deferoxamine has been researched along with Pregnancy in 91 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian thalassemic women who received deferoxamine (DFO) inadvertently during early pregnancy." | 7.96 | Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study. ( Brunelli, R; Capone, C; D'Ambrosio, V; Del Negro, V; Giancotti, A; Piccioni, MG; Schiavi, MC; Smacchia, MP; Vena, F, 2020) |
| "N(epsilon)-(Carboxymethyl)lysine (CML), a major product of oxidative modification of glycated proteins, has been suggested to represent a general marker of oxidative stress and long-term damage to proteins in aging, atherosclerosis, and diabetes." | 7.69 | Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. ( Nerlich, AG; Schleicher, ED; Wagner, E, 1997) |
| "In our study, chelation treatment during pregnancy did not prevent the delivery of healthy children." | 5.43 | Iron chelation therapy of transfusion-dependent β-thalassemia during pregnancy in the era of novel drugs: is deferasirox toxic? ( Agapidou, A; Diamantidis, MD; Fotiou, P; Manafas, A; Neokleous, N; Vetsiou, E; Vlachaki, E, 2016) |
| "Iron chelating agents - deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFX) - are used to treat chronic iron overload in patients with β-thalassemia in an attempt to reduce morbidity and mortality related to siderosis." | 4.93 | Clinical monitoring and management of complications related to chelation therapy in patients with β-thalassemia. ( El Rassi, F; Saliba, AN; Taher, AT, 2016) |
| "In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian thalassemic women who received deferoxamine (DFO) inadvertently during early pregnancy." | 3.96 | Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study. ( Brunelli, R; Capone, C; D'Ambrosio, V; Del Negro, V; Giancotti, A; Piccioni, MG; Schiavi, MC; Smacchia, MP; Vena, F, 2020) |
| " The introduction of effective chelation therapy protocols using primarily deferiprone (L1) in combination with deferoxamine (DFO) resulted in the reduction of iron overload induced cardiac failures, which is the main cause of death in thalassemia major." | 3.75 | Advances in the prevention and treatment are changing thalassemia from a fatal to a chronic disease. experience from a Cyprus model and its use as a paradigm for future applications. ( Kolnagou, A; Kontoghiorghes, GJ, 2009) |
| "BeWo cells were incubated with deferoxamine or cobalt chloride under normoxia and hypoxia." | 3.72 | Transcriptional effects of hypoxia on fusiogenic syncytin and its receptor ASCT2 in human cytotrophoblast BeWo cells and in ex vivo perfused placental cotyledons. ( Dötsch, J; Fusch, C; Knerr, I; Linnemann, K; Meissner, U; Rascher, W; Weigel, C, 2003) |
| "N(epsilon)-(Carboxymethyl)lysine (CML), a major product of oxidative modification of glycated proteins, has been suggested to represent a general marker of oxidative stress and long-term damage to proteins in aging, atherosclerosis, and diabetes." | 3.69 | Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. ( Nerlich, AG; Schleicher, ED; Wagner, E, 1997) |
| "An ovine model of maternal iron poisoning in pregnancy was used to examine the placental transport of deferoxamine and ferrioxamine and to follow maternal and fetal serum iron concentrations when maternal serum iron levels exceeded total iron-binding capacity." | 3.68 | An ovine model of maternal iron poisoning in pregnancy. ( Bond, GR; Curry, SC; Raschke, R; Tellez, D; Wiggins, D, 1990) |
| "In our study, chelation treatment during pregnancy did not prevent the delivery of healthy children." | 1.43 | Iron chelation therapy of transfusion-dependent β-thalassemia during pregnancy in the era of novel drugs: is deferasirox toxic? ( Agapidou, A; Diamantidis, MD; Fotiou, P; Manafas, A; Neokleous, N; Vetsiou, E; Vlachaki, E, 2016) |
