deferoxamine has been researched along with Necrosis in 42 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "N-acetylcysteine plus deferoxamine treatment significantly attenuated hepatic and central nervous system oxidative damage after acute hepatic failure induced by CCl4." | 7.72 | Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats. ( Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J, 2004) |
| "5 g twice weekly for aluminum bone disease developed fever and bilateral calf pain caused by myonecrosis with gas gangrene." | 7.69 | Fatal Aeromonas hydrophila bacteremia in a hemodialysis patient treated with deferoxamine. ( Boelaert, JR; De Brauwer, E; Gordts, B; Lin, SH; Lin, YF; Shieh, SD; Van Landuyt, HW, 1996) |
| "The hepatic necrosis produced in Fischer-344 rats by diquat appears to be mediated by redox cycling of diquat with generation of reactive oxygen species." | 7.67 | Evidence for participation of lipid peroxidation and iron in diquat-induced hepatic necrosis in vivo. ( Smith, CV, 1987) |
| "Deferoxamine has decreased flap necrosis in the porcine model and may be of use in augmenting the surviving length of flaps in human beings." | 5.28 | Deferoxamine decreases necrosis in dorsally based pig skin flaps. ( Maves, MD; McCormack, ML; Weinstein, GS, 1989) |
| "Although the systemic administration of deferoxamine (DFO) is protective in experimental models of normal ischemic flap and diabetic wound, its effect on diabetic flap ischemia using a local injection remains unknown." | 3.80 | Local injection of deferoxamine improves neovascularization in ischemic diabetic random flap by increasing HIF-1α and VEGF expression. ( Cai, Y; Cui, L; Li, G; Wang, C; Xiong, Z; Zhang, Y, 2014) |
| "N-acetylcysteine plus deferoxamine treatment significantly attenuated hepatic and central nervous system oxidative damage after acute hepatic failure induced by CCl4." | 3.72 | Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats. ( Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J, 2004) |
| "5 g twice weekly for aluminum bone disease developed fever and bilateral calf pain caused by myonecrosis with gas gangrene." | 3.69 | Fatal Aeromonas hydrophila bacteremia in a hemodialysis patient treated with deferoxamine. ( Boelaert, JR; De Brauwer, E; Gordts, B; Lin, SH; Lin, YF; Shieh, SD; Van Landuyt, HW, 1996) |
| " We have demonstrated previously that lipid A, the biologically active component of lipopolysaccharide (LPS), or endotoxin, induces dose-dependent necrosis of isolated rat renal tubular cells (RTCs)." | 3.67 | Enhancement of endotoxin-induced isolated renal tubular cell injury by toxic shock syndrome toxin 1. ( Gekker, G; Keane, WF; Peterson, PK; Schlievert, PM, 1986) |
| "The hepatic necrosis produced in Fischer-344 rats by diquat appears to be mediated by redox cycling of diquat with generation of reactive oxygen species." | 3.67 | Evidence for participation of lipid peroxidation and iron in diquat-induced hepatic necrosis in vivo. ( Smith, CV, 1987) |
| "The deferoxamine dose was five times greater than the maximally tolerated dose of free deferoxamine." | 2.67 | High-dose iron-chelator therapy during reperfusion with deferoxamine-hydroxyethyl starch conjugate fails to reduce canine infarct size. ( Hallaway, PE; Hedlund, BE; Horwitz, LD; Lesnefsky, EJ, 1990) |
