Page last updated: 2024-10-25

deferoxamine and Poisoning

deferoxamine has been researched along with Poisoning in 81 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"To review the adverse effects and risks of deferoxamine for the treatment of iron poisoning."8.79Risks of parenteral deferoxamine for acute iron poisoning. ( Howland, MA, 1996)
"To review the benefits of deferoxamine for the treatment of iron poisoning."8.79Benefits of parenteral deferoxamine for acute iron poisoning. ( Tenenbein, M, 1996)
" He was treated with a unique deferoxamine dosage schedule (25 mg/kg/h for 12 h/d x 3 d), mechanical ventilation, Swan-Ganz catheter monitoring, dopamine/nitroprusside therapy, blood product, bicarbonate, electrolyte and volume replacement."5.29Survival after a severe iron poisoning treated with intermittent infusions of deferoxamine. ( Benson, B; Cheney, K; Gumbiner, C; Tenenbein, M, 1995)
"To review the adverse effects and risks of deferoxamine for the treatment of iron poisoning."4.79Risks of parenteral deferoxamine for acute iron poisoning. ( Howland, MA, 1996)
" The complete treatment of transfusional iron overload in thalassaemia using the deferiprone (L1) and deferoxamine combination is a paradigm to be followed in the treatment of many other metal toxicity conditions."3.79The proceedings of the 20th International Conference on Chelation held in the USA: advances on new and old chelation therapies. ( Kontoghiorghes, GJ, 2013)
"A controversial therapy in the management of acute iron poisoning is the oral administration of deferoxamine which purportedly complexes unabsorbed iron, exerts protection at the cellular level, and/or enhances the renal elimination of ingested iron."3.69Iron complexation with oral deferoxamine in a swine model. ( Dean, BS; Griffith, GR; Hines, RH; Krenzelok, EP; Oehme, FW, 1996)
"To determine whether leukocytosis, hyperglycemia, vomiting, and opacities in abdominal radiographs are indicators of a serum iron concentration of > 300 micrograms/dL in adult iron overdose patients, a retrospective medical record review was undertaken at a university medical center of all patients older than 12 years of age for whom clinical data were collected before deferoxamine therapy and within 6 hours of iron ingestion."3.69Leukocytosis, hyperglycemia, vomiting, and positive X-rays are not indicators of severity of iron overdose in adults. ( Palatnick, W; Tenenbein, M, 1996)
"Traditionally, a serum iron concentration in excess of the total iron-binding capacity (TIBC) is considered as an indication for deferoxamine therapy in acute iron poisoning."3.68The total iron-binding capacity in iron poisoning. Is it useful? ( Tenenbein, M; Yatscoff, RW, 1991)
"Poisonings are a common problem."2.40Clinical applications of commonly used contemporary antidotes. A US perspective. ( Bowden, CA; Krenzelok, EP, 1997)
" Orally effective, safe Al chelators would be of benefit to peritoneal dialysis patients and those with neurodegenerative disorders, if Al chelation therapy is indicated."2.39Prevention and treatment of aluminum toxicity including chelation therapy: status and research needs. ( Ackrill, P; Burgess, E; Day, JP; Domingo, JL; Flaten, TP; Savory, J; Yokel, RA, 1996)
" Fifty-three patients ingested a median toxic dose of elemental iron of 40."1.51Minimum ingested iron cut-off triggering serious iron toxicity in children. ( Halil, H; Karacan, CD; Polat, E; Tuygun, N, 2019)
"Acute iron poisoning is a common and potentially serious problem in the pediatric population."1.39Successful treatment of severe iron intoxication with gastrointestinal decontamination, deferoxamine, and hemodialysis. ( Balwani, MR; Ghuge, PP; Gumber, MR; Kute, VB; Patel, HV; Shah, PR; Trivedi, HL; Vanikar, AV, 2013)
"We report our successful experience treating acute iron poisoning in a 1-year-old girl using whole bowel irrigation and deferoxamine."1.31[Whole bowel irrigation in infants for acute iron poisoning]. ( Rachmel, A; Sokolover, N, 2000)
" He was treated with a unique deferoxamine dosage schedule (25 mg/kg/h for 12 h/d x 3 d), mechanical ventilation, Swan-Ganz catheter monitoring, dopamine/nitroprusside therapy, blood product, bicarbonate, electrolyte and volume replacement."1.29Survival after a severe iron poisoning treated with intermittent infusions of deferoxamine. ( Benson, B; Cheney, K; Gumbiner, C; Tenenbein, M, 1995)
"The drug of choice for the treatment of iron poisoning is desferrioxamine, though the best route of administration, dose, and duration of treatment are unclear."1.28Pulmonary toxic effects of continuous desferrioxamine administration in acute iron poisoning. ( Adamson, IY; Bowden, DH; Kowalski, S; Sienko, A; Tenenbein, M, 1992)
" The optimum route, dosage and frequency of administration of deferoxamine in CAPD patients are not established."1.28Aluminum and deferoxamine kinetics in CAPD. ( Mactier, RA, 1991)

