deferoxamine has been researched along with MS (Multiple Sclerosis) in 3 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic progressive Multiple Sclerosis is refractory to many conventional treatments." | 2.68 | Desferrioxamine in chronic progressive multiple sclerosis: a pilot study. ( LeVine, SM; Lynch, SG; Peters, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weigel, KJ | 1 |
| Lynch, SG | 2 |
| LeVine, SM | 2 |
| Peters, K | 1 |
| Hulet, SW | 1 |
| Heyliger, SO | 1 |
| Powers, S | 1 |
| Connor, JR | 1 |
1 review available for deferoxamine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Iron chelation and multiple sclerosis.
Topics: Animals; Chelation Therapy; Deferiprone; Deferoxamine; Humans; Iron; Iron Chelating Agents; Multiple | 2014 |
1 trial available for deferoxamine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Desferrioxamine in chronic progressive multiple sclerosis: a pilot study.
Topics: Adult; Antidotes; Chronic Disease; Deferoxamine; Female; Hearing Tests; Humans; Male; Middle Aged; M | 1996 |
1 other study available for deferoxamine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Oligodendrocyte progenitor cells internalize ferritin via clathrin-dependent receptor mediated endocytosis.
Topics: Animals; Binding, Competitive; Biological Transport; Brain; Cells, Cultured; Chelating Agents; Clath | 2000 |