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deferoxamine and Optic Neuritis

deferoxamine has been researched along with Optic Neuritis in 2 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guy, J1
McGorray, S1
Qi, X1
Fitzsimmons, J1
Mancuso, A1
Rao, N1
Blake, DR1
Winyard, P1
Lunec, J1
Williams, A1
Good, PA1
Crewes, SJ1
Gutteridge, JM1
Rowley, D1
Halliwell, B1
Cornish, A1

Other Studies

2 other studies available for deferoxamine and Optic Neuritis

ArticleYear
Conjugated deferoxamine reduces blood-brain barrier disruption in experimental optic neuritis.
    Ophthalmic research, 1994, Volume: 26, Issue:5

    Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Deferoxamine; Disease Models, Animal; Encephal

1994
Cerebral and ocular toxicity induced by desferrioxamine.
    The Quarterly journal of medicine, 1985, Volume: 56, Issue:219

    Topics: Adult; Aged; Animals; Brain; Deferoxamine; Drug Interactions; Drug Therapy, Combination; Female; Fun

1985