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199037 (45.68)18.7374
1990's31 (38.27)18.2507
2000's7 (8.64)29.6817
2010's6 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Halil, H1
Tuygun, N1
Polat, E1
Karacan, CD1
Gumber, MR1
Kute, VB1
Shah, PR1
Vanikar, AV1
Patel, HV1
Balwani, MR1
Ghuge, PP1
Trivedi, HL1
Fernández, S1
Castro, P1
Nogué, S1
Nicolás, JM1
Aaseth, J2
Skaug, MA1
Cao, Y1
Andersen, O1
Valentine, K1
Mastropietro, C1
Sarnaik, AP1
Chang, TP1
Rangan, C1
Kontoghiorghes, GJ1
Sipahi, T1
Karakurt, C1
Bakirtas, A1
Tavil, B1
WHITTEN, CF1
MOESCHLIN, S2
KAHN, LB1
SHAPIRO, N1
BARBEZAT, GO1
PITTMAN, AK2
SCHNIDER, U1
DUGDALE, AE1
POWELL, LW1
MCENERY, JT1
MACK, RB1
ALBAHARY, C1
BARR, DG1
FRASER, DK1
BURLEY, DM1
FIELDING, J2
CHAVANNE, H1
DEMILLIERE, B1
Yong, RL1
Holmes, DT1
Sreenivasan, GM1
Madiwale, T1
Liebelt, E1
Hyman, S1
Greengard, J2
Goulding, R1
Cheney, K1
Gumbiner, C1
Benson, B1
Tenenbein, M6
Bosse, GM1
Anderson, AC1
Vogelsang, U1
Mills, KC1
Curry, SC1
Davie, MW1
Worsfold, M1
Sharp, CA1
Perks, J1
Day, JP2
Sulková, S2
Olivero, JJ1
Ritz, E1
Barata, JD1
D'Haese, PC1
Pires, C1
Lamberts, LV1
Simões, J1
De Broe, ME1
Dean, BS1
Oehme, FW1
Krenzelok, EP2
Griffith, GR1
Hines, RH1
Palatnick, W1
Yokel, RA1
Ackrill, P1
Burgess, E1
Domingo, JL1
Flaten, TP1
Savory, J1
Howland, MA1
Bowden, CA1
Wang, G1
Zhu, P1
Wang, S1
Gomez, HF1
McClafferty, HH1
Flory, D1
Brent, J1
Dart, RC1
Banner, W1
Cohen, CS1
Roberts, WL1
Smith, PT1
Martin, WJ1
Rainey, PM1
Fine, JS1
Sokolover, N1
Rachmel, A1
Bergeron, RJ1
Wiegand, J1
Brittenham, GM1
Roberts, RJ1
Nayfield, S1
Soper, R1
Kent, TH1
Jones, MM1
Pratt, TH1
Bianchine, JR1
Couri, D1
Kowalski, S1
Sienko, A1
Bowden, DH1
Adamson, IY1
Lacoste, H1
Goyert, GL1
Goldman, LS1
Wright, DJ1
Schwartz, DB1
Durbin, DR1
Wood, BP1
Everson, GW1
Bertaccini, EJ1
O'Leary, J1
Mactier, RA1
Válek, A1
Laurinová, Z1
Bentur, Y1
St Louis, P1
Klein, J1
Koren, G1
Lowrey, S1
Yatscoff, RW2
Wayne, EA1
Canavese, C1
Pacitti, A1
Segoloni, G1
Thea, A1
D'Amicone, M1
Stratta, P1
Rossi, P1
Sabbioni, E1
Pietra, R1
Constantini, S1
Verbeelen, D1
Smeyers-Verbeke, J1
van Hooff, I1
de Roy, G1
Vale, JA1
Meredith, TJ1
Fischer, DS1
Parkman, R1
Finch, SC1
Eriksson, F1
Johansson, SV1
Mellstedt, H1
Stranberg, O1
Wester, PO1
Barker, GA1
Brown, TC1
Hosking, CS1
Filpi, RG1
Majd, M1
LoPresti, JM1
Wirth, W1
Chisolm, JJ1
Robertson, WO1
Green, VA1
Lavender, S1
Bell, JA1
James, JA1
Jonker-Wuite, PG1
Movassaghi, N1
Purugganan, GG1
Leikin, S1
Jacobs, J1
Greene, H1
Gendel, BR1

