | 1 |
| Kossodo, S | 1 |
| Waterman, P | 1 |
| Fungaloi, P | 1 |
| LaMuraglia, GM | 1 |
| Sözen, M | 1 |
| Karaaslan, C | 1 |
| Oner, R | 1 |
| Gümrük, F | 1 |
| Ozdemir, MA | 1 |
| Altay, C | 1 |
| Gürgey, A | 1 |
| Oner, C | 1 |
| Borgna-Pignatti, C | 1 |
| Rugolotto, S | 1 |
| De Stefano, P | 1 |
| Zhao, H | 1 |
| Cappellini, MD | 1 |
| Del Vecchio, GC | 1 |
| Romeo, MA | 1 |
| Forni, GL | 1 |
| Gamberini, MR | 1 |
| Ghilardi, R | 1 |
| Piga, A | 1 |
| Cnaan, A | 1 |
| Wood, KC | 1 |
| Hebbel, RP | 1 |
| Granger, DN | 1 |
| Ohmomo, Y | 2 |
| Yokoyama, A | 2 |
| Suzuki, J | 1 |
| Tanaka, H | 1 |
| Yamamoto, K | 1 |
| Horiuchi, K | 2 |
| Ishii, Y | 1 |
| Torizuka, K | 2 |
| Luo, Z | 1 |
| Harada, T | 1 |
| London, S | 1 |
| Gajdusek, C | 1 |
| Mayberg, MR | 1 |
| Hashimoto, I | 1 |
| Nakanishi, H | 1 |
| Shono, Y | 1 |
| Tanaka, S | 1 |
| Miyata, Y | 1 |
| Kajiguchi, T | 1 |
| Saito, M | 1 |
| Takeyama, H | 1 |
| Knight, LC | 1 |
| Yamazaki, J | 1 |
| Uchi, T | 1 |
| Kawamura, Y | 1 |
| Iida, M | 1 |
| Hachiya, Y | 1 |
| Matsuzaki, K | 1 |
| Morishita, T | 1 |
| Obara, T | 1 |
| Hirata, K | 1 |
| Noguchi, M | 1 |
| Sakoda, S | 1 |
| Kinoshita, M | 1 |
| Suzuki, T | 1 |
| Russell, SJ | 1 |
| Giles, FJ | 1 |
| Edwards, D | 1 |
| Porter, J | 1 |
| Hardmann, S | 1 |
| Harrison, R | 1 |
| Itagane, H | 1 |
| Hirota, K | 1 |
| Teragaki, M | 1 |
| Akioka, K | 1 |
| Yasuda, M | 1 |
| Oku, H | 1 |
| Takeuchi, K | 1 |
| Takeda, T | 1 |
| Ochi, H | 1 |
| Kawasaki, Y | 1 |
| Yamauchi, Y | 1 |
| Saji, H | 1 |
| Tanaka, C | 1 |
| Raitta, C | 1 |
| Vannas, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Iron-mediated Vascular Disease in Sickle Cell Disease.[NCT01239901] | 150 participants (Actual) | Observational | 2009-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for deferoxamine and Thrombosis
| Article | Year |
|---|---|
[Development of arterial thrombus of Mucorales hyphae during deferoxamine therapy in a patient with aplastic anemia in transformation to myelodysplastic syndrome].
Topics: Anemia, Aplastic; Chelating Agents; Deferoxamine; Fatal Outcome; Female; Humans; Iron Overload; Midd | 2000 |
Radiopharmaceuticals for thrombus detection.
Topics: Antibodies, Monoclonal; Blood Platelets; Deferoxamine; Fibrinogen; Fibrinolysin; Humans; Iodine Radi | 1990 |
17 other studies available for deferoxamine and Thrombosis
| Article | Year |
|---|---|
Surgical resection of multiple right atrial masses in a child with beta thalassaemia and receiving desferioxamine.
Topics: Adolescent; beta-Thalassemia; Calcinosis; Cardiac Catheterization; Cardiomyopathies; Catheters, Indw | 2003 |
A massive intraventricular thrombosis by disseminated mucormycosis in a patient with myelodysplastic syndrome during deferoxamine therapy.