| "Diabetes insipidus is a rare disorder in pregnant women, predating pregnancy or appearing for the first time during gestation." | 1.36 | Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis. ( Kobielusz-Gembala, I; Krysiak, R; Okopien, B, 2010) |
| "Deferoxamine therapy was continued throughout 2 pregnancies, while in the other it was stopped after 8 weeks: no abnormalities were noted in the children." | 1.31 | High-risk pregnancy in beta-thalassemia major women. Report of three cases. ( De Marzi, CA; Magliari, F; Perniola, R; Rosatelli, MC, 2000) |
| "Deferoxamine was added to the cultures to achieve final concentrations of 200-800 microg/ml, corresponding to in vivo infusion rates of 15-60 mg/kg/h." | 1.31 | Deferoxamine toxicity in hepatoma and primary rat cortical brain cultures. ( Christensen, DW; Kirby, MA; Kisling, R; Thompson, J, 2001) |
| "Preeclampsia is a severe disorder of human pregnancy characterized by generalized activation of maternal endothelial cells." | 1.31 | Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia. ( Burton, GJ; Charnock-Jones, DS; Hung, TH; Skepper, JN, 2002) |
| "The twin-pregnancy was complicated by preeclampsia." | 1.30 | Pregnancy and lactation in homozygous beta-thalassemia major. ( Glanzmann, R; Holzgreve, W; Nars, PW; Surbek, DV, 1998) |
| "Pregnancy was well tolerated by the heart in all women and no endocrinological disorders were observed." | 1.30 | Fertility in thalassemia: the Greek experience. ( Karagiorga-Lagana, M, 1998) |
| "Its use during pregnancy has not been described for either indication." | 1.28 | Whole bowel irrigation during pregnancy. ( Tenenbein, M; Van Ameyde, KJ, 1989) |
| "Successful pregnancy is described in a patient with beta-thalassaemia major, transfusion-dependent from four months of age and treated with desferrioxamine from 13 years of age." | 1.27 | Successful pregnancy in beta-thalassaemia major. ( Martin, K, 1983) |
| "Deferoxamine treatment was given with a delay of 26 hours after ingestion." | 1.27 | Fatal iron intoxication in late pregnancy. ( Biber, B; Dottori, O; Olenmark, M; Rybo, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (30.77) | 18.7374 |
| 1990's | 20 (21.98) | 18.2507 |
| 2000's | 23 (25.27) | 29.6817 |
| 2010's | 18 (19.78) | 24.3611 |
| 2020's | 2 (2.20) | 2.80 |
| Authors | Studies |
|---|---|
| Mielke, N | 1 |
| Johnson, S | 1 |
| Bahl, A | 1 |
| Fadladdin, YAJ | 1 |
| Xue, M | 1 |
| Zhang, X | 1 |
| Chen, J | 1 |
| Liu, F | 1 |
| Xu, J | 1 |
| Xie, J | 1 |
| Yang, Y | 1 |
| Yu, W | 1 |
| Qiu, H | 1 |
| Xue, J | 1 |
| Jiang, J | 1 |
| Liu, Y | 2 |
| Shallom, SJ | 1 |
| Zelazny, AM | 1 |
| Giri, AR | 1 |
| Kaur, N | 1 |
| Yarrarapu, SNS | 1 |
| Rottman Pietrzak, KA | 1 |
| Santos, C | 1 |
| Lowman, PE | 1 |
| Niaz, S | 1 |
| Franco, PM | 1 |
| Sanghavi, DK | 1 |
| Zhu, D | 1 |
| Liang, R | 1 |
| Li, Z | 2 |
| Cheng, L | 1 |
| Ren, J | 1 |
| Guo, Y | 1 |
| Wang, M | 1 |
| Chai, H | 1 |
| Niu, Q | 1 |
| Yang, S | 1 |
| Bai, J | 1 |
| Yu, H | 1 |
| Zhang, H | 1 |
| Qin, X | 1 |
| Sahrakorpi, N | 1 |
| Engberg, E | 1 |
| Stach-Lempinen, B | 1 |
| Tammelin, TH | 1 |
| Kulmala, J | 1 |
| Roine, RP | 1 |
| Koivusalo, SB | 1 |
| Cheng, W | 1 |
| Pang, H | 1 |
| Campen, MJ | 1 |
| Zhang, J | 2 |
| Li, Y | 1 |
| Gao, J | 1 |
| Ren, D | 1 |
| Ji, X | 1 |
| Rothman, N | 1 |
| Lan, Q | 1 |
| Zheng, Y | 1 |
| Leng, S | 1 |
| Hu, Z | 1 |
| Tang, J | 1 |
| Dong, Q | 1 |
| Song, N | 1 |
| Qin, N | 1 |
| Chen, C | 1 |
| Sun, X | 1 |
| Easton, J | 1 |
| Mulder, H | 1 |
| Plyler, E | 1 |
| Neale, G | 1 |