| "Iron is potentially toxic to oligodendrocyte progenitors due to its high intracellular levels and its ability to catalyse oxidant-producing reactions." | 1.33 | Iron contributes to dopamine-induced toxicity in oligodendrocyte progenitors. ( Almazan, G; Hemdan, S, 2006) |
| "Treatment with gadolinium chloride (GdCl3) selectively reduced the capacity of Kupffer cells to generate superoxide by 65% and attenuated liver injury by 73% at 4 h and 58-69% at 24 h." | 1.29 | Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia. ( Farhood, A; Fisher, MA; Jaeschke, H; Liu, P; McGuire, GM; Smith, CW, 1995) |
| " Although the exact sequence of its hepatotoxic factors is unproven, it seems likely that lipid peroxidation through the dysfunction of antioxidant defence factors and a toxic metabolite contribute to the formation of this liver injury." | 1.28 | Hepatotoxicity of diethyldithiocarbamate in rats. ( Hobara, T; Ishiyama, H; Kanbe, T; Ogino, K; Shimomura, Y, 1990) |
| "Frostbite is characterized by acute tissue injury induced by freezing and thawing." | 1.28 | Evidence for an early free radical-mediated reperfusion injury in frostbite. ( Bulkley, GB; Im, MJ; Jesudass, R; Manson, PN; Marzella, L; Narayan, KK, 1991) |
| "Flap necrosis was assessed on postoperative day 5." | 1.27 | A free radical scavenger reduces hematoma-induced flap necrosis in Fischer rats. ( Abramson, M; Angel, MF; Haddad, J, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (21.43) | 18.7374 |
| 1990's | 13 (30.95) | 18.2507 |
| 2000's | 12 (28.57) | 29.6817 |
| 2010's | 6 (14.29) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, L | 1 |
| Müller, DC | 1 |
| Kammerecker, S | 1 |
| Fluri, M | 1 |
| Neutsch, L | 1 |
| Remus Emsermann, M | 1 |
| Pelludat, C | 1 |
| Nasir, NJM | 1 |
| Heemskerk, H | 1 |
| Jenkins, J | 1 |
| Hamadee, NH | 1 |
| Bunte, R | 1 |
| Tucker-Kellogg, L | 1 |
| Singla, S | 1 |
| Sysol, JR | 1 |
| Dille, B | 1 |
| Jones, N | 1 |
| Chen, J | 1 |
| Machado, RF | 1 |
| Wang, C | 1 |
| Cai, Y | 1 |
| Zhang, Y | 1 |
| Xiong, Z | 1 |
| Li, G | 1 |
| Cui, L | 1 |
| Duscher, D | 1 |
| Neofytou, E | 1 |
| Wong, VW | 1 |
| Maan, ZN | 1 |
| Rennert, RC | 1 |
| Inayathullah, M | 1 |
| Januszyk, M | 1 |
| Rodrigues, M | 1 |
| Malkovskiy, AV | 1 |
| Whitmore, AJ | 1 |
| Walmsley, GG | 1 |
| Galvez, MG | 1 |
| Whittam, AJ | 1 |
| Brownlee, M | 1 |
| Rajadas, J | 1 |
| Gurtner, GC | 1 |
| Egashira, Y | 1 |
| Xi, G | 1 |
| Chaudhary, N | 1 |
| Hua, Y | 1 |
| Pandey, AS | 1 |
| Kostopanagiotou, GG | 1 |
| Kalimeris, KA | 1 |
| Arkadopoulos, NP | 1 |
| Pafiti, A | 1 |
| Panagopoulos, D | 1 |
| Smyrniotis, V | 1 |
| Vlahakos, D | 1 |
| Routsi, C | 1 |
| Lekka, ME | 1 |
| Nakos, G | 1 |
| Najafzadeh, H | 1 |
| Jalali, MR | 1 |
| Morovvati, H | 1 |
| Taravati, F | 1 |
| Weng, R | 1 |
| Li, Q | 1 |
| Li, H | 1 |
| Yang, M | 1 |
| Sheng, L | 1 |
| Chiou, TJ | 1 |
| Chu, ST | 1 |
| Tzeng, WF | 1 |
| Zhong, JL | 1 |
| Yiakouvaki, A | 1 |
| Holley, P | 1 |
| Tyrrell, RM | 1 |
| Pourzand, C | 1 |
| Ritter, C | 1 |
| Reinke, A | 1 |