Topics: Aged; Cerebral Ventricle Neoplasms; Cerebral Ventricles; Deferoxamine; Fatal Outcome; Humans; Male; | 2003 |
A massive intraventricular thrombosis by disseminated mucormycosis in a patient with myelodysplastic syndrome during deferoxamine therapy.
Topics: Aged; Anemia, Refractory; Deferoxamine; Echocardiography; Fatal Outcome; Heart Diseases; Heart Ventr | 2003 |
Free radical attenuation prevents thrombosis and enables photochemical inhibition of vein graft intimal hyperplasia.
Topics: Animals; Antibodies, Monoclonal; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cell | 2004 |
Severe hemolytic anemia associated with Hb Volga [beta27(B9)Ala-->Asp]: GCC-->GAC at codon 27 in a Turkish family.
Topics: Adult; Anemia, Hemolytic, Congenital; Blood Protein Electrophoresis; Child, Preschool; Codon; Combin | 2004 |
Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine.
Topics: Adult; Age Factors; Arrhythmias, Cardiac; Blood Transfusion; Chelation Therapy; Cohort Studies; Defe | 2004 |
Endothelial cell NADPH oxidase mediates the cerebral microvascular dysfunction in sickle cell transgenic mice.
Topics: Allopurinol; Anemia, Sickle Cell; Animals; Bone Marrow Transplantation; Brain; Deferoxamine; Endothe | 2005 |
67 Ga-labeled human fibrinogen: a new promising thrombus imaging agent.
Topics: Animals; Deferoxamine; Femoral Vein; Fibrinogen; Gallium Radioisotopes; Humans; Male; Mice; Rabbits; | 1982 |
Antioxidant and iron-chelating agents in cerebral vasospasm.
Topics: Animals; Antioxidants; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Femoral Artery | 1995 |
The effects of desferrioxamine on thrombus formation in injured microvessels of the rabbit ear.
Topics: Animals; Arterioles; Deferoxamine; Ear; Iron Chelating Agents; Rabbits; Thrombosis; Venules | 1999 |
[Evaluation of thrombus scintigraphy using 67Ga-deferoxamine-dialdehydestarch-fibrinogen in patients with internal A-V shunt].
Topics: Adolescent; Adult; Arteriovenous Shunt, Surgical; Deferoxamine; Female; Fibrinogen; Gallium Radioiso | 1990 |
[Left ventricular thrombi detected by Ga-67-DFO-DAS-fibrinogen imaging and two-dimensional echocardiography].
Topics: Adult; Aged; Deferoxamine; Depth Perception; Echocardiography; Female; Fibrinogen; Gallium Radioisot | 1989 |
Perforation of superior vena cava by indwelling central venous catheters.
Topics: Adult; Catheters, Indwelling; Child; Deferoxamine; Female; Humans; Infusions, Intravenous; Male; Mid | 1987 |
[Detection of left ventricular thrombi after acute myocardial infarction using Ga-67-DFO-DAS-fibrinogen].
Topics: Adult; Deferoxamine; Echocardiography; Female; Fibrinogen; Gallium Radioisotopes; Heart Diseases; He | 1988 |
[Thrombus scintigraphy with Ga-67 DFO-DAS-fibrinogen. II. Clinical applications of Ga-67 DFO-DAS-fibrinogen].
Topics: Adult; Aged; Deferoxamine; Female; Fibrinogen; Gallium Radioisotopes; Humans; Male; Middle Aged; Rad | 1987 |
In vivo kinetics and thrombus accumulation of 67Ga-labeled urokinase.
Topics: Animals; Deferoxamine; Gallium Radioisotopes; Humans; Kinetics; Mice; Protein Binding; Rabbits; Radi | 1985 |
Desferrioxamine B in the prevention of hemorrhagic glaucoma.
Topics: Adult; Aged; Deferoxamine; Female; Glaucoma; Humans; Male; Middle Aged; Retinal Hemorrhage; Retinal | 1969 |