| Walker, E | 1 |
| Li, Q | 1 |
| Ma, X | 1 |
| Chen, X | 1 |
| Huang, IC | 1 |
| Yasui, Y | 1 |
| Ness, KK | 1 |
| Hudson, MM | 1 |
| Robison, LL | 1 |
| Wang, Z | 1 |
| Subota, A | 1 |
| Spotswood, N | 1 |
| Roach, M | 1 |
| Goodarzi, Z | 1 |
| Holroyd-Leduc, J | 1 |
| Park, EA | 1 |
| Graves, SA | 1 |
| Menda, Y | 1 |
| Piccioni, MG | 1 |
| Capone, C | 1 |
| Vena, F | 1 |
| Del Negro, V | 1 |
| Schiavi, MC | 1 |
| D'Ambrosio, V | 1 |
| Giancotti, A | 1 |
| Smacchia, MP | 1 |
| Brunelli, R | 1 |
| Fozza, C | 1 |
| Asara, MA | 1 |
| Vacca, N | 1 |
| Caggiari, S | 1 |
| Monti, A | 1 |
| Zaccheddu, F | 1 |
| Capobianco, G | 1 |
| Dessole, S | 1 |
| Dore, F | 1 |
| Antonucci, R | 1 |
| Chen-Roetling, J | 1 |
| Ma, SK | 1 |
| Cao, Y | 1 |
| Shah, A | 1 |
| Regan, RF | 2 |
| Khdair-Ahmad, F | 1 |
| Aladily, T | 1 |
| Khdair-Ahmad, O | 1 |
| Badran, EF | 1 |
| Kajbafzadeh, AM | 1 |
| Sabetkish, N | 1 |
| Sabetkish, S | 1 |
| Javan-Farazmand, N | 1 |
| Harsini, S | 1 |
| Tavangar, SM | 1 |
| Park, HR | 1 |
| Kamau, PW | 1 |
| Loch-Caruso, R | 1 |
| Schanz, A | 1 |
| Red-Horse, K | 1 |
| Hess, AP | 1 |
| Baston-Büst, DM | 1 |
| Heiss, C | 1 |
| Krüssel, JS | 1 |
| Zhao, MH | 1 |
| Liang, S | 1 |
| Kim, SH | 1 |
| Cui, XS | 1 |
| Kim, NH | 1 |
| Saliba, AN | 1 |
| El Rassi, F | 1 |
| Taher, AT | 1 |
| Diamantidis, MD | 1 |
| Neokleous, N | 1 |
| Agapidou, A | 1 |
| Vetsiou, E | 1 |
| Manafas, A | 1 |
| Fotiou, P | 1 |
| Vlachaki, E | 1 |
| Zhdanov, VV | 1 |
| Udut, EV | 1 |
| Sotnikova, LS | 1 |
| Burmina, YV | 1 |
| Miroshnichenko, LA | 1 |
| Simanina, EV | 1 |
| Polyakova, TY | 1 |
| Zyuz'kov, GN | 1 |
| Chaikovskii, AV | 1 |
| Stavrova, LA | 1 |
| Fedorova, EP | 1 |
| Dygai, AM | 1 |
| Usende, IL | 1 |
| Leitner, DF | 1 |
| Neely, E | 1 |
| Connor, JR | 1 |
| Olopade, JO | 1 |
| Depoix, CL | 1 |
| de Selliers, I | 1 |
| Hubinont, C | 1 |
| Debieve, F | 1 |
| Misumi, S | 1 |
| Kim, TS | 1 |
| Jung, CG | 1 |
| Masuda, T | 1 |
| Urakawa, S | 1 |
| Isobe, Y | 1 |
| Furuyama, F | 1 |
| Nishino, H | 1 |
| Hida, H | 1 |
| Kolnagou, A | 1 |
| Kontoghiorghes, GJ | 1 |
| Messer, JG | 1 |
| Cooney, PT | 1 |
| Kipp, DE | 1 |
| Krysiak, R | 1 |
| Kobielusz-Gembala, I | 1 |
| Okopien, B | 1 |
| Shetty, A | 1 |
| Anwar, SQ | 1 |
| Acharya, S | 1 |
| Chang, TP | 1 |
| Rangan, C | 1 |
| Patel, J | 1 |
| Landers, KA | 1 |
| Mortimer, RH | 1 |
| Richard, K | 1 |
| Hertzberg, BP | 1 |
| Holt, JB | 1 |
| Graff, RD | 1 |
| Gilbert, SR | 1 |
| Dahners, LE | 1 |
| Vaughan, JE | 1 |
| Walsh, SW | 1 |
| Lee, Y | 1 |
| Aono, M | 1 |
| Laskowitz, D | 1 |
| Warner, DS | 1 |
| Pearlstein, RD | 1 |
| Knerr, I | 1 |
| Weigel, C | 1 |
| Linnemann, K | 1 |
| Dötsch, J | 1 |
| Meissner, U | 1 |
| Fusch, C | 1 |
| Rascher, W | 1 |
| Sözen, M | 1 |
| Karaaslan, C | 1 |
| Oner, R | 1 |
| Gümrük, F | 1 |
| Ozdemir, MA | 1 |
| Altay, C | 1 |
| Gürgey, A | 1 |
| Oner, C | 1 |
| Yokoyama, N | 1 |
| Nishikawa, K | 1 |
| Saito, Y | 1 |
| Saito, S | 1 |
| Goto, F | 1 |
| Tsironi, M | 1 |
| Ladis, V | 1 |
| Margellis, Z | 1 |
| Deftereos, S | 1 |
| Kattamis, Ch | 1 |
| Aessopos, A | 1 |
| Madiwale, T | 1 |
| Liebelt, E | 1 |
| Venkat-Raman, N | 1 |
| Venkata-Krishnan, RV | 1 |
| Howarth, ES | 1 |
| Pearson, HA | 1 |
| Baumann, MU | 1 |
| Zamudio, S | 1 |
| Illsley, NP | 1 |
| Asikainen, TM | 1 |
| White, CW | 1 |
| Beneitez, D | 1 |
| Casellas, M | 1 |
| Carrera, A | 1 |
| Duran-Suárez, JR | 1 |
| Baldwin, DA | 1 |
| Jenny, ER | 1 |
| Aisen, P | 1 |
| Blanc, P | 1 |
| Hryhorczuk, D | 1 |
| Danel, I | 1 |
| Pollack, S | 1 |
| Martin, K | 1 |
| Poncz, M | 1 |
| Cohen, A | 1 |
| Schwartz, E | 1 |
| Meadows, K | 1 |
| Rayburn, WF | 1 |
| Donn, SM | 1 |
| Wulf, ME | 1 |
| Dolfin, G | 1 |
