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deferoxamine and Muscle Contraction

deferoxamine has been researched along with Muscle Contraction in 14 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" Iron chelation and iron overload was achieved by deferoxamine mesylate or iron dextran injection."8.02Iron chelation suppresses secondary bleeding after intracerebral hemorrhage in angiotensin II-infused mice. ( Chen, WX; Feng, H; Ge, HF; Guo, C; Li, CC; Tang, XQ; Wang, B; Wang, J; Xia, M; Yin, Y, 2021)
"We examined the effects of subarachnoid hemorrhage (SAH) and treatment with deferoxamine (DFO) or sympathectomy on vascular smooth muscle function, as well as the underlying mechanisms involved, by recording the responses to nor-adrenaline and serotonin in isolated carotid arteries in vitro."7.69Effect of deferoxamine and sympathectomy on vasospasm following subarachnoid hemorrhage. ( Akgün, M; Göksel, M; Kaya, T; Sarioglu, Y; Solak, O; Utkan, T, 1996)
"The role of endothelium-related factors in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH) has gained interest since the discovery of EDRF and of endothelin-1 (ET-1)."7.69Effects of deferoxamine and sympathectomy on endothelin-1-induced contraction and acetylcholine-induced relaxation following subarachnoid hemorrhage in carotid artery. ( Akgün, M; Düzcan, E; Sarioğlu, Y; Utkan, NZ; Utkan, T, 1997)
" Iron chelation and iron overload was achieved by deferoxamine mesylate or iron dextran injection."4.02Iron chelation suppresses secondary bleeding after intracerebral hemorrhage in angiotensin II-infused mice. ( Chen, WX; Feng, H; Ge, HF; Guo, C; Li, CC; Tang, XQ; Wang, B; Wang, J; Xia, M; Yin, Y, 2021)
"We examined the effects of subarachnoid hemorrhage (SAH) and treatment with deferoxamine (DFO) or sympathectomy on vascular smooth muscle function, as well as the underlying mechanisms involved, by recording the responses to nor-adrenaline and serotonin in isolated carotid arteries in vitro."3.69Effect of deferoxamine and sympathectomy on vasospasm following subarachnoid hemorrhage. ( Akgün, M; Göksel, M; Kaya, T; Sarioglu, Y; Solak, O; Utkan, T, 1996)
"The role of endothelium-related factors in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH) has gained interest since the discovery of EDRF and of endothelin-1 (ET-1)."3.69Effects of deferoxamine and sympathectomy on endothelin-1-induced contraction and acetylcholine-induced relaxation following subarachnoid hemorrhage in carotid artery. ( Akgün, M; Düzcan, E; Sarioğlu, Y; Utkan, NZ; Utkan, T, 1997)
" Dose-response curves were made for each of the additives (n> or =4 for each dose)."1.31Improving the preservation of isolated rat skeletal muscles stored for 16 hours at 4 degrees C. ( Bär, DP; de Smet, M; de With, MC; Kon, M; Kroese, AB; van der Heijden, EP; Werker, PM, 2000)
"Reperfusion injury is a phenomenon complicating microvascular reconstruction."1.29Limiting impairment of muscle function following ischemia and reperfusion in rabbits. ( Huang, L; Klitzman, B; Panza, W; Serafin, D; Zavitsanos, G, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's10 (71.43)18.2507
2000's1 (7.14)29.6817
2010's1 (7.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Wang, J1
Tang, XQ1
Xia, M1
Li, CC1
Guo, C1
Ge, HF1
Yin, Y1
Wang, B1
Chen, WX1
Feng, H1
Anuvarbekova, A1
Fincan, GS1
Vural, IM1
Ozger, SI1
Ercan, ZS1
Utkan, T3
Sarioglu, Y3
DANIEL, EE1
IRWIN, J1
Hattori, Y1
Imamura, M1
Akaishi, Y1
Kanno, M1
Iesaki, T1
Okada, T1
Yamaguchi, H1
Ochi, R1
Vollrath, B1
Chan, P1
Findlay, M1
Cook, D1
Zavitsanos, G1
Huang, L1
Panza, W1
Serafin, D1
Klitzman, B1
Kaya, T1
Akgün, M2
Göksel, M1
Solak, O1
Düzcan, E1
Utkan, NZ1
Nasu, T1
Suzuki, N1
van der Heijden, EP1
Kroese, AB1
Werker, PM1
de With, MC1
de Smet, M1
Kon, M1
Bär, DP1
Tachado, SD1
Akhtar, RA1
Zhou, CJ1
Abdel-Latif, AA1
Ratz, PH1
Lattanzio, FA1
Bény, JL1
von der Weid, PY1