| Andrades, M | 1 |
| Martins, MR | 1 |
| Rocha, J | 1 |
| Menna-Barreto, S | 1 |
| Quevedo, J | 1 |
| Moreira, JC | 1 |
| Dal-Pizzol, F | 1 |
| Vairetti, M | 1 |
| Ferrigno, A | 1 |
| Bertone, R | 1 |
| Richelmi, P | 1 |
| Bertè, F | 1 |
| Freitas, I | 1 |
| Gross, J | 1 |
| Fuchs, J | 1 |
| Machulik, A | 1 |
| Jahnke, V | 1 |
| Kietzmann, T | 1 |
| Bockmühl, U | 1 |
| Kurz, T | 1 |
| Gustafsson, B | 1 |
| Brunk, UT | 2 |
| Hemdan, S | 1 |
| Almazan, G | 1 |
| Scuro, LA | 1 |
| Dobrilla, G | 1 |
| Liu, P | 1 |
| McGuire, GM | 1 |
| Fisher, MA | 1 |
| Farhood, A | 1 |
| Smith, CW | 1 |
| Jaeschke, H | 1 |
| Ben Ismail, TH | 1 |
| Ali, BH | 1 |
| Bashir, AA | 1 |
| Lin, SH | 1 |
| Shieh, SD | 1 |
| Lin, YF | 1 |
| De Brauwer, E | 1 |
| Van Landuyt, HW | 1 |
| Gordts, B | 1 |
| Boelaert, JR | 1 |
| Chatterjee, PK | 2 |
| Cuzzocrea, S | 2 |
| Thiemermann, C | 2 |
| Pincemail, J | 1 |
| Defraigne, JO | 1 |
| Detry, O | 1 |
| Franssen, C | 1 |
| Meurisse, M | 1 |
| Limet, R | 1 |
| Brown, PA | 1 |
| Zacharowski, K | 1 |
| Stewart, KN | 1 |
| Mota-Filipe, H | 1 |
| Olejnicka, BT | 1 |
| Andersson, A | 1 |
| Tyrberg, B | 1 |
| Dalen, H | 1 |
| Antunes, F | 1 |
| Cadenas, E | 1 |
| Sugimoto, K | 1 |
| Tamayose, K | 1 |
| Sasaki, M | 1 |
| Hayashi, K | 1 |
| Oshimi, K | 1 |
| Diaz, DD | 1 |
| Freeman, SB | 1 |
| Wilson, JF | 1 |
| Parker, GS | 1 |
| Sakaida, I | 1 |
| Kayano, K | 1 |
| Kubota, M | 1 |
| Mori, K | 1 |
| Takenaka, K | 1 |
| Yasunaga, M | 1 |
| Okita, K | 1 |
| Lesnefsky, EJ | 1 |
| Hedlund, BE | 1 |
| Hallaway, PE | 1 |
| Horwitz, LD | 1 |
| Klibanov, AL | 1 |
| Khaw, BA | 1 |
| Nossiff, N | 1 |
| O'Donnell, SM | 1 |
| Huang, L | 1 |
| Slinkin, MA | 1 |
| Torchilin, VP | 1 |
| Ishiyama, H | 1 |
| Ogino, K | 1 |
| Shimomura, Y | 1 |
| Kanbe, T | 1 |
| Hobara, T | 1 |
| Manson, PN | 1 |
| Jesudass, R | 1 |
| Marzella, L | 1 |
| Bulkley, GB | 1 |
| Im, MJ | 1 |
| Narayan, KK | 1 |
| Iyengar, J | 1 |
| George, A | 1 |
| Russell, JC | 1 |
| Das, DK | 1 |
| Hornsey, S | 1 |
| Myers, R | 1 |
| Jenkinson, T | 1 |
| Weinstein, GS | 1 |
| Maves, MD | 1 |
| McCormack, ML | 1 |
| Green, CJ | 1 |
| Dhami, L | 1 |
| Prasad, S | 1 |
| Healing, G | 1 |
| Shurey, C | 1 |
| Banner, W | 1 |
| Tong, TG | 1 |
| Keane, WF | 1 |
| Gekker, G | 1 |
| Schlievert, PM | 1 |
| Peterson, PK | 1 |
| Angel, MF | 2 |
| Haddad, J | 1 |
| Abramson, M | 1 |
| Casini, AF | 1 |
| Maellaro, E | 1 |
| Pompella, A | 1 |
| Ferrali, M | 1 |
| Comporti, M | 1 |
| Smith, CV | 1 |
| Narayanan, K | 1 |
| Swartz, WM | 1 |
| Ramasastry, SS | 1 |
| Kuhns, DB | 1 |
| Basford, RE | 1 |
| Futrell, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes[NCT03085771] | Phase 2 | 30 participants (Anticipated) | Interventional | 2017-01-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for deferoxamine and Necrosis
| Article | Year |
|---|---|
Iron poisoning.
Topics: Absorption; Bicarbonates; Chemical and Drug Induced Liver Injury; Child, Preschool; Deferoxamine; Di | 1986 |
1 trial available for deferoxamine and Necrosis
| Article | Year |
|---|---|
High-dose iron-chelator therapy during reperfusion with deferoxamine-hydroxyethyl starch conjugate fails to reduce canine infarct size.
