deferoxamine has been researched along with Lung Neoplasms in 12 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effects of NTP on malignant mesothelioma (MM) and its modulation by l-ascorbate." | 1.43 | Biphasic effects of l-ascorbate on the tumoricidal activity of non-thermal plasma against malignant mesothelioma cells. ( Hori, M; Ito, F; Mizuno, M; Okazaki, Y; Richardson, DR; Shi, L; Tanaka, H; Toyokuni, S; Wang, Y, 2016) |
| "Mimosine treatment resulted in cell cycle blocks at the G(1)/S-phase border and in S phase." | 1.31 | Radiation sensitization of mammalian cells by metal chelators. ( Cook, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lovejoy, DB | 1 |
| Sharp, DM | 1 |
| Seebacher, N | 1 |
| Obeidy, P | 1 |
| Prichard, T | 1 |
| Stefani, C | 1 |
| Basha, MT | 1 |
| Sharpe, PC | 1 |
| Jansson, PJ | 1 |
| Kalinowski, DS | 1 |
| Bernhardt, PV | 1 |
| Richardson, DR | 2 |
| Kiraga, Ł | 1 |
| Cerutti, G | 1 |
| Braniewska, A | 1 |
| Strzemecki, D | 1 |
| Sas, Z | 1 |
| Boffi, A | 1 |
| Savino, C | 1 |
| Montemiglio, LC | 1 |
| Turnham, D | 1 |
| Seaton, G | 1 |
| Bonamore, A | 1 |
| Clarkson, R | 1 |
| Dabkowski, AM | 1 |
| Paisey, SJ | 1 |
| Taciak, B | 1 |
| Kucharzewska, P | 1 |
| Rygiel, TP | 1 |
| Król, M | 1 |
| Madajewski, B | 1 |
| Chen, F | 1 |
| Yoo, B | 1 |
| Turker, MZ | 1 |
| Ma, K | 1 |
| Zhang, L | 1 |
| Chen, PM | 1 |
| Juthani, R | 1 |
| Aragon-Sanabria, V | 1 |
| Gonen, M | 1 |
| Rudin, CM | 1 |
| Wiesner, U | 1 |
| Bradbury, MS | 1 |
| Brennan, C | 1 |
| Kuang, Y | 1 |
| Guo, W | 1 |
| Ling, J | 1 |
| Xu, D | 1 |
| Liao, Y | 1 |
| Zhao, H | 1 |
| Du, X | 1 |
| Wang, H | 1 |
| Xu, M | 1 |
| Song, H | 1 |
| Wang, T | 1 |
| Jing, B | 1 |
| Li, K | 1 |
| Hu, M | 1 |
| Wu, W | 1 |
| Deng, J | 1 |
| Wang, Q | 1 |
| Shi, L | 1 |
| Wang, Y | 1 |
| Ito, F | 1 |
| Okazaki, Y | 1 |
| Tanaka, H | 1 |
| Mizuno, M | 1 |
| Hori, M | 1 |
| Toyokuni, S | 1 |
| Nevo, I | 1 |
| Sagi-Assif, O | 1 |
| Edry Botzer, L | 1 |
| Amar, D | 1 |
| Maman, S | 1 |
| Kariv, N | 1 |
| Leider-Trejo, LE | 1 |
| Savelyeva, L | 1 |
| Schwab, M | 1 |
| Yron, I | 1 |
| Witz, IP | 1 |
| Suchaoin, W | 1 |
| Chanvorachote, P | 1 |
| Kaiserová, H | 1 |
| den Hartog, GJ | 1 |
| Simůnek, T | 1 |
| Schröterová, L | 1 |
| Kvasnicková, E | 1 |
| Bast, A | 1 |
| Koizumi, K | 1 |
| Tonami, N | 1 |
| Hisada, K | 1 |
| Dreicer, R | 1 |
| Kemp, JD | 1 |
| Stegink, LD | 1 |
| Cardillo, T | 1 |
| Davis, CS | 1 |
| Forest, PK | 1 |
| See, WA | 1 |
| Jiménez, LA | 1 |
| Thompson, J | 1 |
| Brown, DA | 1 |
| Rahman, I | 1 |
| Antonicelli, F | 1 |
| Duffin, R | 1 |
| Drost, EM | 1 |
| Hay, RT | 1 |
| Donaldson, K | 1 |
| MacNee, W | 1 |
| Cook, J | 1 |
1 trial available for deferoxamine and Lung Neoplasms
| Article | Year |
|---|---|
A phase II trial of deferoxamine in patients with hormone-refractory metastatic prostate cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Creatinine; Deferoxami | 1997 |
11 other studies available for deferoxamine and Lung Neoplasms
| Article | Year |
|---|---|
Novel second-generation di-2-pyridylketone thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Copp | 2012 |
Biodistribution PET/CT Study of Hemoglobin-DFO-
Topics: Animals; Cell Line, Tumor; Coordination Complexes; Deferoxamine; Drug Carriers; Drug Delivery System | 2020 |
Molecular Engineering of Ultrasmall Silica Nanoparticle-Drug Conjugates as Lung Cancer Therapeutics.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Deferoxamine; Drug De | 2020 |
Iron-dependent CDK1 activity promotes lung carcinogenesis via activation of the GP130/STAT3 signaling pathway.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma of Lung; Animals; Carcinogenesis; C | 2019 |
Biphasic effects of l-ascorbate on the tumoricidal activity of non-thermal plasma against malignant mesothelioma cells.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Ascorbic Acid; Autophagy; Cell Line, Tumor; Cell Sur | 2016 |
Generation and characterization of novel local and metastatic human neuroblastoma variants.
Topics: Adrenal Gland Neoplasms; Animals; Cell Line, Tumor; Cell Proliferation; Deferoxamine; Disease Models | 2008 |
Caveolin-1 attenuates hydrogen peroxide-induced oxidative damage to lung carcinoma cells.
Topics: Antioxidants; Carcinoma, Non-Small-Cell Lung; Caveolin 1; Cell Death; Cell Line, Tumor; Deferoxamine | 2012 |
Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin.
Topics: Aldehydes; Antibiotics, Antineoplastic; Apoptosis; Bleomycin; Cell Line, Tumor; Cell Proliferation; | 2006 |
Deferoxamine mesylate enhancement of 67Ga tumor-to-blood ratios and tumor imaging.
Topics: Animals; Breast Neoplasms; Deferoxamine; Female; Gallium Radioisotopes; Hodgkin Disease; Humans; Lun | 1982 |
Activation of NF-kappaB by PM(10) occurs via an iron-mediated mechanism in the absence of IkappaB degradation.
Topics: Adenocarcinoma; Air Pollutants; Cell Nucleus; Deferoxamine; DNA; DNA-Binding Proteins; Drug Interact | 2000 |
Radiation sensitization of mammalian cells by metal chelators.
Topics: Animals; Cell Cycle; Chelating Agents; Colony-Forming Units Assay; Cricetinae; Cricetulus; Deferipro | 2001 |