deferoxamine has been researched along with MPTP Neurotoxicity Syndrome in 3 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| You, LH | 1 |
| Li, F | 1 |
| Wang, L | 1 |
| Zhao, SE | 1 |
| Wang, SM | 1 |
| Zhang, LL | 1 |
| Zhang, LH | 1 |
| Duan, XL | 1 |
| Yu, P | 1 |
| Chang, YZ | 1 |
| Aguirre, P | 1 |
| Mena, NP | 1 |
| Carrasco, CM | 1 |
| Muñoz, Y | 1 |
| Pérez-Henríquez, P | 1 |
| Morales, RA | 1 |
| Cassels, BK | 1 |
| Méndez-Gálvez, C | 1 |
| García-Beltrán, O | 1 |
| González-Billault, C | 1 |
| Núñez, MT | 1 |
| Guo, C | 1 |
| Hao, LJ | 1 |
| Yang, ZH | 1 |
| Chai, R | 1 |
| Zhang, S | 1 |
| Gu, Y | 1 |
| Gao, HL | 1 |
| Zhong, ML | 1 |
| Wang, T | 1 |
| Li, JY | 1 |
| Wang, ZY | 1 |
3 other studies available for deferoxamine and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Brain iron accumulation exacerbates the pathogenesis of MPTP-induced Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Apoptosis; bcl-2-Associated X Protein; Brain; Caspase 3; Ceruloplasmi | 2015 |
Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/MPTP-Lesioned Dopaminergic Neurons.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,2'-Dipyridyl; Animals; Antioxidants; Deferiprone; De | 2015 |
Deferoxamine-mediated up-regulation of HIF-1α prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Death; Cell Line, Tumor; Deferoxamine; Disease | 2016 |