deferoxamine has been researched along with Neurodegenerative Diseases in 8 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X | 1 |
| Li, D | 1 |
| Sun, HY | 1 |
| Wang, WW | 1 |
| Wu, H | 1 |
| Kong, W | 1 |
| Kong, WJ | 1 |
| Gasparotto, J | 1 |
| Senger, MR | 1 |
| Telles de Sá Moreira, E | 1 |
| Brum, PO | 1 |
| Carazza Kessler, FG | 1 |
| Peixoto, DO | 1 |
| Panzenhagen, AC | 1 |
| Ong, LK | 1 |
| Campos Soares, M | 1 |
| Reis, PA | 1 |
| Schirato, GV | 1 |
| Góes Valente, WC | 1 |
| Araújo Montoya, BO | 1 |
| Silva, FP | 1 |
| Fonseca Moreira, JC | 1 |
| Dal-Pizzol, F | 1 |
| Castro-Faria-Neto, HC | 1 |
| Gelain, DP | 1 |
| Badat, M | 1 |
| Kaya, B | 1 |
| Telfer, P | 1 |
| Pelucchi, S | 1 |
| Pelloni, I | 1 |
| Arosio, C | 1 |
| Mariani, R | 1 |
| Piperno, A | 1 |
| Sripetchwandee, J | 1 |
| Wongjaikam, S | 1 |
| Krintratun, W | 1 |
| Chattipakorn, N | 1 |
| Chattipakorn, SC | 1 |
| Pan, PL | 1 |
| Tang, HH | 1 |
| Chen, Q | 1 |
| Song, W | 1 |
| Shang, HF | 1 |
| Youdim, MB | 1 |
| Stephenson, G | 1 |
| Ben Shachar, D | 1 |
| Kruck, TP | 1 |
| Cui, JG | 1 |
| Percy, ME | 1 |
| Lukiw, WJ | 1 |
8 other studies available for deferoxamine and Neurodegenerative Diseases
| Article | Year |
|---|---|
Relieving ferroptosis may partially reverse neurodegeneration of the auditory cortex.
Topics: Age Factors; Animals; Apoptosis; Auditory Cortex; Chelating Agents; Deferoxamine; Ferroptosis; Gene | 2020 |
Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease.
Topics: Acetylcysteine; Animals; Anthelmintics; Astrocytes; Deferoxamine; Disease Models, Animal; Free Radic | 2021 |
Combination-therapy with concurrent deferoxamine and deferiprone is effective in treating resistant cardiac iron-loading in aceruloplasminaemia.
Topics: Adult; Ceruloplasmin; Deferiprone; Deferoxamine; Drug Therapy, Combination; Heart Diseases; Humans; | 2015 |
Does aceruloplasminemia modulate iron phenotype in thalassemia intermedia?
Topics: alpha-Globins; Base Sequence; beta-Globins; beta-Thalassemia; Ceruloplasmin; Deferoxamine; Exons; Ge | 2016 |
A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload.
Topics: Acetylcysteine; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Benzoates; Brain; Deferasir | 2016 |
Desferrioxamine treatment of aceruloplasminemia: Long-term follow-up.
Topics: Brain; Ceruloplasmin; Deferoxamine; Female; Humans; Iron Metabolism Disorders; Longitudinal Studies; | 2011 |
Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Brain; Brocresine; | 2004 |
Molecular shuttle chelation: the use of ascorbate, desferrioxamine and Feralex-G in combination to remove nuclear bound aluminum.
Topics: Aged; Aluminum; Ascorbic Acid; Binding Sites; Brain Chemistry; Cell Nucleus; Chelating Agents; Chela | 2004 |