deferoxamine has been researched along with Porphyria in 54 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of the present work is to investigate the ability of desferrioxamine (DF) as an iron chelator to revert or decrease a severe experimental porphyria induced by hexachlorobenzene (HCB) in rats; DF treatment started after 17 weeks of HCB intoxication and was continued until the 27th week." | 7.67 | [Evaluation of deferoxamine capacity to revert a severe porphyria induced by hexachlorobenzene]. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R, 1987) |
| "The effect of desferrioxamine on hexachlorobenzene (HCB)-induced porphyria was studied in female rats in order to investigate the role of iron in the development of this porphyria." | 7.67 | Effect of an iron chelator on the onset of hexachlorobenzene-induced porphyria in rats. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R, 1986) |
| "The present work deals with the effect of desferrioxamine (DF) on hexachlorobenzene (HCB)-induced porphyria in female rats with the purpose of further investigation of the role of iron in the development of this porphyria." | 7.67 | Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstock de Calmanovici, R, 1986) |
| "Porphyria was induced in vivo in mice using 3,5-diethoxycarbonyl-1,4-dihydrocollidine or in vitro by exposing human liver Huh7 cells and keratinocytes, or their lysates, to protoporphyrin-IX, other porphyrins, or to δ-aminolevulinic acid plus deferoxamine." | 3.91 | Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells. ( Basrur, V; Carter, EL; Herrmann, H; Lehnert, N; Maitra, D; Nesvizhskii, AI; Omary, MB; Osawa, Y; Ragsdale, SW; Richardson, R; Rittié, L; Wolf, MW; Zhang, H, 2019) |
| "The purpose of the present work is to investigate the ability of desferrioxamine (DF) as an iron chelator to revert or decrease a severe experimental porphyria induced by hexachlorobenzene (HCB) in rats; DF treatment started after 17 weeks of HCB intoxication and was continued until the 27th week." | 3.67 | [Evaluation of deferoxamine capacity to revert a severe porphyria induced by hexachlorobenzene]. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R, 1987) |
| "The effect of desferrioxamine on hexachlorobenzene (HCB)-induced porphyria was studied in female rats in order to investigate the role of iron in the development of this porphyria." | 3.67 | Effect of an iron chelator on the onset of hexachlorobenzene-induced porphyria in rats. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstok de Calmanovici, R, 1986) |
| "The present work deals with the effect of desferrioxamine (DF) on hexachlorobenzene (HCB)-induced porphyria in female rats with the purpose of further investigation of the role of iron in the development of this porphyria." | 3.67 | Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria. ( Aldonatti, CA; Billi, SC; San Martín de Viale, LC; Wainstock de Calmanovici, R, 1986) |
| "Hemochromatosis is a syndrome which, when fully expressed, is manifested by melanoderma , diabetes mellitus, and liver cirrhosis, with iron overload involving parenchymal and reticuloendothelial cells in many organ systems." | 2.36 | Iron overload disorders: natural history, pathogenesis, diagnosis, and therapy. ( Kellermeyer, RW; McLaren, GD; Muir, WA, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (83.33) | 18.7374 |
| 1990's | 8 (14.81) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (1.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maitra, D | 1 |