Other Studies

14 other studies available for deferoxamine and Muscle Contraction

ArticleYear
Iron chelation suppresses secondary bleeding after intracerebral hemorrhage in angiotensin II-infused mice.
    CNS neuroscience & therapeutics, 2021, Volume: 27, Issue:11

    Topics: Angiotensin II; Animals; Cerebral Hemorrhage; Deferoxamine; Drug Combinations; Hemoglobins; Hyperten

2021
Investigation of enhancement effects of nicotine on cholinergic neurotransmission in isolated rabbit gastric fundus: role of antioxidants.
    Autonomic & autacoid pharmacology, 2010, Volume: 30, Issue:3

    Topics: Acetylcholine; Allopurinol; Animals; Antioxidants; Atropine; Cholinergic Fibers; Deferoxamine; Elect

2010
ON THE MECHANISMS WHEREBY EDTA, EGTA, DPTA, OXALATE, DESFERRIOXAMINE, AND 1,10-PHENANTHROLINE AFFECT CONTRACTILITY OF RAT UTERUS.
    Canadian journal of physiology and pharmacology, 1965, Volume: 43

    Topics: Calcium; Chelating Agents; Deferoxamine; Edetic Acid; Egtazic Acid; Female; Humans; Magnesium; Muscl

1965
Inotropic changes induced by fluoroaluminates in rabbit left atrial muscles: possible involvement of G proteins.
    British journal of pharmacology, 1995, Volume: 114, Issue:1

    Topics: Aluminum; Animals; Atrial Function, Left; Cyclic AMP; Deferoxamine; Dose-Response Relationship, Drug

1995
Inhibition of vasoactive amine induced contractions of vascular smooth muscle by hydrogen peroxide in rabbit aorta.
    Cardiovascular research, 1994, Volume: 28, Issue:7

    Topics: Acetylcholine; Animals; Antioxidants; Aorta; Deferoxamine; Depression, Chemical; Endothelium, Vascul

1994
Lazaroids and deferoxamine attenuate the intracellular effects of oxyhaemoglobin in vascular smooth muscle.
    Cardiovascular research, 1995, Volume: 30, Issue:4

    Topics: Animals; Antioxidants; Calcium; Cell Line; Cell Survival; Chelating Agents; Chromans; Deferoxamine;

1995
Limiting impairment of muscle function following ischemia and reperfusion in rabbits.
    Journal of reconstructive microsurgery, 1996, Volume: 12, Issue:3

    Topics: Animals; Calcium Channel Blockers; Deferoxamine; Dimethyl Sulfoxide; Forelimb; Free Radical Scavenge

1996
Effect of deferoxamine and sympathectomy on vasospasm following subarachnoid hemorrhage.
    Pharmacology, 1996, Volume: 52, Issue:6

    Topics: Animals; Carotid Arteries; Deferoxamine; Disease Models, Animal; Female; Ischemic Attack, Transient;

1996
Effects of deferoxamine and sympathectomy on endothelin-1-induced contraction and acetylcholine-induced relaxation following subarachnoid hemorrhage in carotid artery.
    General pharmacology, 1997, Volume: 28, Issue:1

    Topics: Acetylcholine; Animals; Carotid Artery Diseases; Carotid Artery, Common; Deferoxamine; Endothelin-1;

1997
Effects of aluminum ions on K(+)-induced contraction in ileal longitudinal smooth muscle.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1998, Volume: 120, Issue:1

    Topics: Aluminum; Animals; Calcium; Cations; Chelating Agents; Colon; Deferoxamine; Drug Interactions; Guine

1998
Improving the preservation of isolated rat skeletal muscles stored for 16 hours at 4 degrees C.
    Transplantation, 2000, Apr-15, Volume: 69, Issue:7

    Topics: Animals; Antioxidants; Chelating Agents; Chromans; Cryopreservation; Cyclic N-Oxides; Deferoxamine;

2000
Effects of isoproterenol and forskolin on carbachol- and fluoroaluminate-induced polyphosphoinositide hydrolysis, inositol trisphosphate production, and contraction in bovine iris sphincter smooth muscle: interaction between cAMP and IP3 second messenger
    Cellular signalling, 1992, Volume: 4, Issue:1

    Topics: Aluminum; Animals; Carbachol; Cattle; Colforsin; Cyclic AMP; Deferoxamine; Fluorine; Hydrolysis; Ino

1992
L-type Ca2+ channel desensitization by F- reduces PhE-induced increase in [Ca2+]i but not stress.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Hydrogen peroxide: an endogenous smooth muscle cell hyperpolarizing factor.
    Biochemical and biophysical research communications, 1991, Apr-15, Volume: 176, Issue:1

    Topics: Animals; Coronary Vessels; Deferoxamine; Dinoprost; Endothelium, Vascular; Free Radicals; Hydrogen P

1991