deferoxamine has been researched along with Myoglobinuria in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Myoglobinuria: The presence of MYOGLOBIN in URINE usually as a result of rhabdomyolysis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plotnikov, EY | 1 |
| Chupyrkina, AA | 1 |
| Pevzner, IB | 1 |
| Isaev, NK | 1 |
| Zorov, DB | 1 |
| Groebler, LK | 1 |
| Liu, J | 1 |
| Shanu, A | 1 |
| Codd, R | 1 |
| Witting, PK | 1 |
| Zager, RA | 2 |
| Burkhart, KM | 1 |
| Conrad, DS | 1 |
| Gmur, DJ | 1 |
4 other studies available for deferoxamine and Myoglobinuria
| Article | Year |
|---|---|
Myoglobin causes oxidative stress, increase of NO production and dysfunction of kidney's mitochondria.
Topics: Animals; Antioxidants; Cell Respiration; Deferoxamine; Free Radical Scavengers; Humans; Iron Chelati | 2009 |
Comparing the potential renal protective activity of desferrioxamine B and the novel chelator desferrioxamine B-N-(3-hydroxyadamant-1-yl)carboxamide in a cell model of myoglobinuria.
Topics: Animals; Cell Line; Chelating Agents; Deferoxamine; Dogs; Endocytosis; Epithelial Cells; Gene Expres | 2011 |
Iron, heme oxygenase, and glutathione: effects on myohemoglobinuric proximal tubular injury.
Topics: Animals; Cell-Free System; Deferoxamine; Free Radical Scavengers; Glutathione; Glycerol; Heme Oxygen | 1995 |
Combined mannitol and deferoxamine therapy for myohemoglobinuric renal injury and oxidant tubular stress. Mechanistic and therapeutic implications.
Topics: Acute Kidney Injury; Animals; Deferoxamine; Drug Therapy, Combination; Hydrogen Peroxide; Hydroxides | 1992 |