| Carter, EL | 1 |
| Richardson, R | 1 |
| Rittié, L | 1 |
| Basrur, V | 1 |
| Zhang, H | 1 |
| Nesvizhskii, AI | 1 |
| Osawa, Y | 1 |
| Wolf, MW | 1 |
| Ragsdale, SW | 1 |
| Lehnert, N | 1 |
| Herrmann, H | 1 |
| Omary, MB | 1 |
| HOLZMANN, H | 1 |
| SAUNDERS, SJ | 1 |
| VENTURA, S | 1 |
| COLI, L | 1 |
| WOEHLER, F | 1 |
| Beurey, J | 2 |
| Weber, M | 2 |
| Montet, Y | 1 |
| Jeandidier, P | 1 |
| Barbier, JM | 1 |
| McLaren, GD | 1 |
| Muir, WA | 1 |
| Kellermeyer, RW | 1 |
| Marchesi, L | 1 |
| Di Padova, C | 1 |
| Cainelli, T | 1 |
| Reseghetti, A | 1 |
| Di Padova, F | 1 |
| Rovagnati, P | 1 |
| Cantoni, L | 1 |
| Gibertini, P | 4 |
| Rocchi, E | 6 |
| Cassanelli, M | 6 |
| Pietrangelo, A | 4 |
| Ventura, E | 6 |
| Halliday, JW | 1 |
| Bassett, ML | 1 |
| Lim, LK | 1 |
| Srivastava, G | 1 |
| Brooker, JD | 1 |
| May, BK | 1 |
| Elliott, WH | 1 |
| van Gelder, W | 1 |
| Siersema, PD | 1 |
| Voogd, A | 1 |
| de Jeu-Jaspars, NC | 1 |
| van Eijk, HG | 2 |
| Koster, JF | 1 |
| de Rooy, FW | 1 |
| Wilson, JH | 1 |
| Hahn, M | 1 |
| Gildemeister, OS | 1 |
| Krauss, GL | 1 |
| Pepe, JA | 1 |
| Lambrecht, RW | 2 |
| Donohue, S | 1 |
| Bonkovsky, HL | 2 |
| Kautzsch, E | 1 |
| Piazza, V | 1 |
| Villa, G | 1 |
| Galli, F | 1 |
| Segagni, S | 1 |
| Bovio, G | 1 |
| Poggio, F | 1 |
| Picardi, L | 1 |
| Bianco, L | 1 |
| Salvadeo, A | 1 |
| Barosi, G | 1 |
| Toriyama, T | 1 |
| Kawahara, H | 1 |
| Cable, EE | 1 |
| Cable, JW | 1 |
| Donohue, SE | 1 |
| White, EC | 1 |
| Greene, YJ | 1 |
| Srivastava, KK | 1 |
| Arnold, WN | 1 |
| Borghi, A | 3 |
| Paolillo, F | 1 |
| Pradelli, M | 1 |
| Pellizzardi, S | 1 |
| Vezzosi, A | 1 |
| Gallo, E | 2 |
| Baccarani Contri, M | 1 |
| Stockenhuber, F | 1 |
| Kurz, R | 1 |
| Grimm, G | 1 |
| Moser, G | 1 |
| Balcke, P | 1 |
| Muñoz, JJ | 1 |
| Garcia-Cabezas, J | 1 |
| Martinez-Verano, J | 1 |
| Perez-Oteyza, C | 1 |
| Enriquez de Salamanca, R | 2 |
| De Matteis, F | 1 |
| Harvey, C | 1 |
| Reed, C | 1 |
| Hempenius, R | 1 |
| Wainstok de Calmanovici, R | 2 |
| Billi, SC | 3 |
| Aldonatti, CA | 3 |
| San Martín de Viale, LC | 3 |
| Pantaleoni, M | 1 |
| Jensen, J | 1 |
| Wainstock de Calmanovici, R | 1 |
| Praga, M | 1 |
| Andres, A | 1 |
| Nieto, J | 1 |
| Oliet, A | 1 |
| Perpiña, J | 1 |
| Morales, JM | 1 |
| Bobeck-Rutsaert, MM | 1 |
| Wiltink, WF | 1 |
| den Kelder M, OP | 1 |
| Leijnse, B | 1 |
| Cumming, RL | 1 |
| Goldberg, A | 1 |
| Morrow, J | 1 |
| Smith, JA | 1 |
| Gheorghiu, G | 1 |
| Forsea, D | 1 |
| Nozicková, M | 2 |
| Storck, H | 1 |
| Schwarz, K | 1 |
| Ott, F | 1 |
| Dyerberg, J | 1 |
| Turnbull, A | 1 |
| Thivolet, J | 3 |
| Bondet, P | 2 |
| Perrot, H | 3 |
| Moene, Y | 2 |
| Mallein, R | 1 |
| Sabater, P | 1 |
| Burg, G | 2 |
| Wöhler, F | 1 |
| Taxay, EP | 1 |
| Taljaard, JJ | 1 |
| Shanley, BC | 1 |
| Stewart-Wynne, EG | 1 |
| Deppe, WM | 1 |
| Joubert, SM | 1 |
| Haneke, E | 1 |
| Schwartze, G | 1 |
| Horvat, Z | 1 |
| Bakran, I | 1 |
| Radosević, Z | 1 |
| Votruba, M | 1 |
| Pazderka, J | 1 |
| Bianco, G | 2 |
| Ramello, A | 1 |
| Ricco, G | 1 |
| Matone, S | 1 |
| Walsh, JR | 1 |
| Lobitz, WC | 1 |
| Mahler, DJ | 1 |
| Kingery, FA | 1 |
| Barth, J | 1 |
| Petter, O | 1 |
| Amerio, PL | 1 |
| Garcovich, A | 1 |
| Ormea, F | 1 |
| Gurecki, H | 1 |
| Perello, R | 1 |
| Vadot, J | 1 |
| Schnack, H | 1 |
| Wewalka, F | 1 |
| Mazza, U | 1 |
| Fiorina, L | 1 |
| Prato, V | 1 |
3 reviews available for deferoxamine and Porphyria
| Article | Year |
|---|---|
Iron overload disorders: natural history, pathogenesis, diagnosis, and therapy.