Topics: Analysis of Variance; Animals; Deferoxamine; Dogs; Dose-Response Relationship, Drug; Double-Blind Me | 1990 |
40 other studies available for deferoxamine and Necrosis
| Article | Year |
|---|---|
Priority Effects in the Apple Flower Determine If the Siderophore Desferrioxamine Is a Virulence Factor for Erwinia amylovora CFBP1430.
Topics: Deferoxamine; Erwinia amylovora; Flowers; Iron; Malus; Necrosis; Plant Diseases; Siderophores; Virul | 2022 |
Myoglobin-derived iron causes wound enlargement and impaired regeneration in pressure injuries of muscle.
Topics: Animals; Deferoxamine; Humans; Iron; Mice; Muscles; Myoglobin; Necrosis; Pressure Ulcer | 2023 |
Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell Death.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Deferoxamine; Dextrans; Electric Impedance; E | 2017 |
Local injection of deferoxamine improves neovascularization in ischemic diabetic random flap by increasing HIF-1α and VEGF expression.
Topics: Animals; Cell Movement; Cell Survival; Deferoxamine; Diabetes Mellitus, Experimental; Dose-Response | 2014 |
Transdermal deferoxamine prevents pressure-induced diabetic ulcers.
Topics: Administration, Cutaneous; Animals; Apoptosis; Deferoxamine; Dermis; Diabetes Complications; Diabete | 2015 |
Acute Brain Injury after Subarachnoid Hemorrhage.
Topics: Acute Disease; Acute-Phase Proteins; Animals; Brain Injuries; Brain Ischemia; Deferoxamine; Hemoglob | 2015 |
Desferrioxamine attenuates minor lung injury following surgical acute liver failure.
Topics: Acute Lung Injury; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Catalase; Deferoxami | 2009 |
Comparison of the prophylactic effect of silymarin and deferoxamine on iron overload-induced hepatotoxicity in rat.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug | 2010 |
Mimic hypoxia improves angiogenesis in ischaemic random flaps.
Topics: Animals; Cell Survival; Cells, Cultured; Deferoxamine; Endothelial Cells; Fibroblasts; Ischemia; Mal | 2010 |
Protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cysteine; Deferoxamine; Drug Interactions; Flow Cytometry; | 2003 |
Susceptibility of skin cells to UVA-induced necrotic cell death reflects the intracellular level of labile iron.
Topics: Adenosine Triphosphate; Cell Death; Cell Line; Deferoxamine; Dose-Response Relationship, Radiation; | 2004 |
Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Deferoxamine; Hydrocarbons; Inflammatio | 2004 |
Apoptosis vs. necrosis: glutathione-mediated cell death during rewarming of rat hepatocytes.
Topics: Analysis of Variance; Animals; Annexin A5; Apoptosis; Buthionine Sulfoximine; Cell Count; Deferoxami | 2005 |
Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures.
Topics: Acetylcysteine; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; C | 2005 |
Intralysosomal iron chelation protects against oxidative stress-induced cellular damage.
Topics: Aldehydes; Apoptosis; Cell Proliferation; Chelating Agents; Deferoxamine; Endocytosis; Hydrazones; H | 2006 |
Iron contributes to dopamine-induced toxicity in oligodendrocyte progenitors.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Nucleus; Deferoxamine; Dopamine; Do | 2006 |
Siderosis, haemolysis or hepatonecrosis in increasing post-desferrioxamine sideruria in acute viral hepatitis?
Topics: Deferoxamine; Hemolysis; Hepatitis A; Humans; Iron; Liver Diseases; Necrosis; Siderosis | 1967 |
Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia.
Topics: Animals; Antibodies, Monoclonal; CD11 Antigens; Chromans; Deferoxamine; Gadolinium; Ischemia; Kupffe | 1995 |
Influence of iron, deferoxamine and ascorbic acid on gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Ascorbic Acid; Blood Urea Nitrogen; Creatinine; Deferoxamine; Dose-Response Relationship, D | 1994 |
Fatal Aeromonas hydrophila bacteremia in a hemodialysis patient treated with deferoxamine.
Topics: Aeromonas hydrophila; Aluminum; Antidotes; Bacteremia; Bone Diseases; Deferoxamine; Fatal Outcome; F | 1996 |
Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress.
Topics: Animals; Benzamides; Catalase; Cells, Cultured; Deferoxamine; DNA Damage; Enzyme Activation; Enzyme | 1999 |
Ischemia-reperfusion injury of rabbit kidney: comparative effects of desferrioxamine and N-acetylcysteine as antioxidants.