| Lumare, A | 1 |
| Tinetti, E | 1 |
| Monetti, C | 1 |
| Jacob, R | 1 |
| Martoglio, G | 1 |
| Matthews, RN | 1 |
| Thomas, RM | 1 |
| Skalicka, AE | 1 |
| Khoury, S | 1 |
| Odeh, M | 1 |
| Oettinger, M | 1 |
| Turk, J | 1 |
| Aks, S | 1 |
| Ampuero, F | 1 |
| Hryhorczuk, DO | 1 |
| Panter, SS | 1 |
| Bosque, MA | 1 |
| Domingo, JL | 1 |
| Corbella, J | 1 |
| Fleckenstein, E | 1 |
| Dirks, W | 1 |
| Dehmel, U | 1 |
| Drexler, HG | 1 |
| Kroos, MJ | 1 |
| Starreveld, JS | 1 |
| Verrijt, CE | 1 |
| van Eijk, HG | 1 |
| van Dijk, JP | 1 |
| Fistarol, M | 1 |
| Zardini, E | 1 |
| Schleicher, ED | 1 |
| Wagner, E | 1 |
| Nerlich, AG | 1 |
| Hubel, CA | 1 |
| Kagan, VE | 1 |
| Kisin, ER | 1 |
| McLaughlin, MK | 1 |
| Roberts, JM | 1 |
| Shilalukey, K | 1 |
| Kaufman, M | 1 |
| Bradley, S | 1 |
| Francombe, WH | 1 |
| Amankwah, K | 1 |
| Goldberg, E | 1 |
| Shear, N | 1 |
| Olivieri, NF | 1 |
| Koren, G | 1 |
| Surbek, DV | 2 |
| Glanzmann, R | 2 |
| Nars, PW | 1 |
| Holzgreve, W | 2 |
| Singer, ST | 1 |
| Vichinsky, EP | 1 |
| Karagiorga-Lagana, M | 1 |
| Perniola, R | 1 |
| Magliari, F | 1 |
| Rosatelli, MC | 1 |
| De Marzi, CA | 1 |
| Tran, T | 1 |
| Wax, JR | 1 |
| Philput, C | 1 |
| Steinfeld, JD | 1 |
| Ingardia, CJ | 1 |
| Pafumi, C | 1 |
| Zizza, G | 1 |
| Caruso, S | 1 |
| Todaro, AM | 1 |
| Pernicone, G | 1 |
| Bandiera, S | 1 |
| Farina, M | 1 |
| Russo, A | 1 |
| Palagiano, A | 1 |
| Pace, L | 1 |
| Christensen, DW | 1 |
| Kisling, R | 1 |
| Thompson, J | 1 |
| Kirby, MA | 1 |
| Hung, TH | 2 |
| Skepper, JN | 2 |
| Burton, GJ | 2 |
| Danzeisen, R | 1 |
| Fosset, C | 1 |
| Chariana, Z | 1 |
| Page, K | 1 |
| David, S | 1 |
| McArdle, HJ | 2 |
| De Marco, CS | 1 |
| Caniggia, I | 1 |
| Charnock-Jones, DS | 1 |
| Rogozin, IA | 1 |
| Rogozina, EK | 1 |
| Mey, U | 1 |
| Finlay, HV | 1 |
| Modell, CB | 1 |
| Strom, RL | 1 |
| Schiller, P | 1 |
| Seeds, AE | 1 |
| Bensel, RT | 1 |
| Forget, BG | 1 |
| Nathan, DG | 1 |
| Lacoste, H | 1 |
| Goyert, GL | 1 |
| Goldman, LS | 1 |
| Wright, DJ | 1 |
| Schwartz, DB | 1 |
| Constable, A | 1 |
| Quick, S | 1 |
| Gray, NK | 1 |
| Hentze, MW | 1 |
| McElhatton, PR | 1 |
| Roberts, JC | 1 |
| Sullivan, FM | 1 |
| Nasr-Esfahani, M | 1 |
| Johnson, MH | 1 |
| Aitken, RJ | 1 |
| Gower, JD | 1 |
| Baldock, RJ | 1 |
| O'Sullivan, AM | 1 |
| Doré, CJ | 1 |
| Coid, CR | 1 |
| Green, CJ | 1 |
| Curry, SC | 1 |
| Bond, GR | 1 |
| Raschke, R | 1 |
| Tellez, D | 1 |
| Wiggins, D | 1 |
| Van Ameyde, KJ | 1 |
| Tenenbein, M | 1 |
| Wong, CT | 1 |
| Morgan, EH | 1 |
| Olenmark, M | 1 |
| Biber, B | 1 |
| Dottori, O | 1 |
| Rybo, G | 1 |
| Ward, MC | 1 |
| Roberts, KR | 1 |
| Babich, JW | 1 |
| Bukhari, MA | 1 |
| Coghlan, G | 1 |
| Westwood, JH | 1 |
| McCready, VR | 1 |
| Ott, RJ | 1 |
| Keberle, H | 1 |
| Schmid, K | 1 |
| Faigle, JW | 1 |
| Fritz, H | 1 |
| Loustalot, P | 1 |
| Chvapil, M | 1 |
| McCarthy, D | 1 |
| Madden, JW | 1 |
| Peacock, EE | 1 |
| Stacher, A | 1 |
| Cartei, G | 1 |
| Barry, M | 1 |
| Verloop, MC | 1 |
| Lauro, V | 1 |
| Giornelli, C | 1 |
| Santilli Giornelli, FE | 1 |
| Fanelli, A | 1 |
| Hofvander, Y | 1 |
| Dallman, PR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of the Cardiovascular Risk Profile of Infants Exposed to Pre-eclampsia in Utero[NCT05091827] | 234 participants (Anticipated) | Observational | 2021-11-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for deferoxamine and Pregnancy
| Article | Year |
|---|---|
Topics: Adult; Aging; Aluminum; Alzheimer Disease; Animals; Anti-Bacterial Agents; Artemisia annua; Body Mas | 2022 |
Clinical monitoring and management of complications related to chelation therapy in patients with β-thalassemia.
