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deferoxamine and Primary Peritonitis

deferoxamine has been researched along with Primary Peritonitis in 4 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to determine the effects of vitamin E and the iron chelating agent desferrioxamin (Dfx), supplemented by clindamycin and gentamycin therapy, on peritonitis caused by caecal ligation of a puncture wound in an experimental model."3.71The effects of desferrioxamin and vitamin E as supplements to antibiotics in the treatment of peritonitis in rats. ( Dolay, K; Köksoy, F; Lice, H; Ozşeker, A; Soybir, G; Soybir, N, 2002)
"Hemoglobin (Hb) is a toxic molecule responsible for the extreme lethality associated with experimental Escherichia coli peritonitis, but the mechanism has yet to be elucidated."1.30Hemoglobin toxicity in experimental bacterial peritonitis is due to production of reactive oxygen species. ( Han, JA; Kim, KM; Kim, SS; Kim, YM; Lea, HZ; Yoo, YM, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Soybir, N1
Soybir, G1
Lice, H1
Dolay, K1
Ozşeker, A1
Köksoy, F1
Yoo, YM1
Kim, KM1
Kim, SS1
Han, JA1
Lea, HZ1
Kim, YM1
Lee, JT1
Ahrenholz, DH1
Nelson, RD1
Simmons, RL1
Nakamura, M1
Weil, WB1
Kaufman, DB1

Other Studies

4 other studies available for deferoxamine and Primary Peritonitis

ArticleYear
The effects of desferrioxamin and vitamin E as supplements to antibiotics in the treatment of peritonitis in rats.
    Journal of the Royal College of Surgeons of Edinburgh, 2002, Volume: 47, Issue:5

    Topics: Animals; Clindamycin; Deferoxamine; Drug Therapy, Combination; Gentamicins; Male; Peritonitis; Rats;

2002
Hemoglobin toxicity in experimental bacterial peritonitis is due to production of reactive oxygen species.
    Clinical and diagnostic laboratory immunology, 1999, Volume: 6, Issue:6

    Topics: Animals; Chelating Agents; Cyclic N-Oxides; Deferoxamine; Disease Models, Animal; Edetic Acid; Esche

1999
Mechanisms of the adjuvant effect of hemoglobin in experimental peritonitis. V. The significance of the coordinated iron component.
    Surgery, 1979, Volume: 86, Issue:1

    Topics: Animals; Deferoxamine; Escherichia coli Infections; Ferric Compounds; Hematoporphyrins; Hemin; Hemog

1979
Fatal fungal peritonitis in an adolescent on continuous ambulatory peritoneal dialysis: association with deferoxamine.
    Pediatric nephrology (Berlin, Germany), 1989, Volume: 3, Issue:1

    Topics: Adolescent; Deferoxamine; Glomerulonephritis, Membranous; Humans; Kidney Failure, Chronic; Male; Muc

1989