deferoxamine has been researched along with Neoplasms, Germ Cell and Embryonal in 1 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Neoplasms, Germ Cell and Embryonal: Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In view of the high relapse rate following chemotherapy for patients with advanced neuroblastoma (NB) and primitive neuroectodermal tumors (PNET), we designed a novel chemotherapy program which incorporated the iron chelator deferoxamine." | 5.07 | D-CECaT: a breakthrough for patients with neuroblastoma. ( Angioni, A; Boglino, C; Cozza, R; Deb, G; Donfrancesco, A; Helson, L; Jenkner, A; Landolfo, A; Maurizio, C, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Donfrancesco, A | 1 |
| Deb, G | 1 |
| Angioni, A | 1 |
| Maurizio, C | 1 |
| Cozza, R | 1 |
| Jenkner, A | 1 |
| Landolfo, A | 1 |
| Boglino, C | 1 |
| Helson, L | 1 |
1 trial available for deferoxamine and Neoplasms, Germ Cell and Embryonal
| Article | Year |
|---|---|
D-CECaT: a breakthrough for patients with neuroblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Carboplatin; Child; Child, Prescho | 1993 |