Topics: Benzoates; beta-Thalassemia; Chelation Therapy; Deferasirox; Deferiprone; Deferoxamine; Disease Mana | 2016 |
Iron poisoning: a literature-based review of epidemiology, diagnosis, and management.
Topics: Animals; Chemistry, Pharmaceutical; Child; Deferoxamine; Drug Packaging; Female; Humans; Iron; Magne | 2011 |
Iron: not a benign therapeutic drug.
Topics: Chelation Therapy; Child; Deferoxamine; Female; Humans; Iron; Liver; Poisoning; Pregnancy; Pregnancy | 2006 |
Intentional iron overdose in pregnancy--management and outcome.
Topics: Adolescent; Adult; Analysis of Variance; Chelating Agents; Deferoxamine; Drug Overdose; Emergency Se | 2000 |
[Foundations of the diagnosis and therapy of hemolytic anemias].
Topics: Agglutinins; Anemia, Hemolytic; Antigens; Autoimmune Diseases; Blood Protein Disorders; Blood Transf | 1978 |
Thalassemia.
Topics: Blood Transfusion; Bone Marrow Examination; Deferoxamine; Diagnosis, Differential; Erythrocyte Count | 1975 |
Acute iron intoxication in pregnancy: case report and review of the literature.
Topics: Adolescent; Deferoxamine; Delayed-Action Preparations; Female; Ferrous Compounds; Humans; Poisoning; | 1992 |
[Diseases caused by iron metabolism disorders and their therapy].
Topics: Adult; Anemia, Hypochromic; Anti-Glomerular Basement Membrane Disease; Bloodletting; Deferoxamine; D | 1969 |
1 trial available for deferoxamine and Pregnancy
| Article | Year |
|---|---|
[Comparison of the effects of colloid and crystalloid solution for volume preloading on maternal hemodynamics and neonatal outcome in spinal anesthesia for cesarean section].
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Colloids; Crystalloid Solution | 2004 |
81 other studies available for deferoxamine and Pregnancy
| Article | Year |
|---|---|
Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study.
Topics: Adult; beta-Thalassemia; Chelation Therapy; Deferoxamine; Female; Humans; Live Birth; Maternal Expos | 2020 |
Pregnancy Outcome among Women with Beta-Thalassemia Major in North Sardinia.
Topics: Abortion, Spontaneous; Adult; Benzoates; beta-Thalassemia; Deferasirox; Deferoxamine; Diabetes, Gest | 2017 |
Hemopexin increases the neurotoxicity of hemoglobin when haptoglobin is absent.
Topics: Animals; Antidotes; Cyclohexylamines; Deferoxamine; Female; Ferritins; Globins; Haptoglobins; Heme O | 2018 |
Chelation therapy for secondary neonatal iron over load: Lessons learned from rhesus hemolytic disease.
Topics: Blood Transfusion; Chelation Therapy; Cholestasis; Deferoxamine; Erythroblastosis, Fetal; Female; Fe | 2018 |
The ameliorative effect of various antioxidants on Adriamycin-induced fetal renal abnormalities.
Topics: Amifostine; Animals; Antibiotics, Antineoplastic; Antioxidants; Deferoxamine; Disease Models, Animal | 2013 |
Involvement of reactive oxygen species in brominated diphenyl ether-47-induced inflammatory cytokine release from human extravillous trophoblasts in vitro.
Topics: alpha-Tocopherol; Antioxidants; Cell Line; Cell Survival; Cyclic N-Oxides; Cytokines; Deferoxamine; | 2014 |
Oxygen regulates human cytotrophoblast migration by controlling chemokine and receptor expression.
Topics: Cell Movement; Chemokines; Deferoxamine; Female; Gene Expression; Humans; Oxygen; Placentation; Preg | 2014 |
Fe(III) Is Essential for Porcine Embryonic Development via Mitochondrial Function Maintenance.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Blastocyst; Cells, Cultured; Cytochromes c; Deferoxamine | 2015 |
Iron chelation therapy of transfusion-dependent β-thalassemia during pregnancy in the era of novel drugs: is deferasirox toxic?
Topics: Adult; Benzoates; beta-Thalassemia; Chelation Therapy; Deferasirox; Deferiprone; Deferoxamine; Femal | 2016 |
Pathogenetic Evaluation of Dysfunction in the Erythron System of Experimental Animals during Modeling of Iron Deficiency Anemia in the Gestation Period.
Topics: Anemia, Iron-Deficiency; Animals; Blood Cell Count; Bone Marrow; Deferoxamine; Erythrocytes; Erythro | 2016 |
The Deterioration Seen in Myelin Related Morphophysiology in Vanadium Exposed Rats is Partially Protected by Concurrent Iron Deficiency.