Reviews

15 reviews available for deferoxamine and Poisoning

ArticleYear
Chelation in metal intoxication--Principles and paradigms.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2015, Volume: 31

    Topics: Administration, Oral; Antidotes; Benzoates; Chelating Agents; Deferasirox; Deferiprone; Deferoxamine

2015
Iron poisoning: a literature-based review of epidemiology, diagnosis, and management.
    Pediatric emergency care, 2011, Volume: 27, Issue:10

    Topics: Animals; Chemistry, Pharmaceutical; Child; Deferoxamine; Drug Packaging; Female; Humans; Iron; Magne

2011
Iron: not a benign therapeutic drug.
    Current opinion in pediatrics, 2006, Volume: 18, Issue:2

    Topics: Chelation Therapy; Child; Deferoxamine; Female; Humans; Iron; Liver; Poisoning; Pregnancy; Pregnancy

2006
Iron poisoning in children.
    Current opinion in pediatrics, 1994, Volume: 6, Issue:3

    Topics: Adolescent; Aftercare; Child; Child, Preschool; Clinical Protocols; Deferoxamine; Emergencies; Gastr

1994
[Aluminum poisoning in dialysis patients--diagnosis and therapy].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1994, Jun-14, Volume: 83, Issue:24

    Topics: Adult; Aged; Aluminum; Deferoxamine; Female; Hemofiltration; Hemoperfusion; Humans; Male; Middle Age

1994
Acute iron poisoning.
    Emergency medicine clinics of North America, 1994, Volume: 12, Issue:2

    Topics: Acute Disease; Chelation Therapy; Deferoxamine; Humans; Iron; Poisoning

1994
Prevention and treatment of aluminum toxicity including chelation therapy: status and research needs.
    Journal of toxicology and environmental health, 1996, Aug-30, Volume: 48, Issue:6

    Topics: Aluminum; Animals; Antidotes; Chelation Therapy; Deferoxamine; Humans; Poisoning; Research Design

1996
Risks of parenteral deferoxamine for acute iron poisoning.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:5

    Topics: Administration, Oral; Antidotes; Communicable Diseases; Deferoxamine; Ear Diseases; Eye Diseases; Hu

1996
Benefits of parenteral deferoxamine for acute iron poisoning.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:5

    Topics: Administration, Oral; Animals; Antidotes; Controlled Clinical Trials as Topic; Deferoxamine; Humans;

1996
Clinical applications of commonly used contemporary antidotes. A US perspective.
    Drug safety, 1997, Volume: 16, Issue:1

    Topics: Acetylcysteine; Antidotes; Antivenins; Atropine; Deferoxamine; Flumazenil; Humans; Hydroxocobalamin;

1997
Iron poisoning.
    Current problems in pediatrics, 2000, Volume: 30, Issue:3

    Topics: Administration, Oral; Chelating Agents; Chelation Therapy; Child; Deferoxamine; Humans; Injections;