Topics: Anemia, Hypochromic; Biological Transport; Bloodletting; Chelating Agents; Deferoxamine; Disease Mod | 1983 |
[Deferoxamine-B, a ferriuretic chelate].
Topics: Anemia, Hypochromic; Chemical Phenomena; Chemistry; Deferoxamine; Hemochromatosis; Hemosiderosis; Hu | 1967 |
Iron metabolism in the porphyrias.
Topics: Alcohol Drinking; Amino Acids; Anemia, Hemolytic; Bloodletting; Bone Marrow; Bone Marrow Diseases; D | 1971 |
1 trial available for deferoxamine and Porphyria
| Article | Year |
|---|---|
A comparative trial of desferrioxamine and hydroxychloroquine for treatment of porphyria cutanea tarda in alcoholic patients.
Topics: Adult; Alcoholism; Clinical Trials as Topic; Deferoxamine; Ferritins; Humans; Hydroxychloroquine; Ir | 1984 |
50 other studies available for deferoxamine and Porphyria
| Article | Year |
|---|---|
Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cell Line; Deferoxamine; Heme; Hepatocytes; | 2019 |
[On the use of desferrioxamine in porphyria cutanea tarda].
Topics: Animals; Chelating Agents; Deferoxamine; Humans; Hydroxamic Acids; Porifera; Porphyria Cutanea Tarda | 1963 |
IRON METABOLISM IN SYMPTOMATIC PORPHYRIA. A PRELIMINARY COMMUNICATION.
Topics: Alcoholism; Blood Chemical Analysis; Chelating Agents; Deferoxamine; Feces; Hemochromatosis; Hexachl | 1963 |
[RESEARCH ON DESFERRIOXAMINE B. 3. THE CLINICAL USE OF DESFERRIOXAMINE B].
Topics: Anemia; Anemia, Hemolytic; Anemia, Macrocytic; Deferoxamine; Hematologic Diseases; Hemochromatosis; | 1964 |
[TREATMENT OF HEMOCHROMATOSIS].
Topics: Deferoxamine; Drug Therapy; Hemochromatosis; Hemosiderosis; Humans; Porphyrias; Thalassemia | 1965 |
[Porphyria cutanea tarda with hypersideremia: effectiveness of desferrioxamine (Desferal)].
Topics: Deferoxamine; Diagnosis, Differential; Hemochromatosis; Humans; Iron; Male; Middle Aged; Porphyrias | 1966 |
Porphyria cutanea tarda in beta-thalassemia trait carriers.
Topics: Adult; Deferoxamine; Heterozygote; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Skin Disea | 1984 |
Advances in the treatment of porphyria cutanea tarda. Effectiveness of slow subcutaneous desferrioxamine infusion.
Topics: Adult; Aged; Deferoxamine; Humans; Infusions, Parenteral; Injections, Subcutaneous; Middle Aged; Por | 1984 |
Treatment of iron storage disorders.
Topics: Anemia; Deferoxamine; Hemochromatosis; Humans; Iron; Liver Cirrhosis; Porphyrias; Skin Diseases; Tha | 1980 |
Evidence that in chick embryos destruction of hepatic microsomal cytochrome P-450 haem is a general mechanism of induction of delta-aminolaevulinate synthase by porphyria-causing drugs.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Cytochrome P-450 Enzym | 1980 |
The effect of desferrioxamine on iron metabolism and lipid peroxidation in hepatocytes of C57BL/10 mice in experimental uroporphyria.
Topics: Animals; Deferoxamine; Iron; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C5 | 1993 |
Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: potential implications for patients with acute porphyria.