Topics: Anemia, Iron-Deficiency; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Deferoxamine; Femal | 2016 |
HIF1A and EPAS1 potentiate hypoxia-induced upregulation of inhibin alpha chain expression in human term cytotrophoblasts in vitro.
Topics: Amino Acids, Dicarboxylic; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell | 2017 |
Enhanced neurogenesis from neural progenitor cells with G1/S-phase cell cycle arrest is mediated by transforming growth factor beta1.
Topics: Animals; Aphidicolin; Cell Differentiation; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinase Inhib | 2008 |
Advances in the prevention and treatment are changing thalassemia from a fatal to a chronic disease. experience from a Cyprus model and its use as a paradigm for future applications.
Topics: Chelation Therapy; Chronic Disease; Cyprus; Deferiprone; Deferoxamine; Female; Ferritins; Genetic Te | 2009 |
Iron chelator deferoxamine alters iron-regulatory genes and proteins and suppresses osteoblast phenotype in fetal rat calvaria cells.
Topics: Alkaline Phosphatase; Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Deferoxamin | 2010 |
Recurrent pregnancy-induced diabetes insipidus in a woman with hemochromatosis.
Topics: Adult; Biopsy, Needle; Cystinyl Aminopeptidase; Deferoxamine; Diabetes Insipidus; Female; Hemochroma | 2010 |
Aplastic anaemia in pregnancy.
Topics: Anemia, Aplastic; Combined Modality Therapy; Deferoxamine; Female; Humans; Platelet Transfusion; Pre | 2011 |
Expression and uptake of the thyroxine-binding protein transthyretin is regulated by oxygen in primary trophoblast placental cells.
Topics: Adult; Brefeldin A; Cell Hypoxia; Cell Line; Cells, Cultured; Deferoxamine; Enzyme Inhibitors; Femal | 2012 |
An evaluation of carrier agents for desferoxamine, an up-regulator of vascular endothelial growth factor.
Topics: Animals; Biocompatible Materials; Bone Matrix; Calcium Sulfate; Collagen; Deferoxamine; Drug Carrier | 2013 |
Oxidative stress reproduces placental abnormalities of preeclampsia.
Topics: Adult; Analysis of Variance; Catalase; Cell Line; Chorionic Gonadotropin; Deferoxamine; Female; Ferr | 2002 |
Apolipoprotein E protects against oxidative stress in mixed neuronal-glial cell cultures by reducing glutamate toxicity.
Topics: Animals; Apolipoproteins E; Bicarbonates; Cells, Cultured; Deferoxamine; Dizocilpine Maleate; Dose-R | 2004 |
Transcriptional effects of hypoxia on fusiogenic syncytin and its receptor ASCT2 in human cytotrophoblast BeWo cells and in ex vivo perfused placental cotyledons.
Topics: Amino Acid Transport System ASC; Cell Line; Cobalt; Computer Systems; Deferoxamine; Down-Regulation; | 2003 |
Severe hemolytic anemia associated with Hb Volga [beta27(B9)Ala-->Asp]: GCC-->GAC at codon 27 in a Turkish family.
Topics: Adult; Anemia, Hemolytic, Congenital; Blood Protein Electrophoresis; Child, Preschool; Codon; Combin | 2004 |
Impairment of cardiac function in a successful full-term pregnancy in a homozygous beta-thalassemia major: does chelation have a positive role?
Topics: Adult; beta-Thalassemia; Deferoxamine; Female; Heart Diseases; Humans; Iron Chelating Agents; Pregna | 2005 |
Successful pregnancy outcome following maternal intravenous immunoglobulin treatment in a woman with recurrent perinatal haemochromatosis.
Topics: Acetylcysteine; Adult; Deferoxamine; Diagnosis, Differential; Female; Ferritins; Fetal Diseases; Fre | 2006 |
Iron studies in infants born to an iron overloaded mother with beta-thalassemia major: possible effects of maternal desferrioxamine therapy.
Topics: Adult; beta-Thalassemia; Deferoxamine; Female; Fetal Blood; Humans; Infant, Newborn; Injections, Sub | 2007 |
Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1.
Topics: Actins; Cell Hypoxia; Cell Line, Tumor; Choriocarcinoma; Chorionic Villi; Cobalt; Cysteine Proteinas | 2007 |
HIF stabilizing agents: shotgun or scalpel?
Topics: Amino Acids, Dicarboxylic; Animals; Cobalt; Deferoxamine; Female; Humans; Hypoxia-Inducible Factor 1 | 2007 |
[Beta-thalassemia major and pregnancy to term].
Topics: Adult; beta-Thalassemia; Deferoxamine; Female; Follow-Up Studies; Humans; Pregnancy; Pregnancy Compl | 2008 |
The effect of human serum transferrin and milk lactoferrin on hydroxyl radical formation from superoxide and hydrogen peroxide.
Topics: Apoproteins; Deferoxamine; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Humans; Hydr | 1984 |
Deferoxamine treatment of acute iron intoxication in pregnancy.
Topics: Abortion, Induced; Adolescent; Deferoxamine; Female; Ferric Compounds; Humans; Ipecac; Iron; Pregnan | 1984 |
Malaria and iron.
Topics: Deferoxamine; Female; Heme; Humans; Iron Deficiencies; Malaria; Plasmodium; Plasmodium falciparum; P | 1983 |
Successful pregnancy in beta-thalassaemia major.