2000
Therapeutic chelating agents.
    Journal of chemical education, 1976, Volume: 53, Issue:6

    Topics: Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Humans; Metallothionein; Metals; Penicilla

1976
Acute iron intoxication in pregnancy: case report and review of the literature.
    Obstetrics and gynecology, 1992, Volume: 80, Issue:3 Pt 2

    Topics: Adolescent; Deferoxamine; Delayed-Action Preparations; Female; Ferrous Compounds; Humans; Poisoning;

1992
Antidotal therapy: pharmacokinetic aspects.
    Developments in toxicology and environmental science, 1986, Volume: 12

    Topics: Administration, Oral; Antidotes; Deferoxamine; Dimercaprol; Hot Temperature; Humans; Injections, Int

1986
Treatment of acute iron poisoning.
    Modern treatment, 1971, Volume: 8, Issue:3

    Topics: Acidosis; Acute Disease; Bicarbonates; Deferoxamine; Diarrhea; Edetic Acid; Emetics; Humans; Infusio

1971

Trials

3 trials available for deferoxamine and Poisoning

ArticleYear
[Aluminum poisoning in dialysis patients--diagnosis and therapy].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1994, Jun-14, Volume: 83, Issue:24

    Topics: Adult; Aged; Aluminum; Deferoxamine; Female; Hemofiltration; Hemoperfusion; Humans; Male; Middle Age

1994
Low-dose (5 mg/kg) desferrioxamine treatment in acutely aluminium-intoxicated haemodialysis patients using two drug administration schedules.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aluminum; Antidotes; Deferoxamine; Dose-Response Relationship, Drug;

1996
Prevention of gastrointestinal iron absorption by chelation from an orally administered premixed deferoxamine/charcoal slurry.
    Annals of emergency medicine, 1997, Volume: 30, Issue:5

    Topics: Administration, Oral; Adult; Antidotes; Area Under Curve; Charcoal; Cross-Over Studies; Deferoxamine

1997

Other Studies

64 other studies available for deferoxamine and Poisoning

ArticleYear
Minimum ingested iron cut-off triggering serious iron toxicity in children.
    Pediatrics international : official journal of the Japan Pediatric Society, 2019, Volume: 61, Issue:5

    Topics: Adolescent; Child; Deferoxamine; Eating; Female; Humans; Iron; Male; Poisoning; Retrospective Studie

2019
Successful treatment of severe iron intoxication with gastrointestinal decontamination, deferoxamine, and hemodialysis.
    Renal failure, 2013, Volume: 35, Issue:5

    Topics: Adolescent; Deferoxamine; Female; Gastric Lavage; Heavy Metal Poisoning; Humans; Iron; Poisoning; Re

2013
Acute iron intoxication: change in urine color during chelation therapy with deferoxamine.
    Intensive care medicine, 2014, Volume: 40, Issue:1

    Topics: Chelation Therapy; Color; Deferoxamine; Female; Ferrous Compounds; Heavy Metal Poisoning; Humans; Ir

2014
Infantile iron poisoning: challenges in diagnosis and management.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2009, Volume: 10, Issue:3

    Topics: Deferoxamine; Diagnosis, Differential; Female; Ferrous Compounds; Humans; Infant, Newborn; Poisoning

2009
The proceedings of the 20th International Conference on Chelation held in the USA: advances on new and old chelation therapies.
    Toxicology mechanisms and methods, 2013, Volume: 23, Issue:1

    Topics: Chelating Agents; Chelation Therapy; Deferiprone; Deferoxamine; Edetic Acid; Humans; Iron Overload;

2013
Acute iron ingestion.
    Indian journal of pediatrics, 2002, Volume: 69, Issue:11

    Topics: Child, Preschool; Deferoxamine; Female; Gastric Lavage; Humans; Infant; Iron; Iron Chelating Agents;

2002
ACCIDENTAL IRON POISONING IN CHILDREN.
    Journal of the National Medical Association, 1963, Volume: 55

    Topics: Accident Prevention; Acidosis; Bicarbonates; Chelating Agents; Child; Deferoxamine; Dogs; Humans; Hy

