deferoxamine has been researched along with Meningitis, Meningococcal in 1 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Meningitis, Meningococcal: A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyrophosphate was shown to participate in iron transfer from transferrin to ferritin." | 1.40 | Pyrophosphate-mediated iron acquisition from transferrin in Neisseria meningitidis does not require TonB activity. ( Biville, F; Brézillon, C; Giorgini, D; Taha, MK, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biville, F | 1 |
| Brézillon, C | 1 |
| Giorgini, D | 1 |
| Taha, MK | 1 |
1 other study available for deferoxamine and Meningitis, Meningococcal
| Article | Year |
|---|---|
Pyrophosphate-mediated iron acquisition from transferrin in Neisseria meningitidis does not require TonB activity.
Topics: Animals; Bacterial Proteins; Biological Transport; Deferoxamine; Diphosphates; Disease Models, Anima | 2014 |