deferoxamine has been researched along with Retinitis Pigmentosa in 5 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Retinitis Pigmentosa: Hereditary, progressive degeneration of the retina due to death of ROD PHOTORECEPTORS initially and subsequent death of CONE PHOTORECEPTORS. It is characterized by deposition of pigment in the retina.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight patients (16 eyes) developed ocular toxicity while undergoing intravenous deferoxamine mesylate (Desferal) chelation therapy for transfusional hemosiderosis." | 3.67 | Deferoxamine (Desferal)-induced toxic retinal pigmentary degeneration and presumed optic neuropathy. ( Jiji, R; Lakhanpal, V; Schocket, SS, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dunaief, JL | 1 |
| Obolensky, A | 1 |
| Berenshtein, E | 1 |
| Lederman, M | 1 |
| Bulvik, B | 1 |
| Alper-Pinus, R | 1 |
| Yaul, R | 1 |
| Deleon, E | 1 |
| Chowers, I | 1 |
| Chevion, M | 1 |
| Banin, E | 1 |
| Lu, M | 1 |
| Hansen, RM | 1 |
| Cunningham, MJ | 1 |
| Eklund, SE | 1 |
| Fulton, AB | 1 |
| Lakhanpal, V | 1 |
| Schocket, SS | 1 |
| Jiji, R | 1 |
| Bournerias, F | 1 |
| Monnier, N | 1 |
| Dufier, JL | 1 |
| Réveillaud, RJ | 1 |
5 other studies available for deferoxamine and Retinitis Pigmentosa
| Article | Year |
|---|---|
Ironing out neurodegeneration: iron chelation for neuroprotection.
Topics: Animals; Chelating Agents; Deferoxamine; Humans; Iron; Organometallic Compounds; Retina; Retinitis P | 2011 |
Zinc-desferrioxamine attenuates retinal degeneration in the rd10 mouse model of retinitis pigmentosa.
Topics: Animals; Biomarkers; Chelating Agents; Cyclic Nucleotide Phosphodiesterases, Type 6; Deferoxamine; D | 2011 |
Effects of desferoxamine on retinal and visual function.
Topics: Adult; beta-Thalassemia; Deferoxamine; Female; Humans; Retina; Retinitis Pigmentosa; Scotoma; Sidero | 2007 |
Deferoxamine (Desferal)-induced toxic retinal pigmentary degeneration and presumed optic neuropathy.
Topics: Aged; Blood Transfusion; Color Perception; Deferoxamine; Female; Hemosiderosis; Humans; Male; Middle | 1984 |
[Severe ocular toxicity of desferrioxamine in the hemodialyzed patient].
Topics: Aged; Aluminum; Deferoxamine; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Retinitis Pigme | 1987 |