deferoxamine has been researched along with Mitochondrial Diseases in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is also the second case report of a Pearson patient suffering from severe iron overload and liver disease that responded to therapy with deferoxamine." | 3.74 | Pearson syndrome in an infant heterozygous for C282Y allele of HFE gene. ( Augoustides-Savvopoulou, P; Farmaki, E; Karatza, E; Kefala-Agoropoulou, K; Lazaridou, A; Roilides, E; Tsantali, H; Tsiouris, J, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kefala-Agoropoulou, K | 2 |
| Roilides, E | 2 |
| Lazaridou, A | 1 |
| Karatza, E | 1 |
| Farmaki, E | 2 |
| Tsantali, H | 1 |
| Augoustides-Savvopoulou, P | 1 |
| Tsiouris, J | 2 |
| Velegraki, A | 1 |
2 other studies available for deferoxamine and Mitochondrial Diseases
| Article | Year |
|---|---|
Pearson syndrome in an infant heterozygous for C282Y allele of HFE gene.
Topics: Anemia, Sideroblastic; Deferoxamine; Fatal Outcome; Female; Hemochromatosis; Hemochromatosis Protein | 2007 |
Cutaneous zygomycosis in an infant with Pearson syndrome.
Topics: Amphotericin B; Anemia, Neonatal; Anemia, Sideroblastic; Antifungal Agents; Catheters, Indwelling; D | 2008 |