deferoxamine has been researched along with Nephrotic Syndrome in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a separate in vivo study, the iron chelator, deferoxamine, prevented the increase in the bleomycin-detectable iron in glomeruli and provided complete protection against proteinuria." | 3.69 | Role of 'catalytic' iron in an animal model of minimal change nephrotic syndrome. ( Baliga, R; Shah, SV; Ueda, N, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lange, B | 1 |
| Hofweber, K | 1 |
| Waldherr, R | 1 |
| Schärer, K | 1 |
| Ueda, N | 1 |
| Baliga, R | 1 |
| Shah, SV | 1 |
| Alfrey, AC | 1 |
| Dagg, JH | 1 |
| Smith, JA | 1 |
| Goldberg, A | 1 |
4 other studies available for deferoxamine and Nephrotic Syndrome
| Article | Year |
|---|---|
Congenital erythropoietic porphyria associated with nephrotic syndrome and renal siderosis.
Topics: Anti-Inflammatory Agents; Child; Deferoxamine; Glomerular Filtration Rate; Humans; Iron Chelating Ag | 1995 |
Role of 'catalytic' iron in an animal model of minimal change nephrotic syndrome.
Topics: Animals; Bleomycin; Deferoxamine; Disease Models, Animal; Iron; Kidney Glomerulus; Kidney Tubules; M | 1996 |
Toxicity of tubule fluid iron in the nephrotic syndrome.
Topics: Animals; Bleomycin; Creatinine; Deferoxamine; Iron; Iron Chelating Agents; Kidney Tubules; Male; Nep | 1992 |
Urinary excretion of iron.
Topics: Adolescent; Adult; Aged; Anemia, Hypochromic; Animals; Child; Deferoxamine; Female; Hemoglobinuria; | 1966 |