Page last updated: 2024-10-25

deferoxamine and Retinitis

deferoxamine has been researched along with Retinitis in 1 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Retinitis: Inflammation of the RETINA. It is rarely limited to the retina, but is commonly associated with diseases of the choroid (CHORIORETINITIS) and of the OPTIC DISK (neuroretinitis).

Research Excerpts

ExcerptRelevanceReference
" Treatment of experimental uveitis in Lewis rats with an iron chelator, deferoxamine mesylate, resulted in marked reduction in choroidal inflammation and suppression of retinal damage."3.67Effect of iron chelation on severity of ocular inflammation in an animal model. ( Fernandez, MA; Marak, GE; Rao, NA; Romero, JL; Sevanian, A, 1986)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rao, NA1
Romero, JL1
Fernandez, MA1
Sevanian, A1
Marak, GE1

Other Studies

1 other study available for deferoxamine and Retinitis

ArticleYear
Effect of iron chelation on severity of ocular inflammation in an animal model.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antigens; Arrestin; Choroiditis; Deferoxamine; Disease Models, An

1986