deferoxamine has been researched along with Malignant Melanoma in 11 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mechanism of action of the clinically used iron(III) chelator, desferrioxamine (DFO), on preventing iron (Fe) uptake from transferrin (Tf) has been investigated using the human melanoma cell line SK-MEL-28." | 7.69 | The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell. ( Baker, E; Ponka, P; Richardson, D, 1994) |
| "The effect of ferric ammonium citrate (FAC) and desferrioxamine (DFO) on membrane iron and transferrin uptake have been investigated using SK-MEL-28 human melanoma cells which express the membrane-bound transferrin homologue, melanotransferrin, at high concentrations." | 7.68 | The effect of desferrioxamine and ferric ammonium citrate on the uptake of iron by the membrane iron-binding component of human melanoma cells. ( Baker, E; Richardson, DR, 1992) |
| "The effects of ferric ammonium citrate (FAC) and desferrioxamine (DFO) on iron (Fe), and transferrin (Tf) uptake have been investigated using SK-MEL-28 human melanoma cells, which express the Tf homologue, melanotransferrin, in high concentrations." | 7.68 | Two mechanisms of iron uptake from transferrin by melanoma cells. The effect of desferrioxamine and ferric ammonium citrate. ( Baker, E; Richardson, D, 1992) |
| "The role of the transferrin homologue, melanotransferrin (p97), in iron metabolism has been studied using the human melanoma cell line, SK-MEL-28, which expresses this antigen in high concentrations." | 7.68 | The release of iron and transferrin from the human melanoma cell. ( Baker, E; Richardson, DR, 1991) |
| "The role of the transferrin homologue, melanotransferrin (p97), in iron metabolism has been studied using the human melanoma cell line, SK-MEL-28, which expresses this antigen in high concentrations." | 7.68 | The uptake of iron and transferrin by the human malignant melanoma cell. ( Baker, E; Richardson, DR, 1990) |
| "The mechanism of action of the clinically used iron(III) chelator, desferrioxamine (DFO), on preventing iron (Fe) uptake from transferrin (Tf) has been investigated using the human melanoma cell line SK-MEL-28." | 3.69 | The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell. ( Baker, E; Ponka, P; Richardson, D, 1994) |
| "The effect of ferric ammonium citrate (FAC) and desferrioxamine (DFO) on membrane iron and transferrin uptake have been investigated using SK-MEL-28 human melanoma cells which express the membrane-bound transferrin homologue, melanotransferrin, at high concentrations." | 3.68 | The effect of desferrioxamine and ferric ammonium citrate on the uptake of iron by the membrane iron-binding component of human melanoma cells. ( Baker, E; Richardson, DR, 1992) |
| "The effects of ferric ammonium citrate (FAC) and desferrioxamine (DFO) on iron (Fe), and transferrin (Tf) uptake have been investigated using SK-MEL-28 human melanoma cells, which express the Tf homologue, melanotransferrin, in high concentrations." | 3.68 | Two mechanisms of iron uptake from transferrin by melanoma cells. The effect of desferrioxamine and ferric ammonium citrate. ( Baker, E; Richardson, D, 1992) |
| "The role of the transferrin homologue, melanotransferrin (p97), in iron metabolism has been studied using the human melanoma cell line, SK-MEL-28, which expresses this antigen in high concentrations." | 3.68 | The release of iron and transferrin from the human melanoma cell. ( Baker, E; Richardson, DR, 1991) |
| "The human melanoma cell line, SK-MEL-28, expresses high levels of melanotransferrin." | 3.68 | The uptake of inorganic iron complexes by human melanoma cells. ( Baker, E; Richardson, D, 1991) |
| "The role of the transferrin homologue, melanotransferrin (p97), in iron metabolism has been studied using the human melanoma cell line, SK-MEL-28, which expresses this antigen in high concentrations." | 3.68 | The uptake of iron and transferrin by the human malignant melanoma cell. ( Baker, E; Richardson, DR, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 7 (63.64) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SA | 1 |
| Son, YO | 1 |
| Kook, SH | 1 |
| Choi, KC | 1 |
| Lee, JC | 1 |
| Ameri, K | 1 |
| Hammond, EM | 1 |
| Culmsee, C | 1 |
| Raida, M | 1 |
| Katschinski, DM | 1 |
| Wenger, RH | 1 |
| Wagner, E | 1 |
| Davis, RJ | 1 |
| Hai, T | 1 |
| Denko, N | 1 |
| Harris, AL | 1 |
| Iinuma, S | 1 |
| Farshi, SS | 1 |
| Ortel, B | 1 |
| Hasan, T | 1 |
| Richardson, D | 3 |
| Ponka, P | 1 |
| Baker, E | 6 |
| Hoffer, PB | 1 |
| Samuel, A | 1 |
| Bushberg, JT | 1 |
| Thakur, M | 1 |
| Richardson, DR | 3 |
| Hedley, D | 1 |
| Rugg, C | 1 |
| Musgrove, E | 1 |
| Taylor, I | 1 |
11 other studies available for deferoxamine and Malignant Melanoma
| Article | Year |
|---|---|
Ascorbic acid increases the activity and synthesis of tyrosinase in B16F10 cells through activation of p38 mitogen-activated protein kinase.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Deferoxamine; Disease Mo | 2011 |
Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway.
Topics: Acetylcysteine; Activating Transcription Factor 3; Amino Acids, Dicarboxylic; Basic Helix-Loop-Helix | 2007 |
A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Division; | 1994 |
The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell.
Topics: Cell Division; Cell Membrane; Cell Membrane Permeability; Deferoxamine; Ferric Compounds; Humans; Io | 1994 |
Desferoxamine mesylate (Desferal): a contrast-enhancing agent for gallium-37 imaging.
Topics: Abscess; Animals; Deferoxamine; Drug Interactions; Gallium Radioisotopes; Image Enhancement; Melanom | 1979 |
The effect of desferrioxamine and ferric ammonium citrate on the uptake of iron by the membrane iron-binding component of human melanoma cells.
Topics: Cell Membrane; Deferoxamine; Ferric Compounds; Humans; Iron; Melanoma; Quaternary Ammonium Compounds | 1992 |
Two mechanisms of iron uptake from transferrin by melanoma cells. The effect of desferrioxamine and ferric ammonium citrate.
Topics: Biological Transport; Culture Media; Deferoxamine; Ferric Compounds; Humans; Iron; Kinetics; Melanom | 1992 |
The release of iron and transferrin from the human melanoma cell.
Topics: Antigens, Neoplasm; Cell Line; Deferoxamine; Humans; Iron; Iron Chelating Agents; Isoniazid; Kinetic | 1991 |
The uptake of inorganic iron complexes by human melanoma cells.
Topics: Ammonium Chloride; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Membrane; Citrates; Citric Acid; | 1991 |
The uptake of iron and transferrin by the human malignant melanoma cell.
Topics: Antigens, Neoplasm; Binding Sites; Cell Membrane; Deferoxamine; Endocytosis; Humans; Iodine Radioiso | 1990 |
Modulation of transferrin receptor expression by inhibitors of nucleic acid synthesis.
Topics: Animals; Cell Line; Cell Survival; Deferoxamine; DNA Replication; Flow Cytometry; Fluorescence; Huma | 1985 |