deferoxamine has been researched along with Optic Neuritis in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Guy, J | 1 |
McGorray, S | 1 |
Qi, X | 1 |
Fitzsimmons, J | 1 |
Mancuso, A | 1 |
Rao, N | 1 |
Blake, DR | 1 |
Winyard, P | 1 |
Lunec, J | 1 |
Williams, A | 1 |
Good, PA | 1 |
Crewes, SJ | 1 |
Gutteridge, JM | 1 |
Rowley, D | 1 |
Halliwell, B | 1 |
Cornish, A | 1 |
2 other studies available for deferoxamine and Optic Neuritis
Article | Year |
---|---|
Conjugated deferoxamine reduces blood-brain barrier disruption in experimental optic neuritis.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Deferoxamine; Disease Models, Animal; Encephal | 1994 |
Cerebral and ocular toxicity induced by desferrioxamine.
Topics: Adult; Aged; Animals; Brain; Deferoxamine; Drug Interactions; Drug Therapy, Combination; Female; Fun | 1985 |