Topics: Adult; Blood Transfusion; Deferoxamine; Female; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infa | 1983 |
Thalassemia.
Topics: Blood Transfusion; Chromosome Deletion; Deferoxamine; DNA; Erythrocyte Transfusion; Female; Gene Exp | 1984 |
A successful pregnancy outcome in transfusion dependent thalassaemia major.
Topics: Adult; Blood Transfusion; Deferoxamine; Erythrocyte Transfusion; Female; Humans; Infant, Newborn; Ma | 1984 |
Iron overdose during pregnancy: successful therapy with deferoxamine.
Topics: Adult; Deferoxamine; Female; Ferrous Compounds; Humans; Iron; Pregnancy; Suicide, Attempted | 1983 |
[Obstetrical and hematological problems in a pregnant woman with intermediate beta-thalassemia].
Topics: Adult; Blood Transfusion; Deferoxamine; Female; Humans; Pregnancy; Pregnancy Complications, Hematolo | 1983 |
Advances in the management of homozygous beta-thalassaemia, including desferrioxamine infusion therapy and prenatal diagnosis.
Topics: Blood Transfusion; Deferoxamine; Female; Fetal Blood; Fetal Diseases; Globins; Humans; Pregnancy; Pr | 1980 |
Successful pregnancy in transfusion-dependent thalassaemia.
Topics: Adult; Blood Transfusion; Deferoxamine; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Compli | 1980 |
Deferoxamine treatment for acute iron intoxication in pregnancy.
Topics: Adult; Antidotes; Deferoxamine; Female; Ferrous Compounds; Humans; Injections, Intravenous; Iron; Pr | 1995 |
Successful therapy of iron intoxication in pregnancy with intravenous deferoxamine and whole bowel irrigation.
Topics: Adult; Deferoxamine; Female; Humans; Infusions, Intravenous; Intestines; Iron; Pregnancy; Pregnancy | 1993 |
Neurotoxicity of hemoglobin in cortical cell culture.
Topics: Animals; Antioxidants; Cell Death; Cells, Cultured; Cerebral Cortex; Chromans; Culture Media; Defero | 1993 |
Assessment of the developmental toxicity of deferoxamine in mice.
Topics: Animals; Body Weight; Deferoxamine; Eating; Embryonic and Fetal Development; Female; Gestational Age | 1995 |
Cloning and characterization of the human tartrate-resistant acid phosphatase (TRAP) gene.
Topics: Acid Phosphatase; Animals; Base Sequence; Biomarkers, Tumor; Blotting, Northern; Cell Line; Cloning, | 1996 |
Regulation of transferrin receptor synthesis by human cytotrophoblast cells in culture.
Topics: Cells, Cultured; Deferoxamine; Female; Ferric Compounds; Humans; Pregnancy; Quaternary Ammonium Comp | 1996 |
[Beta-thalassemia and pregnancy: 2 rare cases].
Topics: beta-Thalassemia; Bone Marrow Transplantation; Cardiotocography; Cesarean Section; Combined Modality | 1996 |
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Ch | 1997 |
Increased ascorbate radical formation and ascorbate depletion in plasma from women with preeclampsia: implications for oxidative stress.
Topics: Adult; Ascorbic Acid; Chromatography, High Pressure Liquid; Deferoxamine; Electron Spin Resonance Sp | 1997 |
Counseling sexually active teenagers treated with potential human teratogens.
Topics: Adolescent; Adolescent Behavior; Anemia, Sickle Cell; beta-Thalassemia; Contraception Behavior; Coun | 1997 |
Pregnancy and lactation in homozygous beta-thalassemia major.
Topics: Adult; beta-Thalassemia; Breast Feeding; Chelating Agents; Deferoxamine; Female; Homozygote; Humans; | 1998 |
Deferoxamine treatment during pregnancy: is it harmful?
Topics: Abnormalities, Drug-Induced; Adult; Chelating Agents; Deferoxamine; Female; Humans; Pregnancy; Pregn | 1999 |
Fertility in thalassemia: the Greek experience.
Topics: Adult; beta-Thalassemia; Cesarean Section; Chelating Agents; Deferoxamine; Endocrine Glands; Female; | 1998 |
Pregnancy and homozygous beta thalassemia major.
Topics: beta-Thalassemia; Breast Feeding; Chelating Agents; Deferoxamine; Female; Humans; Infant, Newborn; P | 1999 |
High-risk pregnancy in beta-thalassemia major women. Report of three cases.
Topics: Adult; Aspirin; beta-Thalassemia; Cardiomyopathy, Dilated; Deferoxamine; Female; Humans; Pregnancy; | 2000 |
Pregnancy outcome of a transfusion-dependent thalassemic woman.
Topics: Blood Transfusion; Chelating Agents; Deferoxamine; Female; Ferritins; Humans; Pregnancy; Pregnancy C | 2000 |
[Pregnancy in women with thalassaemia].
Topics: Adult; Blood Transfusion; Chelating Agents; Deferoxamine; Female; Folic Acid; Hematinics; Humans; In | 2001 |
Deferoxamine toxicity in hepatoma and primary rat cortical brain cultures.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Survival; Cerebral Cortex; Deferox | 2001 |
In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.
