deferoxamine has been researched along with Osteosarcoma in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteosarcoma is a common malignant bone tumor in clinical orthopedics." | 1.62 | Iron Chelator Induces Apoptosis in Osteosarcoma Cells by Disrupting Intracellular Iron Homeostasis and Activating the MAPK Pathway. ( Lv, H; Shang, P; Wang, S; Xue, Y; Zhang, G; Zhou, L; Zhou, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xue, Y | 1 |
| Zhang, G | 1 |
| Zhou, S | 1 |
| Wang, S | 1 |
| Lv, H | 1 |
| Zhou, L | 1 |
| Shang, P | 1 |
| González Suárez, I | 1 |
| Fernández Martín, JL | 1 |
| Naves Díaz, M | 1 |
| Cannata Andía, JB | 1 |
| Naves, ML | 1 |
| Elorriaga, R | 1 |
| Menéndez-Fraga, P | 1 |
| Jorgetti, V | 1 |
| Cannata, JB | 1 |
| Koizumi, M | 1 |
| Endo, K | 1 |
| Kunimatsu, M | 1 |
| Sakahara, H | 1 |
| Nakashima, T | 1 |
| Kawamura, Y | 1 |
| Watanabe, Y | 1 |
| Saga, T | 1 |
| Konishi, J | 1 |
| Yamamuro, T | 1 |
4 other studies available for deferoxamine and Osteosarcoma
| Article | Year |
|---|---|
Iron Chelator Induces Apoptosis in Osteosarcoma Cells by Disrupting Intracellular Iron Homeostasis and Activating the MAPK Pathway.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Deferasirox; Deferoxamine; Humans; Iro | 2021 |
[Effect of desferrioxamine and deferiprone on osteocalcin secretion in osteoblast-type cells].
Topics: Aluminum; Animals; Bone Neoplasms; Calcitriol; Cattle; Chelating Agents; Culture Media; Deferiprone; | 2003 |
Evaluating the effect of desferrioxamine on bone-cell proliferation.
Topics: Bone and Bones; Cell Division; Deferoxamine; Humans; Osteosarcoma; Tumor Cells, Cultured | 1995 |
67Ga-labeled antibodies for immunoscintigraphy and evaluation of tumor targeting of drug-antibody conjugates in mice.
Topics: Animals; Antibodies, Monoclonal; Deferoxamine; Drug Stability; Gallium Radioisotopes; Mice; Neoplasm | 1988 |