1963
[FREQUENCY, DIAGNOSIS AND TREATMENT OF POISONING IN GENERAL PRACTICE].
    Svenska lakartidningen, 1964, Jun-03, Volume: 61

    Topics: Accidents; Accidents, Occupational; Alcoholic Intoxication; Antidepressive Agents; Carbon Monoxide P

1964
DETERMINATION OF DESFERRIOXAMINE-BOUND IRON IN URINE.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1964, Jul-04, Volume: 38

    Topics: Chelating Agents; Clinical Laboratory Techniques; Deferoxamine; Hydroxamic Acids; Iron; Laboratories

1964
A CASE OF ACUTE IRON POISONING TREATED WITH DESFERRIOXAMINE B.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1964, Jul-04, Volume: 38

    Topics: Chelating Agents; Child; Deferoxamine; Drug Therapy; Heavy Metal Poisoning; Humans; Hydroxamic Acids

1964
DESFERRIOXAMINE AND ACUTE IRON POISONING.
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 1587

    Topics: Deferoxamine; Heavy Metal Poisoning; Injections, Intramuscular; Iron; Iron Metabolism Disorders; Met

1964
DESFERRIOXAMINE AND ACUTE IRON POISONING.
    British medical journal, 1964, Oct-31, Volume: 2, Issue:5417

    Topics: Deferoxamine; Heavy Metal Poisoning; Iron; Iron Metabolism Disorders; Metals, Heavy; Poisoning; Toxi

1964
TREATMENT OF PRIMARY AND SECONDARY HEMOCHROMATOSIS AND ACUTE IRON POISONING WITH A NEW POTENT IRON ELIMINATING AGENT (DESFERRIOXAMINE B-DFOM).
    Nederlands tijdschrift voor geneeskunde, 1964, Aug-22, Volume: 108

    Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Macrocytic; Deferoxamine; Guinea Pigs; Heavy Me

1964
ACUTE IRON POISONING: ITS EFFECTS AND TREATMENT.
    The Medical journal of Australia, 1964, Oct-19, Volume: 2

    Topics: Chelating Agents; Deferoxamine; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Edeti

1964
USE OF DESFERRIOXAMINE IN A CASE OF ACUTE FERROUS SULFATE POISONING.
    IMJ. Illinois medical journal, 1964, Volume: 126

    Topics: Child; Deferoxamine; Drug Therapy; Ferrous Compounds; Heavy Metal Poisoning; Metals, Heavy; Poisonin

1964
[DESFERRIOXAMINE (DF) AND DIETHYLENE TRIAMINE PENTA-ACETIC ACID TRISODIUM CALCIUM SALT (CA DTPA NA3) IN SIDEROSIS. 2].
    La Presse medicale, 1965, Jan-09, Volume: 73

    Topics: Anemia; Anemia, Hypochromic; Blood Transfusion; Calcium; Chelating Agents; Deferoxamine; Drug Therap

1965
MANAGEMENT OF ACUTE IRON POISONING.
    British medical journal, 1965, Mar-06, Volume: 1, Issue:5435

    Topics: Chemical and Drug Induced Liver Injury; Deferoxamine; Hepatitis; Hepatitis A; Iron; Iron Metabolism

1965
MANAGEMENT OF ACUTE IRON POISONING.
    British medical journal, 1965, Apr-10, Volume: 1, Issue:5440

    Topics: Deferoxamine; Drug Therapy; Heavy Metal Poisoning; Iron; Iron Metabolism Disorders; Metals, Heavy; P

1965
[TRIAL OF A NEW IRON CHELATOR, DESFERRIOXAMINE B, IN A CASE OF OCULAR SIDEROSIS].
    Bulletin des societes d'ophtalmologie de France, 1964, Volume: 64

    Topics: Chelating Agents; Deferoxamine; Eye Diseases; Heavy Metal Poisoning; Humans; Iron; Iron Metabolism D

1964
Aluminum toxicity due to intravenous injection of boiled methadone.
    The New England journal of medicine, 2006, Mar-16, Volume: 354, Issue:11

    Topics: Adult; Aluminum; Ataxia; Chelation Therapy; Deferoxamine; Dysarthria; Humans; Male; Methadone; Poiso