Topics: Aldehydes; Cyclic N-Oxides; Deferoxamine; Female; Fluorescent Antibody Technique; Heat-Shock Protein | 2001 |
Placental ceruloplasmin homolog is regulated by iron and copper and is implicated in iron metabolism.
Topics: Animals; Cell Fractionation; Ceruloplasmin; Choriocarcinoma; Copper; Deferoxamine; Female; Heterocyc | 2002 |
Mechanisms of oxygen sensing in human trophoblast cells.
Topics: Adult; Chorionic Villi; Cobalt; Deferoxamine; Drug Combinations; Enzyme Inhibitors; Female; Ferrous | 2002 |
Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia.
Topics: Apoptosis; Caspase 3; Caspases; Cell Hypoxia; Cell Nucleus; Chorionic Villi; Culture Techniques; Cyt | 2002 |
[Change in the level of reserve iron in normal pregnancy].
Topics: Deferoxamine; Female; Humans; Iron; Postpartum Period; Pregnancy; Pregnancy Trimester, Second; Pregn | 1978 |
Phenistix urine test-strip and desferioxamine.
Topics: Deferoxamine; Diagnostic Errors; Female; Humans; Infant; Methods; Pregnancy; Twins; Urine | 1978 |
Practical approaches to the control of thalassaemia.
Topics: Blood Transfusion; Deferoxamine; Female; Genetic Counseling; Humans; Male; Pregnancy; Prenatal Diagn | 1976 |
Fatal iron poisoning in a pregnant female.
Topics: Acute Disease; Adolescent; Deferoxamine; Female; Gastrointestinal Hemorrhage; Humans; Iron; Liver; P | 1976 |
Modulation of the RNA-binding activity of a regulatory protein by iron in vitro: switching between enzymatic and genetic function?
Topics: Base Sequence; Chromatography, Affinity; Cysteine; Deferoxamine; Female; Humans; Iron; Iron-Regulato | 1992 |
The consequences of iron overdose and its treatment with desferrioxamine in pregnancy.
Topics: Birth Weight; Deferoxamine; Drug Overdose; Female; Humans; Infant, Newborn; Iron; Male; Pregnancy; P | 1991 |
The effect of iron and iron chelators on the in-vitro block to development of the mouse preimplantation embryo: BAT6 a new medium for improved culture of mouse embryos in vitro.
Topics: Animals; Apoproteins; Ascorbic Acid; Cell Division; Culture Media; Culture Techniques; Deferoxamine; | 1990 |
Protection against endotoxin-induced foetal resorption in mice by desferrioxamine and ebselen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Azoles; Deferoxamine; Dose-Response | 1990 |
An ovine model of maternal iron poisoning in pregnancy.
Topics: Animals; Blood Pressure; Body Weight; Deferoxamine; Disease Models, Animal; Female; Ferric Compounds | 1990 |
Whole bowel irrigation during pregnancy.
Topics: Adolescent; Deferoxamine; Digestive System; Female; Humans; Iron; Pregnancy; Pregnancy Complications | 1989 |
Effect of iron chelators on placental uptake and transfer of iron in rat.
Topics: 2,2'-Dipyridyl; Animals; Deferoxamine; Female; Iron; Iron Chelating Agents; Osmolar Concentration; P | 1987 |
Fatal iron intoxication in late pregnancy.
Topics: Adult; Cesarean Section; Deferoxamine; Delayed-Action Preparations; Female; Ferrous Compounds; Human | 1987 |
An antibody-desferrioxamine conjugate labelled with 67Ga.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Deferoxamine; Female; Gallium Radioisotop | 1986 |
[On the penetration of foreign body materials into the young vertebrate embryo].
Topics: Animals; Deferoxamine; Embryo Implantation; Embryo, Mammalian; Female; Glycosaminoglycans; Lipids; P | 1966 |
Effect of 1,10-phenanthroline and desferrioxamine in vivo on prolyl hydroxylase and hydroxylation of collagen in various tissues of rats.
Topics: Animals; Animals, Newborn; Body Weight; Calcium; Carrageenan; Collagen; Deferoxamine; Estradiol; Fem | 1974 |
[A case of acute poisoning caused by ferrous fumarate. (Anatomo-clinical, physiopathological and therapeutic findings)].
Topics: Acute Disease; Adult; Deferoxamine; Digestive System; Edetic Acid; Female; Fumarates; Gastric Lavage | 1969 |
Iron depletion without anemia: a controversial subject.
Topics: Adolescent; Adult; Anemia, Hypochromic; Bone Marrow; Child; Child, Preschool; Deferoxamine; Diet; Fe | 1970 |
[Effects of iron-chelating agents on pregnancy in the rat. Experimental findings].
Topics: Abortion, Spontaneous; Animals; Deferoxamine; Extraembryonic Membranes; Female; Fetus; Pregnancy; Pr | 1968 |
Hematological investigations in Ethiopia with special reference to a high iron intake.
Topics: Adolescent; Adult; Altitude; Anemia; Autopsy; Blood Sedimentation; Blood Specimen Collection; Body W | 1968 |
Iron restriction in the nursing rat: early effects upon tissue heme proteins, hemoglobin and liver iron.
Topics: Animals; Animals, Newborn; Brain; Cell Differentiation; Cytochromes; Deferoxamine; Deficiency Diseas | 1969 |