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deferoxamine and Spinal Diseases

deferoxamine has been researched along with Spinal Diseases in 4 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Spinal Diseases: Diseases involving the SPINE.

Research Excerpts

ExcerptRelevanceReference
"A new constellation of spinal changes are observed in homozygous beta-thalassemia major (HBT) patients receiving deferoxamine (DF), an iron-chelating drug used in combination with transfusion therapy in certain anemic syndromes."7.68Spinal deformities in deferoxamine-treated homozygous beta-thalassemia major patients. ( Babyn, PS; Hartkamp, MJ; Olivieri, F, 1993)
"A new constellation of spinal changes are observed in homozygous beta-thalassemia major (HBT) patients receiving deferoxamine (DF), an iron-chelating drug used in combination with transfusion therapy in certain anemic syndromes."3.68Spinal deformities in deferoxamine-treated homozygous beta-thalassemia major patients. ( Babyn, PS; Hartkamp, MJ; Olivieri, F, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Orzincolo, C1
Castaldi, G1
Scutellari, PN1
Hartkamp, MJ1
Babyn, PS1
Olivieri, F1
Levin, TL1
Sheth, S1
Berdon, WE1
Ruzal-Shapiro, C1
Piomelli, S1
Naselli, A1
Vignolo, M1
Di Battista, E1
Garzia, P1
Forni, GL1
Traverso, T1
Aicardi, G1

Other Studies

4 other studies available for deferoxamine and Spinal Diseases

ArticleYear
Platyspondyly in treated beta-thalassemia.
    European journal of radiology, 1994, Volume: 18, Issue:2

    Topics: Adolescent; beta-Thalassemia; Blood Transfusion; Body Height; Child; Combined Modality Therapy; Defe

1994
Spinal deformities in deferoxamine-treated homozygous beta-thalassemia major patients.
    Pediatric radiology, 1993, Volume: 23, Issue:7

    Topics: Adolescent; beta-Thalassemia; Calcinosis; Child; Child, Preschool; Deferoxamine; Dose-Response Relat

1993
Deferoxamine-induced platyspondyly in hypertransfused thalassemic patients.
    Pediatric radiology, 1995, Volume: 25 Suppl 1

    Topics: Adult; beta-Thalassemia; Body Height; Deferoxamine; Female; Follow-Up Studies; Hemosiderosis; Humans

1995
Long-term follow-up of skeletal dysplasia in thalassaemia major.
    Journal of pediatric endocrinology & metabolism : JPEM, 1998, Volume: 11 Suppl 3

    Topics: Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Body Height; Bone Diseases, Developmental; D

1998