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deferoxamine and Osteonecrosis

deferoxamine has been researched along with Osteonecrosis in 3 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Osteonecrosis: Death of a bone or part of a bone, either atraumatic or posttraumatic.

Research Excerpts

ExcerptRelevanceReference
"In this study, we examined whether local deferoxamine (DFO) administration can promote angiogenesis and bone repair in steroid-induced osteonecrosis of the femoral head (ONFH)."7.81The effect of deferoxamine on angiogenesis and bone repair in steroid-induced osteonecrosis of rabbit femoral heads. ( Dang, X; Fan, L; Li, J; Wang, K; Yu, Z, 2015)
"In this study, we examined whether local deferoxamine (DFO) administration can promote angiogenesis and bone repair in steroid-induced osteonecrosis of the femoral head (ONFH)."3.81The effect of deferoxamine on angiogenesis and bone repair in steroid-induced osteonecrosis of rabbit femoral heads. ( Dang, X; Fan, L; Li, J; Wang, K; Yu, Z, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Jing, X1
Du, T1
Yang, X1
Zhang, W1
Wang, G1
Liu, X1
Li, T1
Jiang, Z1
Li, J1
Fan, L1
Yu, Z1
Dang, X1
Wang, K1
Hertzberg, BP1
Holt, JB1
Graff, RD1
Gilbert, SR1
Dahners, LE1

Other Studies

3 other studies available for deferoxamine and Osteonecrosis

ArticleYear
Desferoxamine protects against glucocorticoid-induced osteonecrosis of the femoral head via activating HIF-1α expression.
    Journal of cellular physiology, 2020, Volume: 235, Issue:12

    Topics: Animals; Bone Regeneration; Deferoxamine; Femur Head; Gene Expression Regulation; Glucocorticoids; H

2020
The effect of deferoxamine on angiogenesis and bone repair in steroid-induced osteonecrosis of rabbit femoral heads.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:2

    Topics: Animals; Bone Morphogenetic Protein 2; Bone Regeneration; Deferoxamine; Disease Models, Animal; Femu

2015
An evaluation of carrier agents for desferoxamine, an up-regulator of vascular endothelial growth factor.
    Journal of biomaterials applications, 2013, Volume: 27, Issue:8

    Topics: Animals; Biocompatible Materials; Bone Matrix; Calcium Sulfate; Collagen; Deferoxamine; Drug Carrier

2013