Page last updated: 2024-10-25

deferoxamine and Pneumonia

deferoxamine has been researched along with Pneumonia in 7 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"Chlorine (Cl(2)) gas exposure poses an environmental and occupational hazard that frequently results in acute lung injury."3.77Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice. ( Bowen, L; Doran, SF; Fernandez, S; Jurkuvenaite, A; Matalon, S; Postlethwait, EM; Squadrito, GL; Yadav, AK; Zarogiannis, SG, 2011)
"Treatment with deferoxamine in vivo failed to influence these in vitro measures of neutrophil oxidative metabolism."1.28Effect of deferoxamine pretreatment on acute pneumonic pasteurellosis and neutrophil oxidative metabolism in calves. ( Killingsworth, CR; Slocombe, RF; Watson, GL, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shvedova, AA1
Kisin, ER1
Murray, AR1
Mouithys-Mickalad, A1
Stadler, K1
Mason, RP1
Kadiiska, M1
Zarogiannis, SG1
Jurkuvenaite, A1
Fernandez, S1
Doran, SF1
Yadav, AK1
Squadrito, GL1
Postlethwait, EM1
Bowen, L1
Matalon, S1
Li, L1
Frei, B1
Ghio, AJ1
Kennedy, TP1
Whorton, AR1
Crumbliss, AL1
Hatch, GE1
Hoidal, JR1
Folkesson, HG1
Weström, BR1
Pierzynowski, SG1
Karlsson, BW1
Slocombe, RF1
Watson, GL1
Killingsworth, CR1
Hosking, CS1

Other Studies

7 other studies available for deferoxamine and Pneumonia

ArticleYear
ESR evidence for in vivo formation of free radicals in tissue of mice exposed to single-walled carbon nanotubes.
    Free radical biology & medicine, 2014, Volume: 73

    Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Cytokines; Deferoxamine; Electron Spin Resonanc

2014
Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice.
    American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:2

    Topics: Acute Lung Injury; Animals; Antioxidants; Ascorbic Acid; Chemical Warfare Agents; Chlorine; Chromato

2011
Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:12

    Topics: Animals; Atherosclerosis; Cell Adhesion Molecules; Cytochrome b Group; Deferoxamine; Female; Gene Ex

2006
Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 1

    Topics: Adsorption; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Dust; Iron; Leukotriene B4; Macroph

1992
Lung to blood passage of different-sized molecules during lung inflammation in the rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:3

    Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Deamino Arginine Vasopressin; Deferoxamine; Dextr

1991
Effect of deferoxamine pretreatment on acute pneumonic pasteurellosis and neutrophil oxidative metabolism in calves.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1990, Volume: 54, Issue:2

    Topics: Acute Disease; Animals; Cattle; Cattle Diseases; Deferoxamine; Iron; Kidney; Neutrophils; Oxidation-

1990
Radiology in the management of acute iron poisoning.
    The Medical journal of Australia, 1969, Mar-15, Volume: 1, Issue:11

    Topics: Acute Disease; Deferoxamine; Diagnosis, Differential; Gastric Lavage; Humans; Infant; Iron; Lung; Ma

1969