deferoxamine has been researched along with Pre-Eclampsia in 3 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preeclampsia is a severe disorder of human pregnancy characterized by generalized activation of maternal endothelial cells." | 1.31 | Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia. ( Burton, GJ; Charnock-Jones, DS; Hung, TH; Skepper, JN, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vaughan, JE | 1 |
| Walsh, SW | 1 |
| Hubel, CA | 1 |
| Kagan, VE | 1 |
| Kisin, ER | 1 |
| McLaughlin, MK | 1 |
| Roberts, JM | 1 |
| Hung, TH | 1 |
| Skepper, JN | 1 |
| Charnock-Jones, DS | 1 |
| Burton, GJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of the Cardiovascular Risk Profile of Infants Exposed to Pre-eclampsia in Utero[NCT05091827] | 234 participants (Anticipated) | Observational | 2021-11-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for deferoxamine and Pre-Eclampsia
| Article | Year |
|---|---|
Oxidative stress reproduces placental abnormalities of preeclampsia.
Topics: Adult; Analysis of Variance; Catalase; Cell Line; Chorionic Gonadotropin; Deferoxamine; Female; Ferr | 2002 |
Increased ascorbate radical formation and ascorbate depletion in plasma from women with preeclampsia: implications for oxidative stress.
Topics: Adult; Ascorbic Acid; Chromatography, High Pressure Liquid; Deferoxamine; Electron Spin Resonance Sp | 1997 |
Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia.
Topics: Apoptosis; Caspase 3; Caspases; Cell Hypoxia; Cell Nucleus; Chorionic Villi; Culture Techniques; Cyt | 2002 |