Topics: Acetylcysteine; Animals; Antioxidants; Aspartate Aminotransferases; Deferoxamine; Glutathione; Ische | 2000 |
Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat.
Topics: Acute Kidney Injury; Animals; Cell Membrane Permeability; Cell Separation; Cells, Cultured; Chelatin | 2000 |
Beta-cells, oxidative stress, lysosomal stability, and apoptotic/necrotic cell death.
Topics: Animals; Apoptosis; Autophagy; Cells, Cultured; Deferoxamine; Glucose; Histocytochemistry; Hydrogen | 1999 |
Cellular titration of apoptosis with steady state concentrations of H(2)O(2): submicromolar levels of H(2)O(2) induce apoptosis through Fenton chemistry independent of the cellular thiol state.
Topics: 2,2'-Dipyridyl; Apoptosis; Carmustine; Chelating Agents; Deferoxamine; Diamide; Enzyme Inhibitors; F | 2001 |
Low-dose doxorubicin-induced necrosis in Jurkat cells and its acceleration and conversion to apoptosis by antioxidants.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Cyclic N-Oxides; Deferoxamine; Doxorubicin; Flow Cyt | 2002 |
Hematoma-induced flap necrosis and free radical scavengers.
Topics: Animals; Deferoxamine; Female; Free Radical Scavengers; Hematoma; Necrosis; Surgical Flaps; Swine; T | 1992 |
Protective effect of deferoxamine for acetaminophen induced liver injury.
Topics: Acetaminophen; Animals; Deferoxamine; Dose-Response Relationship, Drug; Liver; Male; Necrosis; Rats; | 1992 |
Targeting of macromolecular carriers and liposomes by antibodies to myosin heavy chain.
Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Deferoxamine; Drug Carriers; Liposomes; Macromole | 1991 |
Hepatotoxicity of diethyldithiocarbamate in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Deferoxamine; Ditiocarb; Gluta | 1990 |
Evidence for an early free radical-mediated reperfusion injury in frostbite.
Topics: Allopurinol; Animals; Deferoxamine; Disease Models, Animal; Ear; Free Radicals; Freezing; Frostbite; | 1991 |
The effects of an iron chelator on cellular injury induced by vascular stasis caused by hypothermia.
Topics: Animals; Creatine Kinase; Deferoxamine; Hindlimb; Hydroxides; Hydroxyl Radical; Hypothermia, Induced | 1990 |
The reduction of radiation damage to the spinal cord by post-irradiation administration of vasoactive drugs.
Topics: Animals; Deferoxamine; Dipyridamole; Male; Necrosis; Radiation Injuries, Experimental; Rats; Reperfu | 1990 |
Deferoxamine decreases necrosis in dorsally based pig skin flaps.
Topics: Animals; Deferoxamine; Female; Graft Survival; Injections, Intramuscular; Necrosis; Surgical Flaps; | 1989 |
The effect of desferrioxamine on lipid peroxidation and survival of ischaemic island skin flaps in rats.
Topics: Animals; Deferoxamine; Female; Graft Survival; Ischemia; Lipid Peroxidation; Necrosis; Rats; Rats, I | 1989 |
Enhancement of endotoxin-induced isolated renal tubular cell injury by toxic shock syndrome toxin 1.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Cell Separation; Cell Survival; Chlo | 1986 |
A free radical scavenger reduces hematoma-induced flap necrosis in Fischer rats.
Topics: Animals; Deferoxamine; Graft Survival; Hematoma; Male; Necrosis; Postoperative Complications; Rats; | 1987 |
Lipid peroxidation, protein thiols and calcium homeostasis in bromobenzene-induced liver damage.
Topics: Alanine Transaminase; Animals; Bromobenzenes; Calcium; Deferoxamine; Glutathione; Homeostasis; Lipid | 1988 |
Evidence for participation of lipid peroxidation and iron in diquat-induced hepatic necrosis in vivo.
Topics: Animals; Chemical Phenomena; Chemistry; Deferoxamine; Diquat; Ethane; Ferrous Compounds; Glutathione | 1987 |
Deferoxamine increases skin flap survival: additional evidence of free radical involvement in ischaemic flap surgery.
Topics: Animals; Deferoxamine; Free Radicals; Graft Survival; Male; Malondialdehyde; Necrosis; Rats; Rats, I | 1986 |