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deferoxamine and Peptic Ulcer

deferoxamine has been researched along with Peptic Ulcer in 2 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with probucol (500 mg/kg, p."1.31Oxygen radicals mediate the final exacerbation of endothelin-1-induced gastric ulcer in rat. ( Goto, K; Irukayama-Tomobe, Y; Lazaratos, S; Miyauchi, T; Nakahara, A, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lazaratos, S1
Irukayama-Tomobe, Y1
Miyauchi, T1
Goto, K1
Nakahara, A1
Darnis, F1
Mossé, A1
Breauté, C1
Delorme, ML1

Other Studies

2 other studies available for deferoxamine and Peptic Ulcer

ArticleYear
Oxygen radicals mediate the final exacerbation of endothelin-1-induced gastric ulcer in rat.
    European journal of pharmacology, 2001, Feb-09, Volume: 413, Issue:1

    Topics: Adenosine Triphosphate; Aldehydes; Allopurinol; Animals; Catalase; Deferoxamine; Disease Progression

2001
[Present aspects of the treatment of hemochromatosis (apropos of 100 observations)].
    Annales de medecine interne, 1971, Volume: 122, Issue:12

    Topics: Adult; Alcoholic Intoxication; Bloodletting; Chelating Agents; Chondrocalcinosis; Deferoxamine; Diab

1971