2006
Self-poisoning and accidental poisoning.
    Postgraduate medicine, 1967, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Chicago; Child; Deferoxamine; Female; Humans; Iron; Lead Poisoning; Male; Poisoni

1967
The treatment of acute poisoning.
    Transactions of the Medical Society of London, 1967, Volume: 83

    Topics: Acute Disease; Antidotes; Atropine; Barbiturates; Carbon Monoxide Poisoning; Chlorpromazine; Deferox

1967
Survival after a severe iron poisoning treated with intermittent infusions of deferoxamine.
    Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:1

    Topics: Deferoxamine; Drug Administration Schedule; Drug Overdose; Gastric Lavage; Heart; Humans; Infant; In

1995
Conservative management of patients with moderately elevated serum iron levels.
    Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Deferoxamine; Female; Humans; Infant; Iron; Male; Poison

1995
Anomalous rise of serum osteocalcin following desferrioxamine treatment in aluminium intoxication.
    Nephron, 1993, Volume: 65, Issue:2

    Topics: Aluminum; Bone Development; Calcification, Physiologic; Chromatography, Gel; Deferoxamine; Female; H

1993
[Aluminum osteopathy--experience with therapy].
    Vnitrni lekarstvi, 1993, Volume: 39, Issue:5

    Topics: Aluminum; Bone Diseases, Metabolic; Deferoxamine; Female; Humans; Male; Middle Aged; Poisoning; Rena

1993
Hemoptysis and altered sensorium in a hemodialysis patient.
    Hospital practice (Office ed.), 1993, Mar-30, Volume: 28, Issue:3A

    Topics: Aluminum; Aluminum Hydroxide; Brain Diseases; Deferoxamine; Hemoptysis; Humans; Kidney Failure, Chro

1993
[Aluminum accumulation and deferoxamine].
    Deutsche medizinische Wochenschrift (1946), 1993, Jul-02, Volume: 118, Issue:26

    Topics: Aluminum; Deferoxamine; Humans; Middle Aged; Poisoning

1993
Iron complexation with oral deferoxamine in a swine model.
    Veterinary and human toxicology, 1996, Volume: 38, Issue:2

    Topics: Administration, Oral; Animals; Antidotes; Deferoxamine; Disease Models, Animal; Dose-Response Relati

1996
Leukocytosis, hyperglycemia, vomiting, and positive X-rays are not indicators of severity of iron overdose in adults.
    The American journal of emergency medicine, 1996, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Blood Glucose; Deferoxamine; Drug Overdose; Female; Humans; Hyperglycemia; Iron;

1996
[The causes, diagnosis and treatment of aluminum toxicity in patients with chronic renal failure undergoing dialysis].
    Zhonghua nei ke za zhi, 1996, Volume: 35, Issue:1

    Topics: Aluminum; Bone and Bones; Deferoxamine; Humans; Poisoning; Renal Dialysis; Renal Insufficiency; Side

1996
Of iron and ancient mariners.
    Annals of emergency medicine, 1997, Volume: 30, Issue:5

    Topics: Animals; Antidotes; Charcoal; Deferoxamine; Dogs; Ferrous Compounds; Humans; Iron; Poisoning

1997
Studies in acute iron poisoning. I. Desferrioxamine In the treatment of acute iron poisoning: clinical observations, experimental studies, and theoretical considerations, by Charles F. Whitten et al, Pediatrics, 1965;36:322-335; and Studies in acute iron
    Pediatrics, 1998, Volume: 102, Issue:1 Pt 2

    Topics: Acute Disease; Antidotes; Deferoxamine; History, 20th Century; Humans; Iron; Poisoning

1998
Performance characteristics of three serum iron and total iron-binding capacity methods in acute iron overdose.
    American journal of clinical pathology, 1999, Volume: 112, Issue:5

    Topics: Acute Disease; Chelating Agents; Deferoxamine; Drug Overdose; Evaluation Studies as Topic; Humans; I

1999
[Whole bowel irrigation in infants for acute iron poisoning].
    Harefuah, 2000, May-15, Volume: 138, Issue:10

    Topics: Chelating Agents; Child, Preschool; Deferoxamine; Female; Humans; Intestines; Iron; Poisoning; Thera

2000
HBED ligand: preclinical studies of a potential alternative to deferoxamine for treatment of chronic iron overload and acute iron poisoning.
    Blood, 2002, Apr-15, Volume: 99, Issue:8

    Topics: Acute Disease; Animals; Blood Pressure; Cebus; Chronic Disease; Deferoxamine; Disease Models, Animal

2002
Acute iron intoxication with intestinal infarction managed in part by small bowel resection.
    Clinical toxicology, 1975, Volume: 8, Issue:1

    Topics: Deferoxamine; Humans; Ileostomy; Infant; Infarction; Intestinal Diseases; Intestine, Small; Iron; Ma

1975
Management of the drug overdose patient. Part II. Specific antidotes.
    The Ohio State medical journal, 1977, Volume: 73, Issue:7

    Topics: Antidotes; Cholinesterase Inhibitors; Deferoxamine; Humans; Iron; Methanol; Naloxone; Poisoning; Pra

1977
Iron poisoning in children.
    Clinical toxicology, 1975, Volume: 8, Issue:6

    Topics: Chelating Agents; Child; Child, Preschool; Deferoxamine; Exchange Transfusion, Whole Blood; Humans;

1975
Pulmonary toxic effects of continuous desferrioxamine administration in acute iron poisoning.
    Lancet (London, England), 1992, Mar-21, Volume: 339, Issue:8795

    Topics: Acute Disease; Adult; Deferoxamine; Female; Humans; Infusions, Intravenous; Iron; Lung; Male; Poison

1992
Radiological case of the month. Acute iron poisoning and gastrointestinal decontamination procedure.
    American journal of diseases of children (1960), 1992, Volume: 146, Issue:6

    Topics: Deferoxamine; Diagnosis, Differential; Ferrous Compounds; Fluid Therapy; Gastric Lavage; Humans; Inf

1992
Use of whole bowel irrigation in an infant following iron overdose.
    The American journal of emergency medicine, 1991, Volume: 9, Issue:4

    Topics: Deferoxamine; Ferrous Compounds; Humans; Infant; Intestine, Large; Ipecac; Male; Poisoning; Therapeu

1991
Aluminum and deferoxamine kinetics in CAPD.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1991, Volume: 7

    Topics: Aluminum; Deferoxamine; Humans; Peritoneal Dialysis, Continuous Ambulatory; Poisoning

1991
[The causes of aluminum cumulation and poisoning in patients with chronic kidney failure treated by hemodialysis on a regular program and the possibilities for therapy].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:6

    Topics: Aluminum; Aluminum Hydroxide; Calcium Carbonate; Deferoxamine; Hemodialysis Solutions; Hemofiltratio

1991
Misinterpretation of iron-binding capacity in the presence of deferoxamine.
    The Journal of pediatrics, 1991, Volume: 118, Issue:1

    Topics: Animals; Binding Sites; Deferoxamine; Diagnostic Errors; Dogs; Humans; In Vitro Techniques; Iron; Po

1991
Case management of the anemic patient epoetin alfa: focus on aluminum management.
    ANNA journal, 1991, Volume: 18, Issue:1

    Topics: Adult; Aged; Aluminum; Anemia; Deferoxamine; Erythropoietin; Female; Humans; Kidney Failure, Chronic

1991
An objective criterion for the cessation of deferoxamine therapy in the acutely iron poisoned patient.
    Journal of toxicology. Clinical toxicology, 1991, Volume: 29, Issue:1

    Topics: Adult; Creatinine; Deferoxamine; Female; Humans; Iron; Least-Squares Analysis; Male; Poisoning; Refe

1991
The total iron-binding capacity in iron poisoning. Is it useful?
    American journal of diseases of children (1960), 1991, Volume: 145, Issue:4

    Topics: Binding Sites; Clinical Protocols; Deferoxamine; Evaluation Studies as Topic; Humans; Iron; Poisonin

1991
Clinical and histological results of long-term management of aluminium overloading in uraemic patients with desferrioxamine.
    Journal of trace elements and electrolytes in health and disease, 1989, Volume: 3, Issue:1

    Topics: Adult; Aluminum; Bone and Bones; Chelation Therapy; Deferoxamine; Electroencephalography; Female; Fo

1989
The effect of desferrioxamine on tissue aluminum concentration and bone histology in aluminum-loaded rats with renal failure.
    Journal of trace elements and electrolytes in health and disease, 1988, Volume: 2, Issue:2

    Topics: Aluminum; Animals; Bone Diseases; Deferoxamine; Disease Models, Animal; Kidney Failure, Chronic; Mal

1988
Acute iron poisoning in children. The problem of appropriate therapy.
    JAMA, 1971, Nov-22, Volume: 218, Issue:8

    Topics: Adolescent; Adult; Child; Deferoxamine; Enema; Female; Gastric Lavage; Humans; Ipecac; Iron; Male; M

1971
Iron intoxication in two adult patients.
    Acta medica Scandinavica, 1974, Volume: 196, Issue:3

    Topics: Adult; Deferoxamine; Female; Hemoglobins; Hemolysis; Humans; Hypotension; Iron; Jaundice; Liver Func

1974
Acute iron poisoning-clinical features and management.
    Anaesthesia and intensive care, 1974, Volume: 2, Issue:4

    Topics: Acute Disease; Australia; Child, Preschool; Deferoxamine; Female; Gastric Lavage; Humans; Infant; In

1974
Reversible gastric stricture following iron ingestion.
    Southern medical journal, 1973, Volume: 66, Issue:7

    Topics: Blood Transfusion; Cathartics; Constriction; Deferoxamine; Gastric Lavage; Gastrointestinal Hemorrha

1973
[Recent advance in the therapy of metal poisoning with complexing agents].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, May-10, Volume: 12, Issue:13

    Topics: Arsenic Poisoning; Carbon Isotopes; Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Humans

1972
[Possible side-effects of antidotal therapy].
    Archiv fur Toxikologie, 1968, Volume: 24, Issue:1

    Topics: Antidotes; Atropine; Chelating Agents; Cyanides; Deferoxamine; Dimercaprol; Edetic Acid; Humans; Hyd

1968
Poisoning due to heavy metals.
    Pediatric clinics of North America, 1970, Volume: 17, Issue:3

    Topics: Arsenic Poisoning; Cadmium Poisoning; Chelating Agents; Child; Child, Preschool; Copper; Deferoxamin

1970
Iron ingestions--the Children's Mercy Hospital.
    Clinical toxicology, 1971, Volume: 4, Issue:2

    Topics: Aluminum Hydroxide; Antidotes; Child; Child, Preschool; Deferoxamine; Humans; Infant; Iron; Poisonin

1971
Iron intoxication in an adult.
    British medical journal, 1970, May-16, Volume: 2, Issue:5706

    Topics: Acidosis; Adult; Anuria; Deferoxamine; Female; Humans; Iron; Peritoneal Dialysis; Poisoning; Shock,

1970
Acute iron poisoning: assessment of severity and prognosis.
    The Journal of pediatrics, 1970, Volume: 77, Issue:1

    Topics: Child; Deferoxamine; Humans; Hyperglycemia; Iron; Leukocytosis; Poisoning; Prognosis

1970
Storage iron and desferrioxamine.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; De

1970
[Deferoxamine].
    Pharmaceutisch weekblad, 1969, Aug-29, Volume: 104, Issue:35

    Topics: Animals; Deferoxamine; Hemochromatosis; Humans; Iron; Poisoning

1969
Comparison of exchange transfusion and deferoxamine in the treatment of acute iron poisoning.
    The Journal of pediatrics, 1969, Volume: 75, Issue:4

    Topics: Animals; Deferoxamine; Diuresis; Dogs; Exchange Transfusion, Whole Blood; Injections, Intravenous; I

1969
Acute iron intoxication.
    The New England journal of medicine, 1965, Nov-18, Volume: 273, Issue:21

    Topics: Accident Prevention; Deferoxamine; Diagnosis; Female; Humans; Infant; Iron; Poisoning

1965