Topics: Animals; Cells, Cultured; Chick Embryo; Deferoxamine; Dose-Response Relationship, Drug; Liver; Pheno | 1997 |
[Letter: Therapy of hemochromatosis].
Topics: Bloodletting; Deferoxamine; Hemochromatosis; Humans; Porphyrias; Siderosis | 1975 |
Erythropoietin as treatment of haemodialysis-related porphyria cutanea tarda.
Topics: Aged; Deferoxamine; Erythrocytes; Erythropoietin; Humans; Iron; Male; Porphyrias; Porphyrins; Protop | 1992 |
[Small volume plasma exchange therapy in patients with porphyria cutanea tarda on maintenance hemodialysis].
Topics: Deferoxamine; Erythropoietin; Humans; Kidney Diseases; Male; Middle Aged; Plasma Exchange; Porphyria | 1992 |
Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh).
Topics: 5-Aminolevulinate Synthetase; Alcoholic Beverages; Animals; Bicyclic Monoterpenes; Camphor; Cells, C | 1992 |
Liver iron overload and desferrioxamine treatment of porphyria cutanea tarda.
Topics: Bloodletting; Chromatography, High Pressure Liquid; Chronic Disease; Deferoxamine; Ferritins; Humans | 1991 |
Successful treatment of hemodialysis-related porphyria cutanea tarda with deferoxamine.
Topics: Deferoxamine; Female; Humans; Middle Aged; Porphyrias; Renal Dialysis; Skin Diseases | 1990 |
Desferrioxamine in the treatment of porphyria cutanea tarda: ineffectiveness of intramuscular administration.
Topics: Adult; Deferoxamine; Humans; Injections, Intramuscular; Male; Middle Aged; Porphyrias; Skin Diseases | 1990 |
Increased oxidation of uroporphyrinogen by an inducible liver microsomal system. Possible relevance to drug-induced uroporphyria.
Topics: Aminolevulinic Acid; Animals; Benzoflavones; Cells, Cultured; Chick Embryo; Cytochrome P-450 CYP1A1; | 1988 |
[Evaluation of deferoxamine capacity to revert a severe porphyria induced by hexachlorobenzene].
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Deferoxamine; Hexachlorobenzene; Liver; Porph | 1987 |
Effect of an iron chelator on the onset of hexachlorobenzene-induced porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxy-Lyases; Chlorobenzenes; Deferoxamine; Enzyme Inductio | 1986 |
High weekly intravenous doses of desferrioxamine in porphyria cutanea tarda.
Topics: Aged; Deferoxamine; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Male; Middle A | 1987 |
Iron removal therapy in porphyria cutanea tarda: phlebotomy versus slow subcutaneous desferrioxamine infusion.
Topics: Adult; Bloodletting; Deferoxamine; Female; Humans; Infusions, Parenteral; Iron; Male; Middle Aged; P | 1986 |
Effect of desferrioxamine on the development of hexachlorobenzene-induced porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Body Weight; Carboxy-Lyases; Chlorobenzenes; Deferoxamine; Di | 1986 |
Treatment of hemodialysis-related porphyria cutanea tarda with deferoxamine.
Topics: Adult; Deferoxamine; Humans; Male; Porphyrias; Renal Dialysis; Skin Diseases | 1987 |
Serum ferritin in the assessment of liver iron overload and iron removal therapy in porphyria cutanea tarda.
Topics: Adult; Deferoxamine; Female; Ferritins; Humans; Iron; Liver; Male; Middle Aged; Porphyrias; Skin Dis | 1986 |
Measurement of the labile Iron stores with Singh's technique and chemical determination of Iron contents in organs of rats.
Topics: Animals; Brain Chemistry; Deferoxamine; Erythrocytes; Humans; Iron; Iron Radioisotopes; Kidney; Live | 1973 |
Effect of phenylhydrazine-induced haemolysis on the urinary excretion of iron after desferrioxamine.
Topics: Anemia, Sideroblastic; Animals; Biopsy; Bone Marrow Examination; Deferoxamine; Feces; Guinea Pigs; H | 1967 |
[Treatment of cutaneous porphyrias].
Topics: Adrenocorticotropic Hormone; Anabolic Agents; Deferoxamine; Edetic Acid; Humans; Porphyrias; Skin Di | 1968 |
Biochemical effects of chelation therapy using deferoxamine mesylate on experimental porphyria in rats.
Topics: Animals; Deferoxamine; Male; Porphyrias; Rats | 1972 |
[A case of porphyria cutanea tarda in a 5-year-old child].
Topics: Alkaline Phosphatase; Child, Preschool; Deferoxamine; Humans; Male; Porphyrias; Porphyrins; Transami | 1972 |
[Treatment of late cutaneous porphyrias with iron chelating agents (EDTA, Desferral)].
Topics: Adult; Deferoxamine; Edetic Acid; Humans; Male; Middle Aged; Porphyrias; Skin Diseases | 1967 |
[Clinical and biological effects of chelating agents in porphyria cutanea tarda].
Topics: Adult; Aged; Deferoxamine; Edetic Acid; Feces; Humans; Male; Middle Aged; Porphyrias; Porphyrins | 1968 |
[Treatment of porphyria cutanea tarda by iron chelators (EDTA, Desferral)].
Topics: Adult; Deferoxamine; Edetic Acid; Humans; Male; Middle Aged; Porphyrias | 1967 |
[Therapy of porphyrias].
Topics: Acute Disease; Adenine Nucleotides; Antimalarials; Bicarbonates; Bloodletting; Deferoxamine; Diet Th | 1971 |
Diagnosis of iron storage disease with desferrioxamine (Desferal test).
Topics: Anemia, Macrocytic; Anemia, Sickle Cell; Deferoxamine; Female; Hemochromatosis; Hemosiderosis; Human | 1964 |
[Therapy of porphyrias].
Topics: Acute Disease; Bone Marrow Diseases; Chlorpromazine; Deferoxamine; Erythropoiesis; Humans; Phospholi | 1972 |
Deferoxamine in the treatment of porphyria.
Topics: Deferoxamine; Evaluation Studies as Topic; Female; Hemoglobinometry; Humans; Iron; Levulinic Acids; | 1972 |
Studies on low dose chloroquine therapy and the action of chloroquine in symptomatic porphyria.
Topics: Adult; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chloroquine; Deferoxamine; Humans | 1972 |
[Experiences with iron elimination therapy in porphyria cutanea tarda].
Topics: Adult; Bloodletting; Deferoxamine; Female; Humans; Iron; Liver Diseases; Male; Middle Aged; Porphyri | 1971 |
[Treatment of late cutaneous porphyria by desferal].
Topics: Deferoxamine; Female; Humans; Middle Aged; Porphyrias; Skin Diseases | 1969 |
[Quantitative determination of urinary porphyrins using Rimington's and Sveinsson's technic and experience in the therapy of porphyria cutanea tarda using Desferal CIBA].
Topics: Deferoxamine; Fluorometry; Humans; Methods; Porphyrias; Porphyrins; Spectrophotometry | 1969 |
[Therapy of primary siderochromatosis and siderosis: experimental and clinical study].
Topics: Bloodletting; Deferoxamine; Hemochromatosis; Humans; Intestinal Absorption; Iron; Porphyrias; Primar | 1969 |
Phlebotomy therapy in cutaneous porphyria. Effect on iron and trace metals.
Topics: Aged; Bloodletting; Copper; Deferoxamine; Hematopoiesis; Humans; Iron; Liver Function Tests; Magnesi | 1970 |
[Catamnestic studies in porphyria cutanea tarda with special reference to therapy].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adult; Aged; Bloodletting; Deferoxamine; Diabetes Compl | 1971 |
[Treatment of porphyria cutanea tarda with desferrioxamine (Desferal)].
Topics: Deferoxamine; Humans; Male; Porphyrias | 1967 |
[Favorable clinical and biological action of iron chelator in 4 cases of porphyria cutanea tarda. Attempts at interpretation].
Topics: Adult; Aged; Alcoholism; Deferoxamine; Humans; Male; Porphyrias; Siderosis; Skin Diseases | 1968 |
[Demonstration of increased iron storage in the organism with desferrioxamine (desferal test)].
Topics: Deferoxamine; Hemochromatosis; Hemosiderosis; Humans; Iron; Jaundice; Liver Diseases; Porphyrias | 1965 |
[Porphyria cutanea tarda: study of the changes in porphyrin metabolism during desferrioxamine therapy].
Topics: Deferoxamine; Humans; Porphyrias; Porphyrins | 1965 |