deferoxamine has been researched along with Ovarian Neoplasms in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human ovarian cancer cells and normal human ovarian epithelial cell line IOSE-80 were cultured and administrated with deferoxamine (DFO) or ferric ammonium citrate (FAC)." | 1.62 | Significance of glutathione peroxidase 4 and intracellular iron level in ovarian cancer cells-"utilization" of ferroptosis mechanism. ( Chao, H; Li, D; Zhang, M, 2021) |
| "DFO and DTPA were cytotoxic to ovarian cancer cells in a dose- and time-dependent manner." | 1.33 | Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma. ( Brard, L; Granai, CO; Swamy, N, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, D | 1 |
| Zhang, M | 1 |
| Chao, H | 1 |
| Pourgholami, MH | 1 |
| Cai, ZY | 1 |
| Badar, S | 1 |
| Wangoo, K | 1 |
| Poruchynsky, MS | 1 |
| Morris, DL | 1 |
| Yeung, HY | 1 |
| Lai, KP | 1 |
| Chan, HY | 1 |
| Mak, NK | 1 |
| Wagner, GF | 1 |
| Wong, CK | 1 |
| Brard, L | 1 |
| Granai, CO | 1 |
| Swamy, N | 1 |
4 other studies available for deferoxamine and Ovarian Neoplasms
| Article | Year |
|---|---|
Significance of glutathione peroxidase 4 and intracellular iron level in ovarian cancer cells-"utilization" of ferroptosis mechanism.
Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Deferoxamine; Female; Ferric Compounds; Ferroptos | 2021 |
Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole.
Topics: Albendazole; Angiogenesis Inhibitors; Animals; Cell Hypoxia; Cell Line, Tumor; Deferoxamine; Dose-Re | 2010 |
Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Deferoxamine; Female; Ferric Compounds; Ferricyanides; Glycopro | 2005 |
Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma.
Topics: Animals; Apoptosis; Caspases; Cell Growth Processes; Cell Line, Tumor; Deferoxamine; Enzyme